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Topic:Disease Treatment
Disease treatment in horses encompasses a range of medical interventions and management strategies aimed at addressing various health conditions affecting equine species. These treatments can include pharmacological approaches, such as the administration of antibiotics, anti-inflammatory drugs, and antiparasitic medications, as well as non-pharmacological methods like physical therapy, dietary adjustments, and surgical procedures. The selection of appropriate treatments depends on the specific disease, its severity, and the individual needs of the horse. This topic brings together peer-reviewed research studies and scholarly articles that explore the efficacy, safety, and advancements in therapeutic options for equine diseases, providing insights into best practices and emerging trends in equine veterinary medicine.
Clinical trial of xylazine with ketamine in equine anaesthesia. One hundred anaesthetics were administered in a clinical trial to 95 equine patients, ranging in age from nine months to 19 years and in weight from 140 to 1270 kg, undergoing a variety of surgical procedures. Acepromazine maleate premedication (0.01 to 0.03 mg per kg intramuscularly) was given to seven animals, the remainder were not premedicated. Xylazine (1.1 mg per kg) was injected intravenously over a two minute period and after a pause of two minutes ketamine (2.2 mg per kg) was injected rapidly by the same route. For 30 procedures no other anaesthetic was given but in 59 cases anaesthes...
Haloxon: critical tests of antiparasitic activity in equids. Critical tests were conducted in 14 naturally infected equids (13 horses and 1 pony) to evaluate the antiparasitic activity of haloxon. Single doses were administered by stomach tube to 3 horses and 1 pony (60 mg/kg of body weight), by addition to the feed of 3 horses (60 mg/kg), and intraorally by powder gun to 7 horses (65 mg/kg). Haloxon was efficacious (99% to 100%) against infections of Parascaris equorum, Oxyuris equi (mature and immature), and Strongylus vulgaris at both dosage levels. Probstmayria vivipara parasites were removed in 1 horse treated at 60 mg/kg by stomach tube and S equi...
Controlled tests of ivermectin against migrating Strongylus vulgaris in ponies. Twelve pony foals were reared worm-free and inoculated with Strongylus vulgaris. On day 7 after inoculation, 6 ponies were given ivermectin IM at a dose of 200 micrograms/kg of body weight and on day 28 were necropsied. Ivermectin was effective in eliminating early 4th-stage S vulgaris larvae and reducing clinical signs associated with acute arteritis. After administrative ivermectin was effective against early 4th-stage Strongylus vulgaris larvae in ponies when administered at 100, 300, or 800 micrograms/kg of body weight. The purpose of the present study was to report on a more extensive tri...
A comparative study of the toxicity of Fusarium verticillioides (= F. moniliforme) to horses, primates, pigs, sheep and rats. An isolate of Fusarium verticillioides (MRC826) that induced experimental leukoencephalomalacia, also caused acute toxicity when fed to pigs and administered per rumen fistula to sheep. Pigs developed severe pulmonary oedema while sheep manifested severe nephrosis and hepatosis. A less toxic isolate (F. verticillioides MRC602), fed to baboons, resulted in acute congestive heart failure or hepatic cirrhosis, depending on the dose. Both isolates were toxic to rats and caused similar lesions, namely, hepatic cirrhosis and intraventricular cardiac thrombosis.
Anthelmintic efficacy fenbendazole paste in equines. A single oral dose of fenbendazole (FBZ) paste at 7,5 mg/kg body mass was given to 5 horses. It was highly effective against adults of the following genera: Cyathostomum, Cylicostephanus, Cylicondontophorus, Poteriostomum, Cylicocyclus, Triodontophorus, Oesophagodontus (and other genera belonging to the subfamily Cyathostominae). Similarly, high efficacy was obtained against the adults of the following species: Oxyuris equi, Strongylus vulgaris, Strongylus equinus and Probstmayria vivipara. These results were confirmed in 12 horses and in addition FBZ at 7,5 mg/kg was highly effective against ...
Tioxidazole: evaluation of antiparasitic activity of a micronized formulation in horses by the critical test method. Antiparasitic activity of a micronized formulation of the benzothiazole compound, tioxidazole, at the dose rate of 11 mg/kg, was evaluated by the critical test method. Drug was given by stomach to 3 horses and on feed to 3 horses. Excellent removal activity was found for Strongylus vulgaris (100%) in 5 naturally infected horses, S edentatus (91% to 100%) in 5 horses, small strongyles (88% to 99%) in 6 horses, immature Oxyuris equi (100%) in 5 horses, and Parascaris equorum (100%) in 5 horses (a 6th horse had 10 small specimens present at necropsy). There was no measurable activity against bots...
Decalcified bone grafts in the horse. The need for early postoperative weight bearing following fracture repair in the horse has led to investigation of various means of expediting the healing process. Bone grafting represents one means of accomplishing this, and the transplantation of autologous tissues has proven to be most useful in equine orthopedics. Acid-decalcified, frozen, allogeneic bone for grafting is easy to prepare, readily contoured, osteogenic, and elicits no obvious immune or rejection response. The most compelling reason for the use of the substance is the elimination of the need of a harvesting operation on a pat...
Surgical technique and considerations for implantation of electromagnetic blood flow transducer and occluder onto the coronary arteries. A technique was developed for the implantation of an electromagnetic flow probe and vascular occluder onto the right and left coronary arteries in the calf and pony. Surgical manipulation was well tolerated in the animals. The subcutaneous housing on the peripheral ends of these devices of the lateral thoracic wall served as a maintenance-free technique for chronic exteriorization of these devices. Implantation onto the coronary arteries required a surgical technique which accomplished the prerequisites for proper flow probe function. A reactive hyperemic response was elicited in each animal b...
A simple treatment for “rye-grass staggers”? Sir,—A series of happy coincidences (serendipity?) has led us to a simple treatment which seems to have successfully alleviated symptoms of “rye-grass staggers” in a horse, a calf and two badly affected sheep. Although primarily engaged in a search for the causative agent(s) of rye-grass staggers, casual conversations with people having long experience of this disorder revealed many interesting observations. One of these was a racing-stable remedy for rye-grass staggers, which was the administration of “a couple of handfulls” of Epsom salts in a bran mash, with as much puha (Sonchus ...
