Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
McGuire TC, Poppie MJ, Banks KL.Thirty sick Arabian foals and 78 clinically normal Arabian foals were examined for combined (B- and T-lymphocyte) immunodeficiency. Diagnosis was based on lymphocyte counts and serum immunoglobulin (Ig) content or microscopic examination of lymphoid organs. Ten of the 30 sick foals and 2 of the 78 clinically normal foals had combined immunodeficiency. The 2 affected foals in the group of 78 subsequently developed fatal pneumonia.
Lymphocyte counts were made from 9 of the 12 immunodeficient foals; the range was 0 to 936/cmm., whereas the normal mean was 4,119/cmm., with a standard deviation ...
Allen WR, Stewart F, Cooper MJ, Crowhurst RC, Simpson DJ, McEnery RJ, Greenwood RE, Rossdale PD, Ricketts SW.This research investigates the use of synthetic prostaglandin analogues, specifically ICI-81008 and ICI-79939, in mares for inducing luteolysis, the regression of the corpus luteum, to manage infertility issues. The study […]
Lindholm A, Piehl K.LINDHOLM, ARNE and KARIN PIEHL: Acta vet. scand. 1974, , 287–309. — Measurements of metabolites, electrolytes, water, RNA and protein concentrations, the activity of certain muscle enzymes (SDH and PFK) and muscle fibre composition were made on biopsy specimens from the gluteus medius muscle of 68 standardbred horses, ½ to 8 years old. The muscle fibres were classified in 3 major categories, slow twitch (ST), fast twitch and high oxidative (FTH) and fast twitch (FT) fibres. The percentage of FTH fibres was higher after the age of 4 years, averaging 54 %. ST fibres comprised 24 % and this...
Pulley LT, Shively JN.Tyzzer's disease was diagnosed in a 17-day-old foa l after the demonstra tion
of mu ltip le foci of hepat ic necro sis and organisms morphologically compatible with
Bacillus piliformis in hepa tocytes at the margins of the necrotic foci. Th e bac illi were
300 to 500 nm in diameter with occa sional giant bacilli 1000 nm in d iameter. Ma ny intranuclear organisms were seen, and a n a pparent sequence of nuclear penetration by these
organisms was demonstrated . There was hem orrhage in the hear t a nd inflamma tory
cha nges in the mesenteric lymph node . Enteritis was no t pre sent in the j...
Pauli BU, Rossi Straub R.A trabecular adenoma of the pars intermedia of the hypophysis was seen in a 13-year-old half-bred mare that presented symptoms corresponding to Cushing's disease of man. The spindle-shaped tumor cells were for the most part ‘light’, seldom ‘dark’. Both of them were characterized by well-developed rough endoplasmic reticulum, small Golgi apparatus, and typical secretory granules with a diameter of about 200 μm. The pituitary tumor and the symptoms were accompanied by increased plasma adenocorticotrophic hormone (ACTH) and by bilateral hyperplasia of the adrenal cortex. The tumor cells ...
Carter EI, Valli VE, McSherry BJ.The peripheral blood cells from Standard bred horses were subjected to procedures which will separate equine peripheral blood cells with good precision and efficiency into red cell, leukocyte, and platelet fractions. The separated cells have normal morphology and the differential count of the separated granulocytes and lymphocytes is unchanged from that of the original sample.
Phillips AW, Courtenay JS, Ruston RD, Moore J, Baker C, Epps HB.A simple apparatus is described for the collection of plasma from horses while maintaining their blood in extracorporeal circulation. Using this device, nearly 2.5 kg of plasma protein was collected from a horse during a period of 3 weeks without any obvious adverse effect upon the animal. The blood’s packed cell volume showed little variation throughout this period, although its content of plasma protein was found to fall. The normal plasma protein level was almost completely re-established after 3 weeks rest. A horse immunized with tetanus toxoid and subjectcd to repeated cycles of plasmap...
Ek N.Levels of the immunoglobulins IgG and IgG(T) in serum in Norwegian horses of the breeds “Døle” and “Fjord” were determined by the quantitative radial immunodiffusion test. No significant differences were apparent between the 2 Norwegian breeds. The immunoglobulin levels were approximately in the same range as previously reported for Shetland ponies. Immunoglobulins could not be detected in the newborn foal. As early as 24 hrs. after birth the mean immunoglobulin level was within the adult range. After a drop during the first month of life, the immunoglobulins increased. IgG(T) rose mo...
Neuvonen E, Estola T.A serological survey on the occurrence of group-specific chlamydial antibodies in random sera of Finnish sheep, cattle and horses was performed. The whole material consisted of 1347 serum samples, including 432 ovine, 454 bovine and 461 equine sera. The sera were sent to the laboratory for various serological tests during 1968–1972. Of the ovine sera 9.5%, bovine 12.8 % and equine 7.1 % showed a titer ≥ 1:16 in the complement fixation test. No definite geographic differences could be found in the distribution of the herds which showed positive results. The ubiquity of chlamydial infections...
Smith ID.Progesterone concentration was measured by a protein-binding assay in peripheral plasma samples taken from 8 thoroughbred mares throughout pregnancy and for 2 days after parturition. There were considerable differences between individuals at any one time in gestation but, on average, levels rose during the first 60 days of gestation, fell to a minimum at about 180 days when the accessory corpora lutea regress and finally reached their highest mean value of 11.5 mg/ml±1.2 (S.E.M.) during the period 270 days to term, significantly higher than the mean, 7.6 ng/ml±0.5 (S.E.M) for the whole of ge...
Walker NL, Patout AR, Cater M.Hereditary equine regional derma asthenia (HERDA), an autosomal-recessive trait, found in Quarter Horses, causes abnormal collagen structure. Owing to current breeding practices, 3.5% of registered quarter horses and 28.3% of the cow horse population are heterozygote carriers. Research demonstrated homozygote horses develop hyperextensible skin susceptible to injury and other abnormal tissues containing high fibrillar collagen content. No research exists determining the effects of the disease in heterozygote carriers. Currently, 30% of cutting sires are HERDA carriers, potentially increasing t...
Yamarik TA, Wilson WD, Wiebe VJ, Pusterla N, Edman J, Papich MG.Using a randomized, cross-over study design, ciprofloxacin was administered i.g. to eight adult mares at a dose of 20 mg/kg, and to seven of the eight horses at a dose of 5 mg/kg by bolus i.v. injection. The mean C(0) was 20.5 μg/mL (±8.8) immediately after i.v. administration. The C(max) was 0.6 μg/mL (±0.36) at T(max) 1.46 (±0.66) h after the administration of oral ciprofloxacin. The mean elimination half-life after i.v. administration was 5.8 (±1.6) h, and after oral administration the terminal half-life was 3.6 (±1.7) h. The overall mean systemic availability of ...
Partlow JL, Lustgarten M, Redding WR.To the authors' knowledge, the ultrasonographic appearance of hair shafts within a synovial structure of the horse has not been described previously. The purpose of this descriptive study was to illustrate the clinical, ultrasonographic, and arthroscopic characteristics of confirmed hair shafts within synovial structures of seven horses. A review of medical records of the Farm and Equine Veterinary Medical Center at North Carolina State University College of Veterinary Medicine identified seven horses with clinical signs suspicious for inflammatory or septic synovitis/tenosynovitis that had ha...
Malton R, Nagy A.Diffusion of local anaesthetic solution after a mid-pastern ring block has not been investigated. Objective: To demonstrate potential distribution of local anaesthetic solution following injection of radiodense contrast medium as performed for a mid-pastern ring block. Methods: Experimental. Methods: Twelve mature horses were used. One and a half ml radiodense contrast medium was injected over the medial or lateral palmar digital nerve at the level of the proximal aspect of the ungular cartilages. A dorsal ring block was performed on the ipsilateral side, 1.5 cm proximal to the palpable palm...
Clabough DL, Duckett W.An 8-year-old Arabian gelding with septic cholangitis and peritonitis was successfully treated with trimethoprim/sulfadiazine. The gelding was referred for evaluation of signs of abdominal pain, icterus, fever, and weight loss. Peritoneal fluid analysis revealed septic and suppurative peritonitis. Culture of the peritoneal fluid yielded Escherichia coli and Klebsiella pneumoniae, which were sensitive to trimethoprim/sulfadiazine. On the basis of results of hepatic ultrasonography, a diagnosis of septic cholangitis also was made. The horse was treated with 30 mg of trimethoprim/sulfadiazine/kg,...
Geiser DR, Andrews FM, Rohrbach BW, White SL, Maykuth PL, Green EM, Provenza MK.Blood ionized calcium (Ca2+) and pH; plasma lactate concentrations; and total protein, total calcium (CaT), albumin, and phosphorus concentrations in serum were determined in 40 healthy horses before (T1), at the finish line (T2), and 10 minutes after the finish (T3) of the cross-country phase of a 3-day-event competition. Mean (+/- SEM) Ca2+ concentrations decreased from 6.22 +/- 0.04 mg/dl at T1 to 5.04 +/- 0.07 mg/dl at T2 (P < or = 0.05). This decrease was accompanied by a nonsignificant increase in CaT between T1 and T2. The mean (+/- SEM) percent ionization of calcium decreased significa...
Dik KJ, Németh F, Merkens HW.The radiological and clinical interpretation of alterations of the navicular bone, the interaction of radiological and clinical symptoms in relation to the age of the animal, the influence of work-load on this interaction and the possibility of predicting navicular disease at an early stage are discussed. The discussion is based on experience in a study of 130 horses.
Martinez-Lopez J, Brown JA, Werre SR.To compare the prevalence of incisional complications after skin closure with n-butyl cyanoacrylate (NBC) or stainless-steel skin staples (SS) after ventral midline celiotomy for colic surgery in the horse. Methods: Retrospective study (2014-2018). Methods: Two hundred eighteen horses. Methods: Medical records of horses that underwent exploratory celiotomy for colic were included when the skin was closed with NBC or SS and the horse survived ≥15 days after surgery. Records and a follow-up questionnaire were used to determine in-hospital and posthospital discharge incisional complications. ...
Theoret CL, Grahn BH, Fretz PB.Atresia of the nasal punctum is the most common congenital anomaly for the equine nasolacrimal system. Nasomaxillary dysplasia has not been previously documented in foals, is of unknown etiology, and appears to be a rare condition. Conjunctivomaxillary sinostomy was successful in resolving the epiphora.
Scherzer J, Davis C, Hurley DJ.The major difficulty in providing the benefits of embryo cryopreservation for equine agriculture is the mismatch between the optimal embryo age for collection from the mare (7-8 days after ovulation was detected) and the optimal age for freezing under current methods (6.5 days after ovulation). To overcome this limitation, we tested a method to enhance penetration of cryopreservative across the capsule and trophoblast of day 7 and 8 embryos combined with rapid freezing by vitrification. Six small embryos (<300 μm in diameter) were collected on day 6-7 after ovulation and twelve larger embryos...
Watanabe R, Huruta H, Ueno Y, Nukada T, Niwa H, Shinyashiki N, Kano R.Trichophyton equinum is a zoophilic dermatophyte that is frequently isolated from horse dermatophytosis and rare infections in humans. In the present study, molecular and physiological testing were performed on T. equinum isolates from dermatophytoses of Japanese racehorses to assess genotype and phenotype patterns of these strains. Comparative nucleotide sequence analysis showed that internal transcribed spacer (ITS) region sequences amplified from all Japanese isolates were 99.5% identical to T. equinum reference strains. ITS sequences amplified among the isolates were 100% (BT2) showed that...
Schenk I, Broussou D, Roques B, Lagershausen H, Machnik M, Röttgen H, Toutain PL, Thevis M.The combination of sulfadoxine (SDO) with trimethoprim (TMP) is widely used in veterinarian medicine. The aim of the present study was to compare excretion profiles and detection time windows of SDO and TMP in plasma and urine by means of a validated quantitative method. Eight horses received a single intravenous (i.v.) dose of 2.7 mg TMP and 13.4 mg SDO per kg bodyweight. Plasma and urine samples were collected up to 15 and 70 days post-administration, respectively. While urine samples underwent an enzymatic hydrolysis, plasma samples were proteolysed before further analysis. After solid-...
Rose RJ, Taylor BJ, Bellenger CR.The technique of internal fixation of intra-articular fractures of the third phalanx using lag screw interfragmentary compression is described. Three cases are discussed and the successful treatment of infection and osteomyelitis described in one of them. Despite this potential complication internal fixation offers a better prognosis and also a more rapid return to work than non-operative treatments.
Ahmed JS, Schmid G, Hörchner F.Pony peripheral blood lymphocytes (PBL) were stimulated with a soluble fraction of Trypanosoma (T.) evansi (SF). As determined by 3H-thymidine incorporation, the cells underwent a proliferative response and were able to: a) produce a factor having the biological activities of interleukin 2 (IL-2) since their supernatants could support the in vitro growth of pony PBL stimulated with concanavalin A (Con A-blasts); b) undergo a further proliferative response when incubated in short term cultures with SF, human recombinant IL-2 (hrIL-2), or both c) bind specifically radiolabelled hrIL-2 (125I-hrIL...
Foth PW, Scott VH, Mudge MC, Hurcombe SD.To determine an abdominal pressure cutoff value for intra-abdominal hypertension (IAH) in the horse and characterize IAH in horses with acute colic. Methods: Prospective clinical cohort. Methods: University teaching hospital. Methods: Nine healthy adult horses and 56 horses with acute colic. Methods: Ventral intra-abdominal pressure (IAP) was measured in triplicate at end expiration and averaged. Each colic case was classified as medical or surgical and large intestine (LI) or small intestine (SI). Management and final outcome (alive, euthanized, or died) were recorded. IAH was defined as ≥3...
Monin T.Physeal fractures of the tuber olecranon of 4 horses were treated, using the tension band method of compression fracture repair. A cortical bone screw and Steinmann pin were placed through the proximal fragment into the distal parent bone parallel to the palmar border of the olecranon. The tension band was placed dorsal to the Steinmann pin and anchored in a hole through the shaft of the ulna 10 cm distal to the tuber olecranon. Of the 4 foals, 2 became pasture sound, 1 is now being worked under saddle, and the 4th showed no signs of lameness 5 months after surgery.
Chesworth M, Brandenberger O, Cheetham J, Windley Z, Schumacher J, Cochran K, Piercy RJ, Perkins JD. To investigate the effect of the transverse arytenoid ligament (TAL) on abduction of the arytenoid cartilage when performing laryngoplasty. Modified prosthetic laryngoplasty was performed on right and left sides of 13 cadaver larynges. Increasing force was sequentially applied to the left arytenoid cartilage at 3 N intervals from 0-24 N, when the force on the right arytenoid cartilage was either 0 or 24 N, before and after TAL transection. Digital photographs of the rostral aspect of the larynx were used to determine the left arytenoid abduction angles for these given force combinations and ...
