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Home / Equine Research Bank / Pathogens / The Use of a Recombinant Canarypox-Based Equine Influenza Va...
Pathogens (Basel, Switzerland)2016; 5(2); 42; doi: 10.3390/pathogens5020042

The Use of a Recombinant Canarypox-Based Equine Influenza Vaccine during the 2007 Australian Outbreak: A Systematic Review and Summary.

Abstract: In 2007, Australia experienced the most extensive equine influenza outbreak observed in recent years. Extraordinary measures were rapidly implemented in order to control and prevent the spread of this highly contagious disease. The control strategy involved stringent movement restriction and disease surveillance, seconded by emergency post-outbreak vaccination strategies. Sixteen months after the first case and 12 months following the last reported case, Australia regained its equine influenza-free OIE status. This systematic review reports and summarises information relating to the implementation of emergency vaccination during the 2007 Australian equine influenza outbreak, including the choice of vaccine and implementation strategies.
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Publication Date: 2016-06-10 PubMed ID: 27294963PubMed Central: PMC4931393DOI: 10.3390/pathogens5020042Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article gives a detailed account of the emergency vaccination strategies used during the 2007 equine influenza outbreak in Australia. It assesses the effectiveness of a recombinant canarypox-based vaccine in controlling the disease and helps Australia regain its equine influenza-free status.

Summary of Outbreak and Emergency Measures

  • The research opens with a description of the 2007 equine influenza outbreak in Australia, noted to be one of the most extensive in recent years.
  • The preventative measures taken by the Australian government to control the spread of this highly contagious disease are explained. These measures included strict travel restrictions and intense disease surveillance.

    • Vaccination Strategies

    • The researchers go on to describe the emergency vaccination strategies implemented during the outbreak.
    • This included the choice of a vaccine to combat the disease, which was a recombinant canarypox-based equine influenza vaccine. Recombinant vaccines are created by inserting genetic material from the pathogen into a separate virus, in this case a canarypox virus, that will not cause illness. They are considered safe and effective.
    • Details on how the vaccination program was rolled out during the outbreak are also provided, giving insights into how the emergency vaccination strategies were put into action.

      • Success of Vaccination Strategy

      • The paper discusses how effective these emergency measures were. Sixteen months after the first reported case of influenza and twelve months after the last reported case, Australia was declared free of equine influenza by the World Organisation for Animal Health (OIE).
      • This suggested that the use of the recombinant canarypox-based equine influenza vaccine, alongside other preventative measures, was successful in controlling and eradicating the disease.

        • Systematic Review and Summary

        • The research article is a systematic review, which means it aims to locate all pertinent information on the subject to generate a comprehensive summary of the existing data.
        • The purpose of this review is to collate and summarise information related to the implementation of the emergency vaccination during the 2007 equine influenza outbreak.

Cite This Article

APA
Paillot R, El-Hage CM. (2016). The Use of a Recombinant Canarypox-Based Equine Influenza Vaccine during the 2007 Australian Outbreak: A Systematic Review and Summary. Pathogens, 5(2), 42. https://doi.org/10.3390/pathogens5020042

Publication

Pathogens (Basel, Switzerland)
ISSN: 2076-0817
NlmUniqueID: 101596317
Country: Switzerland
Language: English
Volume: 5
Issue: 2
PII: 42

Researcher Affiliations

Paillot, Romain
  • Animal Health Trust, Lanwades Park, Kentford Newmarket, CB8 7UU Suffolk, UK. romain.paillot@aht.org.uk.
El-Hage, Charles M
  • The Centre for Equine Infectious Diseases, Veterinary Pre-Clinical Centre, University of Melbourne, VIC 3010, Australia. cmeh@unimelb.edu.au.

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Citations

This article has been cited 1 times.
  1. Singh RK, Dhama K, Karthik K, Khandia R, Munjal A, Khurana SK, Chakraborty S, Malik YS, Virmani N, Singh R, Tripathi BN, Munir M, van der Kolk JH. A Comprehensive Review on Equine Influenza Virus: Etiology, Epidemiology, Pathobiology, Advances in Developing Diagnostics, Vaccines, and Control Strategies.. Front Microbiol 2018;9:1941.
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