PLoS computational biology.
Publisher:
Public Library of Science,
Frequency: Monthly
Country: United States
Language: English
Author(s):
Public Library of Science., International Society for Computational Biology.
Start Year:2005 -
Identifiers
| ISSN: | 1553-734X (Print) 1553-7358 (Electronic) 1553-734X (Linking) |
| NLM ID: | 101238922 |
| (OCoLC): | 57176662 |
| LCCN: | 2004216490 |
| Classification: | W1 PL264M |
Correction: Modelling African horse sickness emergence and transmission in the South African control area using a deterministic metapopulation approach. [This corrects the article DOI: 10.1371/journal.pcbi.1011448.].
Modeling within-host dynamics of influenza virus infection including immune responses. Influenza virus infection remains a public health problem worldwide. The mechanisms underlying viral control during an uncomplicated influenza virus infection are not fully understood. Here, we developed a mathematical model including both innate and adaptive immune responses to study the within-host dynamics of equine influenza virus infection in horses. By comparing modeling predictions with both interferon and viral kinetic data, we examined the relative roles of target cell availability, and innate and adaptive immune responses in controlling the virus. Our results show that the rapid and ...