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Topic:Treatment

Treatments for horses encompasses a range of medical and therapeutic interventions aimed at maintaining or restoring equine health. This field involves the use of pharmaceuticals, surgical procedures, and alternative therapies to address various conditions affecting horses. Common treatments include the administration of anti-inflammatory drugs, antibiotics, and vaccines, as well as physical therapies and nutritional management. Research in this area focuses on evaluating the efficacy, safety, and outcomes of different treatment modalities. This page collects peer-reviewed research studies and scholarly articles that explore the methods, advancements, and clinical outcomes associated with equine treatment practices.
Esophageal duplication cyst as a cause of choke in the horse.
Journal of the American Veterinary Medical Association    August 15, 1988   Volume 193, Issue 4 474-476 
Orsini JA, Sepesy L, Donawick WJ, McDevitt D.A mare was examined for episodic choking and an abscess in the perilaryngeal region. One month before referral, the mass progressively enlarged, causing esophageal choking. An extraluminal compression of the esophagus 90 cm from the external nares was found on endoscopy and contrast radiography. Serosanguinous fluid aspirated from the mass contained keratinized squamous cells and neutrophils, compatible with an esophageal cyst. Surgical exploration was performed, with incomplete surgical excision. The remaining portion of the cyst was marsupialized and treated locally with a 2% inorganic iodin...
Ultrasonic imaging of equine ovarian follicles and corpora lutea.
The Veterinary clinics of North America. Equine practice    August 1, 1988   Volume 4, Issue 2 197-213 doi: 10.1016/s0749-0739(17)30636-3
Ginther OJ.One of the most profound theriogenology applications of transrectal diagnostic ultrasonography in mares involves the imaging of ovarian follicles and corpora lutea. The resolving capabilities (frequency) and quality of the scanner directly affect the minimal size of a structure that can be imaged and the quality of the image. High-frequency scanners (5 or 7.5 MHz) of good quality can image a 2-mm follicle and the corpus luteum throughout its functional life. A low-frequency scanner (3 or 3.5 MHz) can image a 6-mm follicle and the corpus luteum for several days after ovulation. Equine follicles...
Systemic therapy with aminoglycoside antibiotics in the horse.
Australian veterinary journal    July 1, 1988   Volume 65, Issue 7 197-198 doi: 10.1111/j.1751-0813.1988.tb14455.x
Dyke TM.No abstract available
Corynebacterium folliculitis in a horse.
Journal of the American Veterinary Medical Association    July 1, 1988   Volume 193, Issue 1 89-90 
Heffner KA, White SD, Frevert CW, Jakowski R.A 7-year-old Thoroughbred was examined for evaluation of mildly pruritic multiple skin lesions that had progressed from nodules to alopecia and crusts. Folliculitis caused by Corynebacterium pseudotuberculosis was diagnosed by bacterial culture. Oral treatment with a trimethoprimsulfadiazine paste resulted in resolution of all lesions, with normal hair regrowth.
Verification of ineffectual activity of ivermectin against adult Onchocerca spp in the ligamentum nuchae of horses.
American journal of veterinary research    July 1, 1988   Volume 49, Issue 7 983-985 
Lyons ET, Drudge JH, Tolliver SC.Ivermectin paste formulation (200 micrograms/kg) was administered orally to 27 horses (13 Thoroughbreds and 14 of mixed breeding) to evaluate activity against adult Onchocerca spp in the ligamentum nuchae. Ages, known or estimated, of the horses ranged from 1 to 22 years. Single or multiple doses (1 to 5) of the drug were given to each horse. When multiple doses were administered, the intervals between treatments ranged from 7 to 92 days. At 27 to 171 days after initial treatment (single dose or first of multiple doses), the horses were killed. Some of the horses treated more than once were ki...
Adverse reaction to procaine penicillin G in horses.
Australian veterinary journal    June 1, 1988   Volume 65, Issue 6 181-185 doi: 10.1111/j.1751-0813.1988.tb14296.x
Nielsen IL, Jacobs KA, Huntington PJ, Chapman CB, Lloyd KC.Adverse reactions to intramuscular injections of procaine penicillin G are reported in 11 horses, five of which died. The clinical findings are presented and suggest central nervous involvement in most cases. Post mortem findings in one horse were consistent with anaphylaxis whereas in other cases the clinical findings, duration of treatment, speed of onset and subsequent completion of treatment supports diagnosis of an acute procaine toxicity syndrome.
The pathogenesis and treatment of osteomyelitis and laminitis in a stallion after the prolonged topical application of formalin to the distal phalanx.
Australian veterinary journal    June 1, 1988   Volume 65, Issue 6 185-188 doi: 10.1111/j.1751-0813.1988.tb14297.x
Dart AJ, Pascoe RR.A 12-year-old Quarterhorse stallion was presented with a severe lameness in the left forefoot. There was a 3 cm diameter cavity in the sole that extended to the solar surface of the distal phalanx. Radiographs revealed an osteomyelitis and a sequestrum which probably developed following the prolonged topical application of 10 percent formalin. The sequestrum was removed and the infected bone curetted under general anaesthesia. The horse was shod with heart bar shoes on both front feet 7 days after the surgery. Eight months later, radiographs showed marked rotation of the distal phalanx despite...
Use of lag screw fixation for repair of a central tarsal bone fracture in a horse.
Journal of the American Veterinary Medical Association    May 15, 1988   Volume 192, Issue 10 1451-1452 
Ramey DW.An 8-year-old Thoroughbred gelding was determined to have a sagittal fracture of the central tarsal bone. Lag screw fixation of the fracture enabled the horse to return to jumping, although degenerative arthritis of the distal intertarsal joint was apparent radiographically 17 months after the injury.
Electrohydraulic lithotripsy for the treatment of cystic calculus in two geldings.
Equine veterinary journal    May 1, 1988   Volume 20, Issue 3 221-223 doi: 10.1111/j.2042-3306.1988.tb01505.x
Eustace RA, Hunt JM, Brearley MJ.No abstract available
High-frequency jet ventilation in a neonatal foal.
Journal of the American Veterinary Medical Association    April 1, 1988   Volume 192, Issue 7 920-922 
Bain FT, Brock KA, Koterba AM.High-frequency jet ventilation was performed on a premature foal for respiratory difficulty attributable to in utero-acquired pneumonia. The procedure involves delivery of compressed gas through a small-bore cannula at frequencies up to 400 cycles/min. Ventilation settings of drive pressure, frequency, and FIO2 were varied to optimize PaO2 and PaCO2 values. The foal was ventilated with this equipment for 14 hours. Evidence of a favorable response to this method of ventilation was observed in the form of improvement in arterial blood gas values as well as the foal's attitude and degree of respi...
Intensive care of the patient after abdominal surgery.
The Veterinary clinics of North America. Equine practice    April 1, 1988   Volume 4, Issue 1 79-89 doi: 10.1016/s0749-0739(17)30651-x
Fischer AT.After surgical correction of the underlying abdominal disorder, careful postoperative care is the most important factor resulting in increased survival rates. Intensive care of the postoperative patient can be done practically and economically.
Hemodynamic and respiratory responses in halothane-anesthetized horses exposed to positive end-expiratory pressure alone and with dobutamine.
American journal of veterinary research    April 1, 1988   Volume 49, Issue 4 539-542 
Swanson CR, Muir WW.The influence of positive end-expiratory pressure (PEEP) on the alveolar-arterial O2 tension difference [P(A-a)O2], physiologic right-to-left shunt fraction, physiologic dead space-to-tidal volume ratio, and hemodynamic variables was studied in halothane-anesthetized horses maintained in dorsal recumbency during controlled ventilation. Dobutamine was used to minimize the adverse cardiovascular consequences of PEEP. Six adult horses were anesthetized, using xylazine (2.2 mg/kg of body weight, IM), guaifenesin (50 mg/kg, IV), thiamylal Na (4.4 mg/kg, IV), and halothane (1.5 to 2% inspired) in 10...
Incomplete palmar fracture of the proximal extremity of the third metacarpal bone in horses: ten cases (1981-1986).
Journal of the American Veterinary Medical Association    March 15, 1988   Volume 192, Issue 6 798-803 
Lloyd KC, Koblik P, Ragle C, Wheat JD, Lakritz J.In 4 adult horses, simple, nondisplaced, incomplete fracture of the proximal extremity of the third metacarpal bone (MC3) was identified radiographically only on the dorsopalmar projection. Lameness was slight to moderate. Although nerve blocks of the foot and fetlock did not alter the lameness, high palmar regional nerve block improved the gait in 1 of the 2 horses on which it was performed. Pain on palpation or swollen distal accessory (inferior check) ligament, flexor tendons, and suspensory ligament were not found in any horse. The fracture was localized to the palmar surface of the proxim...
Dose-dependent plasma elimination of subcutaneously administered calcium heparin in horses.
Journal of veterinary pharmacology and therapeutics    March 1, 1988   Volume 11, Issue 1 77-83 doi: 10.1111/j.1365-2885.1988.tb00124.x
Gerhards H, Kietzmann M.Pharmacokinetic parameters for subcutaneous low dose heparin in horses have been determined. Four groups of five and one group of eleven mature, healthy horses of various breeds were given single subcutaneous injections of 60, 80, 100, 125, and 150 units of calcium heparin/kg of body weight (U/kg) in the pectoral region. Jugular blood samples were collected prior to, and at hourly intervals for 12 h after injection. Heparin plasma concentrations were measured using a commercially available amidolytic assay. Peak concentrations 4 h after administration were 0.021 +/- 0.016 (mean +/- SD) units o...
Pharmacokinetics of sodium amoxicillin in horses.
Research in veterinary science    March 1, 1988   Volume 44, Issue 2 233-236 
Montesissa C, Carli S, Sonzogni O, Garlappi R.The pharmacokinetics of sodium amoxicillin were investigated after intravenous and intramuscular administration of a single dose of 15 mg kg-1 body-weight to five horses. A rapid distribution phase was noted after intravenous administration (t1/2 alpha about 20 minutes). The t1/2 beta values obtained after the intravenous and the intramuscular administration were significantly different (P less than 0.05). The bioavailability obtained was about 67 per cent. Plasma protein binding, evaluated in vitro, showed that the percentage of bound fraction was 37 to 38 per cent. It was concluded that sodi...
Effect of beta-tricalcium phosphate in surgically created subchondral bone defects in male horses.
American journal of veterinary research    March 1, 1988   Volume 49, Issue 3 417-424 
Rose PL, Auer JA, Hulse D, Hightower D, Schenk RK.beta-Tricalcium phosphate (TCP) was evaluated as a synthetic bone grafting material in horses. Sixteen horses were randomly assigned to 4 groups of 4 horses. In each horse, an 11-mm by 10-mm circular defect with a smooth margin was created surgically in the weight-bearing surface of both third metacarpal bones (McIII) and the left third metatarsal bone. The defect in the left McIII was filled with TCP, the defect in the right McIII was filled with a mixture of 50% autogenous cancellous bone (ACB) and 50% TCP, and the defect in the left third metatarsal bone was not filled to serve as a control...
Pharmacokinetics of ticarcillin and clavulanic acid given in combination to adult horses by intravenous and intramuscular routes.
Journal of veterinary pharmacology and therapeutics    March 1, 1988   Volume 11, Issue 1 103-108 doi: 10.1111/j.1365-2885.1988.tb00102.x
Sweeney RW, Beech J, Simmons RD, Soma LR.The pharmacokinetics of ticarcillin and clavulanic acid following administration by the intravenous (i.v.) and intramuscular (i.m.) routes were investigated in six normal adult horses. Following i.v. administration, the ticarcillin disposition data conformed to a two-compartment model with an elimination half-life of 1.0 h. The disposition of clavulanic acid was described by a one-compartment model with an elimination half-life of 0.40 h. Following i.m. administration, the half-lives of both drugs were prolonged (ticarcillin 1.8 h, clavulanic acid 1.2 h). The bioavailability of ticarcillin was...
The effect of 9a-fluoroprednisolone on the pathogenicity of Microsporum canis and Trichophyton violaceum to horses.
Mycoses    February 1, 1988   Volume 31, Issue 2 71-79 
Abu-Samra MT, Ibrahim KE.No abstract available
Concurrent mercuric blister and dimethyl sulphoxide (DMSO) application as a cause of mercury toxicity in two horses.
Equine veterinary journal    January 1, 1988   Volume 20, Issue 1 68-71 doi: 10.1111/j.2042-3306.1988.tb01459.x
Schuh JC, Ross C, Meschter C.No abstract available
Osseous sequestration in the horse. A review of 68 cases.
Veterinary surgery : VS    January 1, 1988   Volume 17, Issue 1 2-5 doi: 10.1111/j.1532-950x.1988.tb00267.x
Clem MF, DeBowes RM, Yovich JV, Douglass JP, Bennett SM.Sixty-eight cases of cortical bone sequestration in 67 equine patients were reviewed with regard to the clinical presentation, method of treatment, and outcome. All lesions were located in skeletal areas with minimal soft tissue coverage, with 53% of them in the metatarsal and metacarpal bones. At the time of admission, 60% of the patients with limb lesions were lame; the majority improved with therapy. After sequestrectomy, there was a trend for surgical wounds which could be managed by primary closure to heal more rapidly (3.8 weeks) than wounds which required second intention healing (6.4 w...
[Changes in several blood and urine parameters during combined hyperfluid therapy for the treatment of chronic obstructive bronchitis (COB) in the horse].
Tierarztliche Praxis    January 1, 1988   Volume 16, Issue 2 167-173 
Rapp HJ.During the combination of oral and intravenous application of saline solution for treatment of the COPD of horses the level of hydraemia basing on the total protein concentration in the serum, the urine production and the specific weight of urine was determined. Additionally the development of serum concentration and of renal excretion rates of potassium, calcium and magnesium were ascertained. The level of hydraemia resulting from the combined method is almost identical with the solely intravenous performed hyperinfusion therapy. Due to the excessive application of fluid an extremely high lev...
Chronic flunixin meglumine therapy in foals.
American journal of veterinary research    January 1, 1988   Volume 49, Issue 1 7-12 
Traub-Dargatz JL, Bertone JJ, Gould DH, Wrigley RH, Weiser MG, Forney SD.Effects of a therapeutic dose of flunixin meglumine on gastric mucosa of horse foals were determined by endoscopy, double-contrast radiography, and gross and histologic examinations. Foals were administered 1.1 mg of flunixin meglumine/kg of body weight, PO/day for 30 days in an encapsulated form that was divided into 2 doses/day (group 1; n = 3) or by IM injection once a day (group 2; n = 7). Three control foals (group 3; n = 3) were administered capsules (n = 1) containing dextrose powder or IM injections (n = 2) of vehicle solution without flunixin meglumine. All 3 groups-1 foals given flun...
Comparison of the effects of two sets of anaesthetic agents and posture on respiratory rate, heart rate, pH, blood gas and acid-base status in the horse.
The British veterinary journal    November 1, 1987   Volume 143, Issue 6 506-512 doi: 10.1016/0007-1935(87)90039-X
Karimi A.Two methods of anaesthesia were evaluated in the horse for their effects on the cardiovascular and respiratory systems and on the acid-base status of the animal. In addition the effect of the position—dorsal and lateral recumbency—of the anaesthetized horse on these systems was evaluated.
Equine respiratory medicine and surgery.
Equine veterinary journal    September 1, 1987   Volume 19, Issue 5 370-487 
No abstract available
Use of a bone plate for treatment of middle phalangeal fractures in horses: seven cases (1979-1984).
Journal of the American Veterinary Medical Association    September 1, 1987   Volume 191, Issue 5 575-578 
Doran RE, White NA, Allen D.Four adult horses and 3 foals with middle phalangeal fractures were treated by arthrodesis of the proximal interphalangeal joint, using a bone plate. Six of the 7 horses survived greater than 2 years; 2 of the 6 horses had intermittent lameness after hard work, and 4 horses didn't have evidence of lameness. The use of a bone plate for arthrodesis of the proximal interphalangeal joint was a successful treatment alternative for middle phalangeal fractures in horses.
Preputial hematoma in a stallion.
Journal of the American Veterinary Medical Association    September 1, 1987   Volume 191, Issue 5 563-564 
Memon MA, McClure JJ, Usenik EA.An 8-year-old Quarter Horse stallion was admitted with a swelling involving the prepuce, dorsal part of the scrotum, and root of the penis. The swelling was first noticed 10 days after breeding, with no evidence that it had resulted from a kick by the mare. The penis was retracted into the prepuce, except for a 10- to 15-cm protrusion of the glans penis. Treatment included warm hydrotherapy, massage, stockinette compression, antidiuretics, antibiotics, penile support, and exercise, without success. At necropsy, a massive preputial hematoma was found extending forward from the root of the penis...
Surgical management of proximal splint bone fractures in the horse.
Veterinary surgery : VS    September 1, 1987   Volume 16, Issue 5 367-372 doi: 10.1111/j.1532-950x.1987.tb00969.x
Peterson PR, Pascoe JR, Wheat JD.Fractures of Metacarpal and Metatarsal II and IV (the splint bones) were treated in 283 horses over an 11 year period. In 21 cases the proximal portion of the fractured bone was stabilized with metallic implants. One or more cortical bone screws were used in 11 horses, and bone plates were applied in 11 horses. One horse received both treatments. Complications of screw fixation included bone failure, implant failure, radiographic lucency around the screws, and proliferative new bone at the ostectomy site. Only two of the horses treated with screw fixation returned to their intended use. Compli...
Outcome of treatment in 35 cases of guttural pouch mycosis.
Equine veterinary journal    September 1, 1987   Volume 19, Issue 5 483-487 doi: 10.1111/j.2042-3306.1987.tb02649.x
Greet TR.This paper describes the outcome of treatment of 30 cases of guttural pouch mycosis by ligation of the internal carotid artery on the cardiac side of the lesion and lavage of the affected pouch with natamycin. Twenty-three horses recovered fully following this treatment while laryngeal hemiplegia persisted in one case and slight dysphagia caused by pharyngeal hemiplegia in another. The remaining five horses died or were destroyed. Five horses with guttural pouch mycosis, which had shown no epistaxis but had pharyngeal hemiplegia, were treated by topical natamycin alone. Only two of these survi...
Paranasal sinusitis complicated by inspissated exudate in the ventral conchal sinus.
Veterinary surgery : VS    September 1, 1987   Volume 16, Issue 5 373-377 doi: 10.1111/j.1532-950x.1987.tb00970.x
Schumacher J, Honnas C, Smith B.Primary paranasal sinusitis complicated by inspissated exudate within the ventral conchal sinus was diagnosed in five horses. Clinical signs included a unilateral, foul-smelling, mucopurulent nasal exudate of 2 to 7 months' duration. Two of the horses had partial nasal obstruction from distortion of the ventral concha. Radiographs of the skull showed a mass of soft tissue density dorsal to the roots of the superior third and fourth or fourth and fifth cheek teeth. Treatment included bone flap maxillary sinusotomy with exposure of the ventral nasal concha and removal of inspissated exudate. Res...
Equine degenerative myeloencephalopathy.
The Veterinary clinics of North America. Equine practice    August 1, 1987   Volume 3, Issue 2 379-383 doi: 10.1016/s0749-0739(17)30680-6
Beech J.This article discusses the history and signalment, clinical signs, differential diagnosis, pathology, etiology and pathogenesis, and treatment and prevention of equine degenerative myeloencephalopathy.
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