Electrocardiography (ECG) in horses is a diagnostic tool used to assess the electrical activity of the heart. It involves recording the electrical impulses that govern heartbeats, providing insights into cardiac function and rhythm. This non-invasive method is useful for identifying arrhythmias, conduction disturbances, and other cardiac abnormalities in equine patients. Electrocardiography can be performed at rest or during exercise to evaluate cardiac performance under different physiological conditions. This page compiles peer-reviewed research studies and scholarly articles that explore the methodology, interpretation, and clinical applications of electrocardiography in equine health.
Farlin ME, Jasko DJ, Graham JK, Squires EL.The use of fluorescein-conjugated Pisum sativum agglutinin (FITC-PSA) was evaluated for its ability to distinguish acrosome-intact from acrosome-damaged stallion spermatozoa. Incubation of fresh (acrosome-intact) and frozen-thawed (acrosome-damaged) spermatozoa with FITC-PSA resulted in acrosome-intact spermatozoa that exhibited no fluorescence, while acrosome-damaged spermatozoa exhibited fluorescent staining over the rostral portion of the head and equatorial segment. Experiments using mixtures of various ratios of acrosome-intact and acrosome-damaged spermatozoa determined the precision (in...
Yamamoto K, Yasuda J, Too K.Foetal electrocardiograms (ECG) were obtained from 39 of 50 Thoroughbred foaling mares close to delivery. The 50 newborn foals were studied electrocardiographically during their adaptive period, immediately after birth. In 48 foals there were paroxysmal arrhythmias or mixed arrhythmias. The most common arrhythmias were sinus arrhythmias including wandering pacemaker (32/50) and atrial premature contraction (30/50). The others observed were atrial fibrillation (15/50), ventricular premature contraction (10/50), partial atrioventricular block (7/50), ventricular tachycardia (4/50), atrial tachyc...
Luna SP, Beale NJ, Taylor PM.Atipamezole antagonism of xylazine sedation was evaluated in six ponies. Atipamezole (0.15 mg/kg) or saline was injected intravenously 15 minutes after the ponies had been sedated with xylazine (1.0 mg/kg). Arterial blood pressure and gases, pulse and respiratory rates, the electrocardiogram, nose-to-ground distance and a subjective sedation score were recorded. The pretreatment nose-to-ground distance and PaO2 returned to normal sooner after atipamezole than after saline and the ponies' appetite and normal locomotion also recovered sooner. No significant differences were observed between the ...
Raekallio M.The electrocardiogram of 9 horses was continuously recorded for 24 h with Holter monitoring to examine the variations in heart rate and rhythm during daily routine procedures and at night. Three horses had transient sinus bradycardia, and 3 had periods of sinus tachycardia. Heart blocks were detected in 3 horses, and all horses had periods of sinus arrhythmia. These changes in the heart rate and rhythm were apparently caused by variations in autonomic nervous system tone and they are probably "normal" findings in resting, undisturbed horses. Ventricular premature depolarisations were not obser...
Yamamoto K, Yasuda J, Too K.In 101 newborn Thoroughbred foals and foaling mares, 45 fetal (FECGs) and 101 neonatal electrocardiograms (NECGs) were obtained to investigate neonatal arrhythmias and other parameters including changes in fetal (FHR) and neonatal heart rate (NHR). Moreover, umbilical arterial, venous and jugular venous blood gas tensions and pH immediately after birth were analyzed to compare with the type and the degree of neonatal arrhythmias. Before delivery, in 37 fetuses FHR gradually decreased while in 8 cases it increased after rupture of the chorio-allantois. Abnormal deliveries were related in 5 of t...
Guthrie AJ, Killeen VM, Mülders MS, Grosskopf JF.The ratio of the cardiopulmonary blood volume to stroke volume is called the cardiopulmonary flow index (CPFI). The CPFI can be determined indirectly from the simultaneous recording of a radiocardiogram and an electrocardiogram. The CPFI and cardiac output were measured simultaneously in horses (n = 10) that were diagnosed as having cardiac disease. The diseased subjects were probably all exposed to feed contaminated with the ionophore, salinomycin, and all showed clinical signs indicative of chronic toxic myocarditis. The results obtained from these subjects were compared with those from cont...
Jiang B, Rugh KS, Hatfield DG, Jiang D, Hahn AW.We report on a nonlinear algorithm which identifies R-wave peaks on the surface electrocardiogram, consistent reference points on the left ventricular pressure waveform and the initiation of the QRS complex on the epicardial electrogram. The algorithm has been used to evaluate data from horses, ponies, dogs and humans at rest and during exercise. It permits rapid, accurate evaluation of data on a beat-by-beat basis even with noisy signals and varying waveform configurations. The algorithm facilitates the acquisition of detailed information previously difficult or impossible to obtain by more c...
Jiang B, Rugh KS, Hatfield DG, Jiang D, Hahn AW.We have developed a digital signal analysis technique which can be used to evaluate various cardiac events in ponies and horses at rest and during exercise. The algorithm is designed to identify R-wave peaks on the surface electrocardiogram, consistent reference points on the left ventricular pressure waveform and the initiation of the QRS complex on the epicardial electrogram. We have used the technique to evaluate data from 10 horses and ponies at rest, during strenuous exercise and during experimentally-induced coronary artery occlusion. The technique provided rapid and accurate beat-by-bea...
Muir WW, Reed SM, McGuirk SM.Intravenous administration of quinidine gluconate converted atrial fibrillation (AF) to sinus rhythm in 9 of 12 horses. Twelve horses that were diagnosed by ECG to have AF were administered up to 11 mg of quinidine gluconate/kg of body weight in 1.0- to 1.5-mg/kg bolus injections every 10 to 15 minutes. The total dose of quinidine administered IV ranged from 1.8 to 5.8 g. Increased ventricular rate, apprehension, and mild depression were observed during treatment. Other signs of toxicosis were not observed. One horse was successfully treated with IV administered quinidine gluconate on 3 occasi...
Leblanc PH, Eberhart SW.This study was designed to determine whether the epidural administration of an alpha2 agonist, xylazine, would produce measurable changes in arterial blood pressure, electrocardiographic (ECG) activity and arterial blood gas values in horses. Six horses were given each of four treatments: epidural xylazine, intravenous xylazine, epidural lidocaine and epidural saline. A carotid artery catheter was used to measure arterial blood pressure and to collect samples for blood gas analysis before treatment and at intervals post treatment. Heart rate, arterial pressures, ECG activity and respiratory ra...
Cornick JL, Seahorn TL.During a 3 1/2-year period, cardiac arrhythmias were identified in 6 of 67 horses diagnosed with duodenitis/proximal jejunitis (DPJ). Arrhythmias were detected by auscultation of irregular cardiac rhythm and subsequently were characterized by electrocardiographic evaluation. Arrhythmias included frequent second-degree atrioventricular block, ventricular ectopic depolarizations, and atrioventricular conduction disturbance. In 4 horses, arrhythmias resolved with recovery from the primary problem. One horse died suddenly 66 hours after admission, and another was euthanatized at 72 hours after adm...
Grauerholz H, Jaeschke G.After the onset of training ("breaking") in young standardbred horses within continuing investigations changes of vectors in the QRS-complex were considered. These changes accomplished in two stages. Mainly within the first three months of training the vector R (VR) in limb leads changed to the left and to caudal and dorsal. In a second interval between five and seven months after breaking the vector S (VS) changed to cranial. As main cause the different character of training in both phases is discussed. Additional indicators of age- or development-related causes were not found.
Grauerholz H.Interrelations between respiration and changes in amplitudes of the QRS-complex of the ECG of horses were investigated. The value of the R-vector and both its components Rx and Ry decrease during inspiration and increase in the expiration phase. It means, that the R-waves in leads from cranial to caudal (y, II, aVF) and from right to left (I) become smaller with inspiration and larger with expiration. The difference of the amplitudes may be important, especially in horses with respiratory problems, so that it has to be noted when evaluating electrocardiograms. For that purpose it is not necess...
Escabias MI, Santisteban R, Rubio MD, Tovar P.The correlations between different electrocardiographic variables and plasma concentrations of K, Na and Ca ions were studied in foals of 1 to 14 days of age. The results obtained are only significant in neonate individuals of 1 day of age. Whilst the PQ segment and R wave duration showed a positive linear correlation (p less than or equal to 0.05) with plasma concentrations of Na and Ca ions respectively, the amplitude of the T wave showed a negative linear correlation (p less than or equal to 0.05) with the K ion. Moreover, the variability in duration of the QT and ST intervals can be explai...
Hartley JW, Hahn AW, DeLorey M, Caldwell WM.We have developed and used a system for recording and analyzing the electrocardiogram (ECG) of the horse during exercise. The system consists of a commercial ECG transmitter telemetering a Z lead (base-apex) ECG from an exercising horse. The received data are then remodulated at an audio frequency and stored on a audio cassette recorder. Exercise protocols of up to 10 minutes are digitized using a Macintosh II computer. For rhythm analysis, a computer program to identify the various waves of the ECG uses a modification and refinement of the integrated-squared-derivative (ISD) technique. This t...
Dyson DH, Pascoe PJ.A controlled study of the cardiovascular responses in horses anesthetized with acepromazine (0.05 mg/kg of body weight, IV), guaifenesin (100 mg/kg, IV), thiamylal (5.0 mg/kg, IV), and halothane in O2 (1.2 to 1.4% end-expired concentration) was performed to determine whether hypotension could be prevented by use of various treatments. Six horses were given 5 treatments in a randomized sequence: no treatment (control), methoxamine (0.04 mg/kg, IV), lactated Ringer solution (20.0 ml/kg, IV), 7.5% hypertonic saline solution (4.0 ml/kg, IV), or constant infusion of dobutamine (5.0 mg/kg/min, IV) d...
Tovar P, Escabias MI, Santisteban R.A study of electrocardiograms recorded from foals during the first two weeks of life has been made in order to detect any changes of the cardiac activation and recuperation processes during this period. A stepwise discriminant analysis revealed significant differences between the first and second week of age, fundamentally on the basis of the T and P wave amplitudes which gave the lowest values at 14 days, and on the PQ segment duration that showed the highest values at the same age.
Doonan GR, Brown CM, Mullaney TP, Brooks DB, Ulmanis EG, Slanker MR.Several hundred Michigan horses were accidentally exposed to varying levels of monensin. Severity of effects was proportional to the level of feed contamination; sudden death resulted on at least two premises. Acute signs of cardiovascular impairment occurred on one premises having received feed containing over 200 grams of monensin per tonne. Gross and histological postmortem lesions consisted of acute myocardial necrosis. Although only circumstantially confirmed, investigations led to the suspicion that the source of poisoning was a ration formulation error in a feedmill in southwestern Onta...
Illera JC, Hamlin RL, Illera M.Bipolar and unipolar limb leads and unipolar thoracic lead ECG were obtained from 100 male crossbred horses. P-wave morphologic features were classified according to positivity negativity and monopolarity dipolarity, and the percentage of horses that had P waves of a given morphologic class in each lead was calculated. P-Wave morphologic features of 4 precordial leads were most uniform, with greater than 80% of the horses having a single configuration.
Illera JC, Illera M, Hamlin RL.Electrocardiograms were obtained from 100 male crossbred horses. In addition to standard limb leads, leads were taken from 12 points on the thorax. The QRS complexes were categorized into 1 of 8 forms on the basis of configuration and amplitudes of component deflections. Relative uniformity of QRS was determined for each lead, using the percentage of horses that possess a particular configuration. All unipolar thoracic leads, except those coplanar with the frontal plane, and lead aVR had great uniformity, with greater than 80% of the horses with a QRS of similar contour.
Leduc L, Abraham M, Slack J.Atrial fibrillation (AF) is a rarely reported arrhythmia in otherwise healthy newborn foals, with a single case of cardioversion using procainamide administration described in the literature. Two neonatal Thoroughbred colts were presented to an equine hospital because of an irregularly irregular tachyarrhythmia and poor latching when trying to nurse. History, physical examination, and initial diagnostic testing including ECG and echocardiography confirmed AF without structural heart disease. The 1st foal converted into normal sinus rhythm after treatment with IV metoprolol and quinidine. The 2...
This research investigates the human-horse bond, aiming to unveil the physiological mechanisms regulating interspecies interactions. We hypothesized observing a physiological synchronization in human-horse dynamics, akin to human interactions. Through time-frequency Granger causality analysis of heart rate variability (HRV) and behavioral data, this study reveals the establishment of bidirectional synchronization in HRV between humans and horses. The coupling directionality is influenced by behavior and familiarity. In exploration scenarios led by horses, bidirectional interactions occur, part...
McCrae P, Spong H, Mahnam A, Bashura Y, Pearson W.Several skin preparation techniques are used in electrocardiogram (ECG) monitoring of horses. The objective of this study was to determine which methods produce the greatest signal quality using textile electrodes and standard silver/silver chloride (Ag/AgCl) electrodes. Electrocardiogram data were collected using textile and Ag/AgCl electrodes simultaneously for 4 skin preparation techniques in 6 horses. The effects of skin preparation (cleansing with isopropyl alcohol, with or without shaving the hair) and the effects of the application of a conductive gel were assessed using metrics of sign...
Holmes JR, Rezakhani A.The paper describes changes observed in the T wave and T vectorcardiogram in horse after various periods of exercise. Using radiotelemetry and a bipole lead all horses showed negative T waves immediately after exercise. In some of them this was followed by a markedly positive T deflection. Possible reasons for these changes are briefly discussed.
Steel JD, Hall MC, Stewart GA.Changes that occur in the equine ECG during and after exercise have been described and compared with resting ECG's obtained from the same horses. When the speed of work equals or is greater than "three-quarter pace" (i.e. "even time" or 200 metres in 15 seconds) the high heart rates developed cause the loss of ECG waveforms that are readily discernible at rest. Although differences in the waveforms between horses with normal and abnormal resting ECG's have been observed, the more definitive useful information is the fact that abnormal horses showed significantly higher heart rates than normal ...
Kroneman J.The anatomical and electrophysiological basis of the electrocardiogram are described. Attention is drawn to the fact that the technique of recording has not been standardized and to the failure to file the data obtained on an international scale. Today the ECG is only useful in recording arrhythmias, the clinical significance of which is estimated empirically.
Illera JC, Hamlin RL, Illera M.Bipolar and unipolar limb leads and unipolar thoracic lead ECG were obtained from 100 male crossbred horses. P-wave morphologic features were classified according to positivity negativity and monopolarity dipolarity, and the percentage of horses that had P waves of a given morphologic class in each lead was calculated. P-Wave morphologic features of 4 precordial leads were most uniform, with greater than 80% of the horses having a single configuration.
Tschudi P.The use of the ECG to separate the different phases of the heart cycle registering other physiological signals, to evaluate the fitness and state of training of a horse and to detect a pregnancy of a mare is reported and illustrated in this text.
Hanák J, Jagos P.In 246 horses of the English Thoroughbred breed of several age categories, divided into four test populations, the influence was studied of age and training on the pulse rate and time intervals of ECG (PQ, QRS, QT and QTc). It was found that with the increasing age and training action slowed down gradually. Duration of the atrioventricular path (PQ) is prolonged, time of ventricular activation (QRS) and time of the electrical systole (QT) including its value corrected according to the actual pulse rate (QTC). In this way the origin of the so called sports electrocardiogram in trained race hors...