Sudden death of two horses associated with pulmonary aspergillosis.
Abstract: The sudden death of two horses was attributed to the rapid and acute development of pulmonary aspergillosis. One horse was making excellent postoperative progress after a jejunal resection and anastomosis for intestinal adhesions. The other horse was being treated routinely for equine protozoal myeloencephalitis (EPM). Signs of fever and an increased respiratory rate were detected shortly before death in the first horse, but no premonitory clinical signs characteristic of pulmonary infection were detected in the horse being treated for EPM. Both horses developed rapidly debilitating, acute pulmonary mycosis and died unexpectedly.
Publication Date: 1999-08-19 PubMed ID: 10452392DOI: 10.1136/vr.145.1.16Google Scholar: Lookup
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Summary
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The research article investigates the sudden death of two horses linked to a severe lung infection, pulmonary aspergillosis. Both horses, one recovering post-surgery and the other treated for a typical equine neurological disorder, showed no major signs hinting a lung disease prior to their unexpected death.
Research Background and Objective
- The research focuses on two cases where horses died suddenly, and these deaths were associated with pulmonary aspergillosis, a severe lung infection caused by the fungus Aspergillus.
- The primary aim of this study was to discern the underlying cause of the sudden death of the horses and raise awareness about rapid pulmonary infections in horses.
Horses’ Medical Condition Before Death
- One of the horses was recovering after a successful intestinal surgery while the other horse was having a standard treatment for equine protozoal myeloencephalitis (EPM), a common nervous system disorder in horses.
- The postoperative horse showed signs of fever and increased breathing rate shortly before its death. Conversely, the EPM-treated horse didn’t show any distinct sings suggestive of a lung infection.
Research Findings
- The research found that both horses died due to a sudden onset of acute pulmonary mycosis, a fungal lung infection.
- The study indicates that these horses developed a rapidly debilitating condition with severe consequences without displaying traditional symptoms of the disease, highlighting the covert and fatal potential of such infections.
Implications and Conclusions
- These findings urge increased vigilance for pulmonary infections in equine medical care, regardless of the lack of typical clinical signs.
- As these horses were dealing with other health conditions, attention must be paid to the possibility of such co-occurring, possibly opportunistic infections.
- The research underscores the crucial need for further studies on the prevention and early detection of pulmonary aspergillosis and similar infections in horses.
Cite This Article
APA
Johnson PJ, Moore LA, Mrad DR, Turk JR, Wilson DA.
(1999).
Sudden death of two horses associated with pulmonary aspergillosis.
Vet Rec, 145(1), 16-20.
https://doi.org/10.1136/vr.145.1.16 Publication
Researcher Affiliations
- Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia 65211, USA.
MeSH Terms
- Acute Disease
- Animals
- Aspergillosis / pathology
- Aspergillosis / veterinary
- Death, Sudden / pathology
- Death, Sudden / veterinary
- Horse Diseases / microbiology
- Horses
- Lung Diseases, Fungal / pathology
- Lung Diseases, Fungal / veterinary
- Male
Citations
This article has been cited 5 times.- Dobiáš R, Jahn P, Tóthová K, Dobešová O, Višňovská D, Patil R, Škríba A, Jaworská P, Škorič M, Podojil L, Kantorová M, Mrázek J, Krejčí E, Stevens DA, Havlíček V. Diagnosis of Aspergillosis in Horses. J Fungi (Basel) 2023 Jan 25;9(2).
- Rodríguez N, Whitfield-Cargile CM, Chamoun-Emanuelli AM, Hildreth E, Jordan W, Coleman MC. Nasopharyngeal bacterial and fungal microbiota in normal horses and horses with nasopharyngeal cicatrix syndrome. J Vet Intern Med 2021 Nov;35(6):2897-2911.
- Hattab J, Vulcano A, D'Arezzo S, Verni F, Tiscar PG, Lanteri G, Gjurcevic E, Tosi U, Marruchella G. Aspergillus Section Fumigati Pneumonia and Oxalate Nephrosis in a Foal. Pathogens 2021 Aug 26;10(9).
- Headley SA, Müller MC, de Oliveira TES, Barros Gil Duarte CA, Valente Pereira PF, Vieira MV, Cunha CW, Flores EF, Lisbôa JAN, Pretto-Giordano LG. Diphtheric aspergillosis tracheitis with gastrointestinal dissemination secondary to viral infections in a dairy calf. Microb Pathog 2020 Dec;149:104497.
- Headley SA, de Carvalho PH, Cunha Filho LF, Yamamura AA, Okano W. Equine pulmonary aspergillosis with encephalitic, myocardial, and renal dissemination. Mycopathologia 2014 Feb;177(1-2):129-35.
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