The 2007 outbreak of equine influenza in Australia: lessons learned for international trade in horses.
- Journal Article
- Review
Summary
This research article discusses the 2007 outbreak of equine influenza in Australia, the associated failures in quarantine protocols, and the important lessons for international horse trade.
Introduction
The research begins by providing a contextual backdrop, explaining that in August 2007, Australia experienced its first outbreak of equine influenza. It highlights that the disease initially manifested within a quarantine facility intended for imported horses near Sydney and eventually infiltrated the broader horse population.
- The study indicates that after a widescale campaign, the disease was successfully eliminated, and Australia once again was declared free of the infestation.
Research Focus
The paper underscores that equine influenza was identified as a major risk associated with the live importation of horses into Australia even prior to the outbreak. Investigations after the incident revealed negligence towards adherence to these quarantine guidelines as a significant cause, mainly:
- The quarantine guidelines were implemented to alleviate the risk, but consistent non-compliance led to the outbreak.
- Moreover, it discusses that the immunity level of the horses, who were vaccinated under the import protocol, was discovered to be inadequate. Therefore, it is marked as a vital contributory factor in the spread of the ailment outside the specified quarantine premises.
Conclusion & Future implications
Concluding, this research is not only a historical review of the 2007 influenza outbreak in Australia but also an important lesson for the future, as it unearths some significant aspects regarding live horse trades. The study makes clear that spreading such infections can be effectively prevented by ensuring strict adherence to quarantine rules and developing optimal vaccination protocols for horses.
- It creates a pressing need to rectify these loopholes in order to maintain a healthy horse population and limit the implications of future potential outbreaks for the international trade of live horses.
Cite This Article
Publication
Researcher Affiliations
- Australian Animal Health Laboratory, Private Bag 24, Geelong VIC 3220, Australia.
MeSH Terms
- Animals
- Australia / epidemiology
- Commerce / legislation & jurisprudence
- Commerce / standards
- Disease Outbreaks / prevention & control
- Disease Outbreaks / veterinary
- Horse Diseases / epidemiology
- Horse Diseases / prevention & control
- Horses
- Influenza A Virus, H3N8 Subtype / immunology
- Influenza Vaccines / administration & dosage
- Orthomyxoviridae Infections / epidemiology
- Orthomyxoviridae Infections / prevention & control
- Orthomyxoviridae Infections / veterinary
- Quarantine / legislation & jurisprudence
- Quarantine / standards
- Vaccination / legislation & jurisprudence
- Vaccination / standards
- Vaccination / veterinary
Citations
This article has been cited 20 times.- Jiang S, Yang S, Zhang X, Fang Y, Guo Z, Ma Z, Wei X, Guo K, El-Ansary RE, Bayasgalan C, Wubshet AK, Zhang J. Evolutionary and structural insights into VP1 epitopes of representative SAT-type FMDV strains: implications for candidate vaccine selection. Vet Res 2025 Dec 15;56(1):227.
- Anderson C, Baha H, Boghdeh N, Barrera M, Alem F, Narayanan A. Interactions of Equine Viruses with the Host Kinase Machinery and Implications for One Health and Human Disease. Viruses 2023 May 13;15(5).
- Gonzalez-Obando J, Forero JE, Zuluaga-Cabrera AM, Ruiz-Saenz J. Equine Influenza Virus: An Old Known Enemy in the Americas. Vaccines (Basel) 2022 Oct 14;10(10).
- Manuja BK, Manuja A, Singh RK. Globalization and Livestock Biosecurity. Agric Res 2014;3(1):22-31.
- Cullinane A, Gahan J, Walsh C, Nemoto M, Entenfellner J, Olguin-Perglione C, Garvey M, Huang Fu TQ, Venner M, Yamanaka T, Barrandeguy M, Fernandez CJ. Evaluation of Current Equine Influenza Vaccination Protocols Prior to Shipment, Guided by OIE Standards. Vaccines (Basel) 2020 Feb 29;8(1).
- He W, Li G, Wang R, Shi W, Li K, Wang S, Lai A, Su S. Host-range shift of H3N8 canine influenza virus: a phylodynamic analysis of its origin and adaptation from equine to canine host. Vet Res 2019 Oct 30;50(1):87.
- Blanco-Lobo P, Rodriguez L, Reedy S, Oladunni FS, Nogales A, Murcia PR, Chambers TM, Martinez-Sobrido L. A Bivalent Live-Attenuated Vaccine for the Prevention of Equine Influenza Virus. Viruses 2019 Oct 11;11(10).
- Gahan J, Garvey M, Asmah Abd Samad R, Cullinane A. Whole Genome Sequencing of the First H3N8 Equine Influenza Virus Identified in Malaysia. Pathogens 2019 May 10;8(2).
- Miño S, Mojsiejczuk L, Guo W, Zhang H, Qi T, Du C, Zhang X, Wang J, Campos R, Wang X. Equine Influenza Virus in Asia: Phylogeographic Pattern and Molecular Features Reveal Circulation of an Autochthonous Lineage. J Virol 2019 Jul 1;93(13).
- Brister H, Barnum SM, Reedy S, Chambers TM, Pusterla N. Validation of two multiplex real-time PCR assays based on single nucleotide polymorphisms of the HA1 gene of equine influenza A virus in order to differentiate between clade 1 and clade 2 Florida sublineage isolates. J Vet Diagn Invest 2019 Jan;31(1):137-141.
- Kwaśnik M, Góra IM, Żmudziński JF, Rola J, Polak MP, Rożek W. Genetic Analysis of the M Gene of Equine Influenza Virus Strains Isolated in Poland, in the Context of the Asian-like Group Formation. J Vet Res 2018 Dec;62(4):405-412.
- Dilai M, Piro M, El Harrak M, Fougerolle S, Dehhaoui M, Dikrallah A, Legrand L, Paillot R, Fassi Fihri O. Impact of Mixed Equine Influenza Vaccination on Correlate of Protection in Horses. Vaccines (Basel) 2018 Oct 4;6(4).
- Singh RK, Dhama K, Karthik K, Khandia R, Munjal A, Khurana SK, Chakraborty S, Malik YS, Virmani N, Singh R, Tripathi BN, Munir M, van der Kolk JH. A Comprehensive Review on Equine Influenza Virus: Etiology, Epidemiology, Pathobiology, Advances in Developing Diagnostics, Vaccines, and Control Strategies. Front Microbiol 2018;9:1941.
- Gahan J, Garvey M, Gildea S, Gür E, Kagankaya A, Cullinane A. Whole-genome sequencing and antigenic analysis of the first equine influenza virus identified in Turkey. Influenza Other Respir Viruses 2018 May;12(3):374-382.
- Olguin Perglione C, Golemba MD, Torres C, Barrandeguy M. Molecular Epidemiology and Spatio-Temporal Dynamics of the H3N8 Equine Influenza Virus in South America. Pathogens 2016 Oct 16;5(4).
- Paillot R, El-Hage CM. The Use of a Recombinant Canarypox-Based Equine Influenza Vaccine during the 2007 Australian Outbreak: A Systematic Review and Summary. Pathogens 2016 Jun 10;5(2).
- Yamanaka T, Nemoto M, Bannai H, Tsujimura K, Kondo T, Matsumura T, Gildea S, Cullinane A. Evaluation of twenty-two rapid antigen detection tests in the diagnosis of Equine Influenza caused by viruses of H3N8 subtype. Influenza Other Respir Viruses 2016 Mar;10(2):127-33.
- Perglione CO, Gildea S, Rimondi A, Miño S, Vissani A, Carossino M, Cullinane A, Barrandeguy M. Epidemiological and virological findings during multiple outbreaks of equine influenza in South America in 2012. Influenza Other Respir Viruses 2016 Jan;10(1):37-46.
- Paillot R. A Systematic Review of Recent Advances in Equine Influenza Vaccination. Vaccines (Basel) 2014 Nov 14;2(4):797-831.
- Pusterla N, Kass PH, Mapes S, Wademan C, Akana N, Barnett C, MacKenzie C, Vaala W. Voluntary surveillance program for equine influenza virus in the United States from 2010 to 2013. J Vet Intern Med 2015 Jan;29(1):417-22.