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Topic:Prognosis

Prognosis in horses refers to the prediction of the likely outcome or course of a disease or injury in equine patients. It involves assessing various factors such as the nature and severity of the condition, the horse's overall health, and response to treatment. Prognostic evaluations help veterinarians and horse owners make informed decisions regarding treatment options, management strategies, and potential recovery. The process often incorporates clinical assessments, diagnostic tools, and historical data to estimate the chances of recovery or progression. This page compiles peer-reviewed research studies and scholarly articles that explore methodologies, factors influencing prognostic outcomes, and the implications of prognostic evaluations in equine veterinary practice.
Serum insulin concentrations in horses with equine Cushing’s syndrome: response to a cortisol inhibitor and prognostic value.
Equine veterinary journal    May 19, 2004   Volume 36, Issue 3 295-298 doi: 10.2746/0425164044877288
McGowan CM, Frost R, Pfeiffer DU, Neiger R.Serum insulin concentration and its use as a prognostic indicator in horses with equine Cushing's syndrome (ECS) have been poorly documented. Objective: To examine daily insulin variations in horses with ECS and the effect of treatment using trilostane, a competitive inhibitor of 3beta-hydroxysteroid dehydrogenase. Further, we aimed to examine the relationship between baseline serum insulin concentration and survival in horses with ECS. Methods: Basal serum insulin concentrations were measured in 20 confirmed ECS cases by taking blood at regular 4 h intervals for 24 h (1200, 1600, 2000, 2400, ...
Results of surgical treatment of colic in miniature breed horses: 11 cases.
Australian veterinary journal    April 16, 2004   Volume 81, Issue 5 260-264 doi: 10.1111/j.1751-0813.2003.tb12566.x
Hughes KJ, Dowling BA, Matthews SA, Dart AJ.To report on the outcome of surgical treatment of acute abdominal crises in miniature breed horses. Methods: Retrospective case series of miniature horses presented to the University Veterinary Centre, Camden with an acute abdominal crisis. Methods: Hospital records of all miniature horses that underwent ventral midline laparotomy for acute abdominal crisis between 1997 and 2001 were reviewed. The signalment, history, clinical signs, results of ancillary diagnostic procedures, location and type of intestinal lesion, treatment and outcome were retrieved from each case record. Long-term survival...
Culling rate of Icelandic horses due to bone spavin.
Acta veterinaria Scandinavica    April 13, 2004   Volume 44, Issue 3-4 161-169 doi: 10.1186/1751-0147-44-161
Björnsdóttir S, Arnason T, Lord P.A survival analysis was used to compare the culling rate of Icelandic horses due to the presence of radiographic and clinical signs of bone spavin. A follow-up study of 508 horses from a survey five years earlier was performed. In the original survey 46% of the horses had radiographic signs of bone spavin (RS) and/or lameness after flexion test of the tarsus. The horse owners were interviewed by telephone. The owners were asked if the horses were still used for riding and if not, they were regarded as culled. The owners were then asked when and why the horses were culled. During the 5 years, 9...
Thoracoscopy in horses.
The Veterinary clinics of North America. Equine practice    February 27, 2004   Volume 16, Issue 2 351-vii doi: 10.1016/s0749-0739(17)30110-4
Klohnen A, Peroni JF.With the recent development of video-assisted thoracic surgery, visual inspection of the thoracic cavity has been used to provide a more accurate diagnosis and prognosis of thoracic diseases and to better manage these diseases. Equipment, techniques, and complications for standing thoracoscopy in horses are described.
Total and partial ovariohysterectomy in seven mares.
Equine veterinary journal    February 6, 2004   Volume 36, Issue 1 29-33 doi: 10.2746/0425164044864633
Rötting AK, Freeman DE, Doyle AJ, Lock T, Sauberli D.Ovariohysterectomy appears to have a low mortality rate in mares, but the procedure needs to be reviewed because of the high risk of life-threatening complications. Objective: That ovariohysterectomy can be effective treatment for a variety of uterine diseases in mares and carries a good prognosis. Methods: Diagnosis, clinical data, surgical technique, post operative care, complications and outcome were recorded from medical records of 7 mares that underwent total (6) and partial (1) ovariohysterectomy at the University of Illinois from 1994 to 2001. Results: The indications for ovariohysterec...
Treatment of peritonitis.
The Veterinary clinics of North America. Equine practice    January 27, 2004   Volume 19, Issue 3 765-778 doi: 10.1016/j.cveq.2003.08.007
Davis JL.In summary, peritonitis in the horse is a potentially life-threatening disease that must be treated promptly and aggressively. Therapy should be aimed at reducing systemic shock and hypovolemia, correction of the primary cause, antibiotic and anti-inflammatory therapy, and abdominal drainage and lavage. The prognosis depends on the ability to diagnose and treat the underlying cause and prevent the development of complications. Mortality rates can be as high as 59.7%, with horses developing postoperative peritonitis having a 56% mortality rate. Long-term complications like adhesion formation or...
Management of comminuted fractures of the proximal phalanx in horses: 64 cases (1983-2001).
Journal of the American Veterinary Medical Association    January 23, 2004   Volume 224, Issue 2 254-263 doi: 10.2460/javma.2004.224.254
Kraus BM, Richardson DW, Nunamaker DM, Ross MW.To report the outcome of surgical treatment of comminuted fractures of the proximal phalanx in horses. Methods: Retrospective study. Methods: 64 horses. Methods: Medical records and radiographs were reviewed to obtain information regarding signalment, fracture classification, and treatment. Follow-up information was obtained by telephone conversation or evaluation of production records. Results: Thirty-eight horses had moderately comminuted fractures of the proximal phalanx. Two horses were euthanatized immediately. Fractures of the proximal phalanx in 36 horses were repaired with open reducti...
Segmental ostectomy of the second and fourth metacarpal and metatarsal bones in horses: 17 cases (1993-2002).
Journal of the American Veterinary Medical Association    January 23, 2004   Volume 224, Issue 2 271-274 doi: 10.2460/javma.2004.224.271
Jenson PW, Gaughan EM, Lillich JD, Bryant JE.To determine clinical findings in and outcome of horses with fractures of the second or fourth metacarpal or metatarsal bone that underwent segmental ostectomy, leaving the proximal and distal portions of the bone undisturbed. Methods: Retrospective case series. Methods: 17 horses. Methods: Medical records were reviewed, and information on signalment, affected bone, lesion type, surgical procedure, amount of bone removed, and surgical and postsurgical complications was obtained. Follow-up information was obtained through telephone conversations with owners, trainers, and referring veterinarian...
Clinical and prognostic significance of radiographic pattern, distribution, and severity of thoracic radiographic changes in neonatal foals.
Journal of veterinary internal medicine    December 9, 2003   Volume 17, Issue 6 876-886 doi: 10.1111/j.1939-1676.2003.tb02528.x
Bedenice D, Heuwieser W, Brawer R, Solano M, Rand W, Paradis MR.A total of 207 thoracic radiographs obtained from 128 foals were evaluated to assess the impact of pulmonary radiographic pattern, distribution, and severity of pulmonary changes on short-term survival of neonatal foals. The association between selected clinical variables and the radiographic manifestation of neonatal respiratory disease was also investigated. The evaluation of interstitial and alveolar-interstitial radiographic patterns within the caudodorsal, caudoventral, and cranioventral lung regions proved to be highly reliable between viewers in the study. A diagnosis of systemic inflam...
Risk factors and prognostic variables for survival of foals with radiographic evidence of pulmonary disease.
Journal of veterinary internal medicine    December 9, 2003   Volume 17, Issue 6 868-875 doi: 10.1111/j.1939-1676.2003.tb02527.x
Bedenice D, Heuwieser W, Solano M, Rand W, Paradis MR.The medical records of 163 neonatal foals that had thoracic radiographs taken within 48 hours of admission to a referral hospital were reviewed. The objectives of this study were (1) to identify risk factors for the development of thoracic radiographic changes and (2) to identify prognostic indicators for survival in foals with radiographic evidence of pulmonary disease. Failure of transfer of passive immunity (IgG concentration < or = 400 mg/dL) was the only risk factor for radiographic evidence of respiratory disease identified by multivariate analysis. Hypoxemic patients (PaO2 1.7 mg/dL...
Retrospective study of 24 cases of septic calcaneal bursitis in the horse.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 662-668 doi: 10.2746/042516403775696285
Post EM, Singer ER, Clegg PD, Smith RK, Cripps PJ.Wounds to the plantar aspect of the tarsus present a diagnostic and treatment challenge. This study was undertaken to describe specific features of traumatic wounds involving the calcaneal bursa, with a view to determining which clinical examination findings and diagnostic tests results could provide reliable indicators of prognosis. Objective: To report clinical presentation, diagnostic findings, treatment and outcome of 24 cases of septic calcaneal bursitis; and to determine the importance of the involvement of specific anatomical structures in relation to the prognosis for survival and retu...
Results of plate fixation of type 1b olecranon fractures in 24 horses.
Equine veterinary journal    December 3, 2003   Volume 35, Issue 7 670-675 doi: 10.2746/042516403775696249
Swor TM, Watkins JP, Bahr A, Honnas CM.Previous olecranon fracture reports contain a small proportion of type 1b fractures, with only a few repaired by tension band plate fixation. Objective: To evaluate subject details, history, clinical findings and outcome of type 1b olecranon fractures in a large group of horses treated by tension band plate fixation. Methods: Medical records of 77 horses diagnosed with an olecranon fracture were reviewed. Twenty-four horses (31%) were classified as having type 1b olecranon fractures. Clinical details and follow-up results (4-128 months post operatively) were recorded. Results: Treatment includ...
Evaluation of activated neutrophils in the blood of horses with colic.
American journal of veterinary research    November 19, 2003   Volume 64, Issue 11 1364-1368 doi: 10.2460/ajvr.2003.64.1364
Weiss DJ, Evanson OA.To evaluate the activation status of neutrophils in blood samples obtained from horses with naturally occurring colic associated with strangulating obstruction, nonstrangulating obstruction, or inflammatory bowel disease. Methods: 30 horses with naturally occurring colic and 30 healthy control horses. Methods: Activation status of neutrophils was determined by assessing the number of neutrophils that could pass through filters with 5-microm pores, cell-surface CD11-CD18 expression, and alterations in size and granularity of neutrophils. Results: Horses with impaction or gas colic did not have ...
Use of nuclear scintigraphy with 99mTc-HMPAO-labelled leucocytes to assess small intestinal malabsorption in 17 horses.
The Veterinary record    October 31, 2003   Volume 153, Issue 15 457-462 doi: 10.1136/vr.153.15.457
Menzies-Gow NJ, Weller R, Bowen IM, Corley KT, Livesey L, Weaver M, Marr CM.The diagnostic and prognostic value of nuclear scintigraphy with technetium-99m-labelled hexamethyl-propyleneamine oxime-labelled leucocytes was assessed in 17 horses with weight loss due to gastrointestinal malabsorption by comparing the results with the results obtained from 13 normal control horses. Intestinal uptake of activity was detected in 12 of the 17 cases but none of the control horses. The technique was therefore specific for intestinal pathology, but failed to detect some horses that might have had intestinal pathology. No indications of the horses' specific pathology were obtaine...
Examination of the equine foot.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 309-332 doi: 10.1016/s0749-0739(03)00023-3
Turner TA.The examination of the foot must be based on observations of the hoof, followed by a careful determination of areas of pain. This must be followed by an assessment of the biomechanical forces on the hoof and limb. Finally, imaging gives insight into the nature of the injury and allows the examiner to prognosticate the outcome.
Empyema of the guttural pouch (auditory tube diverticulum) in horses: 91 cases (1977-1997).
Journal of the American Veterinary Medical Association    October 22, 2003   Volume 215, Issue 11 1666-1670 
Judy CE, Chaffin MK, Cohen ND.To identify features of guttural pouch (auditory tube diverticulum) empyema in horses and compare findings of uncomplicated guttural pouch empyema with guttural pouch empyema complicated by chondroids. Methods: Retrospective study. Methods: 91 horses with guttural pouch empyema. Methods: Medical records of horses with guttural pouch empyema were reviewed. Results: The most common owner complaint and abnormal finding was persistent nasal discharge. Chondroids were detected in 21% (19/91) of affected horses. Streptococcus equi was isolated from the guttural pouch in 14 of 44 horses; for Streptoc...
Comparison of perioperative versus postoperative intratumoral administration of cisplatin for treatment of cutaneous sarcoids and squamous cell carcinomas in horses.
Journal of the American Veterinary Medical Association    October 22, 2003   Volume 215, Issue 11 1655-1660 
Théon AP, Pascoe JR, Galuppo LD, Fisher PE, Griffey SM, Madigan JE.To determine the benefits of reducing the interval between surgical cytoreduction and intratumoral administration of cisplatin. Methods: Randomized clinical study. Methods: 70 horses with 89 incompletely resected T2- and T3-stage sarcoids (n = 64) and squamous cell carcinomas (25). Methods: Horses were given 4 intratumoral treatments of cisplatin at 2-week intervals. The first treatment was given at the time of, or immediately after, surgical resection for horses treated in accordance with the perioperative protocol (group 1). Horses in group 2 were treated with cisplatin after the skin healed...
Multicentric leiomyosarcoma in a young male horse.
Journal of the American Veterinary Medical Association    October 14, 2003   Volume 223, Issue 7 1017-986 doi: 10.2460/javma.2003.223.1017
MacGillivray KC, Graham TD, Parente EJ.A 2-year-old male Thoroughbred was evaluated for multiple firm, raised nodules of the maxilla and mandible that had been present since 6 months of age. The horse was evaluated as a yearling with a final histologic diagnosis of fibrosarcoma. As a 2-year-old, the colt made a loud upper airway sound and was agitated after strenuous exercise. Results of upper airway endoscopy indicated severe narrowing of the nasal passages and pharynx with normal resting function. Radiography revealed multiple circular bony lesions in the mandible, maxilla, multiple long bones, and cervical vertebrae. Biopsy spec...
Malignant giant cell tumor of soft parts in a mare.
The Canadian veterinary journal = La revue veterinaire canadienne    October 4, 2003   Volume 44, Issue 9 743-745 
Marryatt PA.Two subcutaneous masses were removed from the elbow of a mare. Histologically they were composed of islands of polygonal to plump spindlelioid cells with large nuclei, coarsely stippled chromatin, and eosinophilic cytoplasm. Findings were diagnostic for a malignant giant cell tumor of soft parts, a rare tumor with a fair prognosis.
Liver disease: contributions to diagnostic and prognostic aids.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 522-523 doi: 10.2746/042516403775467289
Byars TD.No abstract available
Development and application of a scoring system for prognostic evaluation of equine liver biopsies.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 534-540 doi: 10.2746/042516403775467171
Durham AE, Smitht KC, Newton JR, Hillyer MH, Hillyer LL, Smith MR, Marr CM.The study was designed to investigate the prognostic value of liver biopsy during investigation of cases of suspected liver disease in mature horses. Objective: That liver biopsy is the most prognostically useful technique in common usage in the investigation of suspected liver disease. Methods: This study examined the prognostic value of liver biopsy during the investigation of suspected liver disease in 73 mature horses. Histopathological variables comprising fibrosis, irreversible cytopathology, inflammatory infiltration, haemosiderin accumulation and biliary hyperplasia were found to be si...
Endoscopic surgery in the treatment of contaminated and infected synovial cavities.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 613-619 doi: 10.2746/042516403775467225
Wright IM, Smith MR, Humphrey DJ, Eaton-Evans TC, Hillyer MH.Contamination and infection of synovial cavities are a common occurrence in clinical practice and, if inadequately treated, may have career or life threatening consequences for affected horses. Objective: The objectives in treating contamination and infection of joints, tendon sheaths and bursae are most effectively met by endoscopic surgery. Methods: Over a 6 year period, cases of synovial contamination and infection admitted to a referral clinic were evaluated and treated endoscopically. The horses received local and systemic antimicrobial drugs with minimal nonsteroidal anti-inflammatory me...
Retrospective analysis of historical, clinical, ultrasonographic, serum biochemical and haematological data in prognostic evaluation of equine liver disease.
Equine veterinary journal    October 1, 2003   Volume 35, Issue 6 542-547 doi: 10.2746/042516403775467324
Durham AE, Newton JR, Smith KC, Hillyer MH, Hillyer LL, Smith MR, Marr CM.Results of noninvasive tests of liver disease do not always correlate with the degree of hepatic disease nor outcome of the case. Objective: To investigate the prognostic value of data collected using noninvasive tests during the investigation of cases of suspected liver disease in mature horses. Objective: Much of the data gathered during the investigation of suspected hepatopathy cases offers little prognostic guidance and interpretation of such data can be misleading. Methods: The results from a range of common and noninvasive diagnostic techniques applied in 116 mature horses with suspecte...
Meniscal tears in horses: an evaluation of clinical signs and arthroscopic treatment of 80 cases.
Equine veterinary journal    July 26, 2003   Volume 35, Issue 4 402-406 doi: 10.2746/042516403776014163
Walmsley JR, Phillips TJ, Townsend HG.There is little published information available describing clinical signs, arthroscopic findings and prognosis of meniscal injuries in horses. Objective: To evaluate the effect on the outcome not only of the arthroscopic findings and treatment, but also of the clinical and radiographic signs in these horses. Methods: The following were recorded for each case: the meniscal injury, graded according to severity; clinical and radiographic findings prior to surgery; any concurrent injury in the joint seen at arthroscopy. The effect of these factors and the grade of injury on the outcome were analys...
Prognosis in equine medical and surgical colic.
Journal of veterinary internal medicine    May 31, 2003   Volume 17, Issue 3 343-348 doi: 10.1111/j.1939-1676.2003.tb02459.x
van der Linden MA, Laffont CM, Sloet van Oldruitenborgh-Oosterbaan MM.A retrospective study was performed on 649 horses admitted to the Clinic of Equine Internal Medicine (Utrecht University) for gastrointestinal colic. The aim of this study was to provide a better guideline for determining prognosis in horses with colic. Short- and long-term survival were evaluated, and Cox regression analysis was performed to identify the clinical and clinicopathologic variables usable to predict survival. Intestinal displacements and strangulations were the most frequently diagnosed causes of colic. Regarding the surgically treated horses, 54% were discharged and 88% of these...
Cutaneous and ocular habronemiasis in horses: 63 cases (1988-2002).
Journal of the American Veterinary Medical Association    April 11, 2003   Volume 222, Issue 7 978-982 doi: 10.2460/javma.2003.222.978
Pusterla N, Watson JL, Wilson WD, Affolter VK, Spier SJ.To describe clinical manifestations of cutaneous and ocular habronemiasis in horses and evaluate outcome of treatment. Methods: Retrospective study. Methods: 63 horses. Methods: The diagnosis was made on the basis of history, clinical signs, and identification of calcified concretions (sulfur granules) in lesions. Histologic examination of biopsy specimens was used to confirm the diagnosis. Case horses were compared with a control population of 12,720 horses examined during the same period. Results: Arabians, gray horses, and horses with diluted coat colors were overrepresented; Thoroughbreds ...
Desmitis of the straight sesamoidean ligament in horses: 9 cases (1995-1997).
Journal of the American Veterinary Medical Association    April 11, 2003   Volume 222, Issue 7 973-977 doi: 10.2460/javma.2003.222.973
Schneider RK, Tucker RL, Habegger SR, Brown J, Leathers CW.To determine clinical signs, diagnostic findings, and outcome for horses with desmitis of the straight sesamoidean ligament (SSL) near its insertion on the middle phalanx. Methods: Retrospective study. Methods: 9 horses. Methods: Medical records were reviewed, and information on signalment, history, clinical signs, diagnostic findings, and treatment was obtained. Follow-up information was obtained through telephone conversations with owners. Results: In all horses, the diagnosis was made by use of high-resolution ultrasonography. Seven horses had moderate lameness on initial examination; lamen...
[Laryngeal infection by Rhodococcus equi in patient with AIDS].
Acta otorrinolaringologica espanola    March 28, 2003   Volume 53, Issue 10 783-788 doi: 10.1016/s0001-6519(02)78376-3
Pardo Mateu L, Faubel Serra M, Llavero Segovia MT, Cano Cuenca B, Pérez Climent F, Giménez Vaillo F, Grau Alario E, Lazaro Santander R.The Rhodococcus equi is an aerobic gram positive pleomorphic bacillus, that was isolated for the first time like a producer of bronchopneumonia in young horses. Every time more often, it is being recognized as a pathogen in humans, mainly in the immunodepressed population. We described a case, until now exceptional, of laryngeal infection by Rhodococcus equi in a patient with positive serology for the virus of the human immunodeficiency (HIV), and we reviewed some clinical and epidemiological characteristics of the infections by this germ. The treatment is riphampicine and/or erythromycin, bei...
Stress fractures of the tibia and humerus in Thoroughbred racehorses: 99 cases (1992-2000).
Journal of the American Veterinary Medical Association    February 25, 2003   Volume 222, Issue 4 491-498 doi: 10.2460/javma.2003.222.491
O'Sullivan CB, Lumsden JM.To determine clinical characteristics of and outcome in Thoroughbred racehorses with tibial or humeral stress fractures. Methods: Retrospective study. Methods: 99 Thoroughbreds with tibial or humeral stress fractures. Methods: Information obtained from the medical records included history, signalment, and clinical, radiographic, and scintigraphic findings. Outcome was determined by interviewing trainers, performing follow-up examinations, and analyzing race records. Results: Seventy-four tibial stress fractures were identified in 61 Thoroughbreds, and 48 humeral stress fractures were identifie...
Use of a hydroxyapatite orbital implant in a cosmetic corneoscleral prosthesis after enucleation in a horse.
Journal of the American Veterinary Medical Association    February 5, 2003   Volume 222, Issue 3 343-316 doi: 10.2460/javma.2003.222.343
Gilger BC, Pizzirani S, Johnston LC, Urdiales NR.A hydroxyapatite orbital implant was used after enucleation of an eye from a 5-year-old performance horse. A custom-made corneoscleral prosthesis was made and fitted over the hydroxyapatite implant. The implant and surgery were well tolerated. Placement of a cosmetic prosthesis is desired after enucleation of equine eyes to allow horses to return to competition. Synthetic spheres consisting of methylmethacrylate or silicone have been used, although reported complications have included extrusion, infection, and poor cosmetic results. Hydroxyapatite orbital implants made from marine coral allow ...
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