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Topic:Disease Diagnosis
Disease diagnosis in horses involves the identification and characterization of illnesses through various diagnostic methods and tools. This process is essential for effective veterinary care and management of equine health. Techniques used in diagnosing diseases in horses include clinical examinations, laboratory tests, imaging modalities such as ultrasonography and radiography, and molecular diagnostics. Blood tests are frequently utilized to assess parameters such as complete blood count and biochemical profiles, which can indicate underlying health issues. Additionally, advancements in genetic testing and biomarker identification have enhanced the ability to detect specific diseases early. This page aggregates peer-reviewed research studies and scholarly articles that explore diagnostic methodologies, their applications, and their impact on equine health management.
Spatial vector changes during ventricular depolarisation using a semi-orthogonal lead system–a study of 190 cases. The paper describes the spatial vector changes during ventricular depolarisation in 190 horses using a semi-orthogonal ECG lead system. The replacement of planar vector loops by a plot of 3 parameters to depict the changing spatial vector, with a time base on the X axis, is described and illustrated. Some horses with diastolic murmurs and some with a history of respiratory problems formed 2 distinct groups. As a result of these findings a possible relationship between the vector changes and the anatomical siting of the ventricles is suggested and discussed. Attention is drawn to certain measur...
Identification of allergens in extract of horse hair and dandruff by means of crossed radioimmunoelectrophoresis. Sera from 26 patients and 4 normals were examined for specific IgE binding to antigens of extract of horse hair and dandruff by means of CRIE. 22 of the patients were RAST- and intracutaneous-positive to horse extract. 4 more of the patients were RAST-negative to horse allergens, but showed allergies to extract of allergens from sources other than horse. The remaining four sera from controls were RAST-negative to horse and had no history of allergy. Antigens of horse hair and dandruff showed a significantly higher degree of binding to specific IgE in the sera from the first group of patients t...
Agammaglobulinemia in a horse with evidence of functional T lymphocytes. Agammaglobulinemia was diagnosed in a 1-year-old Thoroughbred horse on the basis of the following observations: (1) absence of serum immunoglobulins M, A, and G(T); (2) small amounts of serum immunoglobulin G (16 mg/100 ml); (3) absence of specific antibody in the serum of the horse following immunization and challenge exposure to 2 antigens; (4) absence of plasma cells, primary follicles, and germinal centers in a lymph node removed after antigenic stimulation; (5) absence of "natural" serum antibodies to rabbit-erythrocytes which were easily detectable in age-matched control horse serums; an...
Suppression of synthesis of an IgG subclass in a persistent viral infection. Comparison of immunoglobulin levels of nine horses before and after infection with equine infectious anaemia (EIA) virus demonstrated a significant depression of serum IgG(T) at 2 months (P less than 0-001) and at 1 year (P less than 0-01) after infection. In contrast, the levels of IgGa were significantly increased at both times after infection. Another sixteen horses with EIA for 1-4 months were examined and there was also significant depression (P less than 0-001) of IgG(T) when compared to pre-infection levels. No significant changes in IgG(T), IgGa and IgM were noted in fourteen normal ho...
Tumours of the prostate and penis. Tumours of the male genital tract, excluding the testes, are relatively rare in the six major domestic animals. The most important tumours are prostate carcinoma and transmissible venereal tumour of the penis in dogs, fibropapilloma of the penis in bulls, squamous papilloma and squamous cell carcinoma in horses, and squamous papilloma in pigs. Four histological types of canine prostate carcinoma exist: alveolar papillary, acinar, organoid, and poorly differentiated. The biological behaviour of prostate carcinomas is similar to that in man, with frequent metastasis to the regional pelvic nodes,...
Oxibendazole: critical anthelmintic trials in equids. The efficacy of oxibendazole against gastrointestinal parasites of horses was evaluated by the critical test method. Naturally infected ponies of various ages were given single oral doses of 5, 10, or 15 mg-kg of bodyweight. The drug was highly effective against adult large strongylids (Strongylus vulgaris, S edentatus, S equins), adult small strongylids (especially species of the genera Cylicostephanus, Cylicocyclus, Cyaathostomum, and Triodontophorus), and adult and larval stages of the large pinworm, Oxyuris equi. There was no apparent dose-related differences in efficacy. Oxibendazole was ...
Calf blood extract in treatment of equine foot lesions. A deproteinized calf blood extract (Solcoseryl: Solco Basle, Ltd, Switzerland) enhanced healing of induced and naturally-occurring lesions in the feet of 30 horses and donkeys.
Hereditary multiple exostosis. A comparative genetic evaluation in man and horses. Comparative studies are being conducted on hereditary multiple exostosis in man and the horse. In both, there is an unquestionable inheritance pattern of a typical single, dominant, autosomal gene. Those who carry the gene have a one-half chance of transmitting it to each offspring, whereas, those who do not carry the gene do not transmit this abnormality to their progeny. The lesions are clinically and histologically similar; no persistent chromosomal irregularities have been associated with the abnormality in either man or the horse and no single evidence of malignancy in either man or anima...
Monocyte activation in horses persistently infected with equine infectious anemia virus. The monocytes of horses infected with equine infectious anemia virus were shown by their failure to migrate from capillary tubes and their increased adherence to erythrocytes to be activated.
Occurrence of second and third instars of Gasterophilus intestinalis and Gasterophilus nasalis in stomachs of horses in Kentucky. The occurrence of 2nd and 3rd instars of Gasterophilus intestinalis and Gasterophilus nasalis was determined in 476 horses during the 22-year period from 1951 to 1973. Overall, G intestinalis infected 98.7% of the horses and averaged 168/horse; whereas G nasalis infected 80.7% of the horses and averaged 52/horse. Aggregate average total numbers for G intestinalis ranged from a low of 50 in September to a high of 229 in March, and for G nasalis, from a low of 14 in September to a high of 82 in February. Horses were infected by 2nd or 3rd instars of both species on a year-round basis. Differenti...
