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Home / Equine Research Bank / Front Bioeng Biotechnol / Three-Dimensional Modeling and In Silico Kinematic Evaluatio...
Frontiers in bioengineering and biotechnology2022; 10; 817300; doi: 10.3389/fbioe.2022.817300

Three-Dimensional Modeling and In Silico Kinematic Evaluation of Interspinous Ligament Desmotomy in Horses.

Abstract: Interspinous ligament desmotomy (ISLD) has been shown to improve the comfort of horses diagnosed with overriding dorsal spinous processes (DSP), but its effects on spine mobility are unknown. To objectively quantify the change in mobility of thoracic vertebrae following ISLD using CT and medical modeling software. Prospective cadaveric manipulation of seven equine thoracolumbar spines collected from T11-L1. Spines were collected from T11-L1 with the musculature intact. Flexion and extension phases were achieved with a ratchet device calibrated to 2000N. Bone volume CT scans were performed in resting, flexion, and extension phase preoperatively. Interspinous ligament desmotomy was performed at each intervertebral space ( = 8), and bone volume CT imaging was repeated for each phase. The spinal sections were individually segmented and imported into medical software for kinematic evaluation. T11 of each phase were superimposed, the distance between each dorsal spinous process, the total length of the spine, and the maximal excursion of the first lumbar vertebra along with angular rotational information were recorded. The mean distance between each dorsal spinous process increased by 5.6 ± 4.9 mm, representing a 24 ± 21% increase in mobility following ISLD. L1 dorsoventral excursion increased by 15.3 ± 11.9 mm, craniocaudal motion increased by 6.9 ± 6.5 mm representing a 47 ± 36.5% and 14.5 ± 13.7% increase, respectively. The rotation of L1 about the mediolateral axis increased by 6.5 post-ISLD. ISLD increases dorsoventral, craniocaudal, and rotational motion of the equine spine. The computer modeling methodology used here could be used to evaluate multiplanar spinal kinematics between treatments.
Copyright © 2022 Biedrzycki and Elane.
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Publication Date: 2022-04-01 PubMed ID: 35433641PubMed Central: PMC9012442DOI: 10.3389/fbioe.2022.817300Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research focuses on how Interspinous Ligament Desmotomy (ISLD) affects the mobility of horses’ spinal structure. The findings suggest that ISLD increases the mobility in several aspects, opening new possibilities for further treatments.

Objective and Methodology

  • The study aims to measure how the mobility of the thoracic vertebrae changes when horses undergo Interspinous Ligament Desmotomy (ISLD).
  • Horse cadavers were used as samples, with seven equine thoracolumbar spines, extending from T11-L1, prepared.
  • In order to manipulate the spines, the muscles surrounding these structures were retained.
  • Flexion and extension were achieved using a calibrated ratchet device.
  • Pre-operative CT scans were taken before the ISLD, in the resting, flexion and extension phases. Post-ISLD, the CT scans were repeated.

Experimental Procedure and Kinematic Evaluation

  • ISLD was performed in the area between each vertebra.
  • The CT scans were segmented to provide a detailed analysis of each spine section.
  • These segments were imported into a medical software to evaluate the changes in kinematic movement.
  • Several aspects were measured: the distance between dorsal spinous processes, total length, maximal movement of the first lumbar vertebra, and angular rotation information.

Results and Observations

  • The researchers noticed a 5.6 ± 4.9mm increase in the distance between dorsal spinous processes. This is interpreted as an increased mobility post-ISLD by 24 ± 21%.
  • The motion of the first lumbar vertebra, L1, increased in multiple dimensions. The dorsoventral motion increased by 15.3 ± 11.9mm, and the craniocaudal motion increased by 6.9 ± 6.5mm, representing a 47 ± 36.5%, and a 14.5 ± 13.7% increase in motion, respectively.
  • Post-ISLD, the rotation of L1 about the mediolateral axis also increased by 6.5.

Conclusions and Implications

  • The study supports the hypothesis that ISLD increases the spine’s mobility in dorsoventral, craniocaudal, and rotational motions, which could improve comfort for horses diagnosed with overriding dorsal spinous processes (DSP).
  • The study’s findings suggest the methodology applied using advanced imaging and software could be replicated for future research into multiplanar spinal kinematics in horses and potentially other animals.

Cite This Article

APA
Biedrzycki AH, Elane GL. (2022). Three-Dimensional Modeling and In Silico Kinematic Evaluation of Interspinous Ligament Desmotomy in Horses. Front Bioeng Biotechnol, 10, 817300. https://doi.org/10.3389/fbioe.2022.817300

Publication

Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
NlmUniqueID: 101632513
Country: Switzerland
Language: English
Volume: 10
Pages: 817300
PII: 817300

Researcher Affiliations

Biedrzycki, Adam Henry
  • University of Florida, Gainesville, United States.
Elane, George Louis
  • University of Florida, Gainesville, United States.

Conflict of Interest Statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Citations

This article has been cited 1 times.
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