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Topic:Necropsy

Necropsy, also known as an autopsy, is a systematic examination of a horse's body after death to determine the cause of death and evaluate any disease or injury. This procedure involves a thorough assessment of the horse's organs and tissues, often including histopathological analysis to identify abnormalities at the microscopic level. Necropsy can provide valuable insights into equine health issues, contributing to a better understanding of disease processes, management practices, and potential preventive measures. This page compiles peer-reviewed research studies and scholarly articles that explore the methodologies, findings, and implications of necropsy in equine veterinary science.
Occipitoatlantoaxial malformation in two non-Arabian horses.
Journal of the American Veterinary Medical Association    July 1, 1985   Volume 187, Issue 1 36-40 
Wilson WD, Hughes SJ, Ghoshal NG, McNeel SV.Occipitoatlantoaxial malformation was diagnosed in a 19-month-old mare of Appaloosa breeding and in a 3-year-old Quarter Horse gelding. Both horses had abnormal head and neck carriage since birth, but neurologic deficits did not become evident clinically until the horses reached 2 and 3 years of age, respectively. Palpation and manipulation of the base of the skull and cervical area proved to be useful diagnostically. Movement could not be elicited at the atlantooccipital joint but, in comparison with clinically normal horses, the range of dorsoventral motion at the atlantoaxial joint was incr...
Intestinal decompression: preliminary study in the horse.
Journal of the American Veterinary Medical Association    June 15, 1985   Volume 186, Issue 12 1304-1309 
Beroza GA, Donawick WJ, Topkis VA.A technique of nasoduodenal (N-D) intubation and intestinal decompression was developed and used in the horse to explore the prevention of gastric and intestinal distention after abdominal surgical operation. Three styles of tubes (2 single-lumen tubes and 1 double-lumen tube) were positioned in the duodenum of 12 mature horses (10 experimental and 2 clinical) during laparotomy (without enterotomy), and an iatrogenic occlusion at the small intestine was created and later released in the 10 experimental horses. The 2 clinical horses had an exploratory laparotomy to correct a natural obstruction...
Pelvic limb lameness due to malignant melanoma in a horse.
Journal of the American Veterinary Medical Association    June 1, 1985   Volume 186, Issue 11 1215-1217 
Kirker-Head CA, Loeffler D, Held JP.Malignant melanoma in a 21-year-old, gray, Arabian gelding was manifested by rapidly deteriorating lameness of the right pelvic limb. A melanotic, cutaneous mass of small dimensions was identified in the left jugular furrow. Exploratory laparoscopy revealed widespread infiltration of melanotic masses into the structures of the abdominal cavity. Necropsy indicated the lameness to have resulted from infiltration of neoplastic cells into the sacral nerves, dorsal root ganglia, proximal ischiatic nerve, and gluteal muscle fibers. The primary tumor could not be identified.
Comparison of three suture techniques for anastomosis of the small intestine in the horse.
American journal of veterinary research    June 1, 1985   Volume 46, Issue 6 1282-1286 
Dean PW, Robertson JT.Seven horses were used to compare the Gambee, the crushing, and a 2-layer inverting suture pattern composed of a simple continuous layer in the mucosa oversewn with a continuous Lembert pattern in the seromuscular layer. Horses were evaluated at 30 days for adhesion formation, lumen diameter, and quality of healing at the anastomotic sites. One horse was euthanatized 9 days after surgery after 24 hours of ileus and colic; necropsy revealed septic peritonitis and widespread adhesions. One horse had no adhesions. The remaining horses had adhesions associated with 50% of the Gambee and 50% of the...
Prevalence and epidemiology of the major gastrointestinal parasites of horses in Perth, Western Australia.
Equine veterinary journal    May 1, 1985   Volume 17, Issue 3 208-213 doi: 10.1111/j.2042-3306.1985.tb02472.x
Dunsmore JD, Jue Sue LP.A survey was conducted on the prevalence of the major gastrointestinal parasites in 140 horses necropsied in Perth, Western Australia, during 1979 to 1982. Adult Strongylus vulgaris were found in 22.5 per cent of horses and verminous arteritis in 62.9 per cent. The peak worm prevalence was in November to January (summer). S edentatus had a similar prevalence and seasonality but S equinus was not found in this survey. Draschia megastoma and Habronema muscae were found in 66.2 per cent and 35.3 per cent of horses respectively. Infection is probably acquired in summer when 8 per cent of the Musca...
Integrated control of Strongylus vulgaris infection in horses using ivermectin.
Equine veterinary journal    May 1, 1985   Volume 17, Issue 3 191-195 doi: 10.1111/j.2042-3306.1985.tb02466.x
Dunsmore JD.An attempt was made to control or eliminate Strongylus vulgaris from a closed group of three horses at pasture near Perth, Western Australia, by dosing with ivermectin on four occasions during the time of year when it was believed that environmental conditions would eliminate all the non-parasitic stages of that species. At necropsy, five months after the last dose of anthelmintic and after continually grazing the same pastures, no S vulgaris or arterial lesions were found in those horses and S edentatus, Draschia megastoma and Habronema species were also almost completely eliminated.
Chronic eosinophilic pancreatitis and ulcerative colitis in a horse.
Journal of the American Veterinary Medical Association    April 15, 1985   Volume 186, Issue 8 809-811 
Breider MA, Kiely RG, Edwards JF.A generalized debilitating disease in a horse was believed to be related to hypersensitivity to migrating strongyle larvae. The clinical signs included weight loss, diarrhea, and ulcers on all 4 coronary bands. The mare's condition deteriorated rapidly, so the mare was euthanatized and necropsied. The major histopathologic findings were chronic multifocal eosinophilic pancreatitis, hepatic portal fibrosis, biliary hyperplasia, and chronic ulcerative eosinophilic colitis. This case was similar to previously reported cases of chronic eosinophilic gastroenteritis in horses. Although the etiologic...
Pathologic changes associated with induced small intestinal strangulation obstruction and nonstrangulating infarction in horses.
American journal of veterinary research    April 1, 1985   Volume 46, Issue 4 913-916 
Sullins KE, Stashak TS, Mero KN.Arteriovenous (ischemic strangulation obstruction, ISO) or venous (hemorrhagic strangulation obstruction, HSO) occlusions were created in the jejunum of 5 anesthetized horses and were left in situ for 1-, 2-, or 3-hour intervals. Segments were evaluated grossly for color, thickness, and motility. The horses were euthanatized, and the degree of mucosal slough, edema, congestion, and hemorrhage was determined histologically. Segments subjected to ISO became dark, but did not contain edema or hemorrhage. Segments subjected to HSO were characterized by progressive congestion, edema, and hemorrhage...
Parasites in lungs of dead equids in Kentucky: emphasis on Dictyocaulus arnfieldi.
American journal of veterinary research    April 1, 1985   Volume 46, Issue 4 924-927 
Lyons ET, Tolliver SC, Drudge JH, Swerczek TW, Crowe MW.Prevalence of natural infections of parasites from the lungs of 488 dead Thoroughbreds in Kentucky was investigated. The horses varied from 1 to 32 years of age; 419 horses were from 215 farms and 69 horses were from 68 individual sources for which a specific farm was not identified. Examinations of the lungs were made from Mar 1, 1983 through Feb 29, 1984. Dictyocaulus arnfieldi was recovered from 56 (11%) of the horses. Other parasites found were larvae of Parascaris equorum in 37 (8%) and of Habronema/Draschia in 67 (14%) of the horses. The possible effect of ivermectin treatment on the pre...
Ataxia and weakness associated with fourth ventricle vascular anomalies in two horses.
Journal of the American Veterinary Medical Association    March 15, 1985   Volume 186, Issue 6 601-603 
Miller LM, Reed SM, Gallina AM, Palmer GH.Two adult horses with progressive neurologic signs were examined clinically and at necropsy. Both horses had signs of progressive ataxia and weakness, clinically diagnosed as spinal cord in origin. Differential diagnoses for cervical spinal ataxia in horses included cervical vertebral malformation, equine degenerative myeloencephalopathy, equine herpes-virus-I myeloencephalopathy, and equine protozoal myeloencephalopathy. Necropsy findings in both horses were similar and consisted of a large hematoma in the fourth ventricle, with upward compression of the cerebellum and downward compression of...
Clinical and radiographic findings in Corynebacterium equi pneumonia of foals.
Journal of the American Veterinary Medical Association    March 15, 1985   Volume 186, Issue 6 593-599 
Falcon J, Smith BP, O'Brien TR, Carlson GP, Biberstein E.Thirty-nine foals with pneumonia were admitted to the Veterinary Medical Teaching Hospital at the University of California, Davis. Corynebacterium equi was recovered from each of them on bacteriologic culture of transtracheal aspiration specimens or lung specimens at necropsy. The foals were divided into 2 groups. Group I consisted of 20 foals that died because of C equi pneumonia and were subsequently necropsied. Group II consisted of 19 foals that were treated and discharged from the hospital. Radiography was performed on all foals. Clinical signs included increased respiratory rate, fever, ...
Prevalence of some internal parasites recovered at necropsy of Thoroughbreds born in 1982 in Kentucky.
American journal of veterinary research    March 1, 1985   Volume 46, Issue 3 679-683 
Lyons ET, Tolliver SC, Drudge JH, Swerczek TW, Crowe MW.A total of 89 Thoroughbreds, 14 to 333 days old (born in 1982), were examined at necropsy for certain internal parasites during a 1-year-period, Mar 1, 1982, to Feb 28, 1983. The eyes of 73 of the horses and the cranial mesenteric arteries of 71 were examined. Specific interest was on prevalence of parasites according to month of the year and age of the horses at necropsy. Parasites recovered (first month-last month infected horse found) were as follows: Thelazia lacrymalis (eyes) immature and mature (June - February); Habronema/Draschia (lungs) immature (May - September); Habronema muscae (st...
Equine congenital defects.
American journal of veterinary research    February 1, 1985   Volume 46, Issue 2 353-358 
Crowe MW, Swerczek TW.In a 13-year survey of equine congenital defects that resulted in death or required euthanasia in central Kentucky, necropsies were performed on 608 deformed fetuses or newborn foals. The following congenital anomalies were observed: contracted foal syndrome (33.2%), miscellaneous limb contraction (20%), multiple defects (5.3%), microphthalmia (4.6%), craniofacial malformations (4.3%), cleft palate (4.0%), heart defects (3.5%), umbilical defects (3.5%), and hydrocephalus (3.0%). Eleven less frequently occurring anomalies constituted the balance of the congenital defects in fetuses and newborn ...
Spontaneous craniofacial malformations and central nervous system defects in an aborted equine foetus.
Journal of comparative pathology    January 1, 1985   Volume 95, Issue 1 131-135 doi: 10.1016/0021-9975(85)90086-6
Bunton TE.Developmental defects are rarely reported in the horse. Severe craniofacial and central nervous system defects in an equine foetus are described and their possible causation and pathogenesis are suggested.
Activity of closantel in the prevention of Gasterophilus and Strongylus vulgaris larval infections in equine foals and yearlings.
American journal of veterinary research    January 1, 1985   Volume 46, Issue 1 16-18 
Guerrero J, Newcomb K, Seibert BP, Michael BF.Two controlled tests were conducted in equine foals and yearlings to determine the optimal oral dosage and the duration of activity of closantel for the prevention of Gasterophilus spp larval infections. Additional data were collected on the activity of closantel against Strongylus vulgaris larval infections. In experiment 1, 12 foals and 12 yearlings were equally allocated to 4 experimental groups, and were given oral treatments with closantel at dosages of 0 (nontreated controls), 2, 5, or 8 mg/kg of body weight every 2 months during bot season. The foals and yearlings were allowed to graze ...
Some unusual features of mesangioproliferative glomerulonephritis in horses.
Veterinary pathology    November 1, 1984   Volume 21, Issue 6 574-581 doi: 10.1177/030098588402100605
Sabnis SG, Gunson DE, Antonovych TT.Seven horses ranging from three to 15 years of age had nephrotic syndrome; at necropsy, renal tissue of all seven horses had the morphologic lesions of mesangioproliferative glomerulonephritis (membranoproliferative glomerulonephritis). Homogeneous eosinophilic material which filled the glomerular capillary lumina was found in five horses. Ultrastructurally, this material primarily consisted of electron-dense deposits with a fibrillar pattern in five horses and in one horse, rhomboid crystalline deposits which resembled deposits seen in human cryoglobulinemia. The association of mesangioprolif...
Controlled tests of activity of ivermectin against natural infections of migratory large strongyles and other internal parasites of equids.
American journal of veterinary research    November 1, 1984   Volume 45, Issue 11 2267-2271 
Drudge JH, Lyons ET, Tolliver SC.Four controlled tests (experiments A, B, C, and D) were conducted in naturally infected yearling equids to evaluate activity of ivermectin (0.2 mg/kg IM) against migrating Strongylus vulgaris and S edentatus in mesenteric arteries and ventral abdominal wall, respectively. Data were also obtained on activity against other internal parasites of the gastrointestinal tract and eyeworms. The type and number of equids in the experiments were as follows: experiment A-3 ponies, 2 treated and 1 non-treated; experiment B-4 mixed-bred horses, 2 treated and 2 nontreated; experiment C-5 mixed-bred horses, ...
Eosinophilic myeloproliferative disorder in a horse.
Journal of the American Veterinary Medical Association    November 1, 1984   Volume 185, Issue 9 993-996 
Morris DD, Bloom JC, Roby KA, Woods K, Tablin F.An eosinophilic myeloproliferative disorder resulted in edema and hemorrhagic diathesis in a 10-month-old Standardbred colt. Laboratory abnormalities included severe thrombocytopenia, anemia, mild hypoproteinemia, and marked eosinophilia. Circulating eosinophils were immature or atypical with variation in granule size, disproportionate nuclear to cytoplasmic maturation, and abnormal nuclear size and shape. Bone marrow aspirate had mainly atypical eosinophil precursors, few erythroid precursors, and no megakaryocytes. A blood transfusion and dexamethasone therapy resulted in some improvement; h...
[Keratinizing squamous cell carcinoma in the stomach of a horse].
DTW. Deutsche tierarztliche Wochenschrift    October 8, 1984   Volume 91, Issue 10 374-375 
Schoon A, Richter J, Deegen E.No abstract available
Evaluation of ivermectin against later fourth-stage Strongylus vulgaris in ponies at two and five weeks after treatment.
Canadian journal of comparative medicine : Revue canadienne de medecine comparee    October 1, 1984   Volume 48, Issue 4 343-348 
Slocombe JO, McCraw BM.The efficacy of ivermectin against later fourth-stage Strongylus vulgaris larvae was studied in pony foals at 14 and 35 days after treatment. These foals had been reared parasite-free, inoculated with 500 infective larvae and 56 days later given either ivermectin at 200 micrograms/kg or a placebo intramuscularly. At necropsy, foals were examined for lesions and larvae grossly and histologically. Ivermectin was found to be highly effective (98.6%) against later fourth-stage larvae in five foals which were examined at 35 days after treatment, but not in five others examined at 14 days (72.5%). I...
Chondrosarcoma in the radius of a horse.
Journal of the American Veterinary Medical Association    September 1, 1984   Volume 185, Issue 5 534-537 
Bertone AL, Powers BE, Turner AS.An aged Thoroughbred stallion was examined because of progressive lameness, carpal swelling, and weight loss. Radiography revealed a destructive lesion in the caudomedial, distal portion of the radius. Chondrosarcoma was diagnosed by tumor-core biopsy. Gross and histologic evaluation of the neoplasm after necropsy revealed a locally invasive chondrosarcoma at the distal end of the radius that infiltrated the radiocarpal joint capsule and invaded the carpal bones. The malignant nature of this tumor was evident by its invasiveness and histologic features of cell pleomorphism and presence of mito...
Dirofilariasis with arteriosclerosis in a horse.
Journal of the American Veterinary Medical Association    September 1, 1984   Volume 185, Issue 5 532-533 
Thurman JD, Johnson BJ, Lichtenfels JR.Arteriosclerosis caused by Dirofilaria immitis adult parasites was diagnosed in a 20-month-old Quarter horse stallion that died from cantharidin toxicosis. Microscopically, the pulmonary vascular changes were typical of those described as "proliferative endarteritis" in D immitis-infected dogs.
Observations on structure and function of the equine mitral valve.
Equine veterinary journal    September 1, 1984   Volume 16, Issue 5 457-460 doi: 10.1111/j.2042-3306.1984.tb01979.x
Miller PJ, Holmes JR.The anatomy of the equine mitral valve and certain variations observed in 60 adult horses are described. The functional role of this valve, sited between the left atrium and the high pressure-generating left ventricle, is discussed in relation to its anatomical structure. A method of examining the left side of the heart post mortem is described.
Complications associated with the use of the cuffless endotracheal tube in the horse.
Journal of the American Veterinary Medical Association    September 1, 1984   Volume 185, Issue 5 541-542 
Trim CM.Complications following the use of the cuffless large animal endotracheal tube during general anesthesia in 2 horses are reported. One horse developed laryngeal edema during recovery. The edema was treated successfully with dexamethasone, but severe laryngeal trauma was confirmed 24 hours later at necropsy. The second horse had a swollen tongue and had difficulty eating for 3 days after anesthesia. The condition resolved without treatment. this report is a reminder of the potential damage which can occur from endotracheal intubation.
Hypoplastic left ventricular syndrome in a foal.
Journal of the American Veterinary Medical Association    September 1, 1984   Volume 185, Issue 5 542-543 
Musselman EE, LoGuidice RJ.A necropsy diagnosis of hypoplastic left ventricular syndrome was made in a day-old foal. The cardiac abnormalities included mitral and aortic valve atresia, patent ductus arteriosus, and a secundum atrial septal defect. The left ventricle was hypoplastic and nonfunctional. The brief survival of the foal was a consequence of left-to-right shunting through the atrial septal defect and right-to-left shunting through the patent ductus. The information is presented to demonstrate the existence of the syndrome as a congenital defect in the horse and to clarify the necropsy findings for the practiti...
Granulomatous colitis associated with small strongyle larvae in a horse.
Journal of the American Veterinary Medical Association    September 1, 1984   Volume 185, Issue 5 553-554 
Jasko DJ, Roth L.Horses presented with chronic weight loss are difficult to manage clinically. A diagnosis of granulomatous colitis due to mucosal stages of cyathostomes (small strongyles) should be considered in those cases exhibiting weight loss, intermittent diarrhea, hypoalbuminemia, increased serum globulins, and low fecal egg counts. Treatment can be attempted with larva-cidal doses of fenbendazole or ivermectin. Clinical and necropsy findings in one such case are presented.
[Anatomopathological study of the liver in horses with fascioliasis].
Boletin chileno de parasitologia    July 1, 1984   Volume 39, Issue 3-4 43-46 
Luengo J, Arata N, Luengo M, Araya N.No abstract available
Monocytic leukemia in a horse.
Veterinary pathology    July 1, 1984   Volume 21, Issue 4 394-398 doi: 10.1177/030098588402100405
Burkhardt E, von Saldern F, Huskamp B.On clinical examination, a six-year-old Hassian gray gelding with a history of impaired performance, slight cough, colic, and edema of the ventral abdomen, prepuce and the legs had reduced skin turgor, pale mucous membranes, forced costoabdominal breathing, reduced venous return, enlarged lymph nodes, and splenomegaly. Hematologic findings revealed anemia, leukocytosis and a high percentage of monocytoid leukemic cells. Generalized lymphadenopathy, splenomegaly, ascites, hydrothorax, and a diffusely thickened gut wall were found at necropsy. Massive infiltration with monocytoid leukemic cells ...
The prevalence and intensity of internal parasites of horses in the U.S.A.
Veterinary parasitology    July 1, 1984   Volume 15, Issue 1 75-83 doi: 10.1016/0304-4017(84)90112-2
Reinemeyer CR, Smith SA, Gabel AA, Herd RP.Fifty-five adult horses were necropsied over a 15-month period, and their worm burdens counted and speciated. Twenty-one species of Cyathostominae were recovered. Ten species: Cyathostomum catinatum, Cylicocyclus nassatus, Cylicostephanus longibursatus, Cyathostomum coronatum, Cylicostephanus goldi, C. calicatus, C. minutus, Cylicocyclus leptostomus, C. insigne and Cyathostomum pateratum, comprised 98.9% of the total cyathostome burdens. These same 10 species also demonstrated high prevalences in 4 previous surveys. Eight of these 10 species have been shown to be resistant to benzimidazole ant...
Guttural pouch hemorrhage associated with lesions of the maxillary artery in two horses.
The Canadian veterinary journal = La revue veterinaire canadienne    June 1, 1984   Volume 25, Issue 6 239-242 
Smith KM, Barber SM.A two year old Thoroughbred gelding, presented with guttural pouch hemorrhage, had the internal and external carotid arteries ligated. Guttural pouch mycosis was detected on endoscopic examination. After one month of topical antifungal therapy, the horse was returned and euthanized because of recurrent epistaxis. A bacterial infection of the guttural pouch with associated ulceration and hemorrhage from the maxillary artery was found at necropsy.A two year old grade gelding had ulceration and hemorrhage from the external carotid artery. Utilizing balloon-tipped catheters and arterial ligation, ...
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