Omneity® Pellets
All-In-One Vitamin & Mineral Pellet
Topic:Equine Health
Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
[Interaction of bis-phosphorylated methanes with mammalian esterases]. The interaction of human erythrocyte acetylcholinesterase, horse serum butyrylcholinesterase and rat liver carboxylesterase with insecticides (RO)2P(O)SCH(COOEt)SP(O)(OR)2 (I) and (RO)2P(O)SCH(COOEt)OP(S)(OR)2 (II) was studied. The type I and II compounds were not hydrolyzed by carboxylesterase and inhibited the esterases irreversibly. A complex pattern of inhibition of acetylcholinesterase and butyrylcholinesterase by these compounds was caused by kinetically-manifested formation of an enzyme-inhibitor complex. The compounds I and II were more selective towards butyrylcholinesterase than towa...
Extenders for preservation of canine and equine spermatozoa at 5 degrees C. Two experiments were conducted to evaluate the effects of six extenders and three glycerol levels on the motility of sperm stored at 5 degrees C. Using a split-ejaculated design, semen from 10 dogs and 12 stallions was extended with egg-yolk-tris (EYT), egg-yolk-bicarbonate (EGB), Beltsville F-3 (BF-3), Cornell University (CUE), caprogen (CAP) and heated skim milk (SM) extenders. After cooling to 5 degrees C, additional extender containing 0% to 12% glycerol was added to provide a final concentration of 0%, 3% or 6% glycerol. Regardless of glycerol level, a higher (P<0.05) percentage of can...
Skeletal disease in a hypothyroid foal. Hypothyroidism was diagnosed in a 5-month-old Thorough-bred colt by clinical and clinico-pathology examinations, thyroid stimulating hormone response test and by microscopic evaluation of the thyroid gland. Skeletal lesions included delayed appearance of ossification centers and delayed development of bone in cartilage models, delayed closure of epiphyseal plates, transverse trabeculation in metaphyses, osteochondrosis dissecans and subchondral cysts.
Effectiveness of ivermectin paste for removal of nematodes in the horse. Thirteen Standardbred horses, two to five years of age, were treated with ivermectin paste per os at 200 mug/kg of body weight and 13 were untreated. Two weeks after treatment, previously untreated horses were given the paste. Fecal samples were collected from all horses at the time of treatment and periodically thereafter up to 14 weeks and were examined for nematode eggs using the Cornell-McMaster dilution and the Cornell-Wisconsin double centrifugation procedures.All horses consumed the paste readily and had no signs of toxicosis. Strongyle eggs were found in the feces of all horses before ...
Characterization of intrauterine mobility of the early equine conceptus. Intrauterine mobility patterns of the embryonic vesicle were characterized on Days 9 to 17 after ovulation in pony mares using real-time ultrasonography (n=5 or 7 mares per day). The location of the vesicle was determined by dividing the uterus into right horn, left horn, and body. Each uterine horn was further divided into three approximately equal portions (cranial third, middle third, caudal third), yielding seven segments (body plus three portions of each horn). Location of the vesicle within the uterus was recorded every five minutes for two consecutive hours (25 location determinations p...
Protozoal myeloencephalitis in horses in California. Three cases of equine protozoal myeloencephalitis were diagnosed over a 12-month period in horses that had never left the state of California. These cases suggest that the disease is enzootic in California.
Streptococcus durans: an unexpected enteropathogen of foals. Streptococcus durans was isolated from a foal with profuse watery diarrhea and caused a similar syndrome when inoculated into foals via the orogastric route. The most consistent and striking histological feature was the extensive colonization of the mucosal surface of the small intestine by S. durans. Associated mucosal changes were mild to modeate, and brush border lactase and alkaline phosphatase production were depressed. S. durans also induced acute diarrhea in young gnotobiotic piglets. Mucosal changes were mild and, as with foals, the mucosal surface of the small intestine was colonized ...
Usefulness of lymphocyte typing to exclude incorrectly assigned paternity in horses. Lymphocyte typing can be used to detect incorrectly identified parentage of horses. Efficacies of lymphocyte typing to solve paternity questions were calculated using gene frequency estimates of equine lymphocyte antigen (ELA) markers for Thoroughbreds and Standardbreds. Probabilities that ELA typing will detect an incorrectly assigned sire were 68.7% in Thoroughbreds, 67.9% in pacing Standardbreds, and 62.0% in trotting Standardbreds. These calculations demonstrate that ELA typing is among the most efficacious genetic systems for solving paternity questions in horses. Likewise, it could also ...
Electron microscopy of equine respiratory viruses in organ cultures of equine fetal respiratory tract epithelium. Organ cultures of equine fetal tracheal and nasal turbinate epithelium were inoculated with equine influenza virus-A1 (EIV-A1), equine herpesvirus-1 (EHV-1), or equine rhinovirus-1 (ERV-1). Infected organ cultures were processed for scanning and transmission electron microscopy at various intervals and were compared with noninfected controls. Organ cultures inoculated with ERV-1 appeared normal with the exception of rare island-like lesions in infected nasal turbinate. Virus particles were not seen in thin sections of organ cultures infected with ERV-1. The EHV-1 caused extensive loss of the e...
Techniques and applications of transabdominal ultrasonography in the pregnant mare. To establish the feasibility of utilizing high-frequency ultrasound to image equine fetal development transabdominally, in vitro and in vivo observations were made. Three fetuses retrieved from mares that died from various causes were scanned in vitro to establish fetal images from various orientations. A total of 50 mares ranging in age from 4 to 16 years and representing various breeds were scanned intermittently from 100 days of gestation to parturition. Fetal parts, amniotic fluid, placental membranes, and motion patterns could be reliably identified. Fetal heart rates decreased from 180 b...
Antibodies to Berne virus in horses and other animals. After inoculation into 2 foals, Berne virus induced neutralizing antibody, but did not cause clinical symptoms. In a horizontal study of seropositive mares and their offspring, a decline of maternal antibodies and a sudden synchronous seroconversion in all foals were observed, again without clinical symptoms. The virus is widespread in the Swiss horse population and has been so during the last decade; rises in antibody titers were noted in 9% of paired sera sampled at random. Positive reactions were also obtained in serum neutralization tests and ELISA using small numbers of horse sera from Ge...
Inspiratory airway CO2 loading in the pony. To determine if CO2-sensitive airway receptors are important in the control of breathing, CO2 was preferentially loaded into the respiratory airways in conscious ponies. The technique involved adding small amounts of 100% CO2 to either the latter one-third or latter two-thirds of the inspiratory air in an attempt to raise CO2 concentrations in the airway dead space independent of the arterial blood. Arterial blood gas tensions (PCO2 and PO2) and pH, as well as respiratory output (minute volume, tidal volume, and respiratory rate), were measured in a series of 20 experiments on 5 awake ponies. ...
Equine plasma banking: collection by exsanguination. A procedure was developed for the collection, preparation, storage, and administration of equine plasma. The technique involved exsanguination of anesthetized donor horses via carotid artery catheterization with a large-bore cannula. Blood was collected into plastic bags, allowed to settle by gravity, then transferred into storage bags and frozen. These were quickly thawed when needed.
Pathogenicity of equine herpesvirus 1 subtype 2 for foals and adult pony mares. Three pony mares and 4 pony foals were inoculated with a subtype 2 strain of equine herpesvirus 1. Foals had periods of fever 12 h and 2.5 days after inoculation and leukopenia, involving both neutrophils and lymphocytes, followed by leukocytosis. Mares had transient fever and leukopenia 24 hours after inoculation that were less severe than in foals. An increase in circulating virus-neutralizing antibody was seen in 2 of 3 inoculated mares, but not in foals. Attempts to isolate virus from blood were unsuccessful. These studies show that equine herpesvirus 1 subtype 2 is a mild pathogen for pon...
A survey of adverse effects associated with ivermectin use in Louisiana horses. In a survey of 13 Louisiana equine practices, it was determined that 366 of 3,316 horses developed adverse reactions following use of ivermectin, with 3 of the horses having more than 1 reaction. Almost all of the reactions were of minor to moderate concern; however, 1 death was reported. Three hundred and thirty-two (91% of all reactions) were reported as ventral midline pruritus or edema (10% of all doses). Fifteen (0.45%) were transient injection site swelling and/or stiffness. Eleven horses (0.33%) developed limb edema. Eyelid edema was reported in 4 horses (0.12%). Two horses (0.06%) had ...
The effect of racetrack design on gait symmetry of the pacer. A survey of a western Canadian racetrack determined the superelevation and transition curves to be less than the cited design standards. High-speed cinematography was used to film seven Standardbred pacers as they proceeded around one curve of the track at racing speed and for each horse 19 temporal stride parameters were obtained from these films using a film analyzer system. Average velocities were calculated and the mean stride length was found to vary from 5.08 m to 5.77 m. In all frames analyzed the hind foot was observed to contact the track surface prior to the ipsilateral forefoot and ...
Isolation and partial characterization of bovine and equine factor D. Bovine and equine factor D were purified to apparent homogeneity as evidenced by a single protein staining band on 7.5-17.5% SDS-PAGE slab gels under both reducing and non-reducing conditions. An apparent mol. wt of 15,000 for bovine D and 22,500 for equine D were noted after SDS-PAGE gel analysis of both reduced and non-reduced preparations. A single polypeptide chain for both proteins was evidenced by the lack of any change in the electrophoretic mobility under each of these conditions. The bovine and equine D were enriched 3347- and 9447-fold, with a 20 and 29% yield of hemolytic activity, ...
Attachment of E. coli-bearing K88 antigen to equine brush-border membranes. Equine small intestinal brush-border membranes, from 40 adult horses were tested in vitro for the presence of receptors for the Escherichia coli adhesive antigens K88ab, K88ac and K99. Only K88-positive strains of E. coli adhered strongly to horse brush-border membranes. In contrast, a K88-negative mutant strain J2, 2 K99-positive strains and 3 E. coli strains isolated from foals failed to adhere to horse brush-border membranes. Purified K88ac pili when reacted with equine brush-border membranes inhibited to a great extent the adhesion of K88-positive E. coli. Similarly, K88-positive E. coli p...
Femoral fracture repair complicated by vascular injury in a foal. A comminuted, mid-diaphyseal femoral fracture was diagnosed radiographically in a 4-month-old Quarter Horse colt. Disruption of the distal blood supply was suspected, as evidenced by coolness and diminished pulses of the distal portion of the limb. The fracture was repaired by compression plating but the foal's condition continued to deteriorate. A femoral arteriogram of the affected limb was obtained. Positive contrast agent was visible only as far as the mid-shaft of the femur. The foal was euthanatized and the postmortem examination revealed a transected popliteal artery accounting for isch...
Serum testosterone levels in young normal horses. Serum testosterone levels were measured in normal young male horses (29 to 34 weeks old). No differences were found between gelded and intact males. The values for all the horses were low. On the basis of their testosterone levels, all the horses were prepubertal.
Functional and ultrastructural changes in neutrophils from mares and foals experimentally inoculated with a respiratory tract strain of equine herpesvirus-1. Neutrophils isolated from venous blood of adult and foal ponies inoculated with equine herpesvirus-1 were evaluated by in vitro function tests and by electron microscopy. Foals had fever and severe neutropenia 24 hours after inoculation; increased neutrophil random migration under agarose and decreased antibody-dependent cell-mediated cytotoxicity were significant at 24 hours, but values had returned to preinoculation levels by 72 hours. Mares had fever and leukopenia of less severity, increases in neutrophil migration, and longer persistence of primary granule release than were seen in foals....
Evaluation of ivermectin against later fourth-stage Strongylus vulgaris in ponies at two and five weeks after treatment. The efficacy of ivermectin against later fourth-stage Strongylus vulgaris larvae was studied in pony foals at 14 and 35 days after treatment. These foals had been reared parasite-free, inoculated with 500 infective larvae and 56 days later given either ivermectin at 200 micrograms/kg or a placebo intramuscularly. At necropsy, foals were examined for lesions and larvae grossly and histologically. Ivermectin was found to be highly effective (98.6%) against later fourth-stage larvae in five foals which were examined at 35 days after treatment, but not in five others examined at 14 days (72.5%). I...
