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Topic:Peritonitis

Peritonitis in horses refers to inflammation of the peritoneum, the thin membrane lining the abdominal cavity and covering the abdominal organs. This condition can result from various causes, including bacterial infections, gastrointestinal perforations, or abdominal trauma. Clinical signs in horses may include abdominal pain, fever, anorexia, and depression. Diagnosis typically involves clinical examination, blood tests, and abdominal fluid analysis. Treatment strategies often include antimicrobial therapy, anti-inflammatory medications, and supportive care. This page aggregates peer-reviewed research studies and scholarly articles that explore the etiology, pathophysiology, diagnostic methods, and treatment options for peritonitis in equine patients.
Omental fibrosarcoma in a horse.
Journal of the American Veterinary Medical Association    August 1, 1987   Volume 191, Issue 3 335-336 
Harvey KA, Morris DD, Saik JE, Donawick WJ.A 13-year-old Thoroughbred mare had a 2-week history of weight loss and intermittent fever. Examination of abdominal and pleural fluid revealed peritonitis and pleuritis. Ultrasonography of the ventral abdominal midline revealed an intra-abdominal mass. Exploratory celiotomy was performed, but the mass was not surgically excisable. The mare was euthanatized and necropsied. Histologically, the mass was determined to be a fibrosarcoma of omental origin.
Elective inversion of the distal ileal stump into the caecum of the horse.
Equine veterinary journal    May 1, 1987   Volume 19, Issue 3 223-225 doi: 10.1111/j.2042-3306.1987.tb01386.x
Vasey JR, Julian RJ.The distal 30 to 40 cm of the ileum cannot be exteriorized through a midline laparotomy incision because of its close anatomical association with the base of the caecum. A method was developed to deal with those cases where this segment of small intestine was involved in an avascular, necrotic process and therefore required resection. The technique involves inverting the distal stump of ileum into the lumen of the caecum and then performing a routine ileocaecal or jejunocaecal anastomosis. This avoids the risk of peritonitis if a Parker-Kerr oversew of the necrotic ileal stump should dehisce. ...
Suppurative splenitis and peritonitis in a horse after gastric ulceration caused by larvae of Gasterophilus intestinalis.
Australian veterinary journal    May 1, 1987   Volume 64, Issue 5 155-158 doi: 10.1111/j.1751-0813.1987.tb09669.x
Dart AJ, Hutchins DR, Begg AP.A 12-year-old Thoroughbred mare, with a history of anorexia, dramatic weight loss, fluctuating pyrexia and intermittent diarrhoea after an episode of colic, was presented for examination with depression, emaciation and ataxia. Thoracic and abdominal paracenteses yielded copious quantities of inflammatory exudate. Palpation per rectum revealed an enlarged spleen. The primary alterations in haematology included a severe leucocytosis with a left shift, and a hyperproteinaemia characterised by hypoalbuminaemia and hypergammaglobulinaemia. Post-mortem examination revealed a low grade pleurisy and p...
Repeat sternotomy after reconstruction of the pericardial sac with glutaraldehyde-preserved equine pericardium.
The Journal of thoracic and cardiovascular surgery    April 1, 1987   Volume 93, Issue 4 616-619 
von Segesser L, Jornod N, Faidutti B.The risk of repeat sternotomy is higher than that of the initial sternotomy, especially if the pericardial sac was left open at the first intervention. In 200 consecutive patients with a pericardial defect after open heart operations, the pericardium was closed with a glutaraldehyde-preserved equine pericardial patch. Precardiac adhesions at reoperation were assessed in four groups of patients on a scale of 6, ranging from 0 (no adhesions) to 5 (calcified or ossified adhesions). Group I comprised 13 patients in whom the pericardium was left open at the first operation and an equine pericardial...
Strangulated umbilical hernias in horses: 13 cases (1974-1985).
Journal of the American Veterinary Medical Association    March 15, 1987   Volume 190, Issue 6 692-694 
Markel MD, Pascoe JR, Sams AE.The medical records of 13 horses with strangulated umbilical hernias were reviewed. Typical history included increased swelling, warmth, and firmness of the hernial sac. Enterocutaneous fistulas had developed in 2 horses. Four horses had signs of abdominal pain. Surgery was performed on all horses, and the hernia was reduced by an open reduction technique. Incarcerated tissue included omentum (1 horse), jejunum (5), ileum (4), cecum (1), and ventral colon (2). All horses survived and were discharged from the hospital. Follow-up information on 9 horses (5 to 52 months after discharge) revealed ...
Hemorrhagic fibrinonecrotic duodenitis-proximal jejunitis in horses: 20 cases (1977-1984).
Journal of the American Veterinary Medical Association    February 1, 1987   Volume 190, Issue 3 311-315 
White NA, Tyler DE, Blackwell RB, Allen D.Records of 20 horses with small intestinal disease causing acute colic and affecting the proximal portion of the small intestine were examined retrospectively. The disease was characterized by severe to moderate pain, which was replaced by depression, fever, gastric reflux, slight distention of the affected small intestine, leukocytosis, and high concentrations of total protein in the peritoneal fluid. Grossly, the affected intestines were hemorrhagic and had yellow discoloration. Histopathologic findings included submucosal edema, neutrophilic infiltration of the submucosal and laminal propri...
Gastric rupture in horses: a review of 54 cases.
Equine veterinary journal    July 1, 1986   Volume 18, Issue 4 288-293 doi: 10.1111/j.2042-3306.1986.tb03631.x
Todhunter RJ, Erb HN, Roth L.The historical, clinical, laboratory, surgical and necropsy findings in 54 cases of gastric rupture in horses are described. Eleven per cent of the deaths of horses undergoing exploratory coeliotomy for colic during the period of the study were a result of gastric rupture. Comparison with all horses which had exploratory coeliotomies for colic over an eight year period did not show that horses with gastric rupture were different from these reference horses regarding age, breed or season. There were fewer stallions than expected in the gastric rupture group. Horses with histories of both acute ...
Gastroduodenal ulceration in foals.
Equine veterinary journal    July 1, 1986   Volume 18, Issue 4 307-312 doi: 10.1111/j.2042-3306.1986.tb03638.x
Becht JL, Byars TD.Gastroduodenal ulceration is becoming recognised as an important disease in foals during the first few months of life. Aetiopathogenesis is presumed to be similar to peptic disease in humans associated with back diffusion of hydrogen ions into the mucosa. Many factors have been incriminated as predisposing foals to ulceration but few have been proven. To date, use of non-steroidal anti-inflammatory agents has been the only documented cause of gastroduodenal ulceration in foals. The clustering of affected foals on certain farms suggests an infectious aetiology but attempts to identify a causati...
Diseases of the abdomen.
The Veterinary clinics of North America. Equine practice    April 1, 1986   Volume 2, Issue 1 67-88 doi: 10.1016/s0749-0739(17)30733-2
Rantanen NW.Because the abdomen of the adult horse is too thick to obtain good-quality radiographs, diagnostic ultrasound is a particularly valuable imaging modality in the diagnosis of abdominal disease. The size, shape, position, and texture of the liver, spleen, kidneys, urinary bladder, gravid uterus, and gut wall can be determined by scanning the abdominal surface. The presence or absence of abdominal fluid can be determined efficiently. Gut motility as well as ileus secondary to peritonitis or obstruction can be assessed. Suspected adhesions of the bowel can often be documented, and primary or secon...
Uterine rupture as a postpartum complication in two mares.
Journal of the American Veterinary Medical Association    December 15, 1985   Volume 187, Issue 12 1377-1379 
Brooks DE, McCoy DJ, Martin GS.Uterine rupture was diagnosed in 2 postpartum mares with hemorrhagic vaginal discharge. Both mares had abdominal pain, as evidenced by pawing, kicking at the abdomen, or attempting to roll. Peritoneal fluid analysis was useful in establishing a diagnosis. One mare had many RBC in the peritoneal fluid and was anemic; this mare was managed medically with oxytocin, antibiotics, and blood transfusion. The mare was able to raise her foal to weaning age. The second mare had many RBC, degenerate neutrophils, and intracellular and extracellular bacteria in peritoneal fluid. Surgical repair of the uter...
Perirectal abscesses in six horses.
Journal of the American Veterinary Medical Association    September 1, 1985   Volume 187, Issue 5 499-500 
Sanders-Shamis M.Perirectal abscesses were diagnosed retrospectively in 6 horses treated for colic. The abscesses caused colic in the horses by producing an extraluminal obstruction that led to fecal impaction. The abscesses were diagnosed by rectal palpation and aspiration of exudate from the masses and were drained surgically. In horses in which the abscess involved abdominal organs, peritonitis developed.
Cecal perforation in the horse.
Journal of the American Veterinary Medical Association    August 1, 1985   Volume 187, Issue 3 249-253 
Ross MW, Martin BB, Donawick WJ.The case records of 23 horses with cecal perforation (CP) were reviewed. The horses averaged 4.5 years of age (6 weeks to 13 years) and included 9 intact males, 12 mares, and 2 geldings. Twelve of the horses were Standardbreds, 9 were Thoroughbreds, and 1 each, a Belgian and Morgan. The horses were allotted to 2 groups: group I-13 hospitalized horses in which CP occurred unexpectedly, and group II-10 horses with CP at the time of admission. The horses characteristically had been sick or affected with disease unrelated to the cecum. Sixteen horses had been given nonsteroidal anti-inflammatory d...
Comparison of three suture techniques for anastomosis of the small intestine in the horse.
American journal of veterinary research    June 1, 1985   Volume 46, Issue 6 1282-1286 
Dean PW, Robertson JT.Seven horses were used to compare the Gambee, the crushing, and a 2-layer inverting suture pattern composed of a simple continuous layer in the mucosa oversewn with a continuous Lembert pattern in the seromuscular layer. Horses were evaluated at 30 days for adhesion formation, lumen diameter, and quality of healing at the anastomotic sites. One horse was euthanatized 9 days after surgery after 24 hours of ileus and colic; necropsy revealed septic peritonitis and widespread adhesions. One horse had no adhesions. The remaining horses had adhesions associated with 50% of the Gambee and 50% of the...
Exsanguination due to gastric ulceration in a foal.
Journal of the American Veterinary Medical Association    February 1, 1985   Volume 186, Issue 3 280-281 
Traub-Dagartz J, Bayly W, Riggs M, Thomas N, Pankowski R.An Arabian foal with a congenital heart disease died due to hemorrhage secondary to a large gastric ulcer. Previously, death of foals with gastric ulcers has been due to diffuse peritonitis resulting from gastric ulcer perforation. The foal in this case report died due to hemorrhage secondary to a large gastric ulcer.
Therapeutic strategies involving antimicrobial treatment of large animals with peritonitis.
Journal of the American Veterinary Medical Association    November 15, 1984   Volume 185, Issue 10 1222-1225 
Kunesh JP.No abstract available
Vaginal perforation after coitus in three mares.
Journal of the American Veterinary Medical Association    September 1, 1984   Volume 185, Issue 5 533-534 
Held JP, Blackford JT.Three cases of vaginal perforation after coitus are discussed. The most consistent clinical sign is a small amount of blood escaping from the vulvar lips immediately after breeding. Secondary infection and posttraumatic swelling may cause abdominal pain due to rectal impaction. Treatment with high levels of an appropriate antibiotic is important to reduce the risk of a severe infectious peritonitis. The use of artificial insemination or a breeding roll to prevent full intromission is recommended.
Ulcerative duodenitis in foals.
Veterinary pathology    November 1, 1983   Volume 20, Issue 6 653-661 doi: 10.1177/030098588302000601
Acland HM, Gunson DE, Gillette DM.Seven foals aged 18 days to 3 1/2 months had either single or multiple full-circumference segments or long antimesenteric bands of necrotizing duodenitis, sharply delineated from adjacent viable duodenum. Perforation of the necrotic wall had occurred in all foals, leading to acute fibrinous peritonitis. On the mucosal surface severe diffuse, acute inflammation and ulceration involved the anterior half of the duodenum. Two further foals, aged 28 and 30 days, had lesions that are believed to be a chronic form of this disease. Both foals had a thickened duodenal wall, with large areas of mucosa r...
Cecal perforation and peritonitis associated with Anoplocephala perfoliata infection in three horses.
Journal of the American Veterinary Medical Association    October 1, 1983   Volume 183, Issue 7 804-806 
Beroza GA, Barclay WP, Phillips TN, Foerner JJ, Donawick WJ.No abstract available
Renal papillary necrosis in horses after phenylbutazone and water deprivation.
Veterinary pathology    September 1, 1983   Volume 20, Issue 5 603-610 doi: 10.1177/030098588302000512
Gunson DE, Soma LR.Acute renal papillary necrosis occurred in five horses given normal therapeutic doses of phenylbutazone and deprived of water for 36 to 48 hours prior to euthanasia. Five horses given phenylbutazone alone and four horses subjected to water deprivation alone did not develop papillary necrosis. Urinalyses were normal prior to water deprivation, and also after water deprivation in the horses that did not receive phenylbutazone, but the water-deprived, phenylbutazone-treated horses had many red blood cells, transitional epithelial cells, and large numbers of oxalate crystals in their urine. Ulcera...
Review of 30 cases of peritonitis in the horse.
Equine veterinary journal    January 1, 1983   Volume 15, Issue 1 25-30 doi: 10.1111/j.2042-3306.1983.tb01693.x
Dyson S.Thirty cases of peritonitis, in which the diagnosis was based on a peritoneal fluid white blood cell count in excess of 10 x 10(9)/litre, are described. Colic, ileus, pyrexia, weight loss and diarrhoea were common presenting signs. Treatments included intravenous fluids, anti-inflammatory analgesics, broad spectrum antibiotics and anthelmintics. Duration of treatment was determined by the clinical condition of the horse and sequential analyses of the peritoneal fluid and the haemogram. In the majority of cases the primary cause of peritonitis was not accurately determined, but 21 horses (70 pe...
Noniatrogenic rectal tears in three horses.
Journal of the American Veterinary Medical Association    April 1, 1982   Volume 180, Issue 7 750-751 
Slone DE, Humburg JM, Jagar JE, Powers RD.Rectal tears were detected in three horses treated for colic. Based on historical, clinical, and postmortem findings, the tears could not be attributed to the attending veterinarian and were therefore not iatrogenic (physician induced). One tear was attributable to an infarction that presumably resulted from thromboembolism; 1 tear occurred without any evidence of external cause and resulted in such severe peritonitis that the cause and resulted in such severe peritonitis that the cause could not be determined, and 1 tear occurred during rectal palpation by the owner, before he called the vete...
Origin an importance of increased alkaline phosphatase activity in peritoneal fluids of horses with colic.
American journal of veterinary research    May 1, 1981   Volume 42, Issue 5 888-891 
Froscher BG, Nagode LA.The origin of increased alkaline phosphatase (ALP) activity in peritoneal fluid (PF) of horses with clinical signs of abdominal pain was investigated to determine the usefulness of measuring ALP in PF in the diagnosis of small intestinal injury. The ALP isoenzymes in PF from 10 clinically normal horses and from 50 horses with clinical signs of acute abdominal pain were analyzed for their sensitivities to inhibition by L-phenylalanine, L-homoarginine, and levamisole and to inactivation by heat (56 C, 15 minutes). The enzymes also were discriminated by their patterns of migration during polyacry...
Peritonitis in horses associated with Actinobacillus equuli.
Australian veterinary journal    June 1, 1980   Volume 56, Issue 6 296-300 doi: 10.1111/j.1751-0813.1980.tb05727.x
Gay CC, Lording PM.Actinobacillus equuli was the cause of peritonitis in 5 horses. In 3 the onset was sudden with intestinal stasis and acute abdominal pain as predominant findings. Two others presented with chronic disease and weight loss. Characteristically the peritoneal fluid had a high nucleated cell count with non-degenerate neutrophils as the predominant cell type. Four horses were treated and recovered.
Mesodiverticular bands as a cause of small intestinal strangulation and volvulus in the horse.
Journal of the American Veterinary Medical Association    November 15, 1979   Volume 175, Issue 10 1089-1094 
Freeman DE, Koch DB, Boles CL.Volvulus of the jejunum and ileum in three horses was associated with intestinal strangulation in a mesenteric rent. The rent was in the jejunal mesentery at its point of attachment with an anomaly that was classified as a mesodiverticular band. The band also was attached to the dorsolateral surface of the jejunum, thus forming one side of a triangular hernial sac that was completed on the other side by the adjacent jejunal mesentery. Incarceration of a loop of small intestine in the hernial sac preceded rupture of the jejunal mesentery and subsequent intestinal strangulation. Surgical correct...
Simulated small intestinal volvulus in the anesthetized horse.
Nordisk veterinaermedicin    November 1, 1979   Volume 31, Issue 11 466-483 
Hjortkjaer RK, Svendsen CK.Experimental closed loop small intestinal volvulus was studied in the anesthetized horse. Volvulus was simulated by ligation of the mesenterial veins to a segment of small intestine. Physical signs and hemodynamic, hematologic, clinical chemical, bacteriologic and peritoneal fluid values were examined. Compared to conscious horses anesthesia highly delayed and modified the clinical signs of shock (changes in mucosal colour, dehydration, decreased skin temperature, elevated pulse rate, low blood pressures) and of small intestinal volvulus (altered peristalsis, gastric dilation). Plasma glucose ...
Peritoneal lavage in the horse.
Journal of the American Veterinary Medical Association    August 15, 1979   Volume 175, Issue 4 388-391 
Valdez H, Scrutchfield WL, Taylor TS.Eight horses ranging in age from 4 days to 9 years were treated for peritonitis. Escherichia coli was isolated in four cases and Nocardia sp in one case. In each case, a catheter placed in the peritoneal cavity allowed drainage of a large amount of purulent fluid. Retrograde peritoneal lavage was performed through a Foley catheter or medical tubing, using Ringer's lactate solution containing kanamycin, povidone iodine, or nitrofurazone. All except two horses responded well to repeated lavage.
Tetralogy of Fallot and cranial mesenteric arteritis in a foal.
Equine veterinary journal    July 1, 1978   Volume 10, Issue 3 185-187 doi: 10.1111/j.2042-3306.1978.tb02255.x
Reynolds DJ, Nicholl TK.A 5 month old colt foal with recurrent pyrexia and a loud pansystolic murmur later developed signs of cardiac failure. Peritoneal fluid and blood samples both demonstrated an extreme leucocytosis and neutrophilia. At post-mortem both a cranial mesenteric arteritis and the congenital cardiac anomaly, Tetralogy of Fallot were found. The detailed clinical and post-mortem findings contributing to the case are described.
Clinical application of cerebrospinal fluid creatine phosphokinase determination.
Journal of the American Veterinary Medical Association    July 15, 1977   Volume 171, Issue 2 200-202 
Wilson JW.Creatine phosphokinase activity was determined in cerebrospinal fluid samples submitted for analysis from 126 animals suspected of having central nervous system disease. Values less than 1 sigma unit/ml were obtained on 32 samples and values less than or equal to 1 sigma unit/ml were obtained on 94 samples. The creatine phosphokinase values were increased in all cases of feline toxoplasmosis and feline infectious peritonitis. From other cases, especially seizure disorders and suspected poisonings, and apparent aid in prognosis for future cases was identified.
Comparison of three techniques for intestinal anastomosis in Equidae.
Journal of the American Veterinary Medical Association    July 15, 1976   Volume 169, Issue 2 208-212 
Reinertson EL.Thirteen horses and ponies were used to evaluate an anastomotic technique utilizing a modified Gambee suture pattern. The modified Gambee technique was compared with a single-row everting technique and a double-row inverting technique. The double-row inverting technique predisposed to intestinal obstruction and resulted in minimal adhesions. The everting technique predisposed to leakage of intestinal contents and subsequent peritonitis. Adhesions were formed at the site of the anastomosis to such an extent as to jeopardize the proper position of the bowel. The technique did not cause any lumin...
A clinincal evaluation of abdominal paracentesis in the horse.
Australian veterinary journal    March 1, 1976   Volume 52, Issue 3 109-117 doi: 10.1111/j.1751-0813.1976.tb05440.x
Swanwick RA, Wilkinson JS.This paper evaluates the usefulness of abdominal paracentesis as a diagnostic aid in abdominal disease in the horse and in particular considers whether or not it can be effectively utilised as an indication for surgical intervention in cases of colic. The results are based upon peritoneal fluid samples collected from 20 normal horses and from 20 cases of colic and peritonitis. Peritoneal fluid was collected from standing horses by inserting a bovine teat cannula into the horses abdomen through the linea alba after desensitisation of the skin on the ventral midline with local anaesthetic. Usual...