Omneity® Pellets
All-In-One Vitamin & Mineral Pellet
Topic:Clinical Study
Clinical studies in equine research involve the systematic investigation of health and disease in horses through structured scientific methods. These studies aim to evaluate the safety and efficacy of treatments, understand disease mechanisms, and improve veterinary care practices. Clinical studies can include randomized controlled trials, observational studies, and case-control studies. They may focus on various aspects such as pharmacokinetics, therapeutic interventions, and diagnostic techniques. This page compiles peer-reviewed research studies and scholarly articles that explore the design, implementation, and findings of clinical studies in equine medicine, providing insights into their impact on horse health and veterinary practices.
Studies on the faecal egg output of horses after treatment with fenbendazole. Examination of faecal egg counts in horses and ponies has shown that after treatment with fenbendazole at dose levels of 7.5, 45 and 60 mg/kg, faeces remained free from strongyle eggs for periods of 6 to 18 weeks. The significance of these results is discussed in relation to routine anthelmintic treatment of horses. In particular, the activity of fenbendazole against mucosal stages of strongyle parasites allows for treatment to be recommended at less frequent intervals than when using other anthelmintics.
Chronic obstructive pulmonary disease (COPD): identification of affected horses. Mean normal values for PaO, and max A Ppl for horses were determined. Using 2 standard deviations below (Pa0,) and above (max A Ppl) the mean normal values as a guide, horses affected with COPD were satisfactorily distinguished from other horses in a series of 100 animals. The frequency of occurrence of 20 different clinical parameters in affected, not affected and possibly affected horses was examined statistically. Poor work performance and a history of previous febrile illness occurred more often in COPD horses than in others. The presence of a chronic cough, dyspnoea, double expiratory eff...
[Hippotherapy in multiple sclerosis (author’s transl)]. No abstract available
[Immunodiffusion serologic study of equine infectious anemia in the Province of Buenos Aires, Argentina]. Twenty seven per cent of 238 serum samples obtained from horses with clinical diagnosis were positive for the immunodifusion test, while 17% of the 452 sera obtained from asintomatic horses were positive. Twenty one per cent of the 870 sera studied were positive.
Artifact production with micromanometers used to record intracardiac pressure and sound. In horses experimental right and left heart catheterization using a catheter with two microtransducers 9 cm apart, usually in a transvalval position produced pressure and sound artifacts that confounded the diagnosis. Most were probably due to malpositioning resulting in movement through a valve during recording or impingement on the valve cusps or the chordae tendineae or lodgement in the apex of the heart. The recognition of these artifacts is particularly important in studies of large animals in which catheter siting cannot be monitored by radiography.
Isoelectric focusing of horse serum esterase isozymes and detection of new phenotypes. A new method for separating the isozymes of horse serum esterase is described. The improved resolution has enabled us to detect several previously undescribed phenotypes. This method has also been used to detect two different apparently 'silent' alleles.
Diagnosis of equine neurologic problems. This is a review of the more common diseases of the spinal cord and various areas of the brain of horses. The results of a two and one-half year study of spinal cord disease are emphasized. After a description of the lesion the salient clinical signs are described and the features that differentiate them from other similar diseases. In the seminar, films of case and slides of lesions will be shown to document these diseases.
[Diagnosis of infectious anemia in horses using the Coggins test]. Coggins' immune diffusion test was modified, and was applied as a screening one in the study of the epizootic status. The positive reactions were characterized by the production of a precipitation line between the antigen and the respective serum that was tested. The appearance of such a line was associated with that formed with the use of the positive control serum, pointing to a reaction of identity. With the weakly positive reactions the ends of the precipitin lines, formed with the use of the positive control serum, were found to deviate slightly toward the site where the antigen had been ...
Close linkage between the albumin and Gc loci in the horse. Evidence for close linkage between the structural loci for albumin and Gc protein in the horse was presented. A recombination frequency (c) of 0.009 +/- 0.006 (95% confidence limits: 0.001 less than c less than 0.032) was estimated. These results were based on a study of a large sire family comprising 223 offspring from informative matings. No evidence of linkage disequilibrium was observed in one horse population studied.
Evaluation of a pregnant mares’ serum and human chorionic gonadotrophin mixture for alleviating summer infertility in sows. A controlled on-farm trial was conducted to evaluate the effectiveness of a commercial gonadotrophin hormone mixture at overcoming a seasonal decrease in fertility in pigs in a sub-tropical environment (summer infertility). The average weaning to oestrus interval of the untreated sows was more than double that of the treated sows and this difference was highly significant. However, fewer of the treated sows farrowed and they produced smaller litters. The improvement in fertility in the treated group achieved by reducing the weaning to oestrus interval was more than cancelled out by an overall ...
The development of a radio-stethoscope for use in the horse at rest and during exercise. The development of a radio-stethoscope for horses is described. The equipment consisted of a sound transducer applied to the skin adjacent to the trachea and a radio transmitter attached to the saddle. The signals emitted were detected by telemetry and recorded on a magnetic tape-recorder. The recorder incorporated a monitor earphone so that sounds could be reproduced at the time of recording. The frequency response obtainable ranged from a few Hz to 4 KHz. This technique provided an objective means of studying the respiratory sounds generated during exercise although absolute values could not...
Proprioceptive innervation of the external cremaster muscle of some domestic mammals. The proprioceptive innervation of the external cremaster muscle of some domestic animals was studied. Muscle spindles and tendon organs with their well-known features were found, but this finding was uncommon and unexpected in the investigated animals. For this reason, we believe that there is no relationship between the presence of these proprioceptors and the cremasteric reflex.
Horner’s syndrome in the horse: experimental induction and a case report. The findings in 6 experimental and 1 natural case of Horner's Syndrome (HS) are presented. The experimental cases were induced by unilateral surgical section of the cervical sympathetic trunk in the middle third of the neck. The naturally occurring case was seen in a 17 year old gelding with a mediastinal tumour. The signs of HS in these horses included ptosis, miosis, enophthalmos, hemilateral sweating and temperature increase of the face and cranial cervical region on the affected side. The intensity of these signs was variable between and within animals. Miosis, enophthalmos and temperature...
The ‘normal range’ and precision of phytohaemagglutinin-induced equine lymphocyte transformation in vitro. Data are presented on lymphocyte transformation by phytohaemagglutinin in 20 normal horses. The logarithms of transformation ratios were found to have an approximately normal distribution, giving (for the transformation ratios themselves) a geometric mean of 23.6, a range of 1.92 to 97.3, and an estimated 95 per cent tolerance interval of 1.1 to 488. Analysis of variance on the logarithms of the transformation ratios gave a coefficient of variation of 140 per cent of the transformation ratios themselves for the variation between horses; whereas the coefficient of variation between duplicate sa...
