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Topic:Diagnosis

Diagnosis in horses involves the systematic identification of diseases and conditions affecting equine health. This process relies on a combination of clinical evaluations, laboratory tests, imaging techniques, and other diagnostic tools to assess the health status of horses. Veterinarians utilize these methods to identify symptoms, determine the underlying causes of health issues, and formulate appropriate treatment plans. Diagnostic procedures in equine medicine can include blood tests, ultrasound, radiography, endoscopy, and more specialized tests such as genetic screening or advanced imaging modalities like MRI and CT scans. This page aggregates peer-reviewed research studies and scholarly articles that explore various diagnostic techniques, their applications, and advancements in the field of equine veterinary medicine.
Plasma concentrations of endothelin-like immunoreactivity in healthy horses and horses with naturally acquired gastrointestinal tract disorders.
American journal of veterinary research    March 26, 2002   Volume 63, Issue 3 454-458 doi: 10.2460/ajvr.2002.63.454
Ramaswamy CM, Eades SC, Venugopal CS, Hosgood GL, Garza F, Barker SA, Moore RM.To compare plasma endothelin (ET)- like immunoreactivity between healthy horses and those with naturally acquired gastrointestinal tract disorders. Methods: 29 healthy horses and 142 horses with gastrointestinal tract disorders. Methods: Blood samples were collected from healthy horses and from horses with gastrointestinal tract disorders prior to treatment. Magnitude and duration of abnormal clinical signs were recorded, and clinical variables were assessed via thorough physical examinations. Plasma concentrations of ET-like immunoreactivity were measured by use of a radioimmunoassay for huma...
Septic flexor tendon core lesions in five horses.
Equine veterinary journal    March 22, 2002   Volume 34, Issue 2 213-216 doi: 10.2746/042516402776767286
Kidd JA, Dyson SJ, Barr AR.Intratendonous infection in the absence of any clinical evidence of a wound has not, to our knowledge, been described previously in horses. This paper reports the clinical features, diagnostic techniques. treatment and outcome in 5 cases of septic flexor tendon core lesions. This condition is characterised by seven lameness and ultrasonographic evidence of a central intratendonous anechoic core lesion which may enlarge rapidly.
Periocular neurofibrosarcoma in a horse.
Veterinary ophthalmology    March 22, 2002   Volume 4, Issue 4 237-241 doi: 10.1046/j.1463-5216.2001.00184.x
Strubbe DT.A periocular neurofibrosarcoma was debulked and treated with intralesional cisplatin in a 5-year-old Thoroughbred mare. The horse presented with a 1-year history of a large slowly progressing subcutaneous mass over the right supraorbital process. The mass was surgically debulked, and intralesional cisplatin (1.0 mg/cm3) was injected in 3 doses at 2 weeks, 5 weeks, and 8 weeks postoperatively. No recurrence was noted over a 15-month follow-up period. Histopathology of the mass indicated neurofibrosarcoma.
Spongiotic vesicular dermatitis as a cutaneous reaction pattern in seven horses.
Veterinary dermatology    March 22, 2002   Volume 12, Issue 5 291-296 doi: 10.1046/j.0959-4493.2001.00264.x
Hargis AM, Clark EG, Duclos DD, Leclerc S, West K.Over a 6-year period seven adult horses of different breeds and genders developed multifocal, exudative, oozing dermatitis characterized histologically by epidermal spongiotic vesicles and perivascular eosinophilic, neutrophilic and mixed mononuclear inflammation. Three horses were pruritic. Systemic disease was not noted. Two horses had a history of recurrent urticaria (hives) and one horse had nodules or welt-type lesions that progressed to exudative, oozing lesions. Interepithelial immunoglobulin (Ig)G was detected by avidin-biotin complex-peroxidase staining, but the pattern of staining wa...
Equine clinical cytogenetics–human chromosomes sitting on horse chromosomes.
Equine veterinary journal    March 21, 2002   Volume 34, Issue 2 110-111 doi: 10.2746/042516402776767141
Breen M.No abstract available
Detection of high circulating concentrations of inhibin pro- and -alphaC immunoreactivity in mares with granulosa-theca cell tumours.
Equine veterinary journal    March 21, 2002   Volume 34, Issue 2 203-206 doi: 10.2746/042516402776767196
Watson ED, Heald M, Leask R, Groome NP, Riley SC.No abstract available
Osteochondrosis of the second cervical vertebra of a horse.
Equine veterinary journal    March 21, 2002   Volume 34, Issue 2 210-212 doi: 10.2746/042516402776767169
Beck C, Middleton D, Maclean A, Lavelle R.No abstract available
Use of zoo-FISH to characterise a reciprocal translocation in a thoroughbred mare: t(1;1 6)(q16;q21.3).
Equine veterinary journal    March 21, 2002   Volume 34, Issue 2 207-209 doi: 10.2746/042516402776767295
Lear TL, Layton G.No abstract available
The effect of a pectin-lecithin complex on prevention of gastric mucosal lesions induced by feed deprivation in ponies.
Equine veterinary journal    March 21, 2002   Volume 34, Issue 2 195-198 doi: 10.2746/042516402776767268
Murray MJ, Grady TC.This study examined whether a product containing a pectinlecithin complex (Pronutrin) (1) could prevent gastric lesions induced in the equine gastric squamous epithelial mucosa using a protocol of intermittent feed deprivation that resulted in prolonged increased gastric acidity (Murray and Eichorn 1996). Eight ponies were used and served as their own controls in 2 trials in which there were 72 h cumulative deprivation (alternating 24 h with no feed, then 24 h free choice hay), with a 4-week interval between trials. Ponies were assigned randomly to receive either 250 g Pronutrin plus 200 g pel...
The use of magnetic motor evoked potentials in horses with cervical spinal cord disease.
Equine veterinary journal    March 21, 2002   Volume 34, Issue 2 156-163 doi: 10.2746/042516402776767204
Nollet H, Deprez P, Van Ham L, Verschooten F, Vanderstraeten G.The aim of this study was to investigate the use of magnetic motor evoked potentials as an ancillary diagnostic test in horses with cervical cord lesions. Transcranial magnetic stimulation was performed in 12 ataxic horses and the results of the evoked responses were compared to those found in normal horses. The latency and peak-to-peak amplitude of the potentials in the 12 ataxic horses were significantly different from those measured in normal horses. The configuration of the abnormal potentials was also polyphasic. Normalisation of the evoked potentials occurred in none of the horses, prese...
Sero types, phage types and antibiotic susceptibilities of Salmonella strains isolated from horses in The Netherlands from 1993 to 2000.
Veterinary microbiology    March 20, 2002   Volume 86, Issue 3 203-212 doi: 10.1016/s0378-1135(02)00007-x
van Duijkeren E, Wannet WJ, Heck ME, van Pelt W, Sloet van Oldruitenborgh-Oosterbaan MM, Smit JA, Houwers DJ.We studied 232 Salmonella strains from horses with salmonellosis in The Netherlands, isolated in the period from 1993 to 2000 in order to provide insight in the dynamics of sero-, phage types (pt) and antibiotic susceptibilities over time. The strains were tested for susceptibility to seven antimicrobial agents using the agar diffusion method. In addition, the isolates were sero typed and Salmonella enterica subspecies enterica Typhimurium and Enteritidis strains were further phage typed. S. Typhimurium strains of phage type 506 and 401 (both classified as DT 104 in the English phage typing sy...
Detection of antibodies to Borna disease virus (BDV) in Turkish horse sera using recombinant p40. Brief report.
Archives of virology    March 14, 2002   Volume 147, Issue 2 429-435 doi: 10.1007/s705-002-8331-8
Yilmaz H, Helps CR, Turan N, Uysal A, Harbour DA.The nucleoprotein of Borna disease virus (BDV-p40) was produced in a Baculovirus expression system using sf9 cells. The purity and specificity of the recombinant p40 was confirmed by SDS-PAGE and immunoblotting. The recombinant p40 was used in an ELISA to screen horse sera in Turkey. For this, 323 horses from selected cities in the Marmara region of Turkey were examined clinically and serum was collected from each. All horses were clinically healthy except for a few with wounds on the skin. Antibodies to BDV were detected in the sera of 82 (25%) of 323 horse sera. Six sera were selected that h...
Increased susceptibility of peripheral blood mononuclear cells to equine herpes virus type 1 infection upon mitogen stimulation: a role of the cell cycle and of cell-to-cell transmission of the virus.
Veterinary microbiology    March 13, 2002   Volume 86, Issue 1-2 157-163 doi: 10.1016/s0378-1135(01)00499-0
van der Meulen KM, Nauwynck HJ, Pensaert MB.Equine herpesvirus-1 (EHV-1) is an important pathogen of horses, causing abortion and nervous system disorders, even in vaccinated animals. During the cell-associated viremia, EHV-1 is carried by peripheral blood mononuclear cells (PBMC), mainly lymphocytes. In vitro, monocytes are the most important fraction of PBMC in which EHV-1 replicates, however, mitogen stimulation prior to EHV-1 infection increases the percentage of infected lymphocytes. The role of the cell cycle in viral replication and the role of cluster formation in cell-to-cell transmission of the virus were examined in mitogen-s...
Construction of a 5000(rad) whole-genome radiation hybrid panel in the horse and generation of a comprehensive and comparative map for ECA11.
Mammalian genome : official journal of the International Mammalian Genome Society    March 13, 2002   Volume 13, Issue 2 89-94 doi: 10.1007/s00335-001-2089-8
Chowdhary BP, Raudsepp T, Honeycutt D, Owens EK, Piumi F, Guérin G, Matise TC, Kata SR, Womack JE, Skow LC.A 5000(rad) whole-genome radiation hybrid (RH) panel was created for the horse. The usefulness of the panel for generating physically ordered maps of individual equine chromosomes was tested by typing 24 markers on horse Chromosome 11 (ECA11). The overall retention of markers on this chromosome was 43.6%. Almost complete retention of two of the typed markers--- CA062 and AHT44---clearly indicated the location of thymidine kinase gene on the short arm of ECA11. Seven of the typed markers were FISH mapped to align the RH and cytogenetic maps. With the RH-MAPPER approach, a physically ordered map...
A comparison of the mechanical strength of two stapled anastomosis techniques for equine small intestine.
Veterinary surgery : VS    March 9, 2002   Volume 31, Issue 2 104-110 doi: 10.1053/jvet.2002.31051
Bickers RJ, Blackford JT, Eiler H, Rohrbach B.To compare bursting strength, time of construction, and cost of a closed one-stage, stapled functional end-to-end jejunojejunostomy (FEE) with a stapled side-to-side jejunojejunostomy (STS). Methods: Experimental, randomized block design. Methods: Seven adult horses without gastrointestinal disease. Methods: The jejunum was isolated, and three FEE, three STS, and three control segments were created in each horse using a randomized block design. Anastomosis time was recorded. The intraluminal pressure at failure and mode of failure were recorded. Length at failure was measured on digitized imag...
Daily treatment of growing foals with equine somatotropin: pathologic and endocrinologic assessments at necropsy and residual effects in live animals.
Journal of animal science    March 8, 2002   Volume 80, Issue 2 392-400 doi: 10.2527/2002.802392x
Kulinski KM, Thompson DL, Capshaw EL, French DD, Oliver JL.This experiment assessed the effects of 12 mo of daily treatment of young horses with recombinant equine somatotropin (eST) on 1) carcass and internal organ traits at necropsy and 2) residual effects in live horses for 60 d after cessation of treatment. Seven horses received eST daily at 20 microg/kg BW; seven others received vehicle (controls). Four horses from each group were killed at the end of treatment. There were few effects of eST treatment on hematologic assessments or histopathologic evaluations of internal organs. Treatment with eST increased the weights of the right adrenal gland (...
Characterization of monoclonal antibodies developed against Sarcocystis neurona.
Parasitology research    March 8, 2002   Volume 88, Issue 6 501-506 doi: 10.1007/s00436-002-0602-y
Marsh AE, Hyun C, Barr BC, Tindall R, Lakritz J.Equine protozoal myeloencephalitis (EPM), caused by a protozoal parasite infection of the central nervous system, is the most commonly diagnosed neurologic disease of horses in North America. In specific regions of the United States approximately 50% of the horse population is seropositive to Sarcocystis neurona. However, not all seropositive horses develop clinical signs. Detailed clinical examination, along with cerebrospinal fluid antibody evaluation are often used to diagnose EPM. Postmortem evaluation of the brain stem and spinal cord for histopathologic lesions compatible with nonsuppura...
Seasonal dynamics of ticks (Acari: Ixodidae) on horses in the state of São Paulo, Brazil.
Veterinary parasitology    March 7, 2002   Volume 105, Issue 1 65-77 doi: 10.1016/s0304-4017(01)00649-5
Labruna MB, Kasai N, Ferreira F, Faccini JL, Gennari SM.Natural tick infestations were assessed every 14 days on horses over a 2-year period. Amblyomma cajennense adult ticks were counted individually, without detachment from the horses. Larvae and nymphs of A. cajennense were collected using a rubber scraper that scratched engorged immature ticks from the host. Adult females of Anocentor nitens larger than 4mm length were counted on the horses. Blood samples were also obtained from the horses every 14 days and macroclimatic data were obtained for the study period. Infestations of A. cajennense demonstrated distinct peaks of activity for each of th...
5-Hydroxytryptamine mediated contractions in isolated preparations of equine ileum and pelvic flexure: pharmacological characterization of a new 5-HT(4) agonist.
Journal of veterinary pharmacology and therapeutics    March 5, 2002   Volume 25, Issue 1 49-58 doi: 10.1046/j.1365-2885.2002.00380.x
Weiss R, Abel D, Scholtysik G, Straub R, Mevissen M.The effects of 5-hydroxytryptamine (5-HT), HTF 919, a new 5-HT(4) agonist, and the antagonists SB 203-186 (5-HT(4)) and tropisetron (5-HT(3)) on intestinal motility were tested in vitro on isolated preparations of horse ileum and pelvic flexure. Concentration-response curves were created by cumulative application of the agonists with or without preincubation of the antagonists. The 5-HT preparation induced a concentration-dependent contraction in equine ileum and pelvic flexure. The results indicate that 5-HT receptors are present in all parts of equine intestine investigated in this study. Tr...
Isolation and characterization of two European strains of Ehrlichia phagocytophila of equine origin.
Clinical and diagnostic laboratory immunology    March 5, 2002   Volume 9, Issue 2 341-343 doi: 10.1128/cdli.9.2.341-343.2002
Bjöersdorff A, Bagert B, Massung RF, Gusa A, Eliasson I.We report the isolation and partial genetic characterization of two equine strains of granulocytic Ehrlichia of the genogroup Ehrlichia phagocytophila. Frozen whole-blood samples from two Swedish horses with laboratory-verified granulocytic ehrlichiosis were inoculated into HL-60 cell cultures. Granulocytic Ehrlichia was isolated and propagated from both horses. DNA extracts from the respective strains were amplified by PCR using primers directed towards the 16S rRNA gene, the groESL heat shock operon gene, and the ank gene. The amplified gene fragments were sequenced and compared to known seq...
Fusion of the distal sesamoid and distal phalanx in a yearling colt.
The Veterinary record    March 2, 2002   Volume 150, Issue 5 143-146 doi: 10.1136/vr.150.5.143
Riccaboni P, Di Giancamillo M, Leonardi L, Di Giancamillo A, Cammarata G.This paper describes a rare malformation of the distal portion of the left foredigit of a 15-month-old half-bred colt which was severely lame. Radiological, pathological and tomographic studies revealed hypoplasia of the metacarpophalangeal skeleton, absence of the distal sesamoid and deformation of the distal phalanx. Morphological analysis of the lesion and computerised measurement of the width of the articular surface of the distal phalanx suggested an early fusion between the distal sesamoid and distal phalanx.
An unusual case of upper respiratory obstruction in a horse. Terry C, Shumpert K, Rashmir-Raven AM, Pool R.No abstract available
Looking for the pony in the HERS data. Heart and Estrogen/progestin Replacement Study.
Circulation    February 28, 2002   Volume 105, Issue 8 902-903 
Barrett-Connor E.No abstract available
A lipoma of the extensor tendon sheaths in a horse. Hammer EJ, Chope K, Lemire TD, Reef VB.This report describes the identification and surgical removal of a lipoma from the extensor tendon sheaths of a horse. To the authors' knowledge, this is the first report of a lipoma of the extensor tendon sheaths of a horse. Ultrasonographic evaluation was crucial to patient management, providing information regarding the soft tissue mass characteristics, tumor margins and synovial involvement prior to surgical exploration. Surgical removal was performed and was curative.
[Botulism in a horse: a concrete possibility in the Netherlands?].
Tijdschrift voor diergeneeskunde    February 23, 2002   Volume 127, Issue 3 82 
Goehring LS, Sloet van Oldruitenborgh-Oosterbaan MM.No abstract available
Detection of Sarcocystis neurona antibodies in French horses with neurological signs.
International journal for parasitology    February 19, 2002   Volume 32, Issue 4 481-485 doi: 10.1016/s0020-7519(01)00370-8
Pitel PH, Pronost S, Gargala G, Anrioud D, Toquet MP, Foucher N, Collobert-Laugier C, Fortier G, Ballet JJ.No abstract available
Rejection of MITF and MGF as the genes responsible for appaloosa coat colour patterns in horses.
Animal genetics    February 19, 2002   Volume 33, Issue 1 82-84 doi: 10.1046/j.1365-2052.2002.0742h.x
Terry RB, Bailey E, Lear T, Cothran EG.No abstract available
Rapid immunohistochemical detection of Rhodococcus equi in impression smears from affected foals on postmortem examination.
Journal of veterinary medicine. B, Infectious diseases and veterinary public health    February 16, 2002   Volume 48, Issue 10 751-758 doi: 10.1046/j.1439-0450.2001.00505.x
Szeredi L, Makrai L, Dénes B.The first objective of this study was to develop an immunohistochemical procedure for rapid detection of Rhodococcus equi in impression smears from affected organs of foals on postmortem examination. The second aim was to demonstrate whether R. equi can be detected in smears of tracheal exudates collected from the same foals using an immunohistochemical method. Impression smears and cryostat and paraffin-embedded sections were made from the lungs and mediastinal lymph nodes of three foals (A, B and C) that had died of respiratory disease caused by R. equi, and also from the caudal mesenteric l...
Evaluation and treatment of an adult quarter horse with an unusual fracture of the humerus and septic arthritis.
The Canadian veterinary journal = La revue veterinaire canadienne    February 15, 2002   Volume 43, Issue 2 120-122 
Mitchell C, Riley CB.Humeral fractures are rare and usually carry a guarded prognosis in adult horses. This paper describes the evaluation and the successful surgical management of a fracture of the lateral supracondyloid crest and part of the epicondyle of the humerus in an adult quarter horse.
Perirectal abscess, colic, and dyschezia in a horse.
The Canadian veterinary journal = La revue veterinaire canadienne    February 15, 2002   Volume 43, Issue 2 127-128 
Torkelson J.A quarter horse gelding with intermittent colic was diagnosed with a perirectal abscess and dyschezia. Rectal ultrasonography identified a multiloculated, fluid-filled mass. A perirectal abscess was diagnosed when the mass ruptured and drained into the rectum. The abscess was treated successfully with warm soapy water enemas and trimethoprim and sulfamethoxazole.