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Topic:Clinical Findings

Clinical findings in horses encompass a range of observable signs and symptoms identified during veterinary examinations that contribute to diagnosing and managing equine health conditions. These findings can include physical observations, such as changes in behavior, posture, or gait, as well as physiological measurements like heart rate, respiratory rate, and temperature. Diagnostics may also involve laboratory tests, imaging, and other diagnostic procedures to assess organ function and detect abnormalities. Recognizing and interpreting clinical findings are essential components of veterinary practice, aiding in the identification of diseases, monitoring treatment progress, and guiding therapeutic interventions. This page brings together peer-reviewed research studies and scholarly articles that explore the methodologies, interpretations, and implications of clinical findings in the context of equine health care.
Caudal compression of the infraorbital nerve: a novel surgical technique for treatment of idiopathic headshaking and assessment of its efficacy in 24 horses.
Equine veterinary journal    May 8, 2009   Volume 41, Issue 2 165-170 doi: 10.2746/042516408x342966
Roberts VL, McKane SA, Williams A, Knottenbelt DC.REASONS FOR DESIGNING AND REPORTING TECHNIQUE: Idiopathic headshaking has remarkable similarities to human neuropathic facial pain syndromes associated with post herpetic and trigeminal neuralgia. These derive from abnormal sensory function within the peripheral or central pathways of the trigeminal nerve (TgN). Limiting input from the TgN can be helpful in controlling the perception of pain. Rhizotomy of the infraorbital branch of the TgN as it emerges from the infraorbital canal has been reported but has a poor efficacy. A novel technique involves compression of the nerve at a more caudal lo...
Is there a relationship between clinical presentation, diagnostic and radiographic findings and outcome in horses with osteoarthritis of the small tarsal joints?
Equine veterinary journal    May 8, 2009   Volume 41, Issue 2 118-123 doi: 10.2746/042516408x345107
Byam-Cook KL, Singer ER.Despite the possibility that sound horses may have radiographic signs consistent with osteoarthritis of the small tarsal joints (OA-STJ), a diagnosis of 'bone spavin' as a cause of lameness is often made based only on radiographic examination. Objective: To determine whether severity of radiographic change and response to treatment are correlated with the duration and degree of lameness and the response to intraarticular anaesthesia in horses with OA-STJ. Methods: A retrospective study of all horses that showed a positive response to intra-articular anaesthesia of the STJ was performed. Detail...
Clinical findings and serum cardiac troponin I concentrations in horses after intragastric administration of sodium monensin. Divers TJ, Kraus MS, Jesty SA, Miller AD, Mohammed HO, Gelzer AR, Mitchell LM, Soderholm LV, Ducharme NG.Six adult horses were administered sodium monensin, 1.0-1.5 mg/kg, via gastric gavage. Anorexia and/or diarrhea occurred within 24 hr after monensin administration in all 6 horses. Cardiac disease and dysfunction were evaluated by both elevations in heart rate, echocardiography, and an increase in serum concentrations of cardiac troponin I (cTnI), occurred in 4 horses. The development and severity of cardiac disease was likely affected by the monensin dose, vehicle (water or corn oil) mixed with monensin, and/or whether the monensin was administered to fed or fasted horses. Initial increases i...
Effects of extracorporeal shock wave therapy on wounds of the distal portion of the limbs in horses.
Journal of the American Veterinary Medical Association    May 2, 2009   Volume 234, Issue 9 1154-1161 doi: 10.2460/javma.234.9.1154
Morgan DD, McClure S, Yaeger MJ, Schumacher J, Evans RB.To evaluate the effects of focused, extracorporeal shock wave therapy (ESWT) on the healing of wounds of the distal portion of the limbs in horses. Methods: Randomized controlled trial. Methods: 6 healthy adult horses. Methods: In each horse, a 4-cm-diameter full-thickness wound that included underlying periosteum was created on the dorsomedial aspect of each metacarpus and two 3-cm-diameter full-thickness wounds that included underlying periosteum were created on the dorsomedial aspect of each metatarsus. One randomly selected metacarpal wound and a randomly selected pair of metatarsal wounds...
Correlation of the Havemeyer endoscopic laryngeal grading system with histopathological changes in equine Cricoarytenoideus dorsalis muscles.
Irish veterinary journal    May 1, 2009   Volume 62, Issue 5 334-338 doi: 10.1186/2046-0481-62-5-334
Collins N, Milne E, Hahn C, Dixon P.The establishment of a single validated endoscopic laryngeal grading system for assessing recurrent laryngeal neuropathy (RLN) is desirable to facilitate direct comparisons between the findings of different clinical and research groups worldwide. The objective of this study was to assess the relationship between the Havemeyer endoscopic laryngeal grading system and histopathological changes consistent with RLN in the left cricoarytenoideus dorsalis (CAD) muscle of horses of different breeds with a full range of clinical severities of RLN, i.e., from normal endoscopic laryngeal function to comp...
The computed tomographic appearance of equine temporohyoid osteoarthropathy. Hilton H, Puchalski SM, Aleman M.Equine temporohyoid osteoarthropathy is characterized by progressive osseous proliferation of the temporohyoid articulation and surrounding structures. The diagnosis has generally been made using radiography and endoscopy of the guttural pouch. Recently, computed tomography (CT) has been used in the diagnosis of temporohyoid osteoarthropathy. This study was performed to determine the CT imaging characteristics of temporohyoid osteoarthropathy and to compare these to radiographic and endoscopic findings. CT scans from 16 horses with a final diagnosis of temporohyoid osteoarthropathy were review...
Immunohistochemical analysis of laryngeal muscles in normal horses and horses with subclinical recurrent laryngeal neuropathy.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society    April 27, 2009   Volume 57, Issue 8 787-800 doi: 10.1369/jhc.2009.953844
Rhee HS, Steel CM, Derksen FJ, Robinson NE, Hoh JF.We used immunohistochemistry to examine myosin heavy-chain (MyHC)-based fiber-type profiles of the right and left cricoarytenoideus dorsalis (CAD) and arytenoideus transversus (TrA) muscles of six horses without laryngoscopic evidence of recurrent laryngeal neuropathy (RLN). Results showed that CAD and TrA muscles have the same slow, 2a, and 2x fibers as equine limb muscles, but not the faster contracting fibers expressing extraocular and 2B MyHCs found in laryngeal muscles of small mammals. Muscles from three horses showed fiber-type grouping bilaterally in the TrA muscles, but only in the le...
Double-outlet right ventricle in a 10-month-old Friesian filly.
Australian veterinary journal    April 23, 2009   Volume 87, Issue 5 204-209 doi: 10.1111/j.1751-0813.2009.00424.x
Fennell L, Church S, Tyrell D, Forbes G, Charles J, McCowan C, Savage C.A 10-month-old Friesian filly had a presentation that was consistent with chronic left- and right-sided congestive heart failure. Clinical pathology findings included abnormal haematological and biochemical variables, abnormal blood gas values and increased serum concentration of cardiac troponin I. Echocardiography revealed cardiac chamber dilation and dextropositioning of the aorta. Radiography revealed a generally enlarged heart and pulmonary interstitial infiltration. These findings were supported at necropsy and the diagnosis of double-outlet right ventricle was confirmed. The pathologica...
Pressure on the horse’s withers with three styles of blanket.
Veterinary journal (London, England : 1997)    April 23, 2009   Volume 184, Issue 1 52-55 doi: 10.1016/j.tvjl.2009.03.024
Clayton HM, Kaiser LJ, Nauwelaerts S.The objective of this study was to compare total force and localised pressure on horses' withers with three blanket styles (straight cut, V-shaped insert, cutback withers). Three pressure recordings, each of 5s duration, were taken in order to determine blanket pressure on the withers during standing and walking in 12 horses. Means+/-SD were calculated for the following variables and compared across blankets: total force, mean pressure, maximal pressure, and area with pressure >4 kPa. For standing trials, the blanket with the V-shaped insert had the lowest total force and smallest area with...
Polymorphisms in SPINK5 do not associate with insect bite hypersensitivity in Icelandic horses born in Sweden.
Animal genetics    April 20, 2009   Volume 40, Issue 5 790-791 doi: 10.1111/j.1365-2052.2009.01890.x
Andersson LS, Högström C, Mikko S, Eriksson S, Grandinson K, Broström H, Frey R, Sundquist M, Lindgren G.No abstract available
Transparent equine collagen biomatrix as dural repair. A prospective clinical study.
Acta neurochirurgica    April 1, 2009   Volume 151, Issue 5 537-543 doi: 10.1007/s00701-009-0290-9
Gazzeri R, Neroni M, Alfieri A, Galarza M, Faiola A, Esposito S, Giordano M.Numerous materials have been used to replace defects in the dura mater as result of neurosurgical and spinal procedures. Tissudura is a biomatrix made of cross-linked equine collagen fibrils, mainly of the interstitial type I. The specially engineered dura-like layered structure provides a non porous primary water tight structure, is transparent and allows verification of the efficacy of cerebral hemostasis. Methods: A consecutive series of patients between 18 years and 75 years of age were prospectively enrolled from three separate European institutions between May 2007 and February 2008. All...
Abstracts of the 3rd Congress of the European College of Equine Internal Medicine. January 28-30, 2009. Barcelona, Spain.
Journal of veterinary internal medicine    March 27, 2009   Volume 23, Issue 2 420-439 doi: 10.1111/j.1939-1676.2008.00284.x
No abstract available
Racing performance after combined prosthetic laryngoplasty and ipsilateral ventriculocordectomy or partial arytenoidectomy: 135 Thoroughbred racehorses competing at less than 2400 m (1997-2007).
Equine veterinary journal    March 24, 2009   Volume 41, Issue 1 70-75 doi: 10.2746/042516408x343163
Witte TH, Mohammed HO, Radcliffe CH, Hackett RP, Ducharme NG.The success of combined prosthetic laryngoplasty with ipsilateral ventriculocordectomy (LPVC) has not been compared to that of partial arytenoidectomy (PA) in a clinical population. Objective: In Thoroughbred (TB) racehorses: (1) earnings after LPVC are unaffected by the severity of recurrent laryngeal neuropathy (RLN) (laryngeal grade III vs. grade IV); (2) LPVC and PA yield similar results in the treatment of grade III RLN; (3) performance outcome following PA is independent of diagnosis (RLN vs. unilateral arytenoid chondritis [UAC]); and (4) neither LPVC nor PA returns horses to the level ...
Lesions of the deep digital flexor tendon in the digit: a correlative MRI and post mortem study in control and lame horses.
Equine veterinary journal    March 24, 2009   Volume 41, Issue 1 25-33 doi: 10.2746/042516408x343028
Blunden A, Murray R, Dyson S.Lameness associated with lesions of the deep digital flexor tendon (DDFT) in the digit is now recognised as an important cause of lameness, but there is currently limited information about the pathological nature of the lesions. Objective: To compare: signal intensity changes on magnetic resonance images with histopathology; and histopathological changes in the DDFT from horses with no history of foot-related lameness (Group C) and horses with lesions of the DDFT confirmed using magnetic resonance imaging (MRI) (Group D). Methods: Transverse sections of the DDFT were harvested from 3 sites in ...
Association of blood lactate concentration and outcome in foals.
Journal of veterinary internal medicine    March 20, 2009   Volume 23, Issue 3 598-605 doi: 10.1111/j.1939-1676.2009.0277.x
Wotman K, Wilkins PA, Palmer JE, Boston RC.Lactate concentration in blood or plasma ([LAC]) and change in [LAC] are associated with survival in sick foals. Objective: [LAC] and change in [LAC] over time are associated with survival at 96 hours and discharge in neonatal foals. Furthermore [LAC] and change in [LAC] over time correlate with blood culture results and blood pressure at admission. Methods: Two hundred and twenty-five foals consecutively admitted to a Neonatal Intensive Care Unit. Methods: Retrospective case review. Foals <or=30 days of age with [LAC] from arterial (190) or umbilical (35) blood gas analysis ([LAC](BG)) at ...
Doppler-derived evidence of severe pulmonary arterial hypertension in a pony with recurrent airway obstruction.
The Veterinary record    March 17, 2009   Volume 164, Issue 11 340-341 doi: 10.1136/vr.164.11.340
Lightowler C, Guglielmini C, Pidal G, Chiaramonte P.No abstract available
Comparison of clinical, microbiologic, and clinicopathologic findings in horses positive and negative for Clostridium difficile infection.
Journal of the American Veterinary Medical Association    March 17, 2009   Volume 234, Issue 6 777-784 doi: 10.2460/javma.234.6.777
Ruby R, Magdesian KG, Kass PH.To compare clinical, microbiologic, and clinicopathologic findings among horses infected with Clostridium difficile that had toxin A in their feces, horses with evidence of C difficile infection that were negative for toxin A in their feces, and horses with diarrhea that were negative for C difficile infection. Methods: Cross-sectional study. Methods: 292 horses and foals with diarrhea. Methods: Feces were submitted for microbial culture and tested for the C difficile antigen glutamate dehydrogenase and for toxin A with a commercial ELISA. Results: Horses with toxin A in their feces had higher...
Clinical and echocardiographic features of mild mitral valve regurgitation in 108 horses.
Veterinary journal (London, England : 1997)    March 9, 2009   Volume 183, Issue 2 166-171 doi: 10.1016/j.tvjl.2009.01.020
Imhasly A, Tschudi PR, Lombard CW, Gerber V.The clinical and echocardiographic characteristics of 108 horses with echocardiographically confirmed mild mitral valve regurgitation (MR) were investigated along with its clinical progression. Follow-up consisted of a re-examination of 28 horses and questionnaires were used to obtain information on a further 43 cases. Thirty-seven horses with mild MR were lost to follow-up. Horses with mild MR were re-examined between 2 and 9 years (3.8+/-1.8 years) following first presentation, with mild MR still present and a small, but statistically significant (P=0.049) increase of left ventricular diamet...
Neuropathology of naturally occurring Trypanosoma evansi infection of horses.
Veterinary pathology    March 6, 2009   Volume 46, Issue 2 251-258 doi: 10.1354/vp.46-2-251
Rodrigues A, Fighera RA, Souza TM, Schild AL, Barros CS.The clinical signs and pathology of the central nervous system in 9 horses with naturally occurring neurologic disease due to Trypanosoma evansi are described. The clinical course was 2 to 20 days; clinical signs included marked ataxia, blindness, head tilt and circling, hyperexcitability, obtundity, proprioceptive deficits, head pressing, and paddling movements. Grossly, asymmetric leukoencephalomalacia with yellowish discoloration of white matter and flattening of the gyri were observed in the brain of 7 of 9 horses. Histologically, all 9 horses had necrotizing encephalitis that was most sev...
Use of kinetic gait analysis for detection, quantification, and differentiation of hind limb lameness and spinal ataxia in horses.
Journal of the American Veterinary Medical Association    March 3, 2009   Volume 234, Issue 5 644-651 doi: 10.2460/javma.234.5.644
Ishihara A, Reed SM, Rajala-Schultz PJ, Robertson JT, Bertone AL.To evaluate use of kinetic gait analysis for detection, quantification, and differentiation of hind limb lameness and spinal ataxia in horses. Methods: Prospective clinical study. Methods: 36 horses. Procedures-Kinetic gait analysis with a force plate was performed for 12 clinically normal horses, 12 horses with hind limb lameness, and 12 horses with spinal ataxia. Kinetic variables were compared among groups, correlated to subjective grading, and used to build predictive models to assess the accuracy of discrimination. Results: Subsets of kinetic variables were characteristically altered in a...
Surgical resection of a dysgerminoma in a mare.
Australian veterinary journal    February 28, 2009   Volume 87, Issue 3 110-112 doi: 10.1111/j.1751-0813.2009.00392.x
Harland S, Smith C, Mogg T, Horadagoda N, Dart A.A mare was referred for further evaluation of a mass found in the left caudal abdomen during a routine postpartum reproductive palpation. The mare was clinically normal with no history of health problems. Ultrasonographic examination of the mass confirmed its presence, but the origin of the mass could not be accurately determined. Routine haematology and serum biochemistry results were within normal limits. The mare was initially treated conservatively with antibiotics, but the mass continued to increase in size, so it was surgically excised. The mass involved the left ovary. The mare showed t...
Characterization of the magic angle effect in the equine deep digital flexor tendon using a low-field magnetic resonance system. Spriet M, McKnight A.Three isolated equine limbs were imaged with a low-field magnetic resonance system with a vertical magnetic field. Each limb was scanned in multiple positions with mild variation of the angle between the magnetic field and the long axis of the limb. When the long axis of the limb was not perpendicular to the magnetic field, a linear hyperintense signal was present at the palmar aspect of one of the deep digital flexor tendon lobes, at the level of the navicular bone and collateral sesamoidean ligaments, in proton density and T1-weighted pulse sequences. With increased angulation of the limb, t...
Magnetic resonance imaging findings of desmopathy of the collateral ligaments of the equine distal interphalangeal joint. Gutierrez-Nibeyro SD, White NA, Werpy NM, Tyrrell L, Allen KA, Sullins KE, Mitchell RD.We report the use of a low-field magnetic resonance (MR) imaging system for the detection of desmopathy of the collateral ligament of the distal interphalangeal joint and the long-term outcome. Twenty horses were studied and their medical records and MR images were reviewed retrospectively. Long-term follow-up information was obtained by telephonic questionnaires of owners, trainers, or referring veterinarians. Desmopathy of the medial collateral ligament (80%) and enthesopathy of the affected collateral ligament (80%) were common MR imaging features. Treatment consisted of stall rest followed...
Castration of horses under total intravenous anaesthesia: analgesic effects of lidocaine.
Veterinary anaesthesia and analgesia    February 26, 2009   Volume 36, Issue 2 173-179 doi: 10.1111/j.1467-2995.2008.00445.x
Portier KG, Jaillardon L, Leece EA, Walsh CM.To evaluate the effects of local anaesthesia with lidocaine for castration of horses under intravenous anaesthesia. Methods: Prospective, randomized, blinded clinical trial. Methods: Fifteen equidae, scheduled to undergo castration under total intravenous anaesthesia, were randomly distributed in two groups. One group received lidocaine injections (group L: two ponies, four horses, two donkeys) and the other received saline (group S: two ponies, three horses, two donkeys). Methods: Behaviour, heart rate (HR) and respiratory rate (f(R)) were evaluated prior to anaesthesia. Body mass was measure...
Evaluation of polysulfated glycosaminoglycan or sodium hyaluronan administered intra-articularly for treatment of horses with experimentally induced osteoarthritis.
American journal of veterinary research    February 24, 2009   Volume 70, Issue 2 203-209 doi: 10.2460/ajvr.70.2.203
Frisbie DD, Kawcak CE, McIlwraith CW, Werpy NM.To assess clinical, biochemical, and histologic effects of polysulfated glycosaminoglycan (PSGAG) or sodium hyaluronan administered intra-articularly in treatment of horses with experimentally induced osteoarthritis. Methods: 24 horses. Methods: Osteoarthritis was induced arthroscopically in 1 middle carpal joint of all horses. Eight horses received hyaluronan (20 mg) and amikacin (125 mg) intra-articularly on study days 14, 21, and 28. Eight horses received PSGAG (250 mg) and amikacin (125 mg) intra-articularly on study days 14, 21, and 28. Eight control horses received 2 mL of saline (0.9% N...
Circadian intraocular pressure rhythms in athletic horses under different lighting regime.
Chronobiology international    February 13, 2009   Volume 26, Issue 2 348-358 doi: 10.1080/07420520902751035
Bertolucci C, Giudice E, Fazio F, Piccione G.The present study was undertaken to investigate the existence of intraocular pressure (IOP) rhythms in athletic thoroughbred horses maintained under a 24 h cycle of light and darkness (LD) or under constant light (LL) or constant dark (DD) conditions. We identified an IOP circadian rhythm that is entrained to the 24 h LD cycle. IOP was low during the dark phase and high during the light phase, with a peak at the end of the light phase (ZT10). The circadian rhythm of IOP persisted in DD (with a peak at CT9.5), demonstrating an endogenous component in IOP rhythm. As previously shown in other mam...
Selected urogenital surgery concerns and complications.
The Veterinary clinics of North America. Equine practice    February 11, 2009   Volume 24, Issue 3 643-ix doi: 10.1016/j.cveq.2008.10.007
Embertson RM.This article discusses selected urogenital surgeries. The discussion focuses on perioperative concerns and complications. The ideal approach to addressing complications resulting from disease processes or surgery is to avoid them. This approach requires knowledge of what can go wrong, gained by personal experience and that shared by others. The better one is able to anticipate potential complications, the more likely complications can be avoided.
Preface. Surgical complications and management strategies.
The Veterinary clinics of North America. Equine practice    February 11, 2009   Volume 24, Issue 3 xiii-xv doi: 10.1016/j.cveq.2008.11.002
Goodrich LR.No abstract available
Complications of unilateral weight bearing.
The Veterinary clinics of North America. Equine practice    February 11, 2009   Volume 24, Issue 3 621-ix doi: 10.1016/j.cveq.2008.10.006
Baxter GM, Morrison S.The most common and significant complication of excessive unilateral weight bearing in adult horses is support limb laminitis. Young horses with unilateral lameness problems develop support limb laminitis infrequently compared with adult horses.
Complications of orthopaedic surgery in horses.
The Veterinary clinics of North America. Equine practice    February 11, 2009   Volume 24, Issue 3 591-viii doi: 10.1016/j.cveq.2008.11.001
Richardson DW.Complications are a price all surgeons eventually pay. Experience and increasing skill will decrease many of them but certainly not all. The most important thing is for the surgeon to react correctly to a complication. Acknowledge the mistake (or bad luck) quickly and take whatever steps you can to correct the problem. Because so many equine orthopaedic cases have the potential for complications, recognizing and responding properly to these complications are imperative for successful outcomes. Discussion of the most common complications, their prevention and corrections, is presented.
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