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Topic:Clinical Findings

Clinical findings in horses encompass a range of observable signs and symptoms identified during veterinary examinations that contribute to diagnosing and managing equine health conditions. These findings can include physical observations, such as changes in behavior, posture, or gait, as well as physiological measurements like heart rate, respiratory rate, and temperature. Diagnostics may also involve laboratory tests, imaging, and other diagnostic procedures to assess organ function and detect abnormalities. Recognizing and interpreting clinical findings are essential components of veterinary practice, aiding in the identification of diseases, monitoring treatment progress, and guiding therapeutic interventions. This page brings together peer-reviewed research studies and scholarly articles that explore the methodologies, interpretations, and implications of clinical findings in the context of equine health care.
Building on the achievements of clinical research.
Equine veterinary journal    August 2, 2008   Volume 40, Issue 4 299-300 doi: 10.2746/042516408X302519
Pinchbeck GL, Proudman CJ.No abstract available
Post operative ileus: to be or not to be?
Equine veterinary journal    August 2, 2008   Volume 40, Issue 4 295-296 doi: 10.2746/042516408X302537
Merritt AM, Blikslager AT.No abstract available
Complications and survival associated with surgical compared with medical management of horses with duodenitis-proximal jejunitis.
Equine veterinary journal    August 2, 2008   Volume 40, Issue 4 373-378 doi: 10.2746/042516408X302492
Underwood C, Southwood LL, McKeown LP, Knight D.Based on clinical observation, it is hypothesised that horses with duodenitis-proximal jejunitis (DPJ) that are treated surgically have a shorter duration, smaller volume, and slower rate of nasogastric reflux (NGR) compared to horses treated medically, are more likely to develop diarrhoea than medically managed cases, and have a higher incisional infection rate than a sample population of horses undergoing abdominal exploration for gastrointestinal disease other than DPJ. Objective: To compare: 1) duration, volume and rate of NGR and the percentage of horses with diarrhoea between medically a...
Peripheral blood leukocytes.
The Veterinary clinics of North America. Equine practice    July 26, 2008   Volume 24, Issue 2 239-v doi: 10.1016/j.cveq.2008.05.003
Carrick JB, Begg AP.Assessment of peripheral blood leukocytes is the most common clinical pathology test in equine practice. It is always a part of complete body function assessment and frequently is used alone, or in conjunction with, fibrinogen to monitor response to treatment.
Veterinary Clinics of North America: Equine Practice. Preface.
The Veterinary clinics of North America. Equine practice    July 26, 2008   Volume 24, Issue 2 xi-xii doi: 10.1016/j.cveq.2008.06.001
Parry BW.No abstract available
Equine synovial fluid analysis.
The Veterinary clinics of North America. Equine practice    July 26, 2008   Volume 24, Issue 2 437-viii doi: 10.1016/j.cveq.2008.05.004
Steel CM.The most important application for synovial fluid (SF) analysis in the horse is in the diagnosis of synovial sepsis. Misdiagnosis of synovial sepsis is costly, and SF analysis makes correct diagnosis more likely, although far from certain. The precision of diagnosis may be increased with polymerase chain reaction analysis for detection of bacterial DNA in SF and with assays for various enzymes and cytokines. These tests are currently not widely available, however, and routine SF analysis remains of prime importance in diagnosis.
Clinical pathology of the foal.
The Veterinary clinics of North America. Equine practice    July 26, 2008   Volume 24, Issue 2 357-vii doi: 10.1016/j.cveq.2008.03.005
Axon JE, Palmer JE.The neonatal foal is in a period of transition between fetal and extrauterine life. The clinicopathologic findings in this period often reflect the in utero environment; thus, results need to be interpreted with the knowledge of changes that intrauterine life may produce. These changes can also assist the veterinarian in identifying a foal at high risk for developing clinical problems. The veterinarian should also be aware of the normal variations in clinicopathologic findings that occur as the foal matures. As with results from all diagnostic testing, the clinicopathologic results need to be ...
Urinary clinical pathologic findings and glomerular filtration rate in the horse.
The Veterinary clinics of North America. Equine practice    July 26, 2008   Volume 24, Issue 2 387-vii doi: 10.1016/j.cveq.2008.05.002
Savage CJ.Urinary specific gravity (USG) measurements are underused by equine ambulatory veterinarians. Urinary dipstick and USG findings can assist in the diagnosis and prognosis of many disease processes in the horse. Simple methods for measurement of the glomerular filtration rate and urinary biochemical markers can improve equine urinary diagnostic abilities in critical care patients. Fractional excretion of electrolytes and minerals assists in fluid care and in management of nutrition of horses.
Erythrocytes.
The Veterinary clinics of North America. Equine practice    July 26, 2008   Volume 24, Issue 2 225-v doi: 10.1016/j.cveq.2008.04.002
Lording PM.In this article, the normal kinetics, morphology and other unique characteristics of equine erythrocytes are reviewed, the influence of the spleen on erythrocyte values is discussed, and selected normal reference intervals are presented. In addition, the classification and causes of anemia and polycythemia are reviewed and the appropriate laboratory tests for accurate diagnosis are presented.
Exophthalmus secondary to a sinonasal cyst in a horse.
Journal of the American Veterinary Medical Association    July 17, 2008   Volume 233, Issue 2 285-288 doi: 10.2460/javma.233.2.285
Annear MJ, Gemensky-Metzler AJ, Elce YA, Stone SG.A 13-year-old female Miniature Horse was evaluated for progressive unilateral exophthalmia of the left globe of 3 weeks' duration. Results: Results of a physical examination were unremarkable. Ophthalmic examination identified exophthalmus of the left globe with complete resistance to retropulsion and mild blepharoconjunctivitis. Computed tomography revealed a large, space-occupying mass within the left caudal maxillary and left conchofrontal sinuses. The mass extended into the left retrobulbar space and contacted the cribriform plate. Trephination yielded copious amounts of turbid yellow flui...
Characteristic of inflammatory airway disease in Japanese thoroughbred racehorses.
Journal of equine science    July 9, 2008   Volume 19, Issue 2 25-29 doi: 10.1294/jes.19.25
Kusano K, Ishikawa Y, Seki K, Kusunose R.Inflammatory airway disease (IAD) is a common cause of poor performance, interruption of training and premature retirement in racehorses. It is also reported that up to 80% of horses are affected at some point in the first years of training in UK and Australia. However, no studies with regard to the information on occurrence of IAD in Japanese Thoroughbred racehorses have been reported. To investigate the occurrence and the characteristics of IAD, epidemic research including endoscopic examination of the airway tract and trachea wash was conducted for Thoroughbred racehorses presenting coughs ...
Percutaneous endovascular retrieval of an intravascular foreign body in five dogs, a goat, and a horse.
Journal of the American Veterinary Medical Association    July 5, 2008   Volume 232, Issue 12 1850-1856 doi: 10.2460/javma.232.12.1850
Culp WT, Weisse C, Berent AC, Getman LM, Schaer TP, Solomon JA.CASE DESCRIPTION-5 Dogs, 1 goat, and 1 horse underwent percutaneous endovascular retrieval of intravascular foreign bodies between 2002 and 2007. CLINICAL FINDINGS-Foreign bodies were IV catheters in 4 dogs, the horse, and the goat and a piece of a balloon valvuloplasty catheter in 1 dog. Location of the foreign bodies included the main pulmonary artery (1 dog), a branch of a pulmonary artery (4 dogs), the right ventricle (the goat), and a jugular vein (the horse). TREATMENT AND OUTCOME-The procedure of percutaneous endovascular retrieval of the foreign body was easy to perform in all instance...
Equine giant cell tumor of soft parts: a series of 21 cases (2000-2007). Bush JM, Powers BE.In horses, giant-cell tumors of soft parts are rare neoplasms, with the majority of reported cases occurring within the hind limb muscles and soft tissues in older horses. The following article documents 21 cases of equine giant-cell tumors of soft parts clinically examined within the state of Colorado from 2000 to 2007. The majority of cases occurred in male horses aged 10 years or older. Nine (43%) arose within the hind limbs. Key histologic features included numerous multinucleated giant cells and hemosiderin-laden macrophages admixed with a spindle-cell proliferation. The majority demonstr...
Pharmacokinetics and clinical effects of pirfenidone administered intravenously in horses.
American journal of veterinary research    July 3, 2008   Volume 69, Issue 7 952-960 doi: 10.2460/ajvr.69.7.952
Braim AE, Macdonald MH, Bruss ML, Stanley SD, Giri JK, Giri SN.To characterize the plasma pharmacokinetics and clinical effects of pirfenidone administered IV in healthy horses. Methods: 6 adult horses. Methods: A 15 mg/kg dose of pirfenidone was administered IV over 5 minutes. Physical variables were recorded and blood samples collected prior to infusion; 2.5 minutes after beginning infusion; at the end of infusion; and at 3, 6, 9, 12, 15, 20, 25, 30, 40, 50, 60, 75, and 90 minutes and 2, 2.5, 3, 4, 6, 8, 12, and 24 hours after completion of infusion. Plasma concentrations of pirfenidone and its metabolites were determined. Results: Mild clinical effects...
Quantitative analysis of scintigraphic findings in tibial stress fractures in Thoroughbred racehorses.
American journal of veterinary research    July 3, 2008   Volume 69, Issue 7 886-890 doi: 10.2460/ajvr.69.7.886
Valdés-Martínez A, Seiler G, Mai W, Bolt DM, Mudge M, Dukti SA, Hubert JD.To develop a quantitative method of interpreting tibial scintigrams of Thoroughbred racehorses with tibial stress fractures that may facilitate diagnosis of fractures and to provide prognostic information regarding future performance of affected horses. Methods: 35 Thoroughbred racehorses. Methods: Static bone-phase scintigrams of tibial stress fractures were quantitatively analyzed by use of ratios of the mean radionuclide counts per pixel in a region of interest (ROI) drawn around the area of increased uptake of radiopharmaceutical to mean counts per pixel in a second ROI drawn around an app...
Eprinomectin treatment of psoroptic mange in hunter/jumper and dressage horses: a prospective, randomized, double-blinded, placebo-controlled clinical trial.
Veterinary parasitology    June 25, 2008   Volume 156, Issue 3-4 353-357 doi: 10.1016/j.vetpar.2008.06.018
Ural K, Ulutas B, Kar S.The purpose of this prospective, double-blinded, placebo-controlled clinical trial was to investigate the efficacy of topical eprinomectin for the treatment of psoroptic mange infestation in horses. 24 privately owned hunter/jumper and dressage horses were diagnosed with psoroptic mange infestation based on physical findings and skin scraping results were enrolled and randomly assigned to either topical eprinomectin pour-on solution (at a dose of 500microg/kg body weight weekly once for four applications) treatment group or a placebo group (purified water). Clinical evaluations and skin scrapi...
Surgical technique to repair grade IV rectal tears in post-parturient mares.
Veterinary surgery : VS    June 20, 2008   Volume 37, Issue 4 345-349 doi: 10.1111/j.1532-950X.2008.00387.x
Kay AT, Spirito MA, Rodgerson DH, Brown SE.To describe a surgical technique for repair of grade IV rectal tears after parturition in mares and to report outcome. Methods: Clinical report. Methods: Horses (n=6) with grade IV rectal tears. Methods: Mares were sedated and restrained in standing stocks. After caudal anesthesia and evacuation of feces from the rectum, the perineal region was aseptically prepared. Four stay sutures were placed through the external anal sphincter before vertical transection (12 o'clock). Caudal retraction of the tear was performed using Allis tissue forceps (5 mares) or stay sutures before accurate apposition...
Arthroscopic surgical approach and intra-articular anatomy of the equine suprapatellar pouch.
Veterinary surgery : VS    June 20, 2008   Volume 37, Issue 4 350-356 doi: 10.1111/j.1532-950X.2008.00388.x
Vinardell T, David F, Morisset S.To describe a direct arthroscopic approach to the suprapatellar pouch (SPP), its intra-articular anatomy, and report our clinical experience with SPP arthroscopy. Methods: (1) Experimental study and (2) retrospective clinical study. Methods: (1) Cadaveric equine hind limbs (n=24; 14 horses) and (2) 5 horses. Methods: Four femoropatellar joints (FPJ) were dissected or injected with latex to document surface landmarks and topographic anatomy. (1) Arthroscopic exploration of 20 SPP (10 equine cadavers) was performed and described, followed by dissection. (2) Medical records of horses that had FPJ...
Ultrasonographic diagnosis–idiopathic muscular hypertrophy of the small intestine in a miniature horse. Dechant JE, Whitcomb MB, Magdesian KG.No abstract available
Radiographic parameters for diagnosing sand colic in horses.
Acta veterinaria Scandinavica    June 13, 2008   Volume 50, Issue 1 17 doi: 10.1186/1751-0147-50-17
Kendall A, Ley C, Egenvall A, Bröjer J.Ingestion of sand can cause colic, diarrhoea and weight loss in horses, but these signs are unspecific and can have many other causes. The amount of sand that induces disease may vary between individuals. To avoid over-diagnosing, it is important to determine the amount of sand that can be found in horses without clinical signs of gastrointestinal disease. The aim of this study was to use previously suggested parameters for establishing a radiographic diagnosis of sand colic, and compare these findings between a sand colic group and a control group. Methods: Abdominal radiographs were obtained...
Severe alopecia areata and onychodystrophy on all four feet of a French trotter mare.
The Veterinary record    June 10, 2008   Volume 162, Issue 23 758-760 doi: 10.1136/vr.162.23.758
Bruet V, Degorce-Rubiales F, Abadie J, Bourdeau P.No abstract available
Electrochemotherapy in veterinary oncology.
Journal of veterinary internal medicine    June 10, 2008   Volume 22, Issue 4 826-831 doi: 10.1111/j.1939-1676.2008.0117.x
Cemazar M, Tamzali Y, Sersa G, Tozon N, Mir LM, Miklavcic D, Lowe R, Teissie J.Electropermeabilization is a method that uses electric field pulses to induce an electrically mediated reorganization of the plasma membrane of cells. Electrochemotherapy combines local or systemic administration of chemotherapeutic drugs such as bleomycin or cisplatin that have poor membrane permeability with electropermeabilization by direct application of electric pulses to the tumors. Preclinical studies have demonstrated excellent antitumor effectiveness of electrochemotherapy on different animal models and various tumor types, minimal toxicity, and safety of the procedure. Based on resul...
What is your diagnosis? Pleural fluid from a neonatal Thoroughbred filly with pneumonia.
Veterinary clinical pathology    June 7, 2008   Volume 37, Issue 2 237-241 doi: 10.1111/j.1939-165X.2008.00021.x
Stokol T, Gold J, Johnson A, Ainsworth D.A 3-day-old filly was presented to the Cornell University Hospital for Animals with an umbilical hematoma and mild aspiration pneumonia. The foal underwent abdominal surgery for resection of the hematoma. Recovery was uneventful, but 3 days after surgery, the foal became progressively tachypneic. Imaging studies revealed bilateral pleural effusion and pleuropneumonia. Cytologic evaluation and bacterial culture of the pleural fluid from both sides of the chest revealed sterile exudates, consisting mostly of neutrophils, with fewer macrophages and lymphocytes. Pleural fluid macrophages contained...
What is your diagnosis? Peritoneal fluid from an Arabian horse after colic surgery.
Veterinary clinical pathology    June 7, 2008   Volume 37, Issue 2 253-255 doi: 10.1111/j.1939-165X.2008.00022.x
Pratt SM, Christian JA, Paige Jackson L, Hawkins JF, Sojka JE.A 16-year-old castrated male Arabian horse was presented to the Purdue University Veterinary Teaching Hospital with a 4-hour history of colic. Initial examinations provided strong evidence for small intestinal obstruction. Abdominal surgery revealed a strangulating lipoma, and 25 feet of small intestine were resected. Postoperatively, the horse developed obstructive ileus due to adhesion formation, which required a second laparotomy. During and after surgery, the abdomen was lavaged with sodium carboxymethylcellulose (CMC). One week after the second surgery, evaluation of peritoneal fluid reve...
Evaluation of three methods for measurement of hemoglobin and calculated hemoglobin parameters with the ADVIA 2120 and ADVIA 120 in dogs, cats, and horses.
Veterinary clinical pathology    June 7, 2008   Volume 37, Issue 2 173-179 doi: 10.1111/j.1939-165X.2008.00039.x
Bauer N, Moritz A.Besides flow cytometric detection of cellular hemoglobin (HGB) concentration, the ADVIA 2120 uses a novel cyanide-free colorimetric method to determine extracellular total HGB concentration. In human samples, the results are equivalent to those of the cyanmethemoglobin method on the ADVIA 120. Cyanide-free HGB measurement has not been evaluated in animal samples. Objective: The aim of this prospective study was to compare the 3 methods of HGB analysis on the ADVIA 2120 and ADVIA 120 in blood samples from dogs, cats, and horses. Methods: Consecutive fresh K(3)EDTA blood samples from 119 dogs, 1...
Clinical and scintigraphic findings in horses with a bone fragility disorder: 16 cases (1980-2006).
Journal of the American Veterinary Medical Association    June 4, 2008   Volume 232, Issue 11 1694-1699 doi: 10.2460/javma.232.11.1694
Anderson JD, Galuppo LD, Barr BC, Puchalski SM, Macdonald MM, Whitcomb MB, Magdesian KG, Stover SM.To describe clinical and scintigraphic abnormalities in horses with a bone fragility disorder. Methods: Retrospective case series. Methods: 16 horses with scintigraphic evidence of multiple sites of increased radiopharmaceutical uptake (IRU). Procedures-Medical records were reviewed for information on signalment; history; clinical, clinicopathologic, and diagnostic imaging findings; and treatment. Follow-up information was obtained through telephone interviews with owners. Results: Horses ranged from 4 to 22 years old; there were 8 castrated males and 8 females. Foci of IRU most commonly invol...
Suspected transient pseudohypoaldosteronism in a 10-day-old quarter horse foal.
The Canadian veterinary journal = La revue veterinaire canadienne    June 3, 2008   Volume 49, Issue 5 494-498 
Arroyo LG, Vengust M, Dobson H, Viel L.A 10-day-old quarter horse colt was presented for signs of disorientation and inability to nurse. Hydronephrosis/hydroureters, with concomitant pyelonephritis and a severe electrolytes disturbance, were diagnosed. The clinical findings closely resembled those described for a syndrome of transient pseudohypoaldosteronism in human neonates. Un poulain Quarter horse âgé de 10 jours a été présenté pour des signes de désorientation et d’incapacité à se nourrir. Une hydronéphrose/hydrouretères avec pyélonéphrite concomitante et débalancement électrolytique sévère ont été diagno...
Prevalence of gastric ulcers in Thoroughbred broodmares in pasture: a preliminary report.
Veterinary journal (London, England : 1997)    June 3, 2008   Volume 181, Issue 3 251-255 doi: 10.1016/j.tvjl.2008.03.020
le Jeune SS, Nieto JE, Dechant JE, Snyder JR.Gastroscopic examinations were performed in 62 Thoroughbred broodmares (33 pregnant, 29 non-pregnant) at one breeding farm to investigate the prevalence of gastric ulceration. Age, pregnancy status, race earnings, last race start, herd size, medical history, number of live foals, breeding years, feed type and number of feedings were recorded, plus coat condition and body condition score were determined. Twenty-one mares were re-evaluated after foaling, and the foaling date, foal weight at birth and placenta weight were recorded. The overall prevalence of gastric ulcers was 70.9%, with a median...
Usability of normal force distribution measurements to evaluate asymmetrical loading of the back of the horse and different rider positions on a standing horse.
Veterinary journal (London, England : 1997)    May 27, 2008   Volume 181, Issue 3 266-273 doi: 10.1016/j.tvjl.2008.03.002
de Cocq P, Clayton HM, Terada K, Muller M, van Leeuwen JL.Pressure measurement devices in equine sports have primarily focused on tack (saddle pads and saddle fitting methods). However, saddle pressure devices may also be useful in evaluating the interaction and distribution of normal forces between the horse and rider, including rider position and riding technique. This study examined the validity, reliability, repeatability and possibilities of using a saddle pressure device to evaluate rider position. All measurements were performed using a standing horse. Validity was tested by calculating the correlation coefficient between measured normal force...
Evaluation of ‘Section-Ligation-Release (SLR)’ technique devised for castration in the stallion.
Reproduction in domestic animals = Zuchthygiene    May 27, 2008   Volume 43, Issue 6 678-684 doi: 10.1111/j.1439-0531.2007.00969.x
Saifzadeh S, Hobbenaghi R, Asri-Rezaei S, Shokouhi S J F, Dalir-Naghadeh B, Rohi S M.A novel technique [Section-Ligation-Release (SLR)] was evaluated for castration in the horse. Clinical traits, serum testosterone concentrations after challenge with human chorionic gonadotrophin (hCG), and histopathological changes of the testicular tissue were assessed. Five stallions, aged 24-48 months, were castrated using SLR technique under general anaesthesia. Both spermatic cords in each stallion were exposed at the scrotal neck by two 5-cm long incisions, followed by sharp dissection through the parietal vaginal tunic. Both vascular and non-vascular structures in the cords were triple...
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