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Topic:Ophthalmology

Ophthalmology in horses encompasses the study and treatment of eye disorders and diseases affecting equine species. Equine ophthalmic conditions can range from conjunctivitis and corneal ulcers to more complex issues such as uveitis and cataracts. These conditions can impact a horse's vision and overall well-being. Diagnostic techniques in equine ophthalmology include visual examinations, fluorescein staining, and advanced imaging methods like ultrasonography. Treatment approaches vary depending on the specific condition and may involve medication, surgical intervention, or supportive care. This page compiles peer-reviewed research studies and scholarly articles that explore the anatomy, pathology, diagnostics, and treatment modalities related to equine ophthalmology.
Ocular mastocytosis in a horse.
Australian veterinary journal    January 1, 1989   Volume 66, Issue 1 32 doi: 10.1111/j.1751-0813.1989.tb09712.x
Hum S, Bowers JR.No abstract available
Clinical uses of hyaluronan.
Ciba Foundation symposium    January 1, 1989   Volume 143 265-285 doi: 10.1002/9780470513774.ch16
Balazs EA, Denlinger JL.The availability of elastoviscous solutions of highly purified hyaluronan has created two new therapeutic methods in human and veterinary medicine: viscosurgery and viscosupplementation. Viscosurgical tools and implants are widely used in ophthalmology and have been suggested for use in otology. Visco-supplementation of joint fluid using elastoviscous hyaluronan solutions is widely used in the treatment of equine traumatic arthritis. It was also suggested for use in idiopathic osteoarthritis in humans, but this application has not received wide acceptance. Cross-linked forms of hyaluronan have...
[Surgical removal of a cyst from the iris of a horse].
Schweizer Archiv fur Tierheilkunde    December 1, 1988   Volume 130, Issue 12 673-680 
Gywat L, Keller M, Gutzwiller A, Daicker B, Brückner R.No abstract available
Aqueous drainage paths in the equine eye: scanning electron microscopy of corrosion cast.
Journal of morphology    October 1, 1988   Volume 198, Issue 1 33-42 doi: 10.1002/jmor.1051980105
Smith P, Samuelson D, Brooks D.The anterior vasculature of the pony eye was examined by the corrosion cast method. The anterior segment of the pony eye has a vascular pattern which is similar but distinct from that of other mammalian species. Large iridal veins collateralized directly with the anterior vortex venous system. The intrascleral plexus was present but formed a fine, radially oriented, extensive network. This contrasted to the circumferential larger-diameter intrascleral plexus noted in dogs and the canal of Schlemm present in primates. The intrascleral plexus only drained posteriorly in the pony as compared to t...
Adherence of streptococcal isolates from cattle and horses to their respective host epithelial cells.
American journal of veterinary research    September 1, 1988   Volume 49, Issue 9 1485-1488 
Valentin-Weigand P, Chhatwal GS, Blobel H.Adherence of Streptococcus dysgalactiae isolates from cattle and S equi isolates from horses to their respective host epithelial cells was compared with the adherence of S pyogenes to human epithelial cells. The adherence was quantitatively determined by use of fluorescein-labeled streptococci. All 3 streptococcal species adhered selectively to their respective host cells. The mechanism of adherence was evaluated by binding studies with adhesive plasma protein, fibronectin. Although all 3 streptococcal species bound fibronectin, S dysgalactiae and S equi interacted preferentially with a 210-ki...
Intraocular silicone prosthesis in a horse.
Journal of the American Veterinary Medical Association    August 1, 1988   Volume 193, Issue 3 343-345 
Meek LA.A 40-mm intraocular silicone prosthesis was placed in a horse's globe to control glaucoma. The glaucoma was suspected to be associated with a lens subluxation, but primary glaucoma could not be ruled out. Medical treatment and cyclocryotherapy had been attempted, but failed to decrease the intraocular pressure to a normal value. The prosthesis was placed, via a dorsal scleral incision, after removal of the intraocular contents. The size of the prosthesis was estimated from measurements of the horse's normal left globe and an enucleated, age-matched globe. Silicone prostheses offer a cosmetic a...
Aberrant cilia as an aetiology for recurrent corneal ulcers: a case report.
Equine veterinary journal    March 1, 1988   Volume 20, Issue 2 145-146 doi: 10.1111/j.2042-3306.1988.tb01482.x
Miller WW.No abstract available
Retrobulbar hydatid cyst in the horse.
Equine veterinary journal    March 1, 1988   Volume 20, Issue 2 136-138 doi: 10.1111/j.2042-3306.1988.tb01478.x
Barnett KC, Cottrell BD, Rest JR.No abstract available
Serologic correlation of suspected Leptospira interrogans serovar pomona-induced uveitis in a group of horses.
Journal of the American Veterinary Medical Association    December 15, 1987   Volume 191, Issue 12 1576-1578 
Sillerud CL, Bey RF, Ball M, Bistner SI.After the observation of 2 horses with uveitis on a horse farm in the Minnesota River valley, 100 horses from this geographic area were given ophthalmologic examinations and were evaluated serologically for leptospirosis. A statistically significant (P less than 0.001) association was observed between the finding of antibodies against Leptospira interrogans serovar pomona and uveitis.
Equine ocular pathology ascribed to Onchocerca cervicalis infection: a re-examination. Moran CT, James ER.Eyes from 292 old (15-20 years) horses originating in the eastern, southeastern and midwestern United States were examined for the presence of Onchocerca cervicalis microfilariae (mf) and concurrently for anterior and posterior segment ocular pathological changes. One-hundred-fifty-three animals (52.4%) were positive for dermal mf (range 0.03-5,364/mg). Of these, 60 animals had anterior segment changes. An additional 58 animals with pathological changes had no dermal mf. Mf were recovered from the ocular tissues of 18% of animals (range 0.07-29/mg). All animals with ocular mf were positive for...
Retinal astrocytes: their restriction to vascularized parts of the mammalian retina.
Neuroscience letters    July 9, 1987   Volume 78, Issue 1 29-34 doi: 10.1016/0304-3940(87)90556-8
Schnitzer J.The distribution of astrocytes has been studied in whole-mounted horse and monkey retinae by the immunocytochemical localization of glial fibrillary acidic protein (GFAP). In the horse, astrocytes were found to be restricted to a narrow zone close to the optic nerve head. This is also the only region of the horse retina that is vascularized. In the monkey, astrocytes were found ubiquitously in the nerve fiber layer of the retina, apart from the avascular fovea centralis which lacked astrocytes. These observations strongly suggest that retinal astrocytes co-occur with blood vessels, a feature w...
Bilateral melanoma of the iris in a horse.
Equine veterinary journal    July 1, 1987   Volume 19, Issue 4 358-360 doi: 10.1111/j.2042-3306.1987.tb01434.x
Matthews AG, Barry DR.No abstract available
Equine periodic ophthalmia: a continuing aetiological riddle.
Equine veterinary journal    March 1, 1987   Volume 19, Issue 2 90-91 doi: 10.1111/j.2042-3306.1987.tb02594.x
Barnett KC.No abstract available
Immunodiagnosis of leptospiral uveitis in two horses.
Equine veterinary journal    March 1, 1987   Volume 19, Issue 2 155-157 doi: 10.1111/j.2042-3306.1987.tb02615.x
Davidson MG, Nasisse MP, Roberts SM.No abstract available
Healing of experimentally induced corneal ulcers in horses.
American journal of veterinary research    March 1, 1987   Volume 48, Issue 3 427-430 
Neaderland MH, Riis RC, Rebhun WC, Erb HN.Corneal ulcers to the depth of the anterior third of the stroma were created surgically in both eyes of 10 ponies. One eye in each pony was treated topically with chloramphenicol and 1% atropine ophthalmic ointments 3 times per day; the contralateral eye was not treated topically. All ponies were given phenylbutazone orally for relief of ocular pain. Fluorescein-stained ulcers were measured once a day. The median healing time of the treated eyes (11 days) and the median healing time of the nontreated eyes (13.5 days) were found not to be significantly different. Clinically, however, more sever...
Serological study of leptospiral infections and endogenous uveitis among horses and ponies in the United Kingdom.
Equine veterinary journal    March 1, 1987   Volume 19, Issue 2 125-128 doi: 10.1111/j.2042-3306.1987.tb02605.x
Matthews AG, Waitkins SA, Palmer MF.The prevalence of antibody titres to a range of 20 leptospira antigens in the serum of horses and ponies with no ophthalmic abnormalities and with ophthalmoscopic evidence of endogenous uveal inflammatory disease was determined using a microscopic agglutination technique. Titres against leptospira antigens were observed in 13 out of 138 (9.1 per cent) animals with no ophthalmic abnormalities, and in three out of 27 (11.1 per cent) animals with anterior uveitis. Serovar sejroe was common to all seropositive animals with anterior uveitis. The results show that leptospira infection is not a major...
Effect of topical phenylephrine on the equine pupil.
American journal of veterinary research    February 1, 1987   Volume 48, Issue 2 320-322 
Hacker DV, Buyukmihci NC, Franti CE, Bellhorn RW.The mydriatic effect of 10% phenylephrine was evaluated in 9 horses. Base-line pupillary size in mesopic conditions and during light stimulation was ascertained before application of pharmacologic agents. In study 1, 10% phenylephrine was applied to each eye (n = 5 horses). After 15 minutes, the pupillary size was determined in both lighting conditions. Phenylephrine was again applied to each eye, and after an additional 15 minutes, the pupillary size was determined. In study 2, 1% tropicamide was applied to each eye (n = 4 horses), and after 30 minutes, the pupillary size was determined in bo...
Tears and aqueous humor from horses inoculated with Leptospira contain antibodies which bind to cornea.
Veterinary immunology and immunopathology    February 1, 1987   Volume 14, Issue 2 181-185 doi: 10.1016/0165-2427(87)90052-3
Parma AE, Fernández AS, Santisteban CG, Bowden RA, Cerone SI.An antigenic relationship between Leptospira interrogans and equine cornea was previously described by us. An enzyme-linked immunosorbent assay was employed in the present work to investigate the existence of anti-leptospira and anti-cornea antibodies in tears, aqueous humor and serum from horses inoculated i.m. with those antigens. Ten days after a booster by the same route, antibodies that bind to microtiter plates, coated with an homogenate of either equine cornea or leptospira, were detected in those fluids and in the sera. At the same time, the corneas of the horses began to develop a dif...
The optics of comparative ophthalmoscopy.
Vision research    January 1, 1987   Volume 27, Issue 4 599-607 doi: 10.1016/0042-6989(87)90045-9
Murphy CJ, Howland HC.One factor peculiar to the practice of comparative ophthalmoscopy is the very large variation in ocular size of the animals examined, a factor which is ignored in current textbook treatments of the subject. We have computed values of lateral magnification, axial magnification, angular field of view and linear field of view for 19 species of terrestrial vertebrates. The dimensional value of a 1 diopter change in direct ophthalmoscopic focus was also determined. The anterior focal length of the eye in air and the vitreal refractive index were the intrinsic optical parameters of the animal's eye ...
Ocular angiosarcoma in four horses.
Journal of the American Veterinary Medical Association    July 15, 1986   Volume 189, Issue 2 200-203 
Hacker DV, Moore PF, Buyukmihci NC.In 4 horses with ocular angiosarcomas, the common characteristics were that all horses were aged, and the neoplasms developed initially on conjunctival surfaces, grew slowly, and metastasized despite excision and radiation treatment. Histopathologically, the neoplasms were of 2 types: a capillary pattern of scant stroma and endothelial-lined vascular channels, and a solid pattern composed of sheets of pleomorphic cells with hyperchromatic nuclei and poorly defined cytoplasmic borders. Definitive diagnosis was made by use of factor VIII:RAg, which stained the tissues intensely.
Albumin and immunoglobulins G, A and M in aqueous humour from clinically normal equine eyes.
Equine veterinary journal    March 1, 1986   Volume 18, Issue 2 117-120 doi: 10.1111/j.2042-3306.1986.tb03562.x
Matthews AG, Poulter T.The levels of albumin, immunoglobulin G (including IgG [T]), IgA and IgM in the serum and aqueous humour of 47 horses and ponies with no ophthalmic abnormalities were determined by single radial immunodiffusion. There was a linear relationship between serum and aqueous albumin levels. No relationship of serum and aqueous IgG levels was observed. IgA was detected in only one aqueous sample. IgM was not detected in aqueous humour from any eye in this study. The factors which may influence albumin and immunoglobulin levels in normal aqueous humour are discussed.
Effect of xylazine and ketamine on intraocular pressure in horses.
The Veterinary record    October 26, 1985   Volume 117, Issue 17 442-443 doi: 10.1136/vr.117.17.442
Trim CM, Colbern GT, Martin CL.Intraocular pressure was measured with a MacKay-Marg tonometer in eight horses following auriculopalpebral nerve block and topical application of lignocaine. Measurements were recorded before and after xylazine, 1.1 mg/kg intravenously, every two minutes for 16 minutes after administration of ketamine, 2.2 mg/kg intravenously, and after recovery from anaesthesia. Before xylazine, intraocular pressure was 17.1 +/- 3.9 and 18.4 +/- 2.2 mm Hg in the left and right eyes, respectively. Intraocular pressure tended to decrease after administration of xylazine and ketamine, with a significant decrease...
Ocular disease in the horse.
In practice    September 1, 1985   Volume 7, Issue 5 153-157 doi: 10.1136/inpract.7.5.153
Bedford P.No abstract available
Inherited nuclear cataracts in the Morgan horse.
The Journal of heredity    September 1, 1985   Volume 76, Issue 5 371-372 
Beech J, Irby N.Congenital cataracts affecting the fetal and embryonal lens nucleus were found in 12 Morgan horses. Ten of the 12 affected animals were sired by the same stallion and the condition also affected his female half sibling. Although females were almost three times more likely to be affected than males (9 vs 3), the difference was not significant. The ratio of 11 normal to 10 affected offspring by the affected stallion is compatible with an autosomal dominant mode of inheritance.
Ulcerative keratitis associated with Salmonella arizonae infection in a horse.
Journal of the American Veterinary Medical Association    June 1, 1985   Volume 186, Issue 11 1219-1220 
Adamson PJ, Jang SS.Salmonella arizonae 61:1,5, was isolated in pure culture from the eye of a horse with unilateral ulcerative keratitis. The eye responded well to treatment with atropine sulfate and polymyxin B-bacitracin-neomycin ophthalmic ointments. In swab specimens taken after the lesion had healed, Salmonella was not found to be a constituent of the bacterial flora of the horse's eyes.
Neonatal ophthalmology.
The Veterinary clinics of North America. Equine practice    April 1, 1985   Volume 1, Issue 1 235-259 doi: 10.1016/s0749-0739(17)30779-4
Latimer CA, Wyman M.This discussion of normal and abnormal findings on routine ophthalmic examination of the foal should prove useful to the equine practitioner who must provide counsel to the concerned owner and/or breeder. Early diagnosis and treatment of ocular abnormalities improve the prognosis for continued function and aid determination of the significance of lesions observed in later life.
Laboratory evaluation of aqueous humor in the healthy dog, cat, horse, and cow.
American journal of veterinary research    March 1, 1985   Volume 46, Issue 3 657-659 
Hazel SJ, Thrall MA, Severin GA, Lauerman LH, Lavach JD.Using routinely available clinical laboratory methods, aqueous humor samples were evaluated from 12 healthy dogs, 15 healthy cats, 7 healthy horses, and 6 healthy cows. Aqueous humor was almost acellular; cells that were present had degenerated beyond recognition. Protein concentration was low; only albumin was detectable on electrophoresis. Creatine phosphokinase and lactate dehydrogenase isoenzymes were not detected. Artifacts induced by sampling were insignificant compared with alterations in aqueous humor composition that occur with ocular diseases.
Congenital aniridia in a pony.
Journal of the American Veterinary Medical Association    February 1, 1985   Volume 186, Issue 3 281-283 
Irby NL, Aguirre GD.No abstract available
Evaluation of fluorescein dye as an indicator of small intestinal viability in the horse.
Journal of the American Veterinary Medical Association    February 1, 1985   Volume 186, Issue 3 257-261 
Sullins KE, Stashak TS, Mero KN.In 6 horses, 2 types of ischemic lesions were created in small intestinal segments by selective ligation of vessels and intestinal wall for 1, 2, or 3 hours. After confirming the ischemia by IV injection of sodium fluorescein, the ligatures were released. Five minutes later, the fluorescent patterns were documented photographically. Observed patterns ranged from normal (identical to that observed in unaffected bowel) to a patchy distribution of non-fluorescence (indicating incomplete perfusion). None of the experimental segments was normal when reevaluated 1 month later. The typical appearance...
Congenital ocular disease in the foal.
The Veterinary clinics of North America. Large animal practice    November 1, 1984   Volume 6, Issue 3 519-537 doi: 10.1016/s0196-9846(17)30008-3
Munroe GA, Barnett KC.No abstract available
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