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Topic:Clinical Findings
Clinical findings in horses encompass a range of observable signs and symptoms identified during veterinary examinations that contribute to diagnosing and managing equine health conditions. These findings can include physical observations, such as changes in behavior, posture, or gait, as well as physiological measurements like heart rate, respiratory rate, and temperature. Diagnostics may also involve laboratory tests, imaging, and other diagnostic procedures to assess organ function and detect abnormalities. Recognizing and interpreting clinical findings are essential components of veterinary practice, aiding in the identification of diseases, monitoring treatment progress, and guiding therapeutic interventions. This page brings together peer-reviewed research studies and scholarly articles that explore the methodologies, interpretations, and implications of clinical findings in the context of equine health care.
Transphyseal vessel involvement in repair of metaphyseal retained cartilage. A foal with retained cartilage in the distal metaphysis of the right and left radii and third metacarpal bones had abnormal physeal vasculature. In areas where cartilage was retained, vessels crossed the physis, and branched at the physeal-metaphyseal junction or at the site of retained cartilage. Vessels appeared to be involved in re-initiation of endochondral ossification and in the repair reponse to the presence of retained cartilage. In areas where the physis was radiographically and histologically normal, no vessels crossed the physis. A function of transphyseal vessels may be as a reserv...
Sexual and in-contact transmission of asinine strain of equine arteritis virus among donkeys. Two in a group of five naturally seropositive donkey stallions were found to shed equine arteritis virus (EAV) in their semen as demonstrated by virus isolation. Direct intramuscular inoculation of sonicated semen from one virus-shedding stallion (S3) caused clinical disease in two donkeys from which virus was recovered and in which seroconversion was detected. Sexual transmission was confirmed in two mares mated to S3 when after a febrile response during which EAV was isolated from huffy coats and nasal and ocular exudates, both mares were found to have seroconverted. In-contact transmission ...
Accuracy of clinicians in predicting site and type of lesion as well as outcome in horses with colic. To assess the ability of clinicians to predict the site and type of lesion as well as outcome in horses with colic. Methods: Prospective case study. Methods: 139 horses admitted for evaluation of signs of colic. Methods: Six interns and residents examined horses with colic and predicted the segment of intestine that was affected, the type of lesion, and whether the horse would survive to discharge. Accuracy of prediction of site and type of lesion and survival prediction was compared between the first and second halves of the year, using chi 2 analysis and 95% confidence intervals on sensitivi...
Diagnostic and forensic toxicology. In most competent veterinary diagnostic laboratories, analytical findings are interpreted by the veterinary toxicologist to determine the significance of the finding in view of historic, clinical, and pathologic findings. A veterinary toxicologist also will provide consultation about possible toxic rule-outs for a case, treatment of affected animals, and prevention of additional cases. Once all of the information is available, a complete summary of the findings can be provided to the client. When the procedures outlined are followed, including a systematic approach to collecting all the eviden...
Abnormalities in oxygenation, coagulation, and fibrinolysis in colonic blood of horses with experimentally induced strangulation obstruction. To measure arterial and venous blood gas, coagulation, and fibrinolysis variables in blood from isolated segments of control and ischemic large colons for the purpose of identifying variables for rapid, indirect assessment of colonic mucosal injury. Methods: Variables were determined at specific intervals during the 4-hour study (3 hours of ischemia and 1 hour of reperfusion). Methods: Seven clinically normal horses between 2 and 15 years old. Methods: Horses underwent laparotomy and occlusion of the lumen and vasculature of the mid-portion of the pelvic flexure of the large colon. During isch...
Association of leptospiral seroreactivity and breed with uveitis and blindness in horses: 372 cases (1986-1993). Recurrent uveitis, a leading cause of blindness in horses, often develops as a sequela to systemic leptospirosis. Over a 7-year period, 63 of 112 (56%) horses with uveitis were seropositive for Leptospira interrogans serovar pomona, but only 23 of 260 (9%) horses without uveitis were seropositive. Odds-ratio analysis revealed that seropositive horses were 13.2 times more likely to have uveitis than were seronegative horses. Of the 63 seropositive horses with uveitis, 59% developed blindness, compared with only 24% in the 49 seronegative horses with uveitis that lost vision in 1 or both eyes du...
Near infrared spectroscopy of pedal haemodynamics and oxygenation in normal and laminitic horses. The present study applies near infrared spectroscopy (NIRS) to the haemodynamics of the pedal circulation in normal and laminitic horses. NIRS is a noninvasive technique which uses changes in light absorption at 4 wavelengths to provide information on the changes in cytochrome aa3 (cyt aa3) reduction-oxidation (redox) status, and changes in the tissue concentration of oxyhaemoglobin (O2Hb), deoxyhaemoglobin (HHb) and therefore total haemoglobin (tHb). Other studies have shown NIRS to be sensitive to changes in tissue oxygenation and perfusion in human cerebral and limb circulation. In this stu...
Gunshot injuries in horses: 22 cases (1971-1993). Twenty-two horses were examined because of firearm injuries. Nine had been shot with .22-caliber bullets, 2 with BB pellets, 6 with buckshot, 1 with a .35-caliber bullet, and 1 with an airgun pellet. Injury was confined to the skin or skeletal muscles in 8 horses. Of these, 7 returned to their previous use. In 14 horses, injuries to additional structures were incurred, including the sinus and pharynx (n = 2), mandible (n = 1), tooth (n = 1), aorta (n = 1), eye (n = 3), tibia (n = 1), gastrointestinal tract (n = 3), joint (n = 1), and trachea (n = 1). The 3 horses that had only eye injuries wer...
Treatment and outcome of chronic tenosynovitis in three horses. Three horses were presented for treatment of chronic infections of the digital flexor tendon sheath. Clinical signs included severe lameness, and heat, pain and swelling of the digital flexor tendon sheath. The horses were treated with surgical lavage of the tendon sheath, systemic and local antibiotics, and analgesics. In each case, resolution of the lameness occurred over weeks to months. Only one horse returned to athletic activity, while the other two became comfortable at pasture. Response to treatment in cases of chronic tenosynovitis may not be as rapid or complete as that reported for ...
Equine viral arteritis with abortions: serological and virological evidence in Germany. An outbreak of clinical disease with abortions, suspected to be equine viral arteritis in Germany was examined serologically and virologically. Three of five animals tested seroconverted to EAV, and EAV was isolated from an aborted fetus. In view of the significant increase in seropositive horses, the need for control measures is emphasized.
Necropsy survey of metacarpal fusion in the horse. Paired metacarpi obtained at necropsy from 100 horses ranging in age from term fetus to 35 years were examined to estimate the prevalence and sites of metacarpal fusion. Metacarpal fusion was seen in 192 of 200 metacarpi, and 78% of all horses 2 years or older had 2 or more fusions. Fusion of the second metacarpal bone to the third metacarpal bone was significantly (P < 0.001) more common than was fusion of the fourth to the third metacarpal bone. Fusions appeared for the most part in pairs and were bilaterally symmetric. Rooney-Prickett type-A carpometacarpal joint configurations (in which...
Physiological responses to the endurance test of a 3-day-event during hot and cool weather. Physiological data were collected during two 3-day-event competitions: one (H) held in hot and the other (CL) in cool conditions. During H, ambient temperature and relative humidity were 2.5 degrees C-35 degrees C and 74-36% respectively, while during CL, ambient temperature and relative humidity were 7.8 degrees C-8.3 degrees C and 46%-41%, respectively. Rectal temperature, heart and respiratory rates were recorded on arrival at the event, at the end of Phase C and 6 min later, at the end of Phase D and for 30 min at 10 min intervals after each horse finished Phase D (Recovery Period). Becaus...
Equine pulmonary disease: a case control study of 300 referred cases. Part 4: Treatments and re-examination findings. One-hundred and forty-seven of 270 (54.4%) horses suffering from pulmonary disorders were given at least one re-examination including, clinical, bronchoscopic, pulmonary function and cytological examinations after treatment and a further 83 of these horses (30.7%) had their clinical progress assessed by verbal or written reports. These examinations and progress reports showed high levels of partial or total recovery for most pulmonary disease categories, including chronic obstructive pulmonary disease, infectious, S. zooepidemicus and undifferentiated pulmonary disease and lungworm infection g...
Equine pulmonary disease: a case control study of 300 referred cases. Part 2: Details of animals and of historical and clinical findings. Examination of historical and clinical details of 270 adult horses suffering from a variety of mainly chronic pulmonary diseases showed that the chronic obstructive pulmonary disease (COPD) group (median age 9 years) were the oldest, and that the COPD, chronic idiopathic hypoxaemia and exercise induced pulmonary haemorrhage (EIPH) groups had the longest duration of disease (median durations 7, 12 and 9 months, respectively) with a median disease duration of 2 months for the remaining horses. A history of antecedent respiratory infection was present in 24.3% of all horses. Six out of 12 horses ...
Complications of celiotomy incisions in horses. Complications of celiotomy incisions were evaluated retrospectively in 274 horses that survived at least 1 month after surgery, or died or were euthanatized within 1 month of surgery, as a direct result of these complications. Horses were divided into four groups; group A, a ventral median celiotomy for intestinal disease; group B, ventral median celiotomy for nonintestinal disease; group C, repair of an umbilical hernia; and group D, celiotomy in a region other than the midline. Specific incisional complications were peri-incisional edema, drainage, incisional abscess, suture sinus, and dehis...
Clinical observations made in nonheat acclimated horses performing treadmill exercise in cool (20 degrees C/40%RH), hot, dry (30 degrees C/40%RH) or hot, humid (30 degrees C/80%RH) conditions. Four horses (H, J, N and M) undertook a treadmill competition exercise test (CET), designed to simulate the physiological and metabolic stresses of the Speed and Endurance phase of a 3-day-event, under 3 different environmental conditions: 20 degrees C/40% relative humidity (RH) (cool, dry [CD]: 2 sessions); 30 degrees C/40%RH (hot, dry [HD]) and 30 degrees C/80%RH (hot, humid [HH]) (Marlin et al. 1995). A number of subjective clinical observations were made at designated time points throughout the exercise test and initial recovery period including buccal mucous membrane colouration, capillar...
Intestinal fibrosis and vascular remodeling in ten horses and two ponies. No abstract available
[Sonographic diagnosis (B-mode technique) for the eyes in horses. 1. Methods and normal findings]. In this presentation, normal sonoanatomy of the horse eye will be introduced and biometrical data of 30 healthy eyes along optical axis will be presented. We used the ultrasound system Philips Diagnost R 1200 in connection with a 5 MHz linear transducer. With this equipment it is possible to visualize and measure at the unaltered eye the cornea, the anterior chamber of the eye, ciliary body, iris, lens, vitreous body, wall of the posterior globe (retina, choroid, sclera) and retrobulbar structures (optical nerve, retrobulbar muscles, orbital fat pad, bony orbita). The echographical examination...
Comparison of the effects of low-molecular-weight and unfractioned heparin in horses. Thirty healthy male horses were allotted to 3 groups and treated blindly during 4 days. Group-1 horses received unfractioned calcium heparin (100 IU/kg of body weight, SC, q 12 h). Group-2 horses received a single dose of a low-molecular-weight heparin (50 anti-Xa IU/kg, SC) every morning, and a similar volume of saline solution every evening. Group-3 horses received the vehicle (saline solution), SC, every 12 hours. Citrated and EDTA-anticoagulated blood samples were collected before starting the medication (T-0) and once daily 3 hours after each morning injection (T-3, T-27, T-51, and T-75)....
Comparison of bronchoalveolar lavage findings and measurements of gas exchange during exercise in horses with poor racing performance. Twenty-four Thoroughbred and twelve Standardbred racehorses aged between 2 and 6 years, presented for reported poor racing performance, underwent clinical exercise testing. During the last 10 s of exercise at each speed throughout an incremental speed exercise test on a treadmill inclined at a 10% slope, samples of arterial blood and expired gases were collected. Maximum oxygen uptake and the partial pressures of oxygen and carbon dioxide in arterial blood were determined. These values were compared between the two breeds of horses and also with reference to cytological findings of bronchoalve...
Ultrasonographic cross-sectional area and mean echogenicity of the superficial and deep digital flexor tendons in 50 trained thoroughbred racehorses. Fifty Thoroughbred horses were examined. All horses had been in race training for a minimum of 4 months before examination and had worked at racing speed; 24 horses had raced. All horses were clinically sound at the time of examination. Ultrasonography was performed, using a 7.5-MHz transducer with built-in fluid offset. Videotaped images of the palmar soft tissue structures were obtained at 4, 8, 12, 16, 20 and 24 cm distal to the base of the accessory carpal bone (DACB). Images were digitized, and each image was calibrated. Values for cross-sectional area (CSA) and mean echogenicity (ME) wer...
Intracranial pressure and cerebral perfusion pressure in clinically normal equine neonates. Intracranial pressure (ICP) and cerebral perfusion pressure (CPP) were determined in 8 clinically normal neonatal foals. After the foals oriented themselves and nursed the mares, they were sedated as necessary, and local anesthesia was provided for making the skin incisions. Using a technique similar to that used in human beings, an indwelling subdural catheter was placed to measure ICP. Carotid artery catheterization was used to measure arterial blood pressure. Cerebral perfusion pressure was calculated as the difference between mean arterial blood pressure and ICP. Intracranial pressure and ...
[Differentiated prognosis in the colicky horse]. In a retrospective study on 271 horses with colic the prediction about the outcome of the disease was made by a discriminating analysis. The best combination of quantitative prognostic parameters was capillary refill time, hematocrit, lactate and anion gap, with 90% correct predictions. In comparison with individually prognostic parameters, the combined prognosis constantly reached a higher percentage of correct predictions, the exact value resulting in 89%. Moreover, survival was better predictable than death.
Suture sinus formation following closure of ventral midline incisions with polypropylene in three horses. Suture sinuses formed in 3 horses following closure of ventral midline incisions with size-2 polypropylene. Suture sinuses healed after the suture material was removed. Suture sinus formation following closure with polypropylene may be related to the suture material's mechanical, rather than its chemical, properties. If polypropylene is used to close the linea alba in horses, the amount of tissue incorporated in the suture loops, suture tension, and knot volume should be minimized to decrease the risk of suture sinus formation.
Comparison of polysulphated glycosaminoglycan and sodium hyaluronate with placebo in treatment of traumatic arthritis in horses. A randomised double blind and placebo controlled clinical study was carried out. Standardbred trotters (n=77), age 3-4 years) with moderate to severe lameness were grouped according to number of affected joints and, within each group, were randomised for treatment with polysulphated glycosaminoglycan (PSGAG), sodium hyaluronate (SH) or placebo for 3 weeks. The horses were inspected weekly with a final examination 2-4 weeks after the end of treatment. Mean initial lameness score was significantly reduced during treatment and at the last examination in all 3 groups (P<0.01). Additionally, the...
