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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
EcPV2 DNA in equine papillomas and in situ and invasive squamous cell carcinomas supports papillomavirus etiology.
Veterinary pathology    October 11, 2012   Volume 50, Issue 4 686-692 doi: 10.1177/0300985812463403
Lange CE, Tobler K, Lehner A, Grest P, Welle MM, Schwarzwald CC, Favrot C.Equine penile papillomas, in situ carcinomas, and invasive carcinomas are hypothesized to belong to a continuum of papillomavirus-induced diseases. The former ones clinically present as small grey papules, while the latter 2 lesions are more hyperplasic or alternatively ulcerated. To test the hypothesis that these lesions are papillomavirus-induced, samples of 24 horses with characteristic clinical and histologic findings of penile papillomas or in situ or invasive squamous cell carcinomas were collected. As controls, 11 horses with various lesions--namely, Balanoposthitis (6 cases), melanoma ...
Prevalence, intensity and seasonality of gastrointestinal parasites in abattoir horses in Germany.
Parasitology research    October 11, 2012   Volume 112, Issue 1 407-413 doi: 10.1007/s00436-012-3150-0
Rehbein S, Visser M, Winter R.Prevalence and intensity of gastrointestinal parasites were studied through a longitudinal survey in 400 horses over a 17-month period in an abattoir in Germany. Three hundred and ten horses (77.5 %) were demonstrated harbouring endoparasites either by direct recovery of parasites from the digestive tract and/or in terms of faecal egg counts (strongyles). The following parasites were found (percentage prevalence, range of counts): Gasterophilus intestinalis larvae (2.25 %, 1-154), Gasterophilus nasalis larvae (0.25 %, 44), Trichostrongylus axei (11.0 %, 1-3,620), Habronema majus (8.0 %; 1...
Sevoflurane inhibits equine myeloperoxidase release and activity in vitro.
Veterinary anaesthesia and analgesia    October 11, 2012   Volume 40, Issue 2 166-175 doi: 10.1111/j.1467-2995.2012.00786.x
Minguet G, de la Rebière G, Franck T, Joris J, Serteyn D, Sandersen C.To investigate the effects of the volatile anaesthetic sevoflurane on the release of total and active myeloperoxidase (MPO) by non-stimulated and stimulated polymorphonuclear neutrophils (PMNs) in whole blood from healthy horses. Methods: In vitro experimental study. Methods: Adult healthy horses. Methods: Samples of whole venous blood were collected and incubated in air or in air plus 2.3% or 4.6% sevoflurane for 1 hour. PMNs were stimulated with N-formyl-methionyl-leucyl-phenylalanine (fMLP), with a combination of cytochalasin B (CB) and fMLP or with phorbol myristate acetate (PMA). Total an...
Antibiotic susceptibility patterns of Crossiella equi and Amycolatopsis species causing nocardioform placentitis in horses. Erol E, Williams NM, Sells SF, Kennedy L, Locke SJ, Donahue JM, Carter CN.Nocardioform actinomycetes are significant causes of placentitis and abortions in horses. In the current study, antimicrobial susceptibility patterns of 38 Amycolatopsis spp. and 22 Crossiella equi isolates, the most common nocardioform actinomycetes causing placentitis in horses, were evaluated. Antimicrobial susceptibilities of these isolates were tested by broth microdilution method in a commercial system, which was designed for Nocardia spp., fast-growing Mycobacterium spp., and other aerobic actinomycetes. The minimum inhibitory concentration required to inhibit the growth of 90% of organ...
Evaluation of foal production following intracytoplasmic sperm injection and blastocyst culture of oocytes from ovaries collected immediately before euthanasia or after death of mares under field conditions.
Journal of the American Veterinary Medical Association    October 9, 2012   Volume 241, Issue 8 1070-1074 doi: 10.2460/javma.241.8.1070
Hinrichs K, Choi YH, Norris JD, Love LB, Bedford-Guaus SJ, Hartman DL, Velez IC.To evaluate the efficiency of foal production following intracytoplasmic sperm injection (ICSI) and blastocyst culture of oocytes from mares that died or were euthanized under field conditions. Methods: Prospective case series. Methods: 16 mares (age, 3 to 19 years) that died or were euthanized for various causes. Methods: Ovaries were collected immediately before euthanasia (n = 10) or after death (6). Ovaries were transported to the laboratory for oocyte recovery (15 mares), or oocytes were recovered at a remote location and shipped to the laboratory (1). Oocytes underwent ICSI, and presumpt...
Expression of inhibin/activin subunits in the equine uteri during the early pregnancy.
Reproduction in domestic animals = Zuchthygiene    October 9, 2012   Volume 48, Issue 3 423-428 doi: 10.1111/rda.12091
Zhang H, Nagaoka K, Imakawa K, Nambo Y, Watanabe G, Taya K, Weng Q.The establishment of equine pregnancy is a unique and long process during which a series of physical and possibly biochemical interactions are required between the conceptus and uterus. In this study, we investigated the expression pattern of inhibin/activin subunits in the uterus during early pregnancy. The uteri from four adult mares on cyclic day 13 or pregnancy day 25 were obtained. Immunohistochemical experiments suggested that inhibin/activin subunits were immunolocalized in the luminal and glandular epithelium on pregnancy day 25. In addition, the inhibin α and inhibin/activin βB subu...
The histological appearance of the proximal aspect of the dorsal condylar sagittal ridge of the third metacarpal and metatarsal bone in young warmblood horses: normal appearance and correlation with detected radiographic variations.
Anatomia, histologia, embryologia    October 8, 2012   Volume 42, Issue 3 232-238 doi: 10.1111/ahe.12006
Hauspie S, Forsyth R, Vanderperren K, Declercq J, Martens A, Saunders JH.The objective of this study is to describe the normal histological appearance of the dorsoproximal aspect of the sagittal ridge of the third metacarpal/metatarsal bone in young Warmblood horses, and to compare it to the different radiographic variations (irregular, indentation, lucency, notch) described at this level. A total of 25 metacarpo/metatarsophalangeal joints of 12 Warmblood horses were used. Five samples of each radiographically described group were selected for histological processing. Each category was compared with the normal control group. Each group showed a bone cortex, covered...
Effect of yohimbine on detomidine induced changes in behavior, cardiac and blood parameters in the horse.
Veterinary anaesthesia and analgesia    October 6, 2012   Volume 39, Issue 6 574-583 doi: 10.1111/j.1467-2995.2012.00776.x
DiMaio Knych HK, Covarrubias V, Steffey EP.To describe selected pharmacodynamic effects of detomidine and yohimbine when administered alone and in sequence. Methods: Randomized crossover design. Methods: Nine healthy adult horses aged 9 ± 4 years and weighing 561 ± 56 kg. Methods: Three dose regimens were employed in the current study. 1) 0.03 mg kg(-1) detomidine IV, 2) 0.2 mg kg(-1) yohimbine IV and 3) 0.03 mg kg(-1) detomidine IV followed 15 minutes later by 0.2 mg kg(-1) yohimbine IV. Each horse received all three treatments with a minimum of 1 week between treatments. Blood samples were obtained and plasma analyzed for detomidin...
Acute deterioration and death with necrotizing enteritis associated with Lawsonia intracellularis in 4 weanling horses.
Journal of veterinary internal medicine    October 5, 2012   Volume 26, Issue 6 1476-1480 doi: 10.1111/j.1939-1676.2012.01002.x
Page AE, Fallon LH, Bryant UK, Horohov DW, Luna TW, Marsh PS, Slovis NM, Sprayberry KA, Loynachan AT.No abstract available
Conjugal transfer of a virulence plasmid in the opportunistic intracellular actinomycete Rhodococcus equi.
Journal of bacteriology    October 5, 2012   Volume 194, Issue 24 6790-6801 doi: 10.1128/JB.01210-12
Tripathi VN, Harding WC, Willingham-Lane JM, Hondalus MK.Rhodococcus equi is a facultative intracellular, Gram-positive, soilborne actinomycete which can cause severe pyogranulomatous pneumonia with abscessation in young horses (foals) and in immunocompromised people, such as persons with AIDS. All strains of R. equi isolated from foals and approximately a third isolated from humans contain a large, ~81-kb plasmid which is essential for the intramacrophage growth of the organism and for virulence in foals and murine in vivo model systems. We found that the entire virulence plasmid could be transferred from plasmid-containing strains of R. equi (dono...
Active hyaluronidase 2 expression in the granulation tissue formed in the healing process of equine superficial digital flexor tendonitis.
The Journal of veterinary medical science    October 5, 2012   Volume 75, Issue 2 219-223 doi: 10.1292/jvms.12-0318
Yuda Y, Kasashima Y, Kuwano A, Sato K, Hattori S, Arai K.Upregulation of hyaluronidase 2 (HYAL2), one of somatic hyaluronidase (HAase), was demonstrated in granulation tissue during the healing of equine superficial digital flexor tendon injuries. The activity of HAase was assessed by hyaluronan (HA)-containing gel zymography and in situ zymography using frozen sections obtained from normal and injured tendon tissues. Elevated HAase activity was identified in the extract from the tendinopathic tissues, with lower levels of the activity in normal tendons. In situ zymography using fluorescently-labeled HA demonstrated HAase activity in the granulation...
Investigation of a non-invasive method of assessing the equine circadian clock using hair follicle cells.
Journal of circadian rhythms    October 5, 2012   Volume 10, Issue 1 7 doi: 10.1186/1740-3391-10-7
Watts LM, Browne JA, Murphy BA.A comprehensive understanding of the equine circadian clock involves the evaluation of circadian clock gene expression. A non-invasive and effective method for detecting equine clock gene expression has yet to be established. Currently, research surrounding this area has relied on collecting tissue biopsies or blood samples that can often be costly, time consuming and uncomfortable for the animal. Methods: Five mares were individually stabled under a light-dark (LD) cycle that mimicked the external environmental photoperiod during a time of year corresponding with the vernal equinox. Hair foll...
Kisspeptide in the estrous mare: is it an appropriate ovulation-inducing agent?
Theriogenology    October 5, 2012   Volume 78, Issue 9 1987-1996 doi: 10.1016/j.theriogenology.2012.07.012
Magee C, Bruemmer JE, Nett TM, Squires EL, Clay CM.Kisspeptides (KiSS) are a recently discovered family of neuropeptides with a central role in regulating the onset of reproductive function in all animals studied to date. We have established biological and physiological evidence for KiSS signaling in the mare. The objective of the current study was to evaluate the physiological and behavioral responses of mares repeatedly given the equine-specific kisspeptpin decapeptide (eKp-10, YRWNSFGLRY-NH(2)) in an effort to shorten the interovulatory period. Administration of eKp-10 (0.5 mg iv every 4 h) to mares beginning on Day 16 postovulation (Group ...
Optimization of leukocyte concentration in platelet-rich plasma for the treatment of tendinopathy.
The Journal of bone and joint surgery. American volume    October 4, 2012   Volume 94, Issue 19 e143(1-e143(8 doi: 10.2106/JBJS.L.00019
McCarrel TM, Minas T, Fortier LA.Numerous methods are available for platelet-rich plasma (PRP) generation, but evidence defining the optimum composition is lacking. We hypothesized that leukocyte-reduced PRP would result in lower inflammatory cytokine expression compared with concentrated-leukocyte PRP and that maintaining the platelet:white blood cell (WBC) ratio would compensate for the effect of increased WBC concentration. Methods: Blood and flexor digitorum superficialis tendons were collected from young adult horses. Three PRP groups were generated with the same platelet concentration but different WBC concentrations: i...
Serological and molecular detection of Theileria equi infection in horses in Hungary.
Veterinary parasitology    October 4, 2012   Volume 192, Issue 1-3 143-148 doi: 10.1016/j.vetpar.2012.09.035
Farkas R, Tánczos B, Gyurkovszky M, Földvári G, Solymosi N, Edelhofer R, Hornok S.The prevalence of Theileria equi infection was studied in 324 healthy horses from 27 farms in Hungary with cELISA and IFAT and the blood samples of 101 horses selected randomly were also examined by PCR. The results indicate that there are many stud farms where one or more horses are infected with T. equi. Among 27 farms 17 (67.9%) were found to have seropositive horses. The seroprevalence of theileriosis among the tested stud farms ranged between 0 and 100%. No marked differences were found in seropositivity between geographical areas. The overall prevalence of positive samples was 32.0% with...
Integration of genomic information into sport horse breeding programs for optimization of accuracy of selection.
Animal : an international journal of animal bioscience    October 4, 2012   Volume 6, Issue 9 1369-1376 doi: 10.1017/S1751731112000626
Haberland AM, König von Borstel U, Simianer H, König S.Reliable selection criteria are required for young riding horses to increase genetic gain by increasing accuracy of selection and decreasing generation intervals. In this study, selection strategies incorporating genomic breeding values (GEBVs) were evaluated. Relevant stages of selection in sport horse breeding programs were analyzed by applying selection index theory. Results in terms of accuracies of indices (r(TI) ) and relative selection response indicated that information on single nucleotide polymorphism (SNP) genotypes considerably increases the accuracy of breeding values estimated fo...
Use of a 3D dynamometric horseshoe for the measurement of grip parameters in a horse cantering on right and left circles on two surfaces.
Computer methods in biomechanics and biomedical engineering    October 4, 2012   Volume 15 Suppl 1 132-134 doi: 10.1080/10255842.2012.713656
Camus M, Chateau H, Holden-Douilly L, Robin D, Falala S, Ravary-Plumiöen B, Pourcelot P, Crevier-Denoix N.No abstract available
Effects of ground surface on the equine superficial digital flexor tendon loading at the walk and trot.
Computer methods in biomechanics and biomedical engineering    October 4, 2012   Volume 15 Suppl 1 143-144 doi: 10.1080/10255842.2012.713733
Ravary-Plumiöen B, Pourcelot P, Vergari C, Desquilbet L, Crevier-Denoix N.No abstract available
Use of motion trackers for equine locomotion analysis to implement a horse simulator.
Computer methods in biomechanics and biomedical engineering    October 4, 2012   Volume 15 Suppl 1 127-128 doi: 10.1080/10255842.2012.713609
Mager-Maury S, Biau S, Deslandes S.No abstract available
Equine superficial digital flexor tendon force and axial speed of sound: a calibration method under clinical conditions.
Computer methods in biomechanics and biomedical engineering    October 4, 2012   Volume 15 Suppl 1 12-13 doi: 10.1080/10255842.2012.713607
Vergari C, Pourcelot P, Ravary-Plumiöen B, Camus M, Holden-Douilly L, Falala S, Chateau H, Crevier-Denoix N.No abstract available
The influence of casein and urea as nitrogen sources on in vitro equine caecal fermentation.
Animal : an international journal of animal bioscience    October 4, 2012   Volume 6, Issue 7 1096-1102 doi: 10.1017/S1751731111002527
Santos AS, Ferreira LM, Martin-Rosset W, Cotovio M, Silva F, Bennett RN, Cone JW, Bessa RJ, Rodrigues MA.To access the fermentative response of equine caecal microbial population to nitrogen availability, an in vitro study was conducted using caecal contents provided with adequate energy sources and nitrogen as limiting nutrient. Two nitrogen (N) sources were provided, protein (casein) and non-protein (urea). Caecal fluid, taken from three cannulated horses receiving a hay-concentrate diet, was mixed with a N-free buffer-mineral solution. The influence of four N levels (3.7, 6.3, 12.5 or 25 mg of N in casein or urea) was studied using the gas production technique. Total volatile fatty acids (VFA)...
[New ‘community’ makes reporting horse diseases possible].
Tijdschrift voor diergeneeskunde    October 3, 2012   Volume 137, Issue 9 604-605 
Haneveld JK.No abstract available
[Horses are masters at compensating].
Tijdschrift voor diergeneeskunde    October 3, 2012   Volume 137, Issue 9 600 
van der Veen H.No abstract available
Comparison of isolation and expansion techniques for equine osteogenic progenitor cells from periosteal tissue. McD○ LA.Stem cell therapy and cell-based therapies using other progenitor cells are becoming the treatment of choice for many equine orthopedic lesions. Important criteria for obtaining autogenous equine progenitor cells in vitro for use in clinical cell-based therapy include the ability to isolate and expand cells repeatedly to high numbers (millions) required for therapy, in a clinically relevant time frame. Cells must also maintain their ability to differentiate into the tissue type of choice. The objective of this study was to compare isolation and expansion techniques for preparation of periostea...
Ultrasonographic visualization of colonic mesenteric vasculature as an indicator of large colon right dorsal displacement or 180° volvulus (or both) in horses.
The Canadian veterinary journal = La revue veterinaire canadienne    October 2, 2012   Volume 53, Issue 4 378-382 
Ness SL, Bain FT, Zantingh AJ, Gaughan EM, Story MR, Nydam DV, Divers TJ.Visualization of colonic mesenteric vasculature during transabdominal ultrasonographic examination of horses with colic can be a predictor of right dorsal displacement of the large colon or 180° large colon volvulus, or both. Medical records of 82 horses having had surgical treatment of colic and having received a transabdominal ultrasonographic examination on admission were reviewed. Colonic mesenteric vessels were sonographically identified coursing laterally on the right side of the abdomen in 24 of the 82 cases. Horses with colonic vessels identified on ultrasound were 32.5 times more lik...
Early experience with continuous positive airway pressure (CPAP) in 5 horses — a case series.
The Canadian veterinary journal = La revue veterinaire canadienne    October 2, 2012   Volume 53, Issue 4 426-429 
MacFarlane PD, Mosing M.This case series is the first report of the use of CPAP (continuous positive airway pressure) ventilation in adult horses. Two horses and 3 ponies anesthetized for orthopedic procedures in lateral recumbency received 10 cm H(2)O CPAP. During anesthesia, arterial oxygen partial pressure tended to increase and arterial carbon dioxide pressure tended to increase despite increased minute ventilation index. The measured cardiovascular parameters were within physiologic limits. Cette série de cas est le premier rapport sur l’utilisation de la ventilation spontanée en pression positive continue ...
Ethics of firing debated at BEVA congress.
The Veterinary record    October 2, 2012   Volume 171, Issue 13 312-314 doi: 10.1136/vr.e6500
Harris G.No abstract available
Treatment of equine sarcoids.
The Veterinary record    October 2, 2012   Volume 171, Issue 13 330 doi: 10.1136/vr.e6506
Scagliarini A, Bettini G, Savini F, Spadari A, Sonvico F, Balducci AG, Calbucci S, Colombo G.No abstract available
Intrathoracic pulsion diverticulum in a horse.
The Canadian veterinary journal = La revue veterinaire canadienne    October 2, 2012   Volume 53, Issue 4 408-411 
Yamout SZ, Magdesian KG, Tokarz DA, le Jeune SS.This is a report of a 12-year-old Swedish Warmblood gelding with a ruptured esophageal pulsion diverticulum associated with atypical clinical signs of colic and septic peritonitis on presentation. The location of this diverticulum at the hiatus was unique and was most likely responsible for the unusual presentation of this horse. Diverticule de Zenker intrathoracique chez un cheval. Ceci est un rapport d’un hongre de race Swedish Warmblood âgé de 12 ans présentant un diverticule de Zenker perforé associé à des signes cliniques atypiques de coliques et de péritonite septique à la pré...
MRI findings in 232 horses with lameness localized to the metacarpo(tarso)phalangeal region and without a radiographic diagnosis. King JN, Zubrod CJ, Schneider RK, Sampson SN, Roberts G.Two hundred and thirty-two horses with lameness localized to the metacarpo(tarso)phalangeal (MCP/MTP) region without a radiographic diagnosis were evaluated. All horses had high-field magnetic resonance (MR) imaging of the MCP/MTP region performed for the lame limb and the contralateral limb for comparison. There were 46 horses that had bilateral abnormalities in the forelimbs; 27 of these horses were not lame in the contralateral limb at the time of examination. Bilateral hind limb abnormalities were observed in 37 horses; 22 horses were not lame in the contralateral limb. Soft tissue abnorma...