The metacarpal bone in horses is a key component of the equine forelimb, consisting primarily of the third metacarpal bone, commonly referred to as the cannon bone, and the smaller second and fourth metacarpal bones, known as splint bones. These bones provide structural support and play a vital role in weight-bearing and locomotion. The third metacarpal bone is the largest and most prominent, extending from the carpus (knee) to the fetlock joint. Its strength and integrity are essential for the horse's ability to perform various physical activities. The second and fourth metacarpal bones are positioned on either side of the third metacarpal and are remnants of evolutionary development. They can be involved in conditions such as splints, where inflammation occurs due to stress or trauma. This page compiles peer-reviewed research studies and scholarly articles that explore the anatomy, function, and clinical aspects of metacarpal bones in horses, including their role in equine biomechanics and common pathologies.
Chateau H, Degueurce C, Denoix JM.To develop a method that allows quantification of the 3 anatomic rotations in the digital joints of moving horses and measure these rotations when horses are walking in a straight line on a hard track. Methods: 4 healthy French Trotter horses. Methods: Triads of ultrasonic kinematic markers were surgically linked to the 4 distal segments of the digits of the left forelimb of each horse. Three-dimensional (3-D) coordinates of these markers were recorded in horses walking in a straight line. The three angles of rotation of each digital joint were calculated by use of a joint coordinate system as...
Mattson S, Bouré L, Pearce S, Hurtig M, Burger J, Black W.To report tissue gentamicin concentrations after intraosseous (IO) perfusion in standing horses. Methods: In vivo study. Methods: Twelve horses. Methods: Sedated horses had a cannulated cortical bone screw inserted into the dorsolateral aspect of the treated metacarpus and a tourniquet applied proximally. Gentamicin (2.2 mg/kg) diluted in sterile saline solution (0.1 mL/kg) was infused through the screw. Two horses were euthanatized at each time interval: 0, 2, 6, 12, 24, and 36 hours. Synovial fluid and bone samples were collected distal to the screw from both forelimbs. Gentamicin concentrat...
Jenson PW, Gaughan EM, Lillich JD, Bryant JE.To determine clinical findings in and outcome of horses with fractures of the second or fourth metacarpal or metatarsal bone that underwent segmental ostectomy, leaving the proximal and distal portions of the bone undisturbed. Methods: Retrospective case series. Methods: 17 horses. Methods: Medical records were reviewed, and information on signalment, affected bone, lesion type, surgical procedure, amount of bone removed, and surgical and postsurgical complications was obtained. Follow-up information was obtained through telephone conversations with owners, trainers, and referring veterinarian...
Moure A, Reichmann P, Gamba HR.The application of the dual photon absorptiometry (DPA) technique, using gadolinium-153 as the photon source, to evaluate the bone mineral density (BMD) of the third metacarpal bone of horses is presented. The radiation detector was implemented with a NaI(TI) scintillator coupled to a 14 stage photomultiplier. A modular mechanical system allows the position of the prototype to be adjusted in relation to the animal. A moveable carrier makes it possible to scan the third metacarpal with a velocity adjustable between 1 and 12 mm s(-1), in steps of 1 mm s(-1), for a total distance of 250 mm. The p...
Da Costa Gómez TM, Radtke CL, Kalscheur VL, Swain CA, Scollay MC, Edwards RB, Santschi EM, Markel MD, Muir P.To determine whether bone microcracks are altered after application of focused and radial extracorporeal shock wave therapy (ESWT) to the equine distal limb. Methods: An ex vivo experimental model. Methods: A contralateral limb specimen was obtained from 11 Thoroughbred racehorses with a unilateral catastrophic injury. Distal limb specimens were also obtained from 5 non-racing horses. Methods: Three separate skin-covered bone segments were obtained from the mid-diaphysis of the metacarpus (MC3) or metatarsus (MT3). Focused (9,000 shockwaves, 0.15 mJ/mm2, 4 Hz) and radial (9,000 shockwaves, 0.1...
Stepnik MW, Radtke CL, Scollay MC, Oshel PE, Albrecht RM, Santschi EM, Markel MD, Muir P.To examine the fracture failure surfaces from Thoroughbred horses that had sustained a catastrophic condylar fracture. Methods: Bone specimens from the failure surface were obtained from 12 Thoroughbred racehorses with catastrophic injury and 2 non-racing horses with accidental long bone fracture. Methods: Bone specimens from the failure surface of each fracture were incubated with gold microspheres to label microcracks before examination at x50 to x60,000 using scanning electron microscopy. Microcracking at the failure surface was assessed using a visual analog scale. Results: Branching array...
Le Jeune SS, Macdonald MH, Stover SM, Taylor KT, Gerdes M.Objective-To determine whether partial transection of the medial branch of the suspensory ligament (MBSL) alters equine third metacarpal bone (MC3) condylar surface strains and forelimb, distal joint angles in a manner consistent with promotion of lateral condylar fracture. Study Design-In vitro biomechanical experiment. Sample Population-Right forelimbs from 7 Thoroughbred horse cadavers. Methods-Lateral and medial MC3 condylar, dorsal and abaxial, bone surface strains and distal joint angles were measured both before and after partial transection of the MBSL during in vitro axial limb compre...
Radtke CL, Danova NA, Scollay MC, Santschi EM, Markel MD, Da Costa Gómez T, Muir P.To determine changes in the distal ends of the third metacarpal and metatarsal bones (MCIII and MTIII) of Thoroughbred racehorses that had sustained a catastrophic condylar fracture during high-speed exercise. Methods: Fractured and contralateral MCIIIs and MTIIIs from 11 Thoroughbred racehorses that sustained a displaced condylar fracture during racing, both MCIIIs from 5 Thoroughbred racehorses euthanatized because of a catastrophic injury other than a condylar fracture, and both MCIIIs from 5 horses of other breeds that had not been professionally trained or raced. Methods: Macroscopic obse...
Carstanjen B, Lepage OM, Hars O, Langlois P, Duboeuf F, Amory H.The purpose of this longitudinal in-field study was to evaluate the influence of exercise, age, and gender on superficial cortical bone of the third metacarpal bone (MC III) in young Thoroughbreds by measuring speed of sound (SOS) values with an axial transmission technique (Omnisense, Sunlight Ltd, Israel). Both MC III of 75 racehorses, 2 to 4 years old, were monitored with SOS measurements in 5- to 7-week intervals during a 9- month physical exercise period. Medical data and training programs (slow gallop, canter, and high-speed work) of each horse were recorded. SOS measurements began befor...
Boyde A.This review presents findings made in studies of large mammalian bones, especially from racehorse training experiments (2-8 years old, third metacarpal, tarsal) and human autopsy orthopaedic femoral implant retrievals and other human biopsy and autopsy cases. Samples were cleaned to analyse mineralized matrix in three dimensions, or poly methyl-methacrylate embedded and micromilled to delete topography and study the superficial c. 0.5-microm two-dimensional section using quantitative backscattered electron imaging. With experimental implant studies in rabbits, observations were also made in vi...
Malone ED, Les CM, Turner TA.To report a severe form of carpometacarpal osteoarthritis (CMC-OA) affecting primarily older Arabian horses. Methods: Retrospective study. Methods: Thirty-one horses with CMC-OA. Methods: Carpal radiographs (405 sets) from 3 hospitals were evaluated to identify horses with marked osteoproliferative reaction across the medial aspect of the CMC joint. Owners were contacted to obtain detailed histories and status updates. Necropsy specimens of the CMC joint were evaluated at 2 hospitals to determine the prevalence of 2 variations in the articulation between the proximal second and third metacarpa...
Hiller LP, Stover SM, Gibson VA, Gibeling JC, Prater CS, Hazelwood SJ, Yeh OC, Martin RB.An important concept in bone mechanics is that osteons influence mechanical properties in several ways, including contributing to toughness and fatigue strength by debonding from the interstitial matrix so as to "bridge" developing cracks. Observations of "pulled out" osteons on fracture surfaces are thought to be indicative of such behavior. We tested the hypothesis that osteon pullout varies with mode of loading (fatigue vs. monotonic), cortical region, elastic modulus, and fatigue life. Mid-diaphseal beams from the dorsal, medial, and lateral regions of the equine third metacarpal bone were...
Hill AE, Carpenter TE, Gardner IA, Stover SM.To evaluate a Markov-chain model for the development of forelimb injuries in Thoroughbreds and to use the model to determine effects of reducing sprint distance on incidence of metacarpal condylar fracture (CDY) and severe suspensory apparatus injury (SSAI). Methods: Weekly exercise and injury data for 122 Thoroughbreds during racing or training. Methods: Weekly data were used to construct a Markov-chain model with 5 states (uninjured [UNINJ], palpable suspensory apparatus injury [PSAII, SSAI, CDY, and lost to follow-up [LOST]). Transition probabilities between UNINJ and PSAI were estimated as...
Carstanjen B, Duboeuf F, Detilleux J, Lepage OM.The purpose of this ex vivo study was to analyse two commonly established methods of mechanical bone property assessment for application in horses: Quantitative ultrasound (QUS), which depends on the bone's density and Young's modulus, and dual energy X-ray absorptiometry (DXA), which depends on the areal bone mineral density (BMD). The third metacarpal bone (MC III) of horses was selected as examination region for practical reasons. An interrelationship between QUS- and DXA-values was examined. Both MC III of eleven randomly selected equine cadavers were divided in nine regions of interest (R...
Zekas LJ, Forrest LJ.The purpose of this study was to describe ultrasonographic changes of the equine palmar metacarpal area attributed to the infiltration of local anesthetic solution and to determine whether these changes were noted immediately or at 24 h. The palmar metacarpal region of one forelimb in each of six horses was examined ultrasonographically with a 10-MHz linear array transducer and a 7.5-MHz curvilinear transducer. Transverse and longitudinal images were recorded at 5-cm intervals distal to the accessory carpal bone. High and low palmar and palmar metacarpal nerve blocks were performed with a 2% m...
Malik CL, Stover SM, Martin RB, Gibeling JC.Previous studies of the fracture properties of cortical bone have suggested that the fracture toughness increases with crack length, which is indicative of rising R-curve behavior. Based on this indirect evidence and the similarity of bone to ceramic matrix composites, we hypothesized that bone would exhibit rising R-curve behavior in the transverse orientation and that the characteristics of the R-curves would be regionally dependent within the cortex due to variations in bone microstructure and toughening mechanisms. To test these hypotheses, we conducted R-curve experiments on specimens fro...
Foreman JH, Kneller SK, Twardock AR, Chambers MD, Inoue OJ.Scintigraphy has been used in numerous clinical settings to examine horses to determine the origin of lameness problems, but it has not been used previously to monitor prospectively the skeletal responses of a group of similarly-trained racehorses. Our hypothesis was that in naïve Thoroughbred (TB) racehorses, initial treadmill training induces increased radiopharmaceutical uptake in high-motion joints and in the dorsal third metacarpal bone (MC3). Eight previously-untrained TB racehorses underwent sequential skeletal scintigraphic examinations as they exercised daily for 9 weeks on an inclin...
Birch HL, Smith TJ, Poulton C, Peiffer D, Goodship AE.Partial rupture occurs most often to the superficial digital flexor tendon (SDFT) of the forelimb at the mid-metacarpal level. In this study, we tested the hypothesis that the mid-metacarpal region of the SDFT has the smallest cross sectional area (CSA) and a similar collagen content to other regions and, therefore, represents a weak point in the tendon. The SDFT was collected from the forelimbs of 9 horses. Each tendon was marked at 7 different levels from the origin of the accessory ligament to the phalangeal region. The CSA, water content and collagen content was measured at each level. The...
Nielsen BD, O'Connor CI, Rosenstein DS, Schott HC, Clayton HM.The use of weight-training to alter bone strength has not been investigated in horses. Recognising that bone responds to loading, we studied the effect of carrying weight on bone development during training. Seventeen horses were divided into 3 groups: controls exercised counterclockwise in a free-flow exerciser; the weight group performed the same exercise carrying progressively increasing weight up to 45 kg and the weight supplement group also received a myo-anabolic supplement. Radiographic equivalence measure of bone mineral content of zones of the third metacarpi (MCIII) was determined on...
Davies HM.In Thoroughbred racehorses, the dorsal cortex (DC) of the third metacarpal bone (MC3) enlarges when horses are first exposed to fast exercise speeds. It is now possible to measure ultrasound speed through 3 to 5 mm depths of bone around the bone shaft using Sunlight Medical's 'Omnisense' machine. The aim of this experiment was to determine whether the ultrasound speed measured in the surface 3-5 mm of the midshaft dorsal cortex of MC3 could be related directly to the midshaft shape and size of the MC3s of young Thoroughbred racehorses at the same stage of training. Sixteen 2-year-old and sixte...
Carstanjen B, Lepage OM, Detilleux J, Duboeuf F, Amory H.To evaluate the usefulness of multisite quantitative ultrasonography for noninvasive assessment of bone in horses. Methods: 12 healthy horses and both forelimbs from 8 clinically normal horses. Methods: For in vivo measurements, various regions of interest (ROI) were examined on the third metacarpal bone, radius, and tibia. Precision error for speed of sound (SOS) measurements was obtained by measuring each ROI of 4 horses 10 times with probe repositioning. Additionally, 3 operators measured each aspect of the third metacarpal bone of 6 horses 5 times each. For ex vivo measurements, third meta...
Les CM, Stover SM, Keyak JH, Taylor KT, Kaneps AJ.Our hypothesis was that post-yield mechanical behavior of compact bone material in compression, defined as the stress, strain, or energy absorbed between 0.2% strain-offset and the point of maximum stress, is correlated with material density, modulus, strength, histomorphometric evidence of remodeling, and post-failure gross specimen morphology. Post-yield behavior of compact bone material from the third metacarpal bone of 10 horses, ages 5 months to 20 years, was investigated using single-load compression-to-failure. The post-yield stress, strain, and absorbed energy were compared with the co...
Galuppo LD, Stover SM, Aldridge A, Hewes C, Taylor KT.To compare monotonic mechanical properties of gap-ostectomized third metacarpal bones (MC3) stabilized with an MP35N interlocking nail system with contralateral intact bones. Methods: Twenty-four pairs of cadaveric equine MC3s. Methods: Third metacarpal bones were divided into 4 mechanical testing groups (6 pairs per group): compression, palmarodorsal (PD) and mediolateral (ML) 4-point bending, and torsion. One MC3 from each pair was randomly selected as an intact specimen, and the contralateral gap ostectomized bone was stabilized with a 4-hole, 14-mm-diameter, 250-mm-long, MP35N intramedulla...
Galuppo LD, Stover SM, Jensen DG.To compare bone fragment compression and the mechanical pushout strength and stiffness of 6.5-mm Acutrak Plus (AP) and 4.5-mm AO cortical (AO) bone screws after stabilization of a simulated equine third metacarpal (MC3) bone complete lateral condylar fracture. Methods: In vitro biomechanical paired study of screw insertion variables, bone fragment compression, and screw pushout tests using a bone screw stabilized simulated lateral condylar fracture model. Methods: Six pairs of cadaveric equine MC3s. Methods: Metacarpi were placed in a fixture and centered on a biaxial load cell in a materials ...
Andrea CR, Stover SM, Galuppo LD, Taylor KT, Rakestraw PC.To compare screw insertion characteristics and pullout mechanical properties between self-tapping (ST) and non-self-tapping (NST) AO 4.5-mm cortical bone screws in adult equine third metacarpal bone (MC3). Methods: In vitro biomechanical experiment. Methods: Seven pairs of adult equine MC3. Methods: Bicortical holes were drilled transversely in proximal metaphyseal, diaphyseal, and distal metaphyseal locations of paired MC3. NST screws were inserted in pre-tapped holes in 3 sites of one bone pair, and ST screws were inserted in non-tapped holes of contralateral MC3. Tapping and screw insertion...
van Harreveld PD, Lillich JD, Kawcak CE, Turner AS, Norrdin RW.To determine microradiographic appearance, bone histomorphometry, and mineral density of the long bones of the metacarpophalangeal joint in horses after immobilization followed by remobilization. Methods: 5 healthy horses. Methods: One forelimb of each horse was immobilized in a fiberglass cast for 7 weeks, followed by 8 weeks of increasing exercise. Calcein and oxytetracycline were administered IV during the immobilization and exercise phases, respectively, for bone labeling and analysis after euthanasia. Sagittal sections of metacarpal bones and proximal phalanges were examined via radiograp...
Riggs CM.Fractures are a common cause of loss among Thoroughbred racehorses. A large proportion of these injuries occurs in the absence of a specific traumatic event and show typical characteristics of stress fractures. The fractures show a high degree of consistency in their morphology; they frequently share the same locations as incomplete cracks and they are often associated with pre-existing pathology (periosteal and endosteal new bone formation and intracortical remodelling). Bone is able to adapt to changes in its mechanical environment. Studies of the Thoroughbred racehorse show modification of ...
Walter LJ, Davies HM.Accuracy and limitations of a radiographic technique were established for measurement of metacarpal bone shape in horses. A radiographic index (RI) has been used to measure changes in third metacarpal (Mc3) bone shape in response to training in young racehorses. The aim of these experiments was to determine the effects of positioning of the radiographic equipment on RI measurements from lateromedial radiographs of a left ex vivo metacarpus. Repeatability of the RI measurement in left lateromedial and right mediolateral view Mc3s were evaluated. The width of the dorsal cortex (DC), palmar corte...
Davies HM.The relationships were explored between measurements of bone quality, size (quantity) and shape, and strain data collected during treadmill exercise at 4 and 12 m/s from the third metacarpal bones of 6 yearling and 6 mature Thoroughbred racehorses. Peak strains in yearling and mature Thoroughbred horses during exercise were related to the size and shape of the third metacarpal bone. The peak strains were significantly lower in horses with a greater cross-sectional area of bone and with a greater proportion of the bone in the dorsal cortex. There was no consistent relationship between peak stra...
Ford TS, Ross MW, Orsini PG.Three techniques for inducing analgesia of the proximal metacarpal region were evaluated for the frequency of inadvertent injection into the middle carpal and carpometacarpal joints. Using methylene blue solution as a marker dye and 30 fresh cadaver specimens each, three clinicians performed either 30 infiltrations at the origin of the suspensory ligament (method A), 30 palmar and palmar metacarpal nerve blocks at the proximal end of the metacarpus (method B), or 30 palmar and palmar metacarpal nerve blocks at the distal aspect of the accessory carpal bone (method C). The frequency of inadvert...
Hanson PD, Markel MD.As more sophisticated research is performed to refine fracture fixation techniques for horses, it is important that normal values for the geometric properties of the bones of the appendicular skeleton be determined and that suitable controls be available. We evaluated the geometric properties of total bone width, cortical bone width, and medullary canal/trabecular bone width measured from 2 radiographic projections of equine long bones (humerus, radius, third metacarpal bone, femur, tibia, and third metatarsal bone) obtained from a general population of horses. Measurements were performed on s...
Gerdes C, Morgan R, Terry R, Foote A, Smith R.This descriptive anatomical study investigates the relationship between the third interosseous muscle, also known as the suspensory ligament, and the carpometacarpal joint in forelimbs of horses, with the hypothesis that there was a direct synovial communication between these structures as shown by computed tomographic arthrography, histology, and gross anatomy sections. Computed tomography of the carpus and metacarpal region was performed on two groups. Group 1 consisted of eight cadaver limbs undergoing computed tomographic arthrography following injection of a mixture of positive contrast m...
Nunamaker DM, Butterweck DM, Black J.In vitro local fatigue testing of the third metacarpal bone from Thoroughbred and Standardbred racehorses was performed, using fully reversed cyclic bending. Strain number of cycle data were accumulated and indicated that significant difference did not exist between the 2 breeds. It was concluded that the marked difference in the incidence of fatigue failure in the third metacarpal bone (bucked shins, dorsal metacarpal disease) seen in Thoroughbreds and Standardbreds was not related to any differences between the 2 breeds in mechanical properties of the bone.
Bertone AL, Park RD, Turner AS.Radiographs of 23 foals (35 forelimbs) with carpal region angular limb deformities, which later were corrected by hemicircumferential transection of the periosteum and periosteal stripping, were evaluated as to geometric and morphologic abnormalities. Geometric evaluation included deviation angle and deviation pivot point. Morphologic abnormalities were categorized as: asymmetric width of the distal radial physis; asymmetric width of the distal radial epiphysis; carpal bone collapse or fracture; carpal bone hypoplasia; carpal bone displacement; and metacarpal bone displacement. Fifty-seven per...
Carstanjen B, Lepage OM, Hars O, Langlois P, Duboeuf F, Amory H.The purpose of this longitudinal in-field study was to evaluate the influence of exercise, age, and gender on superficial cortical bone of the third metacarpal bone (MC III) in young Thoroughbreds by measuring speed of sound (SOS) values with an axial transmission technique (Omnisense, Sunlight Ltd, Israel). Both MC III of 75 racehorses, 2 to 4 years old, were monitored with SOS measurements in 5- to 7-week intervals during a 9- month physical exercise period. Medical data and training programs (slow gallop, canter, and high-speed work) of each horse were recorded. SOS measurements began befor...
Lescun TB, Adams SB, Main RP, Nauman EA, Breur GJ. The objectives of this study were to validate a finite element model of the equine distal limb transfixation cast and to determine the effect of six transcortical pin parameters on bone-pin interface (BPI) stresses in the third metacarpal bone. Methods: A transfixation cast finite element model was developed from a computed tomography scan of the third metacarpal bone and modelled pin elements. The model was validated by comparing strain measured around a 6.3-mm transfixation pin in the third metacarpal bone with the finite element model. The pin parameters of diameter, number, location,...
Merritt JS, Davies HM.Bending of the equine metacarpal bones during locomotion is poorly understood. Cantilever bending, in particular, may influence the loading of the metacarpal bones and surrounding structures in unique ways. Objective: We hypothesised that increased amounts of sagittal-plane cantilever bending may govern changes to the shape of the metacarpal bones of Thoroughbred racehorses during training. We hypothesised that this type of bending would require a linear change to occur in the combined second moment of area of the bones for sagittal-plane bending (I) during race training. Methods: Six Thorough...
Mattson SE, Pearce SG, Bouré LP, Dobson H, Hurtig MB, Black WD.To describe and compare the distribution of technetium Tc 99m (99mTc) pertechnate following intraosseous or i.v. injection (with or without use of a tourniquet) in the distal portion of the forelimb in standing horses. Methods: 4 horses. Methods: Each horse received 4 forelimb treatments in random sequence: intraosseous infusion with tourniquet application (IOT), intraosseous infusion without tourniquet application, i.v infusion with tourniquet application (IVT), and i.v. infusion without tourniquet application. Dynamic nuclear scintigraphic imaging of the third metacarpal bone, proximal and m...
McClure SR, Watkins JP, Ashman RB.Breaking strength (torque at failure) of equine third metacarpal bones, with transfixation pins placed parallel in the frontal plane and 30 degrees divergent from the frontal plane, was determined in vitro. Two transfixation pins were placed through the distal metaphysis, using a jig designed to drill the holes in the assigned configuration. Paired metacarpal bones II through IV from 12 horses were tested in torsion. The torsional moment of the force applied through the transfixation pins at failure was compared for each limb. Metacarpal bones with divergent pins were significantly (P = 0.030)...
Batson EL, Reilly GC, Currey JD, Balderson DS.The metacarpal of the horse is severely loaded during vigorous exercise. Metacarpal specimens have a greater impact strength in young horses that have been exercised than in those that have only been walked. We did not find a corresponding difference in the radius of the same horses. We show that cranial (anterior) cortical bone from the radius, which is loaded in tension during locomotion, has a greater Young's modulus, and tensile and bending strength, than bone from the caudal (posterior) cortex, which is loaded in compression. Caudal bone is, however, stronger in compression. The differenc...
Jackson M, Geyer H, Fürst A.This study concerns the vestigial metacarpal and metatarsal bones, so called splint bones. The soft tissues, which stabilize the splint bones were carefully examined. The palmar metacarpal/plantar metatarsal fascia, the metacarpal/metatarsal interosseous ligaments and the fibres, which exit distally from the splint bone, were examined in depth. Cadaveric distal limbs were collected from 5 slaughtered or euthanized horses. The legs were examined both, microscopically and macroscopically. The palmar metacarpal/plantar metatarsal fascia is a very stable structure, which connects the splint bone w...
Nunamaker DM, Richardson DW, Butterweck DM.Plate luting, a technique that uses polymethylmethacrylate (PMMA) interposed between the plate and the bone, as well as between the screw heads and the plate, to improve the stability of internal fixation was tested in vitro using 20 paired equine third metacarpal bones with mid-diaphyseal osteotomies plated with six-hole broad ASIF compression plates. One of each pair was luted and all specimens were tested in static overload or cyclic loading at 75% of the ultimate breaking strength using four-point bending. Although no differences were measured in static overload tests between luted and non...
Symons JE, Entwistle RC, Arens AM, Garcia TC, Christiansen BA, Fyhrie DP, Stover SM.To determine morphological and mechanical properties of trabecular bone of horses with a bone fragility syndrome (BFS; including silicate-associated osteoporosis). Methods: Cylindrical trabecular bone samples from the distal aspects of cadaveric third metacarpal bones of 39 horses (19 horses with a BFS [BFS bone samples] and 20 horses without a BFS [control bone samples]). Methods: Bone samples were imaged via micro-CT for determination of bone volume fraction; apparent and mean mineralized bone densities; and trabecular number, thickness, and separation. Bone samples were compressed to failur...
Jenson PW, Gaughan EM, Lillich JD, Bryant JE.To determine clinical findings in and outcome of horses with fractures of the second or fourth metacarpal or metatarsal bone that underwent segmental ostectomy, leaving the proximal and distal portions of the bone undisturbed. Methods: Retrospective case series. Methods: 17 horses. Methods: Medical records were reviewed, and information on signalment, affected bone, lesion type, surgical procedure, amount of bone removed, and surgical and postsurgical complications was obtained. Follow-up information was obtained through telephone conversations with owners, trainers, and referring veterinarian...
Dallap BL, Bramlage LR, Embertson RM.The purpose of this study was to evaluate screw fixation with cortical drilling as a surgical treatment for dorsal cortical stress fractures of MCIII in the Thoroughbred racehorse. Details of age, sex, limb affected, fracture assessment, and post operative recommendations were obtained from medical records and radiographs. Fracture healing was assessed radiographically at the time of screw removal. Performance evaluation was determined from race records obtained from The Jockey Club Information System, Lexington, Kentucky. Fifty-six Thoroughbred racehorses were treated surgically for stress fr...
Trope GD, Ghasem-Zadeh A, Anderson GA, Mackie EJ, Whitton RC.High-resolution 3D imaging may improve the prediction and/or early identification of condylar fractures of the distal metacarpus/tarsus and reduce the frequency of breakdown injury in racehorses. Objective: To test the hypotheses that horses suffering condylar fractures have higher bone volume fraction (BV/TV) of the distal metacarpal epiphysis, greater subchondral bone thickness at the fracture site and higher second moment of inertia in the metacarpal midshaft as identified with high-resolution 3D imaging. Methods: Cross-sectional study using cadaver material. Methods: Thoroughbreds that die...
Pagliara E, Marenchino M, Antenucci L, Costantini M, Zoppi G, Giacobini MDL, Bullone M, Riccio B, Bertuglia A.Fetlock joint angle (FJA) pattern is a sensitive indicator of lameness. The first aim of this study is to describe a network of inertial measurement units system (IMUs) for quantifying FJA simultaneously in all limbs. The second aim is to evaluate the accuracy of IMUs for quantifying the sagittal plane FJA overground in comparison to bi-dimensional (2-D) optical motion capture (OMC). 14 horses (7 free from lameness and 7 lame) were enrolled and analyzed with both systems at walk and trot on a firm surface. All enrolled horses were instrumented with 8 IMUs (a pair for each limb) positioned at t...
Ross MW, Ford TS, Orsini PG.Seven horses, 2 to 4 years of age, were examined because of moderate-to-severe forelimb lameness, mild effusion of the middle carpal joint (3 horses), and pain on palpation of the origin of the suspensory ligament (4 horses). The lameness was abolished by anesthetic infiltration of the middle carpal joint in six horses. In four of them, a high palmar nerve block also abolished the lameness. A linear radiolucency in the proximal end of the third metacarpal bone (McIII) was interpreted as an incomplete longitudinal fracture. In one horse, distinct intramedullary sclerosis limited to the palmar c...
Bassage LH, Richardson DW.To determine type, distribution, and radiographic appearance of condylar fractures of the third metacarpal bone (MC-3) or third metatarsal bone (MT-3) in Thoroughbreds (TB), Standardbreds (SB), and Arabians, to assess long-term outcome of horses in which fractures were repaired surgically, and to identify variables associated with prognosis for return to racing. Methods: Retrospective study. Methods: 224 horses with 233 fractures. Methods: Medical records and radiographs obtained before and after treatment were reviewed. Racing performance before and after treatment was determined by reviewing...
Hauspie S, Forsyth R, Vanderperren K, Declercq J, Martens A, Saunders JH.The objective of this study is to describe the normal histological appearance of the dorsoproximal aspect of the sagittal ridge of the third metacarpal/metatarsal bone in young Warmblood horses, and to compare it to the different radiographic variations (irregular, indentation, lucency, notch) described at this level. A total of 25 metacarpo/metatarsophalangeal joints of 12 Warmblood horses were used. Five samples of each radiographically described group were selected for histological processing. Each category was compared with the normal control group. Each group showed a bone cortex, covered...
Tirosh-Levy S, Perl S, Valentine BA, Kelmer G.Hepatoblastoma was diagnosed in a 3-year-old Thoroughbred gelding presented with forelimb lameness with bilateral fatigue fractures of the proximal third metacarpal bones. An abdominal mass was detected on ultrasound examination of the abdomen. Absolute erythrocytosis was diagnosed after clinical and haematological evaluation. The fractured metacarpal bones were surgically removed but complications after surgery were fatal. The liver mass was diagnosed as a hepatoblastoma based on histology and immunochemical staining. The combination of hepatoblastoma and fatigue fractures has not been descri...
Lewis AJ, Sod GA, Burba DJ, Mitchell CF.To compare compression pressure (CP) of 6.5 mm Acutrak Plus (AP) and 4.5 mm AO cortical screws (AO) when inserted in simulated lateral condylar fractures of equine 3rd metacarpal (MC3) bones. Methods: Paired in vitro biomechanical testing. Methods: Cadaveric equine MC3 bones (n=12 pair). Methods: Complete lateral condylar osteotomies were created parallel to the midsagittal ridge at 20, 12, and 8 mm axial to the epicondylar fossa on different specimens grouped accordingly. Interfragmentary compression was measured using a pressure sensor placed in the fracture plane before screw placement for ...
Donabedian M, Delguste C, Perona G, Lebecque P, Duboeuf F, Lepaga O, Martin-Rosset W.Bone mineral density (BMD) is correlated to mechanical properties of bone. In the horse, dual energy X-ray absorptiometry (DXA) has yet only been performed ex-vivo, but a new portable DXA device would be ideal for in-vivo BMD measurement. We explored field suitability, precision and accuracy of this device for in-vivo third metacarpal density assessment. Precision was analysed by calculating measurement variation under repeated measurement tests with (reproducibility) and without (repeatability) limb repositioning. Repeatability and reproducibility were tested ex-vivo, at the same time that in...
Sod GA, Riggs LM, Mitchell CF, Martin GS, Gill MS.To compare the monotonic biomechanical properties and fatigue life of a 5.5-mm-broad locking compression plate (5.5 LCP) fixation with a 4.5-mm-broad locking compression plate (4.5 LCP) fixation to repair osteotomized equine 3rd metacarpal (MC3) bones. Methods: In vitro biomechanical testing of paired cadaveric equine MC3 with a middiaphyseal osteotomy, stabilized by 1 of 2 methods for fracture fixation. Methods: Fifteen pairs of adult equine cadaveric MC3 bones. Methods: Fifteen pairs of equine MC3 were divided into 3 test groups (5 pairs each) for (1) 4-point bending single cycle to failure ...
Spriet M, Arndt S, Pige C, Pye J, O'Brion J, Carpenter R, Blea J, Dowd JP.This retrospective, methods comparison study aimed to compare skeletal scintigraphy and F-NaF positron emission tomography (PET) for the detection of abnormalities in the fetlocks of Thoroughbred racehorses. Thirty-three horses (72 limbs) imaged with both scintigraphy and F-NaF PET, for investigation of lameness or poor performance related to the fetlock, were included. Seven observers, including experienced racetrack practitioners, surgery and imaging residents, and a board-certified veterinary radiologist, independently reviewed all data for evidence of increased radiopharmaceutical uptake...
Les CM, Keyak JH, Stover SM, Taylor KT.Three-dimensional finite element (FE) models of the left metacarpi of five adult horses were developed from quantitative computed tomography data, using the algorithms of Keyak et al. (1990, J Biomed. Engng 12, 389-397). The metacarpi were then equipped with 12 rosette strain gauges and loaded non-destructively in a mechanical testing machine. The bones and the models were loaded in axial compression, with the load evenly distributed across the distal row of carpal bones, and with a point load placed mediad to the sagittal midline, to a load equivalent to three times body weight (-15 kN); and ...
Lescun TB, Hoffseth K, Yang HT, Hansma PK, Kopeikin HS, Chandrasekar S.To compare results obtained with a handheld reference point indentation instrument for bone material strength index (BMSi) measurements in the equine third metacarpal bone for various testing conditions. Methods: 24 third metacarpal bones. Methods: Third metacarpal bones from both forelimbs of 12 horses were obtained. The dorsal surface of each bone was divided into 6 testing regions. In vivo and ex vivo measurements of BMSi were obtained through the skin and on exposed bone, respectively, to determine effects of each testing condition. Difference plots were used to assess agreement between BM...
Nagy A, Bodò G, Dyson SJ, Compostella F, Barr AR.Evidence-based information is limited on distribution of local anaesthetic solution following perineural analgesia of the palmar (Pa) and palmar metacarpal (PaM) nerves in the distal aspect of the metacarpal (Mc) region ('low 4-point nerve block'). Objective: To demonstrate the potential distribution of local anaesthetic solution after a low 4-point nerve block using a radiographic contrast model. Methods: A radiodense contrast medium was injected subcutaneously over the medial or the lateral Pa nerve at the junction of the proximal three-quarters and distal quarter of the Mc region (Pa inject...
Westermann S, Windsteig V, Schramel JP, Peham C.To determine the skin temperature of the metacarpus in horses associated with the use of bandages and tendon boots, compared with the bare limb, at rest and after 20 minutes of lunging. Methods: 10 adult horses. Methods: Skin temperature on the bare metacarpus of both forelimbs was measured at rest and after lunging. Subsequently, a bandage was applied to the left metacarpus and a tendon boot to the right metacarpus and skin temperature was measured at rest and after lunging. Skin temperature was measured with fixed sensors and thermographically. Results: Mean ± SD skin temperatures of the ba...
