Twenty years later: a single-centre, repeat retrospective analysis of equine perioperative mortality and investigation of recovery quality.
Abstract: To determine the mortality rates associated with equine anaesthesia for elective and emergency (colic and non-colic) cases in one equine, university teaching hospital and to investigate the effect of several horse- and anaesthetic-related variables on anaesthetic recovery quality. Methods: Retrospective data analysis. Unassigned: In total, 1416 horses undergoing anaesthesia between May 2010 and December 2013. Methods: Patient information and details of the anaesthetic, recovery period and immediate complications were extracted from an archiving database. Statistical evaluation of factors affecting mortality included chi-squared tests and binary logistic regression. Factors affecting recovery quality were investigated using univariable and multivariable ordinal logistic regression. Statistical significance was set at p < 0.05. Results: Anaesthesia/recovery-related mortality was 1.1% for all cases, 0.9% for elective cases, 1.6% for colics and 0% for non-colic emergencies. Fractures and dislocations accounted for the majority (71.4%) of deaths. No intra-operative deaths occurred during the study period. Risk factors for mortality included increasing age and American Society of Anesthesiologist's (ASA) status but these and other factors were confounded by 'colic'. Non-fatal complications in the immediate recovery period included postanaesthetic myopathy/neuropathy and postanaesthetic respiratory obstruction. Recovery quality was associated with body mass (p = 0.016), ASA status 3 and 4 (p = 0.020 and 0.002, respectively), duration of anaesthesia (p < 0.001) and out-of-hours anaesthesia (p = 0.013). Although recovery quality was also influenced by age and breed-type, these factors were removed from the final model as age was highly associated with both ASA status (p < 0.001) and colic surgery (p < 0.001), and breed-type was a determinant of body mass. Conclusions: Anaesthetic/recovery-associated mortality was comparable to previously reported figures except intra-operative deaths were not reported. Fractures remained responsible for the largest proportion of recovery-associated deaths. Improvements to the recovery process that can reduce fracture occurrence are still required.
© 2015 Association of Veterinary Anaesthetists and the American College of Veterinary Anesthesia and Analgesia.
Publication Date: 2015-06-15 PubMed ID: 26081190DOI: 10.1111/vaa.12285Google Scholar: Lookup
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- Journal Article
Summary
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The research article is a comprehensive study that examines the equine perioperative mortality rates at a university teaching hospital. It also scrutinizes various factors that may influence the quality of anaesthetic recovery in horses.
Research Methodology
- The study involved a retrospective analysis of 1,416 horses that underwent anaesthesia between May 2010 and December 2013.
- Patient data along with details of the anaesthesia, recovery period, and immediate complications were extracted from a database. This information was subsequently analyzed using statistical tests such as chi-squared tests and binary logistic regression.
- Factors potentially impacting recovery quality were evaluated through univariable and multivariable ordinal logistic regression. The level of statistical significance was set at p < 0.05.
Study Findings
- The mortality rate related to anaesthesia and recovery was found to be 1.1% for all cases, 0.9% for elective cases, and 1.6% for colic cases. No deaths were observed for non-colic emergency cases.
- Majority of deaths (71.4%) were due to fractures and dislocations. No intra-operative deaths occurred during the study period.
- Age and American Society of Anesthesiologist’s (ASA) status were identified as risk factors for mortality, but these findings were influenced by the incidence of ‘colic’.
- Non-fatal complications observed during the immediate recovery phase included postanaesthetic myopathy/neuropathy and postanaesthetic respiratory obstruction.
- The quality of recovery was found to be influenced by body mass, ASA status 3 and 4, duration of anaesthesia, and out-of-hours anaesthesia.
- Although age and breed-type affected recovery quality, these factors were removed in the final model due to a high association with ASA status and surgery for colic.
Study Conclusion
- The anaesthetic/recovery-associated mortality rate was comparable to figures reported in previous studies, with the remarkable exception of zero intra-operative deaths.
- Fractures were the leading cause of recovery-associated deaths, suggesting a need for improved recovery protocol to minimize fracture occurrence.
Cite This Article
APA
Dugdale AH, Obhrai J, Cripps PJ.
(2015).
Twenty years later: a single-centre, repeat retrospective analysis of equine perioperative mortality and investigation of recovery quality.
Vet Anaesth Analg, 43(2), 171-178.
https://doi.org/10.1111/vaa.12285 Publication
Researcher Affiliations
- School of Veterinary Science, University of Liverpool, Neston, Wirral, UK.
- School of Veterinary Science, University of Liverpool, Neston, Wirral, UK.
- School of Veterinary Science, University of Liverpool, Neston, Wirral, UK.
MeSH Terms
- Anesthesia Recovery Period
- Anesthesia, General / mortality
- Anesthesia, General / veterinary
- Animals
- Colic / mortality
- Colic / surgery
- Colic / veterinary
- Elective Surgical Procedures / mortality
- Elective Surgical Procedures / veterinary
- Female
- Horse Diseases / surgery
- Horses
- Male
- Postoperative Complications / mortality
- Postoperative Complications / veterinary
- Retrospective Studies
Citations
This article has been cited 11 times.- Straticò P, Varasano V, Palozzo A, Guerri G, Celani G, Revelant O, Petrizzi L. Retrospective Study on Risk Factors and Short-Term Outcome of Horses Referred for Colic from 2016 to 2022.. Vet Sci 2022 Oct 3;9(10).
- Wilkens HL, Neudeck S, Kästner SBR. Nasal and tracheobronchial nitric oxide production and its influence on oxygenation in horses undergoing total intravenous anaesthesia.. BMC Vet Res 2022 Apr 11;18(1):134.
- Gozalo-Marcilla M, Bettschart-Wolfensberger R, Johnston M, Taylor PM, Redondo JI. Data Collection for the Fourth Multicentre Confidential Enquiry into Perioperative Equine Fatalities (CEPEF4) Study: New Technology and Preliminary Results.. Animals (Basel) 2021 Aug 30;11(9).
- Vermedal H, Valverde A, Sears W. Effect of anesthesia duration on the quality of recovery in horses undergoing elective and emergency surgeries using the same anesthetic protocol.. Can J Vet Res 2021 Jul;85(3):193-200.
- Gozalo-Marcilla M, Ringer SK. Recovery after General Anaesthesia in Adult Horses: A Structured Summary of the Literature.. Animals (Basel) 2021 Jun 14;11(6).
- Morris TB, Lumsden JM, Dunlop CI, Locke V, Sommerauer S, Hurcombe SDA. Clinical Assessment of an Ipsilateral Cervical Spinal Nerve Block for Prosthetic Laryngoplasty in Anesthetized Horses.. Front Vet Sci 2020;7:284.
- Santistevan L, Easley J, Ruple A, Monck S, Randall E, Wininger F, Packer RA. A pilot study of optical neuronavigation-guided brain biopsy in the horse using anatomic landmarks and fiducial arrays for patient registration.. J Vet Intern Med 2020 Jul;34(4):1642-1649.
- Laurenza C, Ansart L, Portier K. Risk Factors of Anesthesia-Related Mortality and Morbidity in One Equine Hospital: A Retrospective Study on 1,161 Cases Undergoing Elective or Emergency Surgeries.. Front Vet Sci 2019;6:514.
- Portier K, Ida KK. The ASA Physical Status Classification: What Is the Evidence for Recommending Its Use in Veterinary Anesthesia?-A Systematic Review.. Front Vet Sci 2018;5:204.
- Conde Ruiz C, Junot S. Successful Cardiopulmonary Resuscitation in a Sevoflurane Anaesthetized Horse That Suffered Cardiac Arrest at Recovery.. Front Vet Sci 2018;5:138.
- Niimura Del Barrio MC, David F, Hughes JML, Clifford D, Wilderjans H, Bennett R. A retrospective report (2003-2013) of the complications associated with the use of a one-man (head and tail) rope recovery system in horses following general anaesthesia.. Ir Vet J 2018;71:6.
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