Toxic Causes of Intestinal Disease in Horses.
Abstract: Because most poisonings occur by toxin ingestion, the gastrointestinal system is the first exposed and, in most cases, it is exposed to the highest toxin concentrations. Consequently, enterocyte damage is common. However, because many toxins produce organ-specific damage, and enterocyte necrosis is easily confused with autolysis, many gastrointestinal lesions are overlooked or overshadowed by other clinical and pathologic changes. The objective of this work is to review several common toxins and poisonous plants that produce primarily gastrointestinal disease.
Published by Elsevier Inc.
Publication Date: 2018-02-04 PubMed ID: 29397222DOI: 10.1016/j.cveq.2017.11.008Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
- Review
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The research paper discusses the various toxic substances that may cause intestinal diseases in horses, emphasizing on the frequently overlooked gastrointestinal lesions.
Overview of the Research
- The study investigates the harmful substances that may lead to intestinal diseases in horses. The focus of the study centers primarily on toxins and toxic plants that primarily affect the gastrointestinal system.
- Enterocyte damage is a common consequence because toxins typically reach high concentrations in the gastrointestinal system, being the first point of contact in the case of ingestion. However, these gastrointestinal lesions are often overlooked due to similarities they have with autolysis and because many toxins cause damage to specific organs.
Purpose and Objective of the Research
- The objective of this research was to widen the understanding of harmful substances that affect the gastrointestinal system in horses.
- The study aimed to emphasize the tendency to overlook gastrointestinal lesions during diagnosis, due to their resemblance to autolysis and the organ-specific damage caused by certain toxins.
The Research Findings
- Though the researcher’s findings are not explicitly provided in the abstract, it can be inferred from the abstract that the research may have highlighted the specific toxic substances that cause primary harm to the horse’s gastrointestinal tract.
- The study potentially identified some common symptoms observed in horses resulting from exposure and ingestion of toxins, allowing for better detection of toxin-induced intestinal diseases in horses.
Significance of the Research
- This research could be a significant contribution to veterinary medicine, especially for veterinarians dealing with equine health.
- The findings would potentially lead to better diagnosis and treatments of toxin-induced intestinal diseases in horses and raise awareness of the gravity of overlooked gastrointestinal lesions.
Cite This Article
APA
Stegelmeier BL, Davis TZ.
(2018).
Toxic Causes of Intestinal Disease in Horses.
Vet Clin North Am Equine Pract, 34(1), 127-139.
https://doi.org/10.1016/j.cveq.2017.11.008 Publication
Researcher Affiliations
- USDA/ARS Poisonous Plant Research Laboratory, 1150 East 1400 North, Logan, UT 84341, USA. Electronic address: bryan.stegelmeier@ars.usda.gov.
- USDA/ARS Poisonous Plant Research Laboratory, 1150 East 1400 North, Logan, UT 84341, USA.
MeSH Terms
- Animals
- Gastrointestinal Diseases / chemically induced
- Gastrointestinal Diseases / pathology
- Gastrointestinal Diseases / veterinary
- Horse Diseases / chemically induced
- Horse Diseases / pathology
- Horses
- Microcystins / poisoning
- Plants, Toxic / poisoning
Citations
This article has been cited 2 times.- Hostetter JM, Uzal FA. Gastrointestinal biopsy in the horse: overview of collection, interpretation, and applications. J Vet Diagn Invest 2022 May;34(3):376-388.
- Konarska A, Łotocka B. Glandular trichomes of Robinia viscosa Vent. var. hartwigii (Koehne) Ashe (Faboideae, Fabaceae)-morphology, histochemistry and ultrastructure. Planta 2020 Nov 12;252(6):102.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists