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Topic:Clinical Findings

Clinical findings in horses encompass a range of observable signs and symptoms identified during veterinary examinations that contribute to diagnosing and managing equine health conditions. These findings can include physical observations, such as changes in behavior, posture, or gait, as well as physiological measurements like heart rate, respiratory rate, and temperature. Diagnostics may also involve laboratory tests, imaging, and other diagnostic procedures to assess organ function and detect abnormalities. Recognizing and interpreting clinical findings are essential components of veterinary practice, aiding in the identification of diseases, monitoring treatment progress, and guiding therapeutic interventions. This page brings together peer-reviewed research studies and scholarly articles that explore the methodologies, interpretations, and implications of clinical findings in the context of equine health care.
Referring equine veterinarians’ expectations of equine veterinary specialists and referral centers.
Journal of the American Veterinary Medical Association    July 31, 2018   Volume 253, Issue 4 479-489 doi: 10.2460/javma.253.4.479
Best C, Coe JB, Hewson J, Meehan M, Kelton D, Black B.OBJECTIVE To explore referring equine veterinarians' expectations of equine veterinary referral centers and specialists. DESIGN Qualitative, focus group interview-based study. SAMPLE 6 focus groups comprised of equine practitioners with experience in referral of clients and patients to equine specialists or referral centers (48 referring veterinarians [rDVMs]). PROCEDURES Focus group sessions were conducted independently and followed a standardized discussion guide consisting of open-ended questions and follow-up probes. Discussions were recorded, and thematic analysis was performed on the con...
Use of crown height of the maxillary first molar tooth to approximate the age of horses.
American journal of veterinary research    July 31, 2018   Volume 79, Issue 8 867-873 doi: 10.2460/ajvr.79.8.867
Carmalt JL, Henderson KV, Rawlinson JE, Waldner CL.OBJECTIVE To identify whether age, sex, or breed is associated with crown height of the left and right maxillary first molar tooth (M1) measured on CT images, to develop a mathematical model to determine age of horses by use of M1 crown height, and to determine the correlation between M1 crown height measured on radiographic and CT images. SAMPLE CT (n = 735) and radiographic images (35) of the heads of horses. PROCEDURES Crown height of left and right M1 was digitally measured on axial CT views. Height was measured on a lateral radiographic image when available. Linear regression analysis was...
Heart valve pathology in regularly slaughtered horses.
Veterinaria italiana    July 19, 2018   Volume 54, Issue 2 165-168 doi: 10.12834/VetIt.1394.7616.1
Passantino G, Scaglione FE, Zizzo N, Leone R, Guarda F.In this study we examined macroscopic and microscopic lesions in the mitral valves of 50 regularly slaughtered horses in Italy. Macroscopically the results were minor. Microscopic lesions to the valve were found in both young and elderly subjects, confirming that there is no correlation between age and onset of lesions. We set out to evaluate whether the lesions correspond to valve disorder during the life of the animal.
Exhaled breath condensate hydrogen peroxide, pH and leukotriene B4 are associated with lower airway inflammation and airway cytology in the horse.
Equine veterinary journal    July 19, 2018   Volume 51, Issue 1 24-32 doi: 10.1111/evj.12979
du Preez S, Raidal SL, Doran GS, Prescott M, Hughes KJ.Exhaled breath condensate (EBC) analysis is a noninvasive method to assess the lower respiratory tract. In human subjects, EBC hydrogen peroxide (H O ), pH and leukotriene B (LTB ) are useful for detection and monitoring of inflammatory lung diseases, including asthma. Objective: To determine associations between EBC biomarkers and cytological and endoscopic definitions of lower airway inflammation (LAI) while controlling for sampling and environmental variables. Methods: Prospective, cross-sectional study. Methods: Clinical, endoscopic and airway cytological findings from 47 horses were compa...
Cardiac/Cardiovascular Conditions Affecting Sport Horses.
The Veterinary clinics of North America. Equine practice    July 17, 2018   Volume 34, Issue 2 409-425 doi: 10.1016/j.cveq.2018.04.001
Chope KB.Cardiac murmurs are not uncommonly detected in the equine athlete. Although most are benign in nature, differentiation and quantification of murmurs due to valvular regurgitation are important for prognosis and recommendations. Arrhythmias can be associated with structural disease or occur independently and may range in severity from minimal clinical effect to poor performance to presenting a safety risk to rider and horse. This article discusses commonly encountered cardiac conditions in the sport horse. Physical examination, diagnostic approach, valvular disease, and arrhythmias with an impa...
Lameness Evaluation of the Athletic Horse.
The Veterinary clinics of North America. Equine practice    July 17, 2018   Volume 34, Issue 2 181-191 doi: 10.1016/j.cveq.2018.04.013
Davidson EJ.Lameness examination is commonly performed in the athletic horse. A skilled lameness diagnostician must have keen clinical and observational skills. Evaluation starts with a detailed history and thorough physical examination. Next, gait evaluation in the moving horse is performed. Lame horses have asymmetrical body movement due to unconscious shift of body weight. Recognition of the resultant head nod and pelvic hike is the basis for lameness diagnosis. Lameness identification is enhanced by circling, limb flexions, and riding. Most lame horses do not exhibit pathognomonic gait characteristics...
What is your diagnosis? Bladder mass in a mare.
Veterinary clinical pathology    July 16, 2018   Volume 47, Issue 4 665-666 doi: 10.1111/vcp.12637
Fielder S, Breshears M.No abstract available
Prevalence of complications associated with use of the Henderson equine castrating instrument.
Equine veterinary journal    July 12, 2018   Volume 51, Issue 2 163-166 doi: 10.1111/evj.12982
Hinton S, Schroeder O, Aceto HW, Berkowitz S, Levine D.Castration is one of the most common surgical procedures performed in the horse. Complication rate and types of complications associated with use of the Henderson equine castrating instrument have not been determined. Objective: To determine the complication rate and type of complications encountered when using the Henderson equine castrating instrument in equine ambulatory practice. Methods: Retrospective case series. Methods: Medical records of horses undergoing routine castration using the Henderson drill were identified and evaluated for the occurrence of complications. The relationship be...
Current dorsal myelographic column and dural diameter reduction rules do not apply at the cervicothoracic junction in horses. Estell K, Spriet M, Phillips KL, Aleman M, Finno CJ.Previously published myelographic studies do not report findings at the junction between the seventh cervical (C7) and first thoracic vertebrae (T1). Modern digital radiographic equipment allows improved visualization of C7-T1. Based on clinical experience, we hypothesized that 50% reduction of the dorsal myelographic column or 20% reduction of the dural diameter, criteria commonly used as a supportive finding for spinal cord compression in the cervical vertebral column, do not apply at C7-T1. A myelographic study was performed on 12 healthy, neurologically normal horses. Our hypothesis was co...
Equine pericardium-covered stenting in post-traumatic pseudoaneurysm of cavernous internal carotid artery.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences    July 5, 2018   Volume 24, Issue 6 635-638 doi: 10.1177/1591019918785150
Gonzalez-Cantero JL, Del Valle Diéguez M, Monteserín Matesanz C, Saura Lorente J, Villoria Medina F, Fortea Gil F, Castro Reyes E.We report a case of traumatic intracranial carotid artery pseudoaneurysm treated with an equine pericardium-covered stent. The patient was admitted to the Emergency Department after sustaining severe polytrauma in a motor vehicle accident. A cavernous carotid pseudoaneurysm was detected after an episode of massive epistaxis that required emergent nasal packing. Treatment with parent vessel sacrifice was ruled out after an unfavourable balloon test occlusion. We opted for an equine pericardium-covered stent as a means to immediately seal the wall defect in the setting of massive bleeding second...
Cortisol, progesterone, 17αOHprogesterone, and pregnenolone in foals born from mare’s hormone-treated for experimentally induced ascending placentitis.
Theriogenology    June 30, 2018   Volume 123 139-144 doi: 10.1016/j.theriogenology.2018.06.024
Müller V, Curcio BR, Toribio RE, Feijó LS, Borba LA, Canisso IF, Nogueira CEW.This study aimed to evaluate steroid hormones in foals born from mares treated for ascending placentitis with different combinations of trimethoprim-sulfamethoxazole (TMS), flunixin meglumine (FM), long-acting altrenogest (ALT) and estradiol cypionate (ECP) for ten consecutive days, starting two days after experimental induction of placentitis with Streptococcus zooepidemicus. Fourty-six pregnant mares and respective foals were assigned as healthy group (Control, n = 8) or treated groups as follows: TMS+FM (n = 8), TMS+FM+ALT (n = 8), TMS+FM+ALT+ECP (n = 6), TMS+FM+ECP (n = 6) and no...
To Scan or Not to Scan: Horses and Zebras.
The primary care companion for CNS disorders    June 28, 2018   Volume 20, Issue 3 18alz02292 doi: 10.4088/PCC.18alz02292
Weidman DA, Burke AD, Eschbacher JM, Copeland JN, Grigaitis-Reyes M, Burke WJ.No abstract available
Epidemiology of race-day distal limb fracture in flat racing Thoroughbreds in Great Britain (2000-2013).
Equine veterinary journal    June 28, 2018   Volume 51, Issue 1 83-89 doi: 10.1111/evj.12968
Rosanowski SM, Chang YM, Stirk AJ, Verheyen KLP.A key focus of the racing industry is to minimise the number of race-day distal limb fractures although no studies have identified risk factors for both fatal and non-fatal distal limb fractures. Objective: To determine risk factors for race-day distal limb fractures experienced by Thoroughbred racehorses participating in flat racing in Great Britain (GB). Methods: Retrospective cohort. Methods: Information was collected from all flat racing starts occurring on GB racecourses between 2000 and 2013, including horse, race, course, trainer and jockey data for each horse start and race-day injury ...
Comparison of conventional radiography and computed tomography as aids in the diagnosis of osteomyelitis in 11 foals.
Australian veterinary journal    June 27, 2018   Volume 96, Issue 7 257-261 doi: 10.1111/avj.12710
Lean NE, Perkins NR, Ahern BJ.Conventional radiography is currently the most common imaging modality used by veterinarians investigating foals with suspected osteomyelitis. Emerging evidence in adult horses and humans suggests computed tomography (CT) is a superior modality for evaluation of osseous changes in general. This study aimed to evaluate the potential benefits of CT versus conventional radiography in cases of osteomyelitis in foals. Methods: Cases of osteomyelitis in foals under 6 months of age admitted over a 6-year period at a single referral hospital that had both CT and conventional radiography images were ...
Evaluation of Histogel- and Gelfoam-embedded bronchoalveolar lavage and transtracheal wash fluids compared with cytocentrifuged and sediment smear preparations.
Veterinary clinical pathology    June 27, 2018   Volume 47, Issue 3 471-476 doi: 10.1111/vcp.12624
Haysom LZ, Lee-Fowler TM, Spangler EA.Storage and temperature significantly impact bronchoalveolar lavage fluid (BALF) analysis, and shipment of samples to diagnostic laboratories is often necessary. Alternative sample preparation methods could limit storage and temperature effects. Objective: This study aimed to determine if airway wash samples that were fixed in formalin after being embedded in Histogel or Gelfoam gave comparable results to fresh cytocentrifuged or sediment smear preparations for the evaluation of cell morphology. Methods: Eleven bronchoalveolar lavage and 3 transtracheal wash fluids were available, including 8 ...
The prevalence of Dermatophilus congolensis in horses with pastern dermatitis using PCR to diagnose infection in a population of horses in southern USA.
Veterinary dermatology    June 21, 2018   Volume 29, Issue 5 435-e144 doi: 10.1111/vde.12659
Aufox EE, Frank LA, May ER, Kania SA.Dermatophilus congolensis is a facultative anaerobic actinomycete that causes papular to exudative dermatitis with crusting in horses. This organism is frequently implicated as a cause of pastern dermatitis, but few data are available validating the organism's association with this disease. Objective: The aim of this study was to evaluate if D. congolensis is associated with pastern dermatitis in horses utilizing RT-qPCR. Methods: Fifteen client-owned horses diagnosed with pastern dermatitis and eight client-owned unaffected control horses were utilized for this study. Methods: A cross-sectio...
Association between hyperinsulinaemia and laminitis severity at the time of pituitary pars intermedia dysfunction diagnosis.
Equine veterinary journal    June 20, 2018   Volume 51, Issue 1 52-56 doi: 10.1111/evj.12963
Tadros EM, Fowlie JG, Refsal KR, Marteniuk J, Schott HC.Hyperinsulinaemia is the suspected component of insulin dysregulation having the strongest association with laminitis and occurs variably in equids with pituitary pars intermedia dysfunction (PPID). Objective: We hypothesised that magnitude of hyperinsulinaemia correlates with laminitis severity in PPID-affected equids. Furthermore, we hypothesised that owners can be unaware of chronic endocrinopathic laminitis. Methods: Cross-sectional study. Methods: Serum insulin concentrations, owner-reported laminitis history and radiographic evidence of laminitis were determined in 38 client-owned horses...
Clinical features and outcome in horses with severe large intestinal thickening diagnosed with transabdominal ultrasonography: 25 cases (2003-2010).
Journal of the American Veterinary Medical Association    June 19, 2018   Volume 253, Issue 1 108-116 doi: 10.2460/javma.253.1.108
Biscoe EW, Whitcomb MB, Vaughan B, Dechant JE, Magdesian KG.OBJECTIVE To describe clinical features and outcome of horses with severe large intestinal thickening diagnosed with transabdominal ultrasonography. Methods: Retrospective case series. ANIMALS 25 horses. PROCEDURES Medical records of horses that underwent transabdominal ultrasonography between 2003 and 2010 were reviewed. Horses were included if the wall of the large intestine was ≥ 9 mm thick in any of 6 abdominal zones. RESULTS Median age was 13 years (range, 3 to 28 years). Horses were initially examined because of colic, diarrhea, inappetence, weight loss, lethargy, fever, or hematuria. ...
Equine duodenitis-proximal jejunitis: A review.
The Canadian veterinary journal = La revue veterinaire canadienne    June 16, 2018   Volume 59, Issue 5 510-517 
Arroyo LG, Gomez DE, Martins C.Duodenitis-proximal jejunitis (DPJ) is an inflammatory process of the proximal part of the small intestine and occurs sporadically in horses. It is clinically characterized by an acute onset of ileus and nasogastric reflux leading to systemic signs of toxemia. This review discusses the definition of the disease, potential etiologic agents, clinical findings, epidemiological features, histopathologic and clinico-pathological findings, and medical management of this condition. spp., mycotoxins, and have all been associated with the disease but there is limited supporting evidence for any agen...
Pituitary Pars Intermedia Dysfunction (Equine Cushing’s Disease) in Nondomestic Equids at Marwell Wildlife: A Case Series. One Chapman’s Zebra (Equus Quagga chapmani) and Five Przewalski’s Horses (Equus Ferus przewalskii).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians    June 15, 2018   Volume 49, Issue 2 404-411 doi: 10.1638/2017-0149.1
Shotton JCR, Justice WSM, Salguero FJ, Stevens A, Bacci B.  Pituitary pars intermedia dysfunction (PPID), also known as equine Cushing's disease, is widely reported in middle-aged to older domestic equids but to date reported in only one nondomestic equid, the onager ( Equus hemionus onager). This case series reports clinical, hematological, and pathological findings consistent with PPID in two further equid species: one Chapman's zebra ( Equus quagga chapmani) and five Przewalski's horses ( Equus ferus przewalskii). The case series reports basal adrenocorticotropic hormone (ACTH) testing as a method to diagnose and monitor PPID in zoological equid...
Equine foetal gender determination in mid- to late gestational mares: A practical inquiry.
Reproduction in domestic animals = Zuchthygiene    June 12, 2018   Volume 53, Issue 5 1027-1032 doi: 10.1111/rda.13211
Van de Velde M, Roels K, Ververs C, Gerits I, Govaere J.In recent years, the interest in equine foetal gender determination (FGD) during gestation increased remarkably. Ultrasonographic FGD can be performed in two different periods during gestation. The earliest examination can take place at a gestational age of 60-70 days, whereby the genital tubercle is used to differentiate between male and female foeti. The time window of the second approach is wider (120-210 days), and there are more characteristics to take into consideration. In this article, the feasibility and accuracy of ultrasonographic FGD in mid- to late gestation are evaluated. One h...
Evaluation of Systemic and Local Inflammatory Parameters and Manifestations of Pain in an Equine Experimental Wound Model.
Journal of equine veterinary science    June 4, 2018   Volume 68 81-87 doi: 10.1016/j.jevs.2018.05.219
Bundgaard L, Sørensen MA, Nilsson T, Salling E, Jacobsen S.In the last decades, a well-established equine wound model has been used to study fibroproliferative wound healing disorders. The aim of this study was to characterize the degree of discomfort of wounding and sampling in an equine excisional wound model by evaluating systemic and local inflammatory responses and signs of pain. A total of 12 cutaneous wounds, three on each shoulder and each metatarsus, were created in a standing surgical procedure. Wounds were biopsied on days 2, 4, 7, 14, 21, and 28 after surgery. Clinical parameters (rectal temperature, heart rate, respiratory frequency) and ...
Equine pituitary pars intermedia dysfunction: current understanding and recommendations from the Australian and New Zealand Equine Endocrine Group.
Australian veterinary journal    June 3, 2018   Volume 96, Issue 7 233-242 doi: 10.1111/avj.12716
Secombe CJ, Bailey SR, de Laat MA, Hughes KJ, Stewart AJ, Sonis JM, Tan R.The purpose of this article is to provide a review of the current knowledge and opinions about the epidemiology, clinical findings (including sequelae), diagnosis, treatment and monitoring of equine pituitary pars intermedia dysfunction, particularly in the Australian context. This information and the recommendations provided will assist practitioners in making informed decisions regarding the diagnosis and management of this disorder.
The Efficacy of Intermittent Long-term Bell Boot Application for the Correction of Muscle Asymmetry in Equine Subjects.
Journal of equine veterinary science    May 26, 2018   Volume 68 73-80 doi: 10.1016/j.jevs.2018.05.214
Jensen AM, Ahmed W, Elbrønd VS, Harrison AP.It has been proposed that manipulating proprioceptive signals of the equine distal limb as part of a rehabilitation process in cases of musculoskeletal pain or neurologic deficits can be used to correct postural control and restore normal motor programs. This trial has examined the effect of treatment with a light-weight and loose-fitting bell boot (82 g) on an imbalance of muscle gluteus superficialis function in horses as measured using acoustic myography (AMG). Eight horses were trained over a 60-minute period every 3 days for 6 weeks, a protocol based on preliminary findings. Acoustic my...
Upper Airway Conditions Affecting the Equine Athlete.
The Veterinary clinics of North America. Equine practice    May 21, 2018   Volume 34, Issue 2 427-441 doi: 10.1016/j.cveq.2018.04.008
Parente EJ.Many abnormalities of the upper airway that can inhibit performance are determined on a critical resting endoscopic evaluation. Some dynamic abnormalities can only be seen during an exercising endoscopic evaluation, which should be performed whenever the history of abnormal noise or performance limitations is not completely consistent with the resting endoscopic findings. Head and neck position may play a critical role in the evaluation process and the exact position during performance should be reproduced during the clinical examination to definitively define the abnormality. Treatments and p...
Mineralization can be an incidental ultrasonographic finding in equine tendons and ligaments. O'Brien EJO, Smith RKW.Tendon/ligament mineralization is recognized in horses but information regarding its clinical significance is limited. The aims of this observational study were to report the structures most commonly affected by ultrasonographically detectable mineralization and, for these, determine frequency of diagnosis and key clinical features. Cases presented at our hospital in April 1999-April 2013 and September 2014-November 2015 were included: a total of 27 horses (22 retrospective, five prospective). Mineralizations were most common in deep digital flexor tendons (10) and suspensory ligament branches...
Effects of a P-class CpG-ODN administered by intramuscular injection on plasma cytokines and on white blood cells of healthy horses.
Veterinary immunology and immunopathology    May 16, 2018   Volume 201 57-61 doi: 10.1016/j.vetimm.2018.05.004
Tosi I, Bureau F, Farnir F, Denoix JM, Lekeux P, Art T.Cytosine-phosphate-guanosine (CpG-ODN) has been described as a potent immunostimulatory agent in different species. No study reported the effect of a P-class CpG when administered systemically in healthy horses. The aim of this study was to evaluate the tolerance and the effect of an intramuscularly administered P-class CpG-ODN on hematology and on plasma cytokines (IFN-α, IL-10, TNF-α, IFN-γ) in 8 healthy horses. Intra-muscular CpG-ODN or placebo (PBS) was administered twice at a 7 days-interval. Groups were inversed after 2 months of washout period. A physical examination, complete bloo...
Novel findings from a beta coronavirus outbreak on an American Miniature Horse breeding farm in upstate New York.
Equine veterinary education    May 16, 2018   Volume 32, Issue 3 150-154 doi: 10.1111/eve.12938
Goodrich EL, Mittel LD, Glaser A, Ness SL, Radcliffe RM, Divers TJ.This case report describes an outbreak and novel findings associated with a beta coronavirus (BCoV) infection that occurred on an American Miniature Horse (AMH) breeding farm in upstate New York, in January and February of 2013. Twenty-nine AMH and one donkey were present on the farm when the outbreak occurred. One 10-year-old Quarter Horse mare, stabled at a separate location and owned by an employee of the farm, also tested positive. A polymerase chain reaction (PCR) assay for the detection of BCoV was performed at the Animal Health Diagnostic Center (AHDC) at Cornell on all faecal samples. ...
Ultrasonographic variations are present in the distal sesamoidean impar ligament of clinically sound horses. MacDonald JL, Richter RA, Wimer CL.Ultrasonography is an established diagnostic test for evaluating horses with foot pain due to suspected podotrochlear apparatus pathology. However, variations from the previously reported normal appearance of the distal sesamoidean impar ligament have not always coincided with lameness. The objective of this prospective, cross-sectional, descriptive study was to characterize variations in the ultrasonographic appearance of the distal sesamoidean impar ligament in sound horses using the transcuneal approach. Transcuneal ultrasonography of the distal sesamoidean impar ligament was performed on s...
Cardiorespiratory effects of a 7° reverse Trendelenburg position in anaesthetized horses: a randomized clinical trial.
Veterinary anaesthesia and analgesia    May 9, 2018   Volume 45, Issue 5 648-657 doi: 10.1016/j.vaa.2018.03.011
Schauvliege S, Binetti A, Duchateau L, van Dijk JJ, Gasthuys F.To evaluate the cardiorespiratory effects of a 7° reverse Trendelenburg position (RTP) in anaesthetized horses. Methods: Randomized, non-blinded clinical trial. Methods: A total of 125 horses undergoing elective surgery in dorsal recumbency. Methods: Horses were allocated to one of three weight classes and assigned to be positioned either on a horizontal table or on a table in 7° RTP, according to a randomized block design. In all horses, anaesthesia was maintained with isoflurane in oxygen and a constant rate infusion of romifidine. All horses were mechanically ventilated throughout anaesth...
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