Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Srivastava SK, Beutler E.1. Erythrocytes from normal and glucose 6-phosphate dehydrogenase-deficient humans were subjected to hydrogen peroxide diffusion to oxidize the GSH. Studies were carried out in the presence and absence of chromate to inhibit glutathione reductase and with or without the addition of glucose. 2. The GSH content of erythrocytes from other species was oxidized by subjecting them to hydrogen peroxide diffusion in the presence of chromate and glucose. 3. Chromate (1.3mm) inhibited glutathione reductase by about 80%, whereas glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, hexokin...
Bykovsky AF, Yershov FI, Zhdanov VM.Morphogenesis of Venezuelan equine encephalomyelitis virus was studied by means of electron microscopy. Virus-specific structures (factories, viroplasts) were found at early stages of infection; these structures were composed of fibrillar and cylindrical formations, aggregates of ribosomes, and viral nucleoids. The latter emerged from fibrillar and cylindrical structures. Aggregates of viral nucleoids were found in the cytoplasm and occasionally in the nuclei of virus-infected cells. Viral envelopes and mature virions were formed on the cell membranes and on the membranes of intracellular vacu...
Johnson AT, Soma LR, Ferouz C.Exercise-induced pulmonary hemorrhage (EIPH) affects a large portion of racing thoroughbred horses. Sites of hemorrhage and causal mechanisms remain unestablished. Our mathematical model was constructed to test the hypothesis that EIPH could be caused by a combination of respiratory and circulatory mechanical factors occurring during exercise. Various physiological data for respiration, blood circulation and exercise were incorporated into the model. Results show that inhalation pressure drops across airway resistances become great enough during exercise to cause rupture of capillaries for bot...
Davies HM.The relationships were explored between measurements of bone quality, size (quantity) and shape, and strain data collected during treadmill exercise at 4 and 12 m/s from the third metacarpal bones of 6 yearling and 6 mature Thoroughbred racehorses. Peak strains in yearling and mature Thoroughbred horses during exercise were related to the size and shape of the third metacarpal bone. The peak strains were significantly lower in horses with a greater cross-sectional area of bone and with a greater proportion of the bone in the dorsal cortex. There was no consistent relationship between peak stra...
Tellhelm B, Fritsch R, Reckels FJ.Requirements for optimal radiography of the horsetoe are described. Examples are given for getting X-rays of high quality under practice conditions, by using special intensifying screens and all the possibilities of radiological technique to guarantee a short exposure time.
Firth EC.In chondro-osseous disease in the foal there are three main categories of lesions: (i) synovitis alone (type S), (ii) synovitis accompanied by osteomyelitis originating in the epiphysis of the juxta-articular bone (type E) and (iii) synovitis accompanied by osteomyelitis originating directly adjacent to the physis of the juxta-articular bone (type P). Observations made in studies of the immature radius and metacarpus provide an explanation for the apparent predisposition of some joints for this disease. Relevant clinical and therapeutical aspects are discussed.
Sarkar P, McIntosh JM, Leavitt R, Gouthro H.Nimesulide is a nonsteroidal anti-inflammatory drug recently detected in equine blood and urine samples taken at the race track. The detection of the drug in a blood sample led to the identification of an unknown thin-layer chromatographic (TLC) spot in track urine samples as a metabolite of nimesulide. Characterization of the unknown TLC spot and comparison with the synthesized compound shows that the unknown TLC spot is a previously unreported equine metabolite of nimesulide. The metabolite was identified as resulting from the reduction of the nitro group on nimesulide to an amino group. Thi...
Jimenez Rihuete P, Villarino N, Pelisiak A, Rubio-Martinez LM.Refractometric determination of total protein (TP) in synovial fluid (SF) is commonly used for diagnosis and monitoring of synovial sepsis in horses. Previous studies have shown that elevated concentrations of certain anticoagulants may overestimate refractometric determination of TP concentration. Objective: The aim of the study was to evaluate the effect of different concentrations of dipotassium EDTA (KEDTA) and lithium heparin (LH) on TP determination by using a hand-held refractometer in equine synovial fluid. Methods: Cross-section observational study. Methods: Thirty samples of synovial...
Musselman EE, LoGuidice RJ.A necropsy diagnosis of hypoplastic left ventricular syndrome was made in a day-old foal. The cardiac abnormalities included mitral and aortic valve atresia, patent ductus arteriosus, and a secundum atrial septal defect. The left ventricle was hypoplastic and nonfunctional. The brief survival of the foal was a consequence of left-to-right shunting through the atrial septal defect and right-to-left shunting through the patent ductus. The information is presented to demonstrate the existence of the syndrome as a congenital defect in the horse and to clarify the necropsy findings for the practiti...
McCue PM, Matthews PM, Prell MJ, Bellone RR, Allen H.Genetic testing is required for the registration of foals of most equine breeds. Objective: To describe two clinical cases of marked delayed embryonic development or delayed fertilisation in pregnancies generated by embryo transfer. Methods: Case report. Methods: Donor mares were inseminated with semen from one stallion during one oestrous cycle and semen from a different stallion on the subsequent oestrous cycle. Embryo(s) were collected 8 days after ovulation during the second oestrous cycle and transferred into synchronised recipient mares. Genetic testing was performed to determine paren...
Butnev VY, Gotschall RR, Baker VL, Moore WT, Gout PW, Bousfield GR.Glycosylated equine prolactin (G-ePRL) and nonglycosylated ePRL were purified to homogeneity from side fractions obtained during isolation of LH/FSH from horse pituitaries. Both PRL forms were isolated together in high yield by the isolation procedure used for glycosylated porcine PRL/(G-pPRL) and pPRL, involving acetone extraction/precipitation, NaCl and isoelectric precipitation, and gel filtration. Purification of G-ePRL required additional Con A chromatography. The N-terminal amino acid sequencing for 32 cycles of G-ePRL and ePRL resulted in sequences identical to the known primary structu...
