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The Veterinary clinics of North America. Equine practice2005; 21(3); 547-v; doi: 10.1016/j.cveq.2005.07.002

Systemic therapies for joint disease in horses.

Abstract: Systemic therapies for joint disease may be prescribed when a single joint is involved or when multiple sites are affected. The precise therapeutic regimen recommended depends on the duration,cause, and site(s) of injury and is often an adjunct to intra-articular or supportive therapies. If the clinical signs of joint disease are acute and moderate in severity, nonsteroidal anti-inflammatory drugs are often administered to alleviate pain and inflammation. When aiming for more of a generalized maintenance or chondro-protective regimen, an alternative medication, such as hyaluronan,polysulfated glycosaminoglycan, or a nutraceutical will commonly be prescribed.
Publication Date: 2005-11-22 PubMed ID: 16297720DOI: 10.1016/j.cveq.2005.07.002Google Scholar: Lookup
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Summary

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The research article discusses the administration of systemic therapies for treating joint disease in horses. The therapy varies depending on the duration, cause, and location of the disease and can be used as an additional treatment with intra-articular or supportive therapies.

Introduction to the Research Article

The main focus of this research is to explore the use of systemic therapies to manage and treat joint diseases in horses. The study emphasizes the customization of the therapeutic regimen based on individual criteria: the duration, cause, and site(s) of injury in a horse. It also looks at the possibility of combining these treatments with intra-articular or supportive therapies.

Use of Systemic Therapies for Single or Multiple Joint Involvement

  • Systemic therapies work on the entire body rather than focusing on a specific joint or area, making them useful for both single and multiple joint disease cases.
  • Depending on the extent of disease involvement, systemic therapies may be recommended as the first line of treatment or supplemented with other methods.

Significance of the Cause, Duration, and Site of Injury in Choosing Therapeutic Regimens

  • The therapeutic program’s formulation depends heavily on the disease’s cause, how long the disease has lasted, and where the disease is located.
  • Taking these factors into account allows for a more strategic and effective treatment plan to reduce pain and inflammation.

The Usage of Nonsteroidal Anti-Inflammatory Drugs (NSAID)

  • When the joint disease displays acute and moderate signs, NSAIDs are commonly used to address pain and inflammation.
  • These drugs work by reducing the production of compounds causing inflammation and pain, providing relief to the horse.

Alternative Medication for Generalized Maintenance or Chondro-protective Regimen

  • In cases where a more generalized maintenance approach or chondro-protective regimen is required, other medications like hyaluronan, polysulfated glycosaminoglycan, or nutraceuticals are often prescribed.
  • These treatments can offer protection to the cartilage and contribute to overall joint health.

Cite This Article

APA
Fortier LA. (2005). Systemic therapies for joint disease in horses. Vet Clin North Am Equine Pract, 21(3), 547-v. https://doi.org/10.1016/j.cveq.2005.07.002

Publication

ISSN: 0749-0739
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 21
Issue: 3
Pages: 547-v

Researcher Affiliations

Fortier, Lisa A
  • Department of Clinical Sciences, Veterinary Medical College, VMC C3-181, Cornell University, Ithaca, NY 14853, USA. laf4@cornell.edu

MeSH Terms

  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Combined Modality Therapy / methods
  • Combined Modality Therapy / veterinary
  • Glycosaminoglycans / therapeutic use
  • Horse Diseases / drug therapy
  • Horse Diseases / therapy
  • Horses
  • Hyaluronic Acid / therapeutic use
  • Joint Diseases / drug therapy
  • Joint Diseases / therapy
  • Joint Diseases / veterinary

References

This article includes 66 references

Citations

This article has been cited 2 times.
  1. Gregg SR, Barshick MR, Johnson SE. Intravenous Injection of Sodium Hyaluronate Diminishes Basal Inflammatory Gene Expression in Equine Skeletal Muscle. Animals (Basel) 2023 Sep 27;13(19).
    doi: 10.3390/ani13193030pubmed: 37835636google scholar: lookup
  2. Lamprecht ED, Williams CA. Biomarkers of antioxidant status, inflammation, and cartilage metabolism are affected by acute intense exercise but not superoxide dismutase supplementation in horses. Oxid Med Cell Longev 2012;2012:920932.
    doi: 10.1155/2012/920932pubmed: 22919442google scholar: lookup