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Topic:Clinical Findings

Clinical findings in horses encompass a range of observable signs and symptoms identified during veterinary examinations that contribute to diagnosing and managing equine health conditions. These findings can include physical observations, such as changes in behavior, posture, or gait, as well as physiological measurements like heart rate, respiratory rate, and temperature. Diagnostics may also involve laboratory tests, imaging, and other diagnostic procedures to assess organ function and detect abnormalities. Recognizing and interpreting clinical findings are essential components of veterinary practice, aiding in the identification of diseases, monitoring treatment progress, and guiding therapeutic interventions. This page brings together peer-reviewed research studies and scholarly articles that explore the methodologies, interpretations, and implications of clinical findings in the context of equine health care.
Descriptive results from a longitudinal study of airway inflammation in British National Hunt racehorses.
Equine veterinary journal    March 15, 2011   Volume 43, Issue 6 750-755 doi: 10.1111/j.2042-3306.2010.00338.x
Cardwell JM, Wood JL, Smith KC, Newton JR.Rates of airway inflammation in young racehorses decrease with time but it is not clear whether this is associated with increasing age or time exposed to the training environment. The structure of the British National Hunt (NH) population allowed closer examination of this relationship. Objective: To compare rates of inflammatory airway disease diagnosed by tracheal sampling (trIAD), and its components, in NH racehorses by age and training history and with published rates in young racehorses. Methods: A prospective, longitudinal study was conducted on 5 NH yards over 2 years. Period sample pre...
Equine pituitary pars intermedia dysfunction.
The Veterinary clinics of North America. Equine practice    March 12, 2011   Volume 27, Issue 1 93-113 doi: 10.1016/j.cveq.2010.12.007
McFarlane D.Equine pituitary pars intermedia dysfunction (PPID), also known as equine Cushing's syndrome, is a widely recognized disease of aged horses. Over the past two decades, the aged horse population has expanded significantly and in addition, client awareness of PPID has increased. As a result, there has been an increase in both diagnostic testing and treatment of the disease. This review focuses on the pathophysiology and clinical syndrome, as well as advances in diagnostic testing and treatment of PPID, with an emphasis on those findings that are new since the excellent comprehensive review by Sc...
Partial ostectomy of the dens to correct atlantoaxial subluxation in a pony.
Veterinary surgery : VS    March 11, 2011   Volume 40, Issue 5 596-600 doi: 10.1111/j.1532-950X.2011.00816.x
Cillán-Garcia E, Taylor SE, Townsend N, Licka T.To report a surgical technique that allows decompression and anatomic re-alignment for management of subluxation of the atlantoaxial articulation. Methods: Clinical report. Methods: Four-year-old Welsh Section B pony gelding. Methods: Attempts at closed reduction of subluxation of the atlantoaxial articulation under general anesthesia were unsuccessful, so a ventral surgical approach allowing partial ostectomy of the dens of the axis was used to facilitate reduction. Results: Recovery from surgery was uneventful and the pony remained comfortable without neurologic deficits. Both neck stiffness...
Evaluation of a minimally invasive arthrodesis technique for the carpometacarpal joint in horses.
Veterinary surgery : VS    March 11, 2011   Volume 40, Issue 4 464-472 doi: 10.1111/j.1532-950X.2011.00810.x
Panizzi L, Barber SM, Lang HM, Allen AL, Woodbury MR.To evaluate a minimally invasive technique for arthrodesis of the carpometacarpal (CMC) joint in horses. Methods: Experimental study. Methods: Healthy horses (n=6). Methods: A 5.5 mm, 3-drill tract arthrodesis technique was evaluated in 1 randomly selected CMC joint in each of 6 normal horses. Peak vertical ground reaction force (GRF) values were recorded before surgery and at 6, 8, and 12 months thereafter. Radiographic and clinical lameness scores were assigned at regular intervals until 12 months after surgery when the horses were euthanatized. Gross and histologic examinations were perfo...
Sonographic characteristics of intraabdominal abscessation and lymphadenopathy attributable to Rhodococcus equi infections in foals. Reuss SM, Chaffin MK, Schmitz DG, Norman TE.The sonographic characteristics of intraabdominal abscesses in 11 foals and intraabdominal lymphadenitis in five foals with Rhodococcus equi infections are presented. Intraabdominal abscesses were usually present in the ventral abdomen adjacent to the ventral body wall, well-marginated, and contained a mixed or complex echo pattern. Lymphadenitis appeared as singular or multiple clusters of lymph nodes of mixed echogenicity adjacent to any portion of the gastrointestinal tract or body wall. Sonographic findings were supported by necropsy examinations, but sonographic measurements consistently ...
Comparison of ileal and rectal biopsies in the diagnosis of equine grass sickness.
The Veterinary record    March 4, 2011   Volume 168, Issue 10 266 doi: 10.1136/vr.c6349
Mair TS, Kelley AM, Pearson GR.No abstract available
Retrospective study of scintigraphic and radiological findings in 21 cases of enostosis-like lesions in horses.
The Veterinary record    March 4, 2011   Volume 168, Issue 12 326 doi: 10.1136/vr.c6168
O'Neill HD, Bladon BM.Records of horses admitted to a veterinary surgery in the UK for lameness investigation during 2000 to 2008 were reviewed. Twenty-one horses were identified with both scintigraphic and radiological evidence of enostosis-like lesions (ELLs), in which 68 individual foci of increased radiopharmaceutical uptake were confirmed in 57 long bones. The presenting lameness was attributed to ELLs in 15 of 21 (71 per cent) horses; the remainder were thought to be incidental findings. Five horses were subjected to a repeat examination, four of which showed the occurrence of new lesions in the same or diffe...
Ocular anomalies in a herd of Exmoor ponies in Canada.
Veterinary ophthalmology    March 4, 2011   Volume 14, Issue 2 100-108 doi: 10.1111/j.1463-5224.2010.00847.x
Pinard CL, Basrur PK.To characterize the ocular anomalies, determine their recurrence in families and assess the mode of inheritance of the most prevalent anomalies through pedigree analysis in a herd of Exmoor ponies. Methods: Thirty Exmoor ponies residing in south-western Ontario, Canada. Methods: Ophthalmic examination was performed using direct ophthalmoscopy, slit-lamp biomicroscopy and indirect ophthalmoscopy, pre- and post-pupillary dilation. Following compilation of ocular findings, pedigree analysis was conducted to assess the recurrence pattern of specific anomalies in families and the data were tested f...
Penetrating metallic foreign bodies as a cause of peritonitis in 3 horses.
The Canadian veterinary journal = La revue veterinaire canadienne    March 2, 2011   Volume 51, Issue 12 1400-1404 
Lohmann KL, Lewis SR, Wobeser B, Allen AL.Three cases of penetrating metallic foreign bodies causing peritonitis in horses are reported. These cases were presented with varying clinical complaints and duration of clinical signs. Entry of foreign bodies into the abdominal cavity through the skin and body wall is reported for the first time. Corps étrangers métalliques pénétrants comme cause de péritonite chez 3 chevaux. Trois cas de corps étrangers métalliques pénétrants ayant causé une péritonite chez des chevaux sont signalés. Ces cas ont été présentés avec des plaintes cliniques différentes et une durée variable de...
Rattlesnake envenomation in horses: 58 cases (1992-2009).
Journal of the American Veterinary Medical Association    March 2, 2011   Volume 238, Issue 5 631-635 doi: 10.2460/javma.238.5.631
Fielding CL, Pusterla N, Magdesian KG, Higgins JC, Meier CA.To characterize signalment, clinical and laboratory findings, treatment, and outcome in horses with rattlesnake envenomation in northern California. Methods: Retrospective case series. Methods: 58 client-owned horses evaluated for rattlesnake envenomation at 2 referral hospitals from 1992 to 2009. Methods: Records of horses with rattlesnake envenomation were reviewed, and data concerning signalment, clinical and laboratory findings, treatment, and outcome were collected. In addition, a rattlesnake-bite severity score (RBSS) was assigned to each horse. Variables were compared between horses tha...
Desmotomy of the accessory ligament of the deep digital flexor tendon in the forelimb of 24 horses 2 years and older.
Veterinary surgery : VS    March 1, 2011   Volume 40, Issue 3 272-276 doi: 10.1111/j.1532-950X.2011.00815.x
Yiannikouris S, Schneider RK, Sampson SN, Roberts G.To report outcome after desmotomy of the accessory ligament of the deep digital flexor tendon (ALDDFT) in adult horses (≥2 years) for treatment of desmitis of the ALDDFT or flexural deformity of the distal interphalangeal joint (FDDIJ). Methods: Case series. Methods: Horses with desmitis of the ALDDFT (n=9) and FDDIJ (n=15). Methods: Records (April 1996-July 2008) of 24 adult horses (mean age, 6.7 years) that had ALDDFT desmotomy were reviewed. Follow-up data was obtained 12-120 months after desmotomy. Results: Outcome was available for 22 horses; 18 (82%; 6 of 8 horses with desmitis of the ...
Evaluation of a tenoscopic approach for desmotomy of the accessory ligament of the deep digital flexor tendon in horses.
Veterinary surgery : VS    March 1, 2011   Volume 40, Issue 3 266-271 doi: 10.1111/j.1532-950X.2011.00801.x
Caldwell FJ, Waguespack RW.To develop a tenoscopic approach for desmotomy of the accessory ligament of the deep digital flexor tendon (AL-DDFT) in horses. Methods: Experimental. Methods: Cadaveric forelimbs (n=10) and 4 forelimbs from 2 horses anesthetized for terminal teaching procedures, and 12 forelimbs of 6 experimental horses. Methods: Saline distention of the carpal flexor sheath facilitated insertion of an arthroscope into the distal medial aspect of the sheath between the AL-DDFT and deep digital flexor tendon (DDFT). Location of an instrument portal on the lateral aspect of the metacarpus was identified with a ...
Diagnosis of internal and external hydrocephalus in a warmblood foal using magnetic resonance imaging.
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere    February 22, 2011   Volume 39, Issue 1 41-45 
Oey L, Müller JM, von Klopmann T, Jacobsen B, Beineke A, Feige K.No abstract available
Use of BAER to identify loss of auditory function in older horses.
Australian veterinary journal    February 18, 2011   Volume 89, Issue 3 73-76 doi: 10.1111/j.1751-0813.2010.00682.x
Wilson WJ, Mills PC, Dzulkarnain AA.To use the brainstem auditory evoked response (BAER) to test the hypothesis that auditory function could be worse in older horses than in younger horses. Methods: BAER waveforms in response to click stimuli were measured in five younger horses (5-8 years) and four older horses (17-22 years). Results: Compared with the younger horses, the older horses showed significantly (P < 0.02) worse BAER thresholds and significantly (P < 0.02) worse BAER wave V amplitudes to the 90 decibels above normal hearing level stimulus. These results were consistent with partial deafness in the older horse gr...
Ultrasonographic findings in horses with foot pain but without radiographically detectable osseous abnormalities. Rabba S, Bolen G, Verwilghen D, Salciccia A, Busoni V.Foot pain is an important cause of lameness in horses. When horses with foot pain have no detectable radiographic abnormalities, soft-tissue assessment remains a diagnostic challenge without magnetic resonance (MR) imaging. Ultrasonography can provide an alternative to MR imaging when that modality is not available but the extent of changes that might be seen has not been characterized. We reviewed the ultrasonographic findings in 39 horses with lameness responding positively to anesthesia of the palmar digital nerves and without radiographically detectable osseous abnormalities. Thirty of the...
An accessory bypass tract masked by the presence of atrial fibrillation in a horse.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology    February 15, 2011   Volume 13, Issue 1 79-83 doi: 10.1016/j.jvc.2010.10.002
Jesty SA, Kraus MS, Johnson AL, Gelzer AR, Bartol J.Accessory bypass tracts are rarely documented in horses. Here, we present a case of an accessory bypass tract which was initially masked by the presence of atrial fibrillation. Evidence of ventricular pre-excitation was recognized after cardioversion to normal sinus rhythm and the horse was diagnosed with Wolff-Parkinson-White Syndrome. In people, atrial fibrillation in the presence of an accessory bypass tract is considered dangerous due to the risk of sudden cardiac death. Although we did not consider this horse safe to ride, he continues to compete successfully and has not had recurrence of...
Intrathecal deep digital flexor tenectomy for treatment of septic tendonitis/tenosynovitis in four horses.
Veterinary surgery : VS    February 11, 2011   Volume 40, Issue 3 284-290 doi: 10.1111/j.1532-950X.2011.00795.x
Marsh CA, Watkins JP, Schneider RK.To describe partial removal of the intrathecal component of the deep digital flexor tendon (DDFT) in horses with chronic septic DDF tendonitis and tenosynovitis unresponsive to conventional therapy, and to report long-term outcome. Methods: Case series. Methods: Horses (n=4). Methods: Four horses with chronic septic DDF tendonitis and tenosynovitis were treated by surgical tenectomy of the intrathecal component of the DDFT, followed by stabilization in casts and subsequent corrective shoeing. All horses were previously managed unsuccessfully with combinations of conventional therapy consisting...
Repetitive stimulation of the common peroneal nerve as a diagnostic aid for botulism in foals.
Journal of veterinary internal medicine    February 11, 2011   Volume 25, Issue 2 365-372 doi: 10.1111/j.1939-1676.2011.0682.x
Aleman M, Williams DC, Jorge NE, Magdesian KG, Brosnan RJ, Feary DJ, Hilton HG, Kozikowski TA, Higgins JK, Madigan JE, Lecouteur RA.Botulism is a potentially fatal paralytic disorder for which definitive diagnosis is difficult. Objective: To determine if repetitive stimulation of the common peroneal nerve will aid in the diagnosis of botulism in foals. Methods: Four control and 3 affected foals. Methods: Validation of the test in healthy foals for its comparison in foals with suspected botulism. Controls were anesthetized and affected foals were sedated to avoid risks of anesthesia. The common peroneal nerve was chosen for its superficial location and easy access. Stimulating electrodes were placed along the common peronea...
Efficacy of a 2-dose regimen of a sustained release ceftiofur suspension in horses with Streptococcus equi subsp. zooepidemicus bronchopneumonia.
Journal of veterinary pharmacology and therapeutics    February 9, 2011   Volume 34, Issue 5 442-447 doi: 10.1111/j.1365-2885.2011.01267.x
McClure S, Sibert G, Hallberg J, Bade D.The efficacy and safety of sustained release ceftiofur administered twice, 4 days apart, for treatment of horses with naturally acquired Streptococcus equi subsp. zooepidemicus (Strep. zoo.) pneumonia was evaluated in a multicenter, placebo-controlled, double-blinded, randomized clinical trial. The study included 373 horses (278 treated and 95 placebos) with naturally acquired pneumonia. Inclusion in the statistical analyses for treatment efficacy for Strep. zoo. required recovery of ≥10(4) CFU/mL of Strep. zoo. on the primary isolation plate which resulted in 201 cases (145 treated and 56 p...
The healing effects of a topical phytogenic ointment on insect bite hypersensitivity lesions in horses.
Tijdschrift voor diergeneeskunde    February 8, 2011   Volume 136, Issue 1 20-26 
van den Boom R, Kempenaars M, van Oldruitenborgh-Oosterbaan MM.Insect bite hypersensitivity (IBH) is the most common cause of pruritus in horses and is a serious welfare issue for affected animals. In this study, the effect of a topical phytogenic ointment on the healing of cutaneous lesions was investigated in a double-blind trial involving 26 horses with I B H. The number of lesions and their total surface area were recorded on days 0, 7, and 21 in horses treated for 3 weeks with either verum or placebo ointment. After unblinding of treatment assignment, the horses that had been treated with the placebo ointment received the verum preparation for an add...
Vulnerability of an equine pericardial roll graft to Gram-positive cocci after graft replacement for a ruptured infected abdominal aorta.
Interactive cardiovascular and thoracic surgery    February 8, 2011   Volume 12, Issue 5 866-868 doi: 10.1510/icvts.2010.262667
Yamamoto H, Yamamoto F, Tanaka F, Nishikawa Y.We describe the influence of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia on histopathological alteration of a glutaraldehyde-fixed equine pericardial roll (EPR) graft in a 77-year-old male who underwent in-situ EPR replacement of a ruptured infected abdominal aorta with concomitant repair of the perforated duodenum. The patient died of circulatory failure after septic shock due to MRSA infection and gastrointestinal bleeding on postoperative day (POD) 23. The autopsy revealed no perforation of the EPR graft or anastomotic disruption between the native abdominal aorta and EPR ...
Transient localized sweating in a horse after administration of procaine penicillin.
Compendium (Yardley, PA)    February 1, 2011   Volume 33, Issue 2 E3 
Moorman V, Stewart AJ, Purohit RC.No abstract available
Serum free cortisol fraction in healthy and septic neonatal foals.
Journal of veterinary internal medicine    January 31, 2011   Volume 25, Issue 2 345-355 doi: 10.1111/j.1939-1676.2010.0667.x
Hart KA, Barton MH, Ferguson DC, Berghaus R, Slovis NM, Heusner GL, Hurley DJ.Relative cortisol insufficiency occurs in septic foals and impacts survival. Serum free (biologically available) cortisol concentration might be a better indicator of physiologic cortisol status than serum total cortisol concentration in foals. Objective: In septic foals, (1) low free cortisol concentration correlates with disease severity and survival and (2) predicts disease severity and outcome better than total cortisol concentration. Methods: Fifty-one septic foals; 11 healthy foals; 6 healthy horses. Methods: In this prospective clinical study, foals meeting criteria for sepsis at admiss...
Magnetic resonance anatomy of the carpus of the horse described from images acquired from low-field and high-field magnets. Nagy A, Dyson S.Cadaver carpi of 30 mature horses with no history of carpal or proximal metacarpal pain were examined using low-field (0.27 T) and high-field (1.5 T) magnetic resonance imaging (MRI). Normal MRI anatomy in transverse, sagittal, and dorsal plane images was determined by comparison with anatomical specimens and standard texts. Subchondral bone and cortical bone thickness measurements were obtained from standardised sites. There was variable subchondral bone thickness in the radius and carpal bones; subchondral bone thickness was consistently larger at dorsal compared with palmar sites in the...
Comparison of water manometry to 2 commercial electronic pressure monitors for central venous pressure measurement in horses.
Journal of veterinary internal medicine    January 31, 2011   Volume 25, Issue 2 303-306 doi: 10.1111/j.1939-1676.2010.0670.x
Norton JL, Nolen-Walston RD, Underwood C, Slack J, Boston R, Dallap BL.Central venous pressure (CVP) customarily has been measured in veterinary patients with water manometry. However, many institutions are now using stallside electronic monitors in both anesthesia and intensive care units for many aspects of patient monitoring. Objective: Electronic stall side monitoring devices will agree with water manometry for measurement of CVP in horses. Methods: Ten healthy adult horses from the university research herd. Methods: Central venous catheters were placed routinely, and measurements were obtained in triplicate with each of the 3 methods every 12 hours for 3 day...
Haemoperitoneum in horses: a retrospective review of 54 cases.
The Veterinary record    January 25, 2011   Volume 167, Issue 14 514-518 doi: 10.1136/vr.c4569
Conwell RC, Hillyer MH, Mair TS, Pirie RS, Clegg PD.This retrospective study was conducted in the UK and identifies the most frequent causes, diagnoses, treatment and prognoses for short- and long-term survival in 54 cases of horses with haemoperitoneum. Clinical signs of haemorrhagic shock and colic were common, and abdominal ultrasound was very useful for the identification of haemoperitoneum. Causes of haemoperitoneum included uterine injury (22 per cent), involvement of specific blood vessels (20 per cent), splenic injury (19 per cent), neoplasia (13 per cent) and other (4 per cent). No source was identified in 22 per cent of cases. Fifty-s...
Clinical assessment and outcome of a single-layer technique for anastomosis of the small intestine in horses.
The Veterinary record    January 25, 2011   Volume 167, Issue 17 652-655 doi: 10.1136/vr.c5251
Mendez-Angulo JL, Ernst NS, Mudge MC.In order to assess postoperative outcome in horses undergoing end-to-end anastomosis of the small intestine, performed using a one-layer technique, 15 horses that underwent exploratory coeliotomy, resection of the small intestine and end-to-end anastomosis using a continuous Lembert pattern were studied. Information on the age, breed, sex, diagnosis, treatment, complications and outcome of each case were obtained from medical records. Follow-up information was obtained via telephone conversations with clients and trainers. Five of the horses had short-term postoperative complications: one had ...
Rhabdomyosarcoma in 8 horses.
Veterinary pathology    January 24, 2011   Volume 48, Issue 6 1144-1150 doi: 10.1177/0300985810395785
Castleman WL, Toplon DE, Clark CK, Heskett TW, Farina LL, Lynch TM, Bryant UK, Del Piero F, Murphy B, Edwards JF.This multi-institutional report describes 8 cases of rhabdomyosarcoma in horses. Four neoplasms were in the tongue and other areas of the mouth or head, 2 were in the abdominal wall, and 1 each was in right shoulder muscles and heart. Four rhabdomyosarcomas that were less than 10 cm in diameter were treated by surgical excision or radiation with no recurrence. Two neoplasms greater than 10 cm in diameter in the abdominal wall and the right shoulder were considered inoperable and led to decisions to euthanize the horses. Two neoplasms were incidental findings at necropsy. All the neoplasms were...
Thoracic emphysematous lymphadenitis in a foal.
Journal of comparative pathology    January 19, 2011   Volume 145, Issue 1 77-79 doi: 10.1016/j.jcpa.2010.11.010
Mendoza FJ, Perez-Ecija RA, Estepa JC.Emphysema of lymph nodes is a rare finding that has been described in different anatomical locations and related to specific diseases in different animal species. Herein is described a foal with Rhodococcus equi infection that presented with emphysema and granulomatous inflammation of the bronchial and mediastinal lymph nodes. This is the first report of emphysematous lymphadenitis in a horse.
Preliminary safety and biological efficacy studies of ethyl pyruvate in normal mature horses.
Equine veterinary journal    January 19, 2011   Volume 43, Issue 3 341-347 doi: 10.1111/j.2042-3306.2010.00214.x
Schroeder EL, Holcombe SJ, Cook VL, James MD, Gandy JC, Hauptman JG, Sordillo LM.Endotoxaemia causes substantial morbidity and mortality in horses with colic and sepsis. Ethyl pyruvate is a novel anti-inflammatory medication that improved survival in preclinical models of severe sepsis endotoxaemia and intestinal ischaemia and reperfusion in rodents, swine, sheep and dogs and may be a useful medication in horses. Objective: Ethyl pyruvate has no adverse effects in normal horses and is biologically active based on suppression of proinflammatory gene expression in endotoxin stimulated whole blood, in vitro. Methods: Physical and neurological examinations, behaviour scores, e...
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