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Topic:Degenerative Joint Disease
Degenerative Joint Disease (DJD) in horses, also known as osteoarthritis, is a progressive condition characterized by the deterioration of joint cartilage and the underlying bone. This condition leads to pain, reduced mobility, and lameness in affected horses. DJD is typically caused by wear and tear on the joints, but it can also result from injury, infection, or developmental disorders. The disease primarily affects older horses, but younger horses can also be susceptible, especially if they have experienced joint trauma or abnormal joint stress. The diagnosis of DJD involves clinical evaluation, imaging techniques such as radiography or ultrasonography, and sometimes joint fluid analysis. This page compiles peer-reviewed research studies and scholarly articles that explore the pathophysiology, diagnosis, management, and treatment options for degenerative joint disease in equine patients.
A review of the salient features of osteochondrosis in the horse. There appears to be an increasing incidence of osteochondrosis in young fast-growing horses in Europe and the USA. The disease is thought to be congenital in type and affects endochondral ossification in growing bones. It can be localised to one joint or may be a generalised condition. The clinical manifestations of the disease lead to a secondary chronic degenerative joint disease in adult animals. There is a genetic predisposition to the condition which is associated with rapid growth and excessive high energy feeding. The careful genetic selection of bloodstock and restricted intake in earl...
Equine Allogeneic Chondrogenic Induced Mesenchymal Stem Cells Are an Effective Treatment for Degenerative Joint Disease in Horses. Degenerative joint disease is one of the main causes of equine early retirement from pleasure riding or a performance career. The disease is initially triggered by an abnormal loading of normal cartilage or a normal loading of abnormal cartilage. This primary insult is accompanied with joint inflammation, which leads to further progressive degeneration of the articular cartilage and changes in the surrounding tissues. Therefore, in search for an effective treatment, 75 adult horses with early signs of degenerative fetlock joint disease were enrolled in a randomized, multicenter, double-blinded...
