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Journal of the American Veterinary Medical Association2005; 227(10); 1630-1635; doi: 10.2460/javma.2005.227.1630

Use of color Doppler echocardiography to assess the development of valvular regurgitation in Standardbred trotters.

Abstract: To evaluate the incidence and development of valvular regurgitation and its effect on racing performance in Standardbred trotters from 2 to 3.5 years of age. Methods: Longitudinal observational study. Methods: 103 horses. Methods: Horses were examined via echocardiographic imaging 4 times at 6-month intervals. Two-dimensional and M-mode echocardiographic examinations were performed in each horse, and color Doppler imaging was used to detect and evaluate regurgitant blood flow at each valve. Results: For all cardiac valves, the frequency of valvular regurgitation increased significantly during the 18-month study period. Regurgitation was mild in all valves in which it was detected, and no progression in severity was observed at any valve. Tricuspid regurgitation was more prevalent in horses that raced regularly and was diagnosed more frequently in males and horses with larger left ventricular mass and left ventricular internal diameter during diastole. No relationship between racing performance and valvular regurgitation was observed. Conclusions: The incidence of valvular regurgitation increased during the study period, and it was common at 3.5 years of age. It was not possible to determine whether the increase was a result of maturity or training. The study revealed that there is a high prevalence of mild valvular regurgitation at this age, but apparently, the regurgitation had no effect on racing performance in this age group. Whether regurgitation will progress or influence future performance is not known.
Publication Date: 2005-11-30 PubMed ID: 16313042DOI: 10.2460/javma.2005.227.1630Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

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This research study conducted longitudinal observations on Standardbred trotters, investigating the rate and evolution of valvular regurgitation—a condition where the heart’s valves do not properly close, causing blood to leak backwards—and its impact on the horses’ racing performance. The study found a higher frequency of regurgitation in horses regularly raced and identified characteristics such as being male and having a bigger left ventricular mass and internal diameter to be common in such horses. However, racing performance did not appear to be affected by this condition.

Research Methodology

In the study, the researchers employed various methods:

  • The researchers selected a sample size of 103 Standardbred trotters for the study.
  • They performed echocardiographic examinations four times at six-month intervals. Echocardiography is a diagnostic test that uses ultrasound waves to produce images of the heart. This allows doctors to monitor how well the heart and its valves are working.
  • They employed two techniques to visualize the heart: Two-dimensional echocardiography and M-mode echocardiography. The former provides a real-time view of the heart that can show the heart’s structure and motion, while the latter obtains time-motion pictures of the heart’s structures.
  • Color Doppler imaging was used to identify and assess the extent of the regurgitant (backwards-flowing) blood at each valve of the horse’s heart.

Findings of the Study

  • The incidence of valvular regurgitation in all the cardiac valves rose substantially over the 18 months of the research. Despite the increase, all cases of regurgitation were classified as mild.
  • The severity of the valvular regurgitation did not progress in any of the horses throughout the course of the study.
  • The study found tricuspid regurgitation—the backflow of blood through the tricuspid valve—was more common in horses that raced regularly.
  • In terms of demographics, male horses and those with larger left ventricular masses and internal diameters during diastole were more likely to be diagnosed with tricuspid regurgitation.
  • However, researchers did not find any correlation between a horse’s racing performance and the presence of valvular regurgitation.

Conclusions of the Study

  • Valvular regurgitation became more common as the horses aged from 2 to 3.5 years. However, the study could not determine whether this was due to maturity or the effect of training.
  • While there was a high prevalence of mild valvular regurgitation at 3.5 years of age, it did not affect the racing performance of the horses in this age group.
  • The potential impact of valvular regurgitation on future performance, or whether the condition will progress, remains unknown.

Cite This Article

APA
Buhl R, Ersbøll AK, Eriksen L, Koch J. (2005). Use of color Doppler echocardiography to assess the development of valvular regurgitation in Standardbred trotters. J Am Vet Med Assoc, 227(10), 1630-1635. https://doi.org/10.2460/javma.2005.227.1630

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 227
Issue: 10
Pages: 1630-1635

Researcher Affiliations

Buhl, Rikke
  • Department of Large Animal Sciences, The Royal Veterinary and Agricultural University, Frederiksberg, Denmark.
Ersbøll, Annette K
    Eriksen, Lis
      Koch, Jørgen

        MeSH Terms

        • Animals
        • Echocardiography, Doppler, Color / methods
        • Echocardiography, Doppler, Color / veterinary
        • Female
        • Heart Valve Diseases / diagnostic imaging
        • Heart Valve Diseases / epidemiology
        • Heart Valve Diseases / veterinary
        • Horse Diseases / diagnostic imaging
        • Horse Diseases / epidemiology
        • Horses
        • Incidence
        • Longitudinal Studies
        • Male
        • Physical Conditioning, Animal / physiology
        • Sex Factors

        Citations

        This article has been cited 5 times.
        1. Marzok M, Kandeel M, Babiker H, Alkhodair KM, Farag A, Ibrahim H, El-Ashker M, Alghuwainem Y, El-Khodery S. M-Mode Echocardiographic Measurements of Interventricular Septum, Left Ventricular Internal Diameter, and Left Ventricular Free-Wall Thickness in Normal Horses-A Meta-Analytical Study. Animals (Basel) 2023 Feb 23;13(5).
          doi: 10.3390/ani13050809pubmed: 36899666google scholar: lookup
        2. Hövener J, Pokar J, Merle R, Gehlen H. Association between Cardiac Auscultation and Echocardiographic Findings in Warmblood Horses. Animals (Basel) 2021 Dec 5;11(12).
          doi: 10.3390/ani11123463pubmed: 34944240google scholar: lookup
        3. Trachsel DS, Giraudet A, Maso D, Hervé G, Hauri DD, Barrey E, Robert C. Relationships between body dimensions, body weight, age, gender, breed and echocardiographic dimensions in young endurance horses. BMC Vet Res 2016 Oct 10;12(1):226.
          doi: 10.1186/s12917-016-0846-xpubmed: 27724944google scholar: lookup
        4. Reef VB, Bonagura J, Buhl R, McGurrin MK, Schwarzwald CC, van Loon G, Young LE. Recommendations for management of equine athletes with cardiovascular abnormalities. J Vet Intern Med 2014 May-Jun;28(3):749-61.
          doi: 10.1111/jvim.12340pubmed: 24628586google scholar: lookup
        5. Folgmann MS, Stock KF, Feige K, Delling U. Clinical findings of candidate stallions presented for licensing at all German Warmblood horse-breeding associations in 2018-2020. Equine Vet J 2025 Nov;57(6):1584-1591.
          doi: 10.1111/evj.14474pubmed: 39838856google scholar: lookup