Veterinary care in horses encompasses the medical and preventive measures taken to maintain and improve the health and well-being of equine patients. It includes a wide range of practices such as routine health examinations, vaccinations, dental care, parasite control, and management of injuries and diseases. Veterinary care also involves diagnostic procedures, surgical interventions, and therapeutic treatments tailored to the specific needs of horses. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of equine veterinary care, including advancements in diagnostic techniques, treatment protocols, and health management strategies to support the well-being and performance of horses.
Vanderwall DK, Rasmussen DM, Woods GL.To determine whether IM administration of exogenous oxytocin twice daily on days 7 to 14 after ovulation blocks luteolysis and causes prolonged function of corpora lutea (CL) in mares. Methods: Prospective study. Methods: 12 mares. Methods: Beginning on the day of ovulation (day 0), jugular blood samples were collected every other day until day 40 for determination of progesterone concentration. On day 7, mares (n = 6/group) were treated with saline (0.9% NaCl) solution (control group) or oxytocin. Beginning on day 7, control mares received 3 mL of sterile saline solution every 12 hours, IM, a...
Sullivan KA, Hill AE, Haussler KK.Common methods used to treat back problems in horses need to be assessed objectively. Objective: To measure spinal mechanical nociceptive thresholds (MNTs) and evaluate the effects of chiropractic, massage and phenylbutazone, compared with active and inactive control groups. Methods: Baseline MNTs at 7 sites within the thoracolumbar and sacral regions were measured in 38 healthy mature horses exhibiting no clinical signs of lumbar pain. Horses were assigned to one of 3 treatment groups: instrument-assisted chiropractic treatment, therapeutic massage and phenylbutazone; or 2 control groups: rid...
Javsicas LH, Sanchez LC.Administration of omeprazole paste per os to healthy neonatal foals has been shown to effectively increase intragastric pH, but has not been evaluated in sick neonatal foals. Objective: To determine the effect of orally administered omeprazole paste on intragastric pH in clinically ill neonatal foals requiring nasogastric intubation. Methods: Intragastric pH was measured continuously for 24 h using an indwelling electrode and continuous data recording system in hospitalised neonatal foals age < or =2 days. Intragastric pH was measured for 12 h prior to (pretreatment period) and 12 h followi...
Dixon PM, Barakzai S, Collins N, Yates J.Cheek teeth (CT) diastemata are a significant cause of painful dental disease in horses and limited factual information is available on the treatment of this disorder. Objective: To assess the response to mechanical widening in the treatment of diastema. Methods: Details of the presenting signs and treatment of cases of CT diastema by widening were recorded and the response to treatment of these cases assessed by re-examinations and by obtaining follow-up information from owners. Results: Sixty horses of various breeds, median age 9 years, with clinically significant CT diastemata were classif...
Noble GK, Brockwell YM, Munn KJ, Harris PA, Davidson HP, Li X, Zhang D, Sillence MN.L-tryptophan is a common ingredient in equine calmative products, but its effectiveness has not been demonstrated in horses. Objective: To determine whether a commercial dose of L-tryptophan increases plasma tryptophan and alters behaviour in horses fed a roughage or concentrate meal. Methods: L-tryptophan (6.3 g) or placebo (water) was administered per os in a cross-over design, to 12 Thoroughbred horses (503 +/- 12.1 kg bwt), just before a meal of lucerne hay or oats. Plasma tryptophan was measured by gas chromatography. Horse behaviour was observed in an empty enclosure, then in the presenc...
Johnson L, Thompson DL, Varner DD.Testicular function is under the control of expression and repression of several genes and gene products, and many of these works through Sertoli cells. The capability of Sertoli cells to regulate spermatogenesis is dependent on Sertoli cell functions and Sertoli cell number. Sertoli cell number has long been thought to be stable in adults with no proliferation of Sertoli cells once adult numbers have been reached. However, adult horses do not have stable Sertoli cell numbers, and new studies indicate that adult Sertoli cells can be made to re-enter mitotic phase under certain experimental con...
Rashid HB, Chaudhry M, Rashid H, Pervez K, Khan MA, Mahmood AK.The present work was conducted to study the comparative efficacy of two anti-protozoan (babesicidal) drugs on the recovery and health of horses. A total of 80 horses, showing typical clinical symptoms of the disease, were selected for this study; the presence of babesiosis was confirmed through blood smear examination. These animals were divided into two groups i.e. A and B. Horses of Group A, were treated with diminazene diaceturate, while horses of Group B were treated with diminazene aceturate. Efficacy of the drugs was determined by the reversal of clinical signs and a negative blood smear...
Watanabe T, Imamura Y, Hosaka Y, Ueda H, Takehana K.By using ultramorphological and biochemical methods, we analyzed the regional differences between the three parts of the equine superficial digital flexor tendon (SDFT), namely, the myotendinous junction (MTJ), middle metacarpal (mM), and osteotendinous junction (OTJ). Cross-sectional images showed unique distributions of collagen fibrils of varying diameters in each region. Small collagen fibrils (diameter 200 nm). In the mM region, the collagen fibrils were intermediately distributed between the MTJ and OTJ. The results indicate a graded arrangement of collagen fibrils in the tendon. Type V ...
Kasashima Y, Takahashi T, Birch HL, Smith RK, Goodship AE.Tendons can be considered in two functional groups, those contributing to energetics of locomotion and those acting solely to position the limb. The energy-storing tendons in both human and equine athletes have a high frequency of injury with similar pathophysiology. In previous studies, high-intensity exercise appears to induce a disruption of the matrix rather than functional adaptation in adults. Here we explore the hypothesis that the introduction of controlled exercise during growth would result in an adaptive response without deleterious effects. Young horses were given a controlled exer...
Lindegaard C, Husted L, Ullum H, Fjeldborg J.Endoscopy of the upper airways of horses is used as a diagnostic tool and at purchase examinations. On some occasions it is necessary to use sedation during the procedure and it is often speculated that the result of the examination might be influenced due to the muscle-relaxing properties of the most commonly used sedatives. Objective: To evaluate the effect of detomidine (0.01 mg/kg bwt) and acepromazine (0.05 mg/kg bwt) on the appearance of symmetry of rima glottidis, ability to abduct maximally the arytenoid cartilages and the effect on recurrent laryngeal neuropathy (RLN) grade. Methods: ...
Hughes TK, Eliashar E, Smith RK.To examine the anatomic relationship of the deep branch of the lateral plantar nerve (DBLPN) with structures of the proximal metatarsal region, and to define the anatomic location of a solution injected using a single injection technique for diagnostic analgesia of the proximal suspensory ligament (PSL). Methods: Descriptive study. Methods: Cadaveric equine pelvic limbs (n=29). Methods: The proximal metatarsal region of both pelvic limbs (n=5 horses, 10 limbs) was dissected and measurements were made of anatomic structures relative to the head of the 4th metatarsal bone (HMT4). A single inject...
Valentine BA, Löhr CV.Three horses with colic, clinical evidence of endotoxaemia and high serum activities of creatine kinase and aspartate aminotransferase were examined postmortem. The horses were diagnosed with severe ulcerative colitis, pyloric ulceration and stenosis with colonic sand impaction, and colonic obstruction due to faecaliths. There was no gross or histological evidence of muscle trauma. Their semimembranosus muscles had scattered acute to subacute segmental necrosis of the myofibres, suggestive of endotoxin-induced muscle injury.
Lefranc A-, Allen WR.The morphology and surface density of endometrial glands responsible for the nutrition of the placenta requires further study employing computer assisted morphometric analysis. Objective: To analyse changes in the morphology and surface density of endometrial glands situated adjacent to, and remote from, the conceptus during the first 30 days of gestation. Methods: Endometrial biopsies were recovered, under videoendoscopic control, from both nonpregnant and pregnant mares 12 days after ovulation, as well as from pregnant mares on Days 16, 20, 25 and 30 of gestation. One biopsy was taken at the...
Nimmo MR, Slone DE, Hughes FE, Lynch TM, Clark CK.To report fertility (foals conceived, live foal births) of mares after partial fetotomy to resolve dystocia and complications associated with fetotomy. Methods: Retrospective study. Methods: Horses (n=20). Methods: Medical records (2001-2006) of mares that had partial fetotomy (1-3 cuts) for dystocia were reviewed. Complications and subsequent fertility were obtained by interview and live foal data were recorded by the Jockey Club. Postfetotomy conception and live foals produced over 21 breeding seasons (defined as years each mare was bred regardless of conception) were recorded. Results: Twen...
Sod GA, Mitchell CF, Hubert JD, Martin GS, Gill MS.To compare in vitro monotonic biomechanical properties of an equine spoon plate (ESP) with an axial 3-hole, 4.5 mm narrow dynamic compression plate (DCP) using 5.5 mm cortical screws in conjunction with 2 abaxial transarticular 5.5 mm cortical screws (DCP-TLS) inserted in lag fashion for equine proximal interphalangeal (PIP) joint arthrodesis. Methods: Paired in vitro biomechanical testing of 2 methods of stabilizing cadaveric adult equine forelimb PIP joints. Methods: Cadaveric adult equine forelimbs (n=18 pairs). Methods: For each forelimb pair, 1 PIP joint was stabilized with an ESP (8 hole...
Chaney KP.Congenital anomalies of the urinary tract in horses may be difficult to diagnose and treat. Presenting complaints are variable and include weight loss, depression, dysuria, hematuria, and mild colic. Although the most severe abnormalities are diagnosed in the neonate, some diseases, such as ectopic ureter(s), may be identified in older horses. In human medicine, the fetus is examined in the prenatal period for evidence of urinary tract dysfunction, but this is not yet common practice in equine medicine. As a result, urinary tract anomalies are diagnosed after birth using a wide variety of diag...
Wilson ME.Pathologic conditions of the urinary tract may produce specific clinical signs, but they are more than likely to be nonspecific clinical signs, which often occur with chronic renal disease in addition to countless other diseases. Further, clinical signs that may seem to be directly related to the urinary tract may be the result of other systemic diseases. Thus, before embarking on diagnostics, it is important to obtain a thorough history and physical examination.
Arroyo LG, Stämpfli HR.Renal tubular disorders have been sporadically reported in horses. Only three types of tubular defects have been recognized: (1) nephrogenic diabetes insipidus, attributable to unresponsiveness of the renal tubules to antidiuretic hormone; (2) distal renal tubular acidosis (RTA; type I); and (3) proximal RTA (type II). The following review focuses on RTA and nephrogenic diabetes insipidus.
McKenzie EC.Polyuria and polydipsia provide a diagnostic challenge for the equine clinician. This article describes the various known causes of polyuria and polydipsia in horses and provides a description of a systematic diagnostic approach for assessing horses with polyuria and polydipsia to delineate the underlying cause. Treatment and management strategies for addressing polyuria and polydipsia in horses are also described.
Schmitz DG.Many different substances can induce toxic damage to various structural components of the equine kidney, and most lack pathognomonic signs. Some of these agents have specific treatments, although many do not. Supportive and symptomatic therapy is an important aspect of treatment of most cases of equine nephrotoxicosis. Regardless of cause, if the toxic substance is removed or neutralized before significant renal damage, full recovery of renal function may occur. Many horses already have significant renal damage before a definitive diagnosis is made, and the prognosis for full recovery thus rem...
Schott HC.Chronic renal failure is a syndrome of progressive loss of renal function that results in loss of urinary concentrating ability, retention of nitrogenous and other metabolic end products, alterations in electrolyte and acid-base status, and dysfunction of several hormone systems. This article describes the prevalence, causes, clinical signs, diagnostic evaluation, and management of horses afflicted with chronic renal failure. It is hoped that this article illustrates that chronic renal failure, when detected in the earlier stages of disease, can be managed successfully in the short-term allowi...
Delguste C, de Moffarts B, Kirschvink N, Art T, Pincemail J, Defraigne JO, Amory H, Lekeux P.The antioxidant status of 10 horses living in stable 1 where 2 cases of equine motor neuron disease had previously been diagnosed was assessed before and 9 weeks after moving to another stable. Duration of residence in stable 1, subsequent moving, or both, significantly affected several parameters of the antioxidant status. Le statut antioxydatif de 10 chevaux logés dans l’écurie 1, où 2 cas de maladie du neurone moteur avaient été précédemment diagnostiqués, a été vérifié avant et 9 semaines après leur transfert dans une autre écurie. La durée de l’hébergement dans l’é...
Toribio RE.Knowledge of urinary tract anatomy and the numerous functions of the kidney in regulating fluids, electrolytes, acid-base balance, and waste products improves the ability of the clinician to diagnose, treat, and make appropriate recommendations for the management of the horse with renal disease. Several conditions can directly or indirectly affect renal function on a temporary or permanent basis. Endogenous and exogenous compounds (eg, drugs, toxins, hemoglobin) alone or in combination with inappropriate renal blood flow can promote or exacerbate renal disease.
Schumacher J.Hematuria and pigmenturia of horses are discussed in this article. Equine urine is normally straw colored. Discolored urine can be caused by contamination with red blood cells, hemoglobin, myoglobin, oxidizing agents normally found in urine, and plant-derived pigments.
Williamson A, Rogers CW, Firth EC.To identify feeding and management variables associated with variation in faecal pH within a population of intensively managed Thoroughbred racehorses in New Zealand. Methods: A cross-sectional survey was conducted of 16 racehorse trainers in the North Island of New Zealand. Interviews were conducted at the trainers' stables to obtain information on feeding and management of horses, and faecal samples were collected and faecal pH measured. Results: Ninety-seven percent of the horses surveyed were confined in an area or=12 h/day. Trainer's age, number of years they had trained horses, age and g...
Akagami M, Shibahara T, Yoshiga T, Tanaka N, Yaguchi Y, Onuki T, Kondo T, Yamanaka T, Kubo M.A ten-year-old Shetland pony gelding showed low appetite, ataxia, peculiar swaying, clouding of consciousness, and ultimately died. At necropsy, multiple coalescing granulomatous foci were detected in the kidneys, and small necrotic lesions were found in the cerebellum. Histologic examination of the renal tissue sections revealed extensive granuloma, and Halicephalobus gingivalis-like nematodes were seen. Similar nematodes were found in the granulomatous or necrotic lesions of the renal lymph nodes and cerebellum, and were also frequently detected in cerebrospinal meningovascular lesions. Morp...
Geor RJ.Acute renal failure (ARF) in horses is usually prerenal or renal in origin and is most often caused by hemodynamic or nephrotoxic insults. The clinical management of patients that have ARF is largely supportive, including correction of fluid deficits and electrolyte and acid-base disturbances and treatment and reversal of the underlying cause. Use of dopamine and mannitol to promote renal blood flow and urine output is no longer recommended.
Stratton LG, Corstvet R, Brown J, Corley L.K. pneumoniae capsule type 68 infused into the uterus of 4 mares was recovered up to 15 weeks after inoculation. The insertion of a tampon for 10 min was more effective than a swab technique in detecting the organism in the uterus. The clitoral fossa and the urethral orifice when sampled by the swab technique were also found to be infected for a comparable period. K. pneumoniae was isolated from the clitoral specimens more often and more consistently than from either urethral or uterine specimens.
Geiser DR.Chemical restraint in the standing horse is used for a variety of procedures in veterinary medicine. The choice of agent depends on the physical status, temperament, and size of the patient; the procedure to be performed; and safety for the patient, veterinarian, and owner. The combination of certain agents may provide more desirable restraint and analgesia than does the use of individual agents. The use of analgesics in the horse is not without side effects, some of which may be detrimental to the patient's condition. Analgesics should be chosen with these untoward effects in mind. Draft bree...
J Lacy K, Parlane NA, Riley CB, Gee EK, Roberts JM, McIlwraith CW.CellTrace Violet™ is a commonly used fluorescent dye used with flow cytometry to identify cell proliferation. Activated equine lymphocytes were examined using flow cytometry, microscopy and tritiated thymidine proliferation assays. CellTrace Violet™ was incorporated into the equine lymphocytes effectively. Equine lymphocytes proliferated when activated with pokeweed mitogen, but did not proliferate when previously stained with CellTrace Violet™. Serial dilutions of CellTrace Violet™ did not eliminate the inhibition of activated lymphocytes. Equine lymphocyte viability was greater than ...
Cauvin ER, Munroe GA, Boswell J, Boyd JS.This study was undertaken to establish the gross anatomy and the ultrasonographic appearance of the carpal digital flexor tendon sheath (carpal sheath) and the palmar carpal region in normal horses. The isolated forelimbs from 15 horses were used to study the morphology of the sheath and associated structures, including a detailed study of the location of the main blood vessels and nerves in that region. These limbs and the forelimbs of five live, sound horses were also examined ultrasonographically. The examination yielded good soft tissue detail of the tendons and ligaments, synovial and per...
Santos MP, Gutierrez-Nibeyro SD, Horn GP, Johnson AJ, Stewart MC, Schaeffer DJ.To compare the mechanical properties of laryngeal tie-forward (LTF) surrogate constructs prepared with steel fixtures and No. 5 braided polyester or braided polyethylene by use of a standard or a modified suture placement technique. Methods: 32 LTF surrogate constructs. Methods: Surrogate constructs were prepared with steel fixtures and sutures (polyester or polyethylene) by use of a standard or modified suture placement technique. Constructs underwent single-load-to-failure testing. Maximal load at failure, elongation at failure, stiffness, and suture breakage sites were compared among constr...
Sielhorst J, Roggel-Buecker U, Neudeck KC, Kahler A, Rohn K, Luettgenau J, Bollwein H, Hollinshead F, Sieme H.The aim of this double-blinded placebo-controlled study was to investigate the effect of acetylsalicylic acid (ASA) on uterine blood flow, gestation length, placental and foal weights in pregnant mares. Sixteen Thoroughbred mares of different age (13.3 ± 4.1) and parity (7.4 ± 3.1) were randomly assigned to three treatment groups. Mares in group C (n = 4) served as controls and received 5,000 mg lactose orally once daily from D 120 (D 0 = day of ovulation) until parturition. Mares in group ASA1 (n = 7) received 5,000 mg ASA orally once daily from D 120 until parturition. Mares in group...
Meuten DJ, Price SM, Seiler RM, Krook L.Pseudohyperparathyroidism was diagnosed in a mature stallion presented for anorexia, weight loss, pollakiuria and constipation. Laboratory findings included hypercalcemia, hypophosphatemia, anemia and isosthenuria. Thoracocentesis indicated an exfoliating squamous cell carcinoma. At necropsy, a squamous cell carcinoma of the stomach with metastases to the abdominal and thoracic cavities was diagnosed. No osseous metastases were found. No gross or microscopic renal lesions were noted. Bone tissue showed arrested resorption, and the parathyroid gland was atrophic.
Matthews AG, Crispin SM, Parker J.A wide range of fundic variants are encountered during routine ophthalmoscopic examination of visually normal horses, often causing the examiner difficulty in assessing their clinical significance. Many of these are anatomical variants having no significant effect on visual function, and lie within the limits of normality in the horse. This paper illustrates this range of variants and discusses their anatomical basis and physiological consequences. Colobomata are non-progressive discontinuities in the structure of the anatomic fundus, occasionally noted as incidental findings during ophthalmos...
Karagianni AE, Summers KM, Couroucé A, Depecker M, McGorum BC, Hume DA, Pirie RS.Mild-to-moderate equine asthma is prevalent in young racehorses, particularly early in their training period. Although the precise etiopathogenesis remains undetermined, it is possible that the susceptibility of this population might partly reflect an exercise-associated immune derangement at the level of the airway. We performed a genome-wide basal gene expression scan on alveolar macrophages (AMs) isolated from Standardbred racehorses before and after commencement of competition race training with a view to identifying any exercise-associated gene expression modulation consistent with functi...
Ray AC, Dwyer JN, Fambro GW, Reagor JC.4-Aminopyridine poisoning in horses was diagnosed. Specific methods, utilizing thin-layer and high-performance liquid chromatography, were developed for determining the compound in stomach contents and corn bait. The lethal dose was estimated at 2 to 3 mg/kg of body weight.
Cullinane M, O'Sullivan E, Collins DM, Byrne AW, More SJ.Recently, considerable international attention has been paid to the problem of unwanted horses. In Ireland, stray horses, particularly in urban areas, are a further problem. The Control of Horses Act 1996 was enacted in response to an ongoing problem of uncontrolled horses in public places. As yet, no research work has been conducted focusing on stray horses in Ireland. This paper describes horses impounded under the Act in the Munster region of Ireland during 2005-2012 and the factors influencing decisions regarding their disposal. A logistic regression model was developed to investigate fact...
Anderson GA, Mount ME, Vrins AA, Ziemer EL.Acorn poisoning was diagnosed in an 11-year-old Quarter Horse with signs of severe colic, tachycardia, hyperpnea, abdominal borborygmus, rectal tenesmus, and hemorrhagic diarrhea. The diagnosis was based on history and predisposing factors, clinical signs, laboratory data, acorn husks in the feces, the urinary gallic acid equivalent concentration, and necropsy findings. The most striking pathologic changes were gastrointestinal and mesenteric edema, ulcerative enterocolitis, and nephrosis.
Kuwano A, Ueno T, Katayama Y, Nishiyama T, Arai K.Between the laminar epidermis and the laminar dermis of laminar region (LR) in equine foot, it can be observed the basement membrane zone (BMZ), which is composed of a basement membrane and its accompaniments like the hemidesmosome and anchoring fibril. Alteration in the BMZ in equine laminitis is possibly related with not only development but also recovery outcome and recurrence of this disease. However, there is little known about the structure of the BMZ during the recovery phase of this disease. To assess the condition of the BMZ of LR affected by chronic laminitis, the tissue was examined...
Southwood LL, Cohen J, Busschers E, Habecker P.To report a case of multiple acquired jejunal pseudodiverticula managed successfully by resection and jejunojejunostomy. Methods: Clinical report. Methods: Arabian filly. Methods: The filly was referred for signs of acute colic of several hours duration and had a 2-week history of inappetence and weight loss. Three meters of thickened, edematous, and dilated jejunum removed during exploratory celiotomy had an intussusception and numerous diverticula; jejunojejunostomy performed. The pathoanatomic diagnosis was proliferative enteropathy with pseudodiverticula formation and jejunal muscular hype...
Schenzel S, Rohde C, Fugazzola MC.A three-week-old warmblood colt was referred for a two-week history of lameness on the left thoracic limb, and a two-month-old Quarter Horse-mix filly was referred for malaligned pelvic limbs since birth. The foals were diagnosed with agenesis and dysgenesis of the navicular bone, respectively. In this report, we present clinical signs, diagnostics, and postmortem workup of the two cases.