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Journal of Zhejiang University. Science. B.
Publisher:
Zhejiang University Press,
Frequency: Monthly
Country: China
Language: English
Author(s):
Zhejiang da xue.
Start Year:2005 -
ISSN:
1673-1581 (Print)
1862-1783 (Electronic)
1673-1581 (Linking)
1862-1783 (Electronic)
1673-1581 (Linking)
Impact Factor
5.1
2022
| NLM ID: | 101236535 |
| (OCoLC): | 57731792 |
| LCCN: | 2005243231 |
| Classification: | W1 JO974HB |
Therapeutic advances in atrial fibrillation based on animal models. Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia among humans, with its incidence increasing significantly with age. Despite the high frequency of AF in clinical practice, its etiology and management remain elusive. To develop effective treatment strategies, it is imperative to comprehend the underlying mechanisms of AF; therefore, the establishment of animal models of AF is vital to explore its pathogenesis. While spontaneous AF is rare in most animal species, several large animal models, particularly those of pigs, dogs, and horses, have proven as invaluable in rec...
Induction of follicular luteinization by equine chorionic gonadotropin in cyclic guinea pigs. The effects of equine chorionic gonadotropin (eCG) on follicular development and ovulation in cyclic guinea pigs were investigated by histological and immunohistochemical analyses. Three groups of guinea pigs (n=12) were administrated subcutaneously with saline, 20 or 50 IU of eCG, respectively, on cyclic Day 12 (Day 1=vaginal openings). Ovaries were collected at 4 and 8 d after administration (6 animals per group each time). The eCG administration induced significant and distinct morphological changes in the ovaries, as it promoted the luteinization of granulosa cells, but not follicular deve...
