Omneity® Pellets
All-In-One Vitamin & Mineral Pellet
Topic:Disease Treatment
Disease treatment in horses encompasses a range of medical interventions and management strategies aimed at addressing various health conditions affecting equine species. These treatments can include pharmacological approaches, such as the administration of antibiotics, anti-inflammatory drugs, and antiparasitic medications, as well as non-pharmacological methods like physical therapy, dietary adjustments, and surgical procedures. The selection of appropriate treatments depends on the specific disease, its severity, and the individual needs of the horse. This topic brings together peer-reviewed research studies and scholarly articles that explore the efficacy, safety, and advancements in therapeutic options for equine diseases, providing insights into best practices and emerging trends in equine veterinary medicine.
Susceptibility of Haemophilus equigenitalis, the causal agent of contagious equine metritis, to 31 antimicrobial agents. The minimal inhibitory concentrations of 31 antimicrobial agents were determined for 99 isolates of Haemophilus equigenitalis by the agar dilution method. All the isolates showed good susceptibility to 26 antimicrobial agents tests, minimal inhibitory concentrations of which were less than 3.13 micrograms/ml for more than 90% of the isolates. Of these agents, 4 macrolides (erythromycin, oleandomycin, kitasamycin, tylosin), 3 tetracyclines (tetracycline, chlortetracycline, oxytetracycline), 1 peptide (colistin), 1 penicillin (ampicillin) and 1 pleuromutilin (tiamulin) were the most active agent...
Serum levels of amoxycillin following its oral administration to thoroughbred foals. Amoxycillin trihydrate was administered orally to 6 foals at dose rates of 13 mg/kg (low), 20 mg/kg (medium) and 30 mg/kg (high) and serum concentrations determined at intervals up to 8 h. Therapeutic serum levels of 1 microgram/ml persisted for 268 mins at a dose rate of 13 mg/kg, for 339 mins at 20 mg/kg and for 381 mins at 30 mg/kg. A 2 micrograms/ml serum level persisted for 198 mins at a dose rate of 13 mg/kg, for 268 mins at 20 mg/kg and for 311 mins at 30 mg/kg. To determine the spectra of its antibacterial activity, the minimum inhibitory concentrations of amoxycillin against 8 genera ...
A survey of post mortem findings in 480 horses 1958 to 1980: (2) disease processes not directly related to the cause of death. Disease processes not directly related to the cause of death recorded in 480 consecutive post mortem examinations of horses performed at the department of pathology, Veterinary Field Station, University of Liverpool, between February 1958 and February 1980 are reported. The alimentary, cardiovascular, respiratory and locomotor systems were those most frequently diseased. The most common specific entities were those associated with endoparasitism and its associated vascular lesions, pneumonia and fractures.
A physiological approach to fluid and electrolyte therapy in the horse. In this article a physiological approach to fluid therapy is discussed, commencing with examination of fluid distribution in the normal horse. The functions of individual plasma electrolyte concentrations are considered and practical causes of acid-base disturbances discussed. When fluid administration is necessary, selection of the route for fluid administration as well as the type of fluid are important considerations and these must be adjusted to the needs of the individual case. Balanced polyionic solutions appear to be most suitable for general use because normal saline can produce hypoka...
Contagious equine metritis: effect of vaccination on control of the disease. Pony mares were vaccinated with killed contagious equine metritis (CEM) bacteria by IV, subcutaneous, and intrauterine (IU) routes (or a combination of these routes). The serum agglutinating antibody titer varied from 1:64 to 1:1,024 after vaccination. In pony mares challenge exposed with 96-hour-old culture of CEM bacteria given by IU route, there were clinical signs of CEM, but these signs were less severe in vaccinated mares than in nonvaccinated mares. The bacterium was isolated for the exudate and from uterine samples collected from the mares after challenge exposure. A low titer of IU an...
Distribution of ribonucleic acid coliphages in animals. To determine the distribution pattern of ribonucleic acid (RNA) coliphages (classified by serological groups I through IV) in animal sources, we isolated RNA phages from (i) feces samples from domestic animals (cows, pigs, horses, and fowls), some other animals in a zoological garden, and humans, (ii) the gastrointestinal contents of cows and pigs, and (iii) sewage samples from treatment plants in slaughter houses. These samples were then analyzed serologically. The concentration of RNA phages in the first and second kinds of material was fairly low (10 to 10(3) plaque-forming units per origin...
[Contagious equine metritis 1977 (CEM). A review (author’s transl)]. The properties of the bacterium, symptoms, post-mortem findings, diagnosis, therapy, control, prevention and epizootiology of contagious equine metritis 1977 (CEM) are reviewed. This disease was previously diagnosed in most of the countries surrounding the Netherlands, but has not been reported so far in the Netherlands. On the analogy of the serum adopted in other countries, a code of practice was developed to prevent and control this disease when it is diagnosed.
Therapeutic effect of phenylbutazone on experimental acute Escherichia coli endotoxemia in ponies. Phenylbutazone (PBZ), a classic anti-inflammatory and prostaglandin-synthesis inhibitor drug, was used to determine the role of prostaglandins and other mediators on the development and perpetuation of the response to intraperitoneal Escherichia coli endotoxin administration. The PBZ (15 mg/kg of body weight) was administered IV 30 minutes after endotoxin administration and was repeated later at 6 and 12 hours at a dose of 10 mg/kg. A variety of evaluation measurements (hematologic, blood glucose, pyruvate, lactate and fibrinogen, serum beta-glucuronidase, prothrombin time, blood gases, hepati...
[Disseminated intravascular coagulation in colitis X. Coincidence or part of the syndrome? (author’s transl)]. The course run by the disease is described in a horse which showed the symptom complex of colitis X following treatment with oxytetracycline. Disseminated intravascular coagulation was also observed in this horse. The possibility of disseminated intravascular coagulation being part of colitis X is discussed.
[Some clinical biochemical features of ‘tying up’ in horses (author’s transl)]. The changes in the activities of lactate dehydrogenase (LDH) and creatine phosphokinase (CPK) in de blood of thirty-three horses with 'tying up' were compared. The extent to which the serum enzymes LDH, CPK and glutamic oxaloacetic transaminase (GOT) and the changes in the activities of these enzymes after suitable labour can be used in the diagnosis of 'tying up' and in following the recovery of patients was studied.
Sodium hyaluronate in equine traumatic arthritis. Thirty seven intra-articular injections, each 2 ml sodium hyaluronate were made into 21 arthritic joints in 15 racing Thoroughbreds and one part-bred polo pony. One joint failed to improve at all, 16 became sound with one injection, 4 became sound with 2 injections, and 11 joints showed various degrees of response. Eleven of 14 horses became sound for flat racing. Discussion relates to the technique of using sodium hyaluronate, some clinical and pathological aspects of traumatic arthritis, joint lubrication and a brief review of some properties of sodium hyaluronate which have a bearing on art...
Warfarin anticoagulation in the horse. The hematologic and clinical effects of anticoagulation with warfarin were documented in 4 horses. All of the animals had thrombophlebitis (external jugular vein). Measures of coagulation were monitored, with a prothrombin time of 1.5 to 2.5 x base-line value being used as the effective range of anticoagulation. Recanalization was achieved in 2 of 4 cases. Hemorrhage, both subcutaneous and through a surgical incision, was a complication. Vitamin K1, an antidote to warfarin toxicosis, was administered intravenously to reverse anticoagulation and to control hemorrhage.
A critical efficacy test of cambendazole in equids: the use of the geometric means to assess efficacy. The anthelmintic efficacy of a 44.5% paste formulation of cambendazole was evaluated in a critical trial performed on 5 horses and a donkey. A dosage of 20 mg/kg showed reduction of mean parasite burdens as follows: Strongylinae greater than 99%; Cyathostominae 94%; immature and adult Oxyuris equi 89 and greater than 99%; Probstmayria vivipara greater than 99% and Habronema muscae 97%. Parascaris equorum and Anoplocephala perfoliata were present in small numbers in individual animals only, and while all were removed by treatment, the small numbers did not justify calculation of a percentage ef...
Equine pyelonephritis and unilateral nephrectomy. The clinical and laboratory findings of illness in a 2-year-old Thoroughbred filly are described. The treatment employed, including unilateral nephrectomy, and the macro- and microscopic findings in the diseases kidney are presented and this rare case is discussed briefly.
Recovery of peripheral chemoreceptor function after denervation in ponies. Resting ventilation (PaCO2) and ventilatory responses to acute hypoxia and to intravenous NaCN were assessed over a 4-yr period following cutting of the carotid sinus nerves and stripping the adventitia of the aortic arch. The data indicated essentially complete loss of peripheral chemoreceptor function immediately after surgery and hypoventilation during normoxia (delta PaCO2 = +8.7 Torr). There was a time-dependent, partial recovery of peripheral chemoreceptor function between 2 and 22 mo after surgery. Approximately 10% of the ventilatory response to iv NaCN returned, and 30-40% of the norm...
Criteria for development of animal models of diseases of the respiratory system: the comparative approach in respiratory disease model development. Advances in the understanding of human respiratory disease can come from careful clinical studies of the diseases as they occur in man, but such studies are naturally limited in terms of experimental manipulation. In the last 2 decades, an increasingly complex plethora of experimental respiratory disease models has been developed and utilized by investigators, but relatively less attention has been paid to the naturally occurring pulmonary diseases of animals as potential models. This paper is aimed at presenting selected examples of spontaneous pulmonary disease in animals that may serve as e...
Anthelmintic efficiency of fenbendazole in equines. A single oral dose of fenbendazole (FBZ) at 10mg/kg body mass was given to 5 donkeys. A further 5 donkeys were dosed with a medicated lick (1 mg FBZ/g lick) until the oral consumption was 10mg/kg body mass. In both trials FBZ was highly effective against adults of the following genera: Cyathostomum, Cylicocyelus, Cylicostephanus, Cylicodontophorus, Poteriostomum, Cabellonema, Craterostomum and Triodontophorus; similarly high efficiency was obtained against the following species: Habronema majus, Habronema musca, Strongylus vulgaris and Oxyuris equi and worms identified as belonging to the subf...
In vitro susceptibility of Haemophilus equigenitalis, the causative organism of contagious equine metritis 1977, to antimicrobial agents. The in vitro susceptibility of recent clinical isolates of Haemophilus equigenitalis to various antimicrobial agents was determined by the disk diffusion test and the World Health Organization-International Collaborative Study agar dilution procedure. Ampicillin and tetracycline were the most active drugs. All strains were susceptible to beta-lactam antibiotics, chloramphenicol, trimethoprim-sulfamethoxazole, nalidixic acid, nitrofurantoin (Furadantin), and bacitracin. All but two strains were resistant to streptomycin, whereas all strains were susceptible to the other aminocyclitol antibodies...
Rectal prolapse in the horse. Eleven horses with rectal prolapses were examined at Purdue University. Nine of the 11 prolapses were corrected by submucosal resection. Four of those were treated by a modified submucosal resection that apposes mucosa as well as submucosa. Follow-up of 8 cases, at intervals ranging from 4 months to 6 years, established that rectal prolapse did not recur following the resection.
Effects of denervation of the digit of the horse. A study was conducted in an effort to explain why digital necrosis sometimes follows neurectomy in the horse. Six horses were subjected to unilateral section of the medial and lateral palmar nerves. Arteriography was done on each digit prior to surgery. Terminally, arteriography was repeated. Sections of bone, nerve, artery, skin, coronary band, and deep flexor tendon were examined histologically. Changes in arterial pattern and bone quality were noted. During the study, 2 of the horses had clinical signs of digital necrosis. The composite findings suggested trauma or infection, or both, of th...
