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Equine veterinary journal2024; doi: 10.1111/evj.14110

Yearling laryngeal function in Thoroughbreds that underwent a laryngoplasty differs from controls.

Abstract: Yearling laryngeal function (YLF) is frequently assessed at the time of sale and the outcomes of these assessments can have significant economic implications. The YLF of horses that subsequently underwent a prosthetic laryngoplasty (PL) is unknown. Objective: We hypothesised horses with YLF ≥grade II.2 would be at increased risk of requiring PL, compared with YLF <grade II.2. Methods: Case-control. Methods: There were 150 PL cases from 2019 to 2021 with an available yearling post-sale videoendoscopic examination and 600 controls. Two observers unaware of the outcome graded YLF using the Havemeyer system. The risk of PL for each YLF grade was calculated using multivariable conditional logistic regression. Results: The proportions of each YLF grade in the control group and PL group, respectively, were grade I: 25.8% and 13.3%, grade II.1: 54.3% and 35.3%, grade II.2: 16.7% and 26%, grade III.1: 3% and 20.7%, grade III.2: 0.2% and 3.3%, grade III.3: 0% and 0.7%, grade IV: 0% and 0.7%. The odds ratio (OR, 95% confidence interval) of requiring PL compared with the referent grade I were: grade II.1: 1.2 (0.7, 2.2, p = 0.5), grade II.2: 3.4 (1.8, 6.1, p < 0.001), grade III.1: 13.8 (6.0, 31.6, p < 0.001), grade III.2: 55.5 (10.3, 299.2, p < 0.001), grade III.3: 2930,000 (398173.7, 21 600,000, p < 0.001), grade IV: 26300,000 (3 420 000, 202 000 000, p < 0.001). Yearling LF ≥grade II.2 had an OR of 4.61 (3.0, 7.1, p < 0.001) compared with <grade II.2; YLF ≥grade III.1 had an OR of 10.7 (5.6, 20.4, p < 0.001) compared with <grade III.1. Conclusions: Lack of performance data to compare the PL and control groups. The control group was not 'disease-free' and may have developed disease and been retired or undergone surgery elsewhere. Conclusions: Three-quarters of the PL group had ≤grade II.2 YLF, demonstrating deterioration in LF post-sale was common. The risk of requiring PL increased from YLF grade II.2 upwards. 背景: 一岁马驹喉功能(YLF)经常在出售时进行评估，这些评估的结果可能具有重要的经济意义。接受喉修补成形术的马驹的YLF以往是未知的。. 目的: 我们假设:一岁马驹喉功能YLF≥II.2级的马驹，需要喉修补成形术PL的风险增加。. 研究设计: 1:4病例对照研究. 方法: 对2019‐2021年的150例PL病例的周岁拍卖内窥镜检查结果，和600例对照。双盲法Havemeyer系统对YLF进行评分。使用多变量条件逻辑回归计算每个YLF等级的PL风险。. 结果: 对照组和PL组各YLF分级所占比例分别为:I级:25.8%和13.3%； II.1级:54.3%和35.3%； II.2级:16.7%和26%；III.1级:1.3%和20.7%；III.2级:0.2%和3.3%；III.3级:0%和0.7%；IV级:0%和0.7%。. 与I级参考相比，需要PL的比值(OR, 95%置信区间)为: II.1级:1.2 (0.7，2.2，p = 0.5)； ii.2级:3.4 (1.8，6.1，p < 0.001)， iii.1级:13.8 (6.0，31.6，p < 0.001)， iii.2级:55.5 (10.3，299.2，p < 0.001)； iii.3级:2930000 (398173.7，21 600 000，p < 0.001)， IV级:26300000 (3 420 000,202 000 000，p < 0.001)。与LF小于II.2级的马驹相比，LF≥II.2级的OR为4.61 (3.0，7.1，p < 0.001)；与 < III.1级相比，YLF≥III.1级的OR为10.7 (5.6，20.4，p < 0.001)。. 主要限制: 缺乏其他性能数据来比较试验组和对照组。对照组并非“无病”，可能也患病，退役或有其他位置手术。. 结论: PL组3 / 4患者的YLF≤II.2级，表明马驹拍卖后喉功能恶化较为常见。需要PL的风险从YLF II.2级上升。.
© 2024 The Author(s). Equine Veterinary Journal published by John Wiley & Sons Ltd on behalf of EVJ Ltd.
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Publication Date: 2024-06-07 PubMed ID: 38847239DOI: 10.1111/evj.14110Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study investigates the laryngeal function in thoroughbreds that underwent a laryngoplasty, finding that these horses tend to show a decline in function post-sale. The research also indicates a correlation between horses with a higher grading of yearling laryngeal function and an increased risk of needing a laryngoplasty.

Objective of the Study

  • The study aimed to identify if there is a link between the Yearling Laryngeal Function (YLF) in horses evaluated at the time of sale and their subsequent need for a prosthetic laryngoplasty (PL).
  • The researchers hypothesized that horses with a YLF of grade II.2 or higher were at a heightened risk of requiring PL, relative to those with a YLF of less than grade II.2.

Methodology

  • The study used a case-control method with 150 PL cases that had a yearling post-sale videoendoscopic examination from 2019 to 2021, compared to 600 controls.
  • The YLF was graded using the Havemeyer system by two observers unaware of the outcome.
  • The risk of PL for each YLF grade was computed using multivariable conditional logistic regression.

Results

  • The researchers found varying proportions of YLF grades in the control and PL groups. Their findings demonstrated an increase in PL risk from the grade of YLF II.2 upwards.
  • Significantly, they found that three-quarters of the PL group had a laryngeal function of less or equal to grade II.2.
  • The odds ratio (OR) for horses with a YLF of grade II.2 was 3.4 times higher compared to horses with a YLF of grade I.

Limitations

  • The study acknowledged a lack of performance data to compare the control group to the PL group.
  • The control group may have developed disease and retired or underwent surgery elsewhere, indicating that the group was not disease-free.

Conclusions

  • Findings showed reasons for concern because a notable proportion of horses deteriorated in their laryngeal function post-sale.
  • Moreover, a higher grade of YLF at sale correlated with an increased chance of requiring a laryngoplasty later in life.

Cite This Article

APA
Hardwick JL, Ahern BJ, Crawford KL, Allen KJ, Franklin SH. (2024). Yearling laryngeal function in Thoroughbreds that underwent a laryngoplasty differs from controls. Equine Vet J. https://doi.org/10.1111/evj.14110

Publication

Equine veterinary journal
ISSN: 2042-3306
NlmUniqueID: 0173320
Country: United States
Language: English

Researcher Affiliations

Hardwick, Josephine L
  • School of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, South Australia, Australia.
  • School of Veterinary Medicine, Murdoch University, Murdoch, Western Australia, Australia.
Ahern, Benjamin J
  • School of Veterinary Science, University of Queensland, Gatton, Queensland, Australia.
Crawford, Kylie L
  • Mater Research Institute, University of Queensland, Brisbane, Queensland, Australia.
Allen, Kate J
  • School of Veterinary Sciences, University of Bristol, Bristol, UK.
Franklin, Samantha H
  • School of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, South Australia, Australia.

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Citations

This article has been cited 1 times.
  1. Hardwick JL, Ahern BJ, Crawford KL, Allen KJ, Anderson BH, Rose KJ, Franklin SH. Yearling laryngeal function grades II.2 and below are not associated with reduced performance. Equine Vet J 2025 Jul;57(4):953-966.
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