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Topic:Epidemiology

Epidemiology in horses involves the study of the distribution and determinants of health-related states and events in equine populations. It encompasses the investigation of patterns, causes, and effects of diseases and health conditions within horse populations. This field of study aims to identify risk factors for disease and targets for preventive healthcare. Key components of equine epidemiology include disease surveillance, outbreak investigation, and the study of disease dynamics within herds or regions. Research in this area often focuses on infectious diseases, zoonotic diseases, and the impact of environmental factors on equine health. This page compiles peer-reviewed research studies and scholarly articles that explore various aspects of epidemiology in horses, including disease prevalence, transmission pathways, and strategies for disease prevention and control.
Malassezia species isolated from the intermammary and preputial fossa areas of horses.
Journal of veterinary internal medicine    April 6, 2006   Volume 20, Issue 2 395-398 doi: 10.1892/0891-6640(2006)20[395:msifti]2.0.co;2
White SD, Vandenabeele SI, Drazenovich NL, Foley JE.Malassezia-type yeasts previously have been observed on cytologic examination of the intermammary region of mares that presented with tail-head pruritus; topical antiyeast treatment resolved the pruritus. Further, Malassezia dermatitis has been observed in horses in intertriginous areas such as the udder and prepuce; the species of yeast was not confirmed. It is not known whether healthy mares or male horses can be carriers of this yeast in these body areas. Objective: Malassezia spp. are present in the intermammary region in healthy mares and the preputial fossa in healthy geldings. Methods: ...
Usefulness of a commercial equine IgG test and serum protein concentration as indicators of failure of transfer of passive immunity in hospitalized foals.
Journal of veterinary internal medicine    April 6, 2006   Volume 20, Issue 2 382-387 doi: 10.1892/0891-6640(2006)20[382:uoacei]2.0.co;2
Metzger N, Hinchcliff KW, Hardy J, Schwarzwald CC, Wittum T.Detection of failure of transfer of passive immunity (FTPI) is important in reducing morbidity and mortality in neonatal foals. We investigated the performance of a commercial equine IgG test (SNAP Foal IgG Test Kit) to diagnose FTPI in hospitalized foals. Furthermore, we evaluated the usefulness of serum total protein (STP) and serum globulin (SG) concentrations as indicators of FTPI. Serum IgG concentration was measured by means of the SNAP test and single radial immunodiffusion, and SG and STP concentrations were determined by means of a clinical chemistry analyzer. Subjects were 67 hospita...
Equine viral arteritis.
The Veterinary record    April 4, 2006   Volume 158, Issue 13 455 doi: 10.1136/vr.158.13.455-a
Campbell ML.No abstract available
Management factors affecting stereotypies and body condition score in nonracing horses in Prince Edward Island.
The Canadian veterinary journal = La revue veterinaire canadienne    April 4, 2006   Volume 47, Issue 2 136-143 
Christie JL, Hewson CJ, Riley CB, McNiven MA, Dohoo IR, Bate LA.In North America, there are few representative data about the effects of management practices on equine welfare. In a randomized survey of 312 nonracing horses in Prince Edward Island (response rate 68.4%), owners completed a pretested questionnaire and a veterinarian examined each horse. Regression analyses identified factors affecting 2 welfare markers: body condition score (BCS) and stereotypic behavior. Horses' BCSs were high (mean 5.7, on a 9-point scale) and were associated with sex (males had lower BCSs than females; P < 0.001) and examination date (P = 0.052). Prevalences of crib bi...
The effect of simulated censored data on estimates of heritability of longevity in the Thoroughbred racing industry.
Genetics and molecular research : GMR    March 31, 2006   Volume 5, Issue 1 7-15 
Burns EM, Enns RM, Garrick DJ.We examined the impact of censored data on estimates of heritability of longevity. Longevity, defined as the length of productive racing life of an individual, is influenced by many factors. A simulated data set, modelled on the Irish Thoroughbred industry, was used to estimate heritabilities of longevity. Several scenarios representing various levels of censoring of performance data were created. The heritability of longevity was estimated for each scenario and compared to the estimated heritability of 0.120 for the complete data set. It was found that the estimates of heritability (0.107, 0....
Analysis of equid herpesvirus 1 strain variation reveals a point mutation of the DNA polymerase strongly associated with neuropathogenic versus nonneuropathogenic disease outbreaks.
Journal of virology    March 31, 2006   Volume 80, Issue 8 4047-4060 doi: 10.1128/JVI.80.8.4047-4060.2006
Nugent J, Birch-Machin I, Smith KC, Mumford JA, Swann Z, Newton JR, Bowden RJ, Allen GP, Davis-Poynter N.Equid herpesvirus 1 (EHV-1) can cause a wide spectrum of diseases ranging from inapparent respiratory infection to the induction of abortion and, in extreme cases, neurological disease resulting in paralysis and ultimately death. It has been suggested that distinct strains of EHV-1 that differ in pathogenic capacity circulate in the field. In order to investigate this hypothesis, it was necessary to identify genetic markers that allow subgroups of related strains to be identified. We have determined all of the genetic differences between a neuropathogenic strain (Ab4) and a nonneuropathogenic ...
Survey of equine cutaneous neoplasia in the Pacific Northwest. Valentine BA.A retrospective study examined data regarding equine cutaneous and mucocutaneous neoplasms submitted to the Veterinary Diagnostic Laboratory at Oregon State University in a 3.5-year period. A total of 536 neoplasms were identified, accounting for 30% of the total equine pathology submissions. Sarcoid, squamous cell carcinoma, melanocytic tumors, papillomas, and mast cell tumors were the most common neoplasms, constituting 87.5% of all cutaneous neoplasms. Sarcoids represented 51.4% of all neoplasms and 15.18% of total equine accessions. Sarcoid was most common in paints, quarter horses, and Ar...
Equine disease surveillance, October to December 2005.
The Veterinary record    March 28, 2006   Volume 158, Issue 12 390-392 doi: 10.1136/vr.158.12.390
No abstract available
Mortality of Swedish horses with complete life insurance between 1997 and 2000: variations with sex, age, breed and diagnosis.
The Veterinary record    March 28, 2006   Volume 158, Issue 12 397-406 doi: 10.1136/vr.158.12.397
Egenvall A, Penell JC, Bonnett BN, Olson P, Pringle J.The aim of this study was to evaluate the potential usefulness of the database maintained by the Swedish insurance company Agria for providing mortality statistics on Swedish horses. Mortality statistics (incidence rates and survival) were calculated, both crudely and stratified by sex, age, breed, breed group and diagnosis, for the horses with complete life insurance, which covers most health problems. The total mortality was 415 (95 per cent confidence interval [CI] 399 to 432) deaths per 10,000 horse-years at risk, and the diagnostic mortality, including only deaths with an assigned diagnos...
[Characterization of Rickettsia spp. circulating in a silent peri-urban focus for Brazilian spotted fever in Caratinga, Minas Gerais, Brazil].
Cadernos de saude publica    March 27, 2006   Volume 22, Issue 3 495-501 doi: 10.1590/s0102-311x2006000300004
Cardoso LD, Freitas RN, Mafra CL, Neves CV, Figueira FC, Labruna MB, Gennari SM, Walker DH, Galvão MA.The present study was intended to characterize Rickettsia spp. circulating in arthropod vectors in Caratinga, Minas Gerais, Brazil, by PCR and to investigate the presence of antibodies against the spotted fever Rickettsiae group (SFRG) in dogs and horses. 2,610 arthropods were collected and taxonomically identified. DNA samples obtained from these vectors were submitted to PCR and cycle-sequenced. Ctenocephalides and Amblyomma cajennense showed sequences presenting 100.0% homology with R. felis. A sequence obtained from Rhipicephalus sanguineus showed 99.0% homology with R. felis, and a sequen...
West Nile virus activity in Latin America and the Caribbean.
Revista panamericana de salud publica = Pan American journal of public health    March 23, 2006   Volume 19, Issue 2 112-117 doi: 10.1590/s1020-49892006000200006
Komar N, Clark GG.West Nile virus (Flavivirus: Flaviviridae; WNV) has spread rapidly throughout the Caribbean Basin since its initial detection there in 2001. This report summarizes our current knowledge of WNV transmission in tropical America. Methods: We reviewed the published literature and consulted with key public health officials to obtain unpublished data. Results: West Nile virus infections first appeared in human residents of the Cayman Islands and the Florida Keys in 2001, and in apparently healthy Jamaican birds sampled early in 2002. Serologic evidence of WNV infection in 2002 was detected in horses...
A comparison of survival models for assessing risk of racehorse fatality.
Preventive veterinary medicine    March 20, 2006   Volume 74, Issue 1 3-20 doi: 10.1016/j.prevetmed.2006.01.003
Henley WE, Rogers K, Harkins L, Wood JL.Survival analysis was used to assess risk factors for fatal injuries on UK race courses. This allowed assessment of variation due to temporal horse-level effects, including previous racing intensity and historical distribution of race types, as well as race-level factors. Comparisons were made between measuring survival time as number of days and as number of races to injury from the first race. Two related models were presented for time as number of races to injury: a Cox regression model fitted using partial likelihood, with the Efron approximation to handling ties, and a discrete-time logit...
Report of the equine herpesvirus-1 Havermeyer Workshop, San Gimignano, Tuscany, June 2004.
Veterinary immunology and immunopathology    March 20, 2006   Volume 111, Issue 1-2 3-13 doi: 10.1016/j.vetimm.2006.01.004
Slater JD, Lunn DP, Horohov DW, Antczak DF, Babiuk L, Breathnach C, Chang YW, Davis-Poynter N, Edington N, Ellis S, Foote C, Goehring L, Kohn CW....Amongst the infectious diseases that threaten equine health, herpesviral infections remain a world wide cause of serious morbidity and mortality. Equine herpesvirus-1 infection is the most important pathogen, causing an array of disorders including epidemic respiratory disease abortion, neonatal foal death, myeloencephalopathy and chorioretinopathy. Despite intense scientific investigation, extensive use of vaccination, and established codes of practice for control of disease outbreaks, infection and disease remain common. While equine herpesvirus-1 infection remains a daunting challenge for i...
Questions reliability of fecal egg counts in equine study.
Journal of the American Veterinary Medical Association    March 17, 2006   Volume 228, Issue 5 688-689 
Bradley RE.No abstract available
Epidemiology of equine performance wastage: importance of analysing facts and implementing their message in management.
Equine veterinary journal    March 16, 2006   Volume 38, Issue 2 98-100 doi: 10.2746/042516406776563279
Parkin TD, Rossdale PD.No abstract available
The risk of a horse-and-rider partnership falling on the cross-country phase of eventing competitions.
Equine veterinary journal    March 16, 2006   Volume 38, Issue 2 158-163 doi: 10.2746/042516406776563314
Murray JK, Singer ER, Morgan KL, Proudman CJ, French NP.Fatalities resulting from horse falls occurring during the cross-country phase of eventing competitions initiated epidemiological investigation of the risk factors associated with horse falls. Objective: To identify variables that increased or decreased the risk of a horse fall during the cross-country phase of an eventing competition. Methods: Data were collected from randomly selected British Eventing competitions held in Great Britain during 2001 and 2002. Data were obtained for 173 cases (jumping efforts resulting in a fall of the horse-and-rider partnership) and 503 matched controls (jump...
Larval cyathostominosis in horses in Ontario: an emerging disease?
The Canadian veterinary journal = La revue veterinaire canadienne    March 16, 2006   Volume 47, Issue 1 80-82 
Peregrine AS, McEwen B, Bienzle D, Koch TG, Weese JS.From 1991 to 2003, 24 cases of larval cyathostominosis were diagnosed at postmortem in equids, 15 (63%) from 2001 to 2003. Cases occurred from September to May, the majority from October to December. Median age was 12 mo. Diarrhea, colic, and weight loss were common clinical signs. Hypoalbuminemia and microcytosis were consistent findings. Cyathostominose larvaire chez des chevaux en Ontario: une maladie émergente? De 1991 à 2003, 24 cas de cyathostominose larvaire ont été diagnostiqués à l’examen post mortem chez des équidés dont 15 (63 %) entre 2001 et 2003. Les cas étaient rappor...
Clostridium difficile associated diarrhoea in horses within the community: predictors, clinical presentation and outcome.
Equine veterinary journal    March 16, 2006   Volume 38, Issue 2 185-188 doi: 10.2746/042516406776563369
Weese JS, Toxopeus L, Arroyo L.No abstract available
Factors associated with failure of thoroughbred horses to train and race.
Equine veterinary journal    March 16, 2006   Volume 38, Issue 2 113-118 doi: 10.2746/042516406776563305
Wilsher S, Allen WR, Wood JL.The low productivity associated with training and racing of young Thoroughbreds (TBs) in the UK due to athletic inability, injury and disease requires further study. Objective: To identify the time points and causes of losses during growth and training phases of a cohort of 1022 TB foals born in 1999 up to the end of their third year. Methods: Movement and fate of 1022 Thoroughbred foals conceived in 1998 and born live in 1999 were monitored from birth to age 3 years. Those (n = 562) that entered training age 2 and/or 3 years with one of 161 registered trainers in Britain or Ireland in 2001/2 ...
Clinical findings, diagnosis, prevalence and predisposing factors for lameness localised to the middle carpal joint in young Standardbred racehorses.
Equine veterinary journal    March 16, 2006   Volume 38, Issue 2 152-157 doi: 10.2746/042516406776563332
Steel CM, Hopper BJ, Richardson JL, Alexander GR, Robertson ID.Lameness related to the middle carpal joint (MCJ) occurs in up to 30% of young Standardbred horses in race training and the incidence increase with radiographic severity of third carpal bone (C3) sclerosis on DPr-DDIO (skyline) view of the carpus. Factors predisposing horses to carpal injury have not been well investigated. Objective: To determine the importance of MCJ lameness as a cause of wastage in young Standardbred racehorses, stage of training at which it occurs and predisposing factors, and to describe clinical findings and diagnosis. Methods: Standardbred horses (n = 114) entering the...
Investigation of equine influenza cases exhibiting neurological disease: coincidence or association?
Journal of comparative pathology    March 9, 2006   Volume 134, Issue 2-3 231-235 doi: 10.1016/j.jcpa.2005.09.001
Daly JM, Whitwell KE, Miller J, Dowd G, Cardwell JM, Smith KC.Equine influenza is usually a transient and self-limiting disease. However, during an outbreak of equine influenza in the UK in 2003 there were reports of unusually severe clinical signs among unvaccinated animals. Two influenza-infected horses developed neurological signs, and one was subjected to euthanasia. Post-mortem examination of the brain revealed viral-type non-suppurative encephalitis, and influenza virus antigen was demonstrated by immunolabelling of sections of nasal mucosa. A syndrome known as influenza-associated encephalopathy has been described in man. Although not proved, the ...
Survey on the subject of equine Lyme borreliosis.
International journal of medical microbiology : IJMM    March 9, 2006   Volume 296 Suppl 40 274-279 doi: 10.1016/j.ijmm.2006.01.004
Gall Y, Pfister K.According to the results of a questionnaire on equine Lyme borreliosis addressing veterinarians in Germany, the existence of the disease was confirmed by more than half of the 118 participants. Practitioners who regarded Borrelia burgdorferi as a pathogen of horses seemed to be more sensitized in terms of the number of annually diagnosed cases as well as the frequency of occurrence of tick infestation with equine patients or prophylactic treatments against ectoparasites by horse owners. Chronically poor performance and diverse orthopaedic problems were the clinical symptoms most often leading ...
The Fell pony immunodeficiency syndrome also occurs in the Netherlands: a review and six cases.
Tijdschrift voor diergeneeskunde    March 7, 2006   Volume 131, Issue 4 114-118 
Butler CM, Westermann CM, Koeman JP, Sloet van Oldruitenborgh-Oosterbaan MM.Over the last ten years a fatal syndrome associated with immunodeficiency and severe anaemia has been reported in young Fell pony foals in the UK. Affected foals are usually normal at birth but from the age of 2-4 weeks they progressively lose condition and become severely anaemic. Signs of immunodeficiency become apparent at around 3-4 weeks of age. Morbidity is low but mortality is 100% despite intensive treatment. Affected foals die or are euthanized usually before they reach the age of 3 months. A single autosomal recessive gene is suggested to be on the basis of the syndrome. Recently, af...
Seroprevalences of Toxoplasma gondii and Neospora sp. infections in Swedish horses.
Veterinary parasitology    March 3, 2006   Volume 138, Issue 3-4 194-199 doi: 10.1016/j.vetpar.2006.02.002
Jakubek EB, Lundén A, Uggla A.Sera from 414 Swedish horses were investigated for the presence of antibodies to Toxoplasma gondii and Neospora sp. by the T. gondii direct agglutination test (DAT), and an Neospora caninum iscom-ELISA. Five sera (1%) had a titre >1:40 in DAT, but when analysed by immunoblotting against T. gondii antigens only two of them were positive, giving a seroprevalence of 0.5%. Since the Neospora iscom ELISA had not been validated for equine sera it was used for an initial screening, and all sera with an optical density exceeding 0.200 absorbance units were selected for further investigation by immu...
[MRSA–not just a problem in hospitals].
Medizinische Monatsschrift fur Pharmazeuten    March 2, 2006   Volume 29, Issue 2 45 
Heinzl S.No abstract available
Changes in heart rate and heart rate variability in Thoroughbreds during prolonged road transportation.
American journal of veterinary research    March 2, 2006   Volume 67, Issue 3 455-462 doi: 10.2460/ajvr.67.3.455
Ohmura H, Hiraga A, Aida H, Kuwahara M, Tsubone H, Jones JH.To determine whether evaluation of heart rate (HR) and HR variability (HRV) during prolonged road transportation in horses provides a sensitive index of autonomic stimulation. Methods: Five 2-year-old Thoroughbreds. Methods: ECGs were recorded as horses were transported for 21 hours in a 9-horse van. Heart rate, high-frequency (HF) power, low-frequency (LF) power, and LF-to-HF ratio from Fourier spectral analyses of ECGs were calculated and compared with values recorded during a 24-hour period of stall rest preceding transportation. Results: HR, HF power, and LF power had diurnal rhythms durin...
Vaccination against equine influenza: quid novi?
Vaccine    February 28, 2006   Volume 24, Issue 19 4047-4061 doi: 10.1016/j.vaccine.2006.02.030
Paillot R, Hannant D, Kydd JH, Daly JM.Equine influenza virus is a leading cause of respiratory disease in the horse. Equine influenza vaccines containing inactivated virus were first developed in the 1960s. Despite their intensive use, equine influenza outbreaks still continue to occur and therefore new strategies of vaccination are necessary to improve vaccine efficacy. Numerous methods of vaccination have been evaluated and commercialised in the horse, the most recent being the cold-adapted influenza virus and poxvirus-based vaccines. As a large animal model, the horse is also a useful species in which to evaluate the potential ...
EHV-1 and EHV-4 infection in vaccinated mares and their foals.
Veterinary immunology and immunopathology    February 28, 2006   Volume 111, Issue 1-2 41-46 doi: 10.1016/j.vetimm.2006.01.007
Foote CE, Love DN, Gilkerson JR, Wellington JE, Whalley JM.A silent cycle of equine herpesvirus 1 infection was described following epidemiological studies of unvaccinated mares and foals on a Hunter Valley stud farm. Following the introduction of routine vaccination with an inactivated whole virus equine herpesvirus 1 (EHV-1) and equine herpesvirus 4 (EHV-4) vaccine in 1997, a subsequent study identified excretion of EHV-1 and EHV-4 in nasal swab samples tested by PCR from vaccinated mares and their unweaned, unvaccinated foals. The current sero-epidemiological investigation of vaccinated mares and their young foals found serological evidence of EHV-...
Babesia–a historical overview.
Veterinary parasitology    February 28, 2006   Volume 138, Issue 1-2 3-10 doi: 10.1016/j.vetpar.2006.01.035
Uilenberg G.The history of the genus Babesia is briefly outlined. The classical differences with the main other genus of non-pigment-forming hemoparasites, Theileria, are the absence of extra-erythrocytic multiplication (schizogony) in Babesia and the cycle in the vector tick, which includes transovarial transmission in Babesia but only transstadial transmission in Theileria. Also, the multiplication in the red cell of Babesia, by budding, most often results in two daughter cells (merozoites), while that of Theileria gives four merozoites, often as a Maltese cross. In particular this means that what is st...
Heterogeneity of Borrelia burgdorferi sensu lato and their reflection on immune response.
Annals of agricultural and environmental medicine : AAEM    February 25, 2006   Volume 12, Issue 2 211-216 
Stefancíková A, Derdáková M, Stepánová G, Pet'ko B, Szestáková E, Skardová I, Cisláková L.Geographically different strains of Borrelia burgdorferi sensu lato (B. burgdorferi sensu stricto Ir 105, B. burgdorferi s.s. + B. afzelii V 123, B. garinii Ir 112 - isolates from eastern Slovakia, B. garinii K24 - isolate from western Slovakia and B. burgdorferi s.s. B 31 - American strain) were compared as antigens for serological study of Lyme borreliosis by IgG ELISA on a group of horses from eastern Slovakia. In a set of 101 horse serum samples, positivity with the use of Ir 105 strain was 53 (52.4%), with V 123 51 (51.49%), with Ir 112 48 (47.5%), with K 24 47 (46.5%) and with B 31 only ...