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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Experimental exposure of pregnant mares to the asinine-94 strain of equine arteritis virus.
Journal of the South African Veterinary Association    June 1, 1997   Volume 68, Issue 2 49-54 doi: 10.4102/jsava.v68i2.869
Paweska JT, Henton MM, van der Lugt JJ.Clinical, virological and serological responses were evaluated in 10 pregnant mares after different challenge exposures to the asinine-94 strain of equine arteritis virus (EAV). The outcome of maternal infection on the progeny was also investigated. Mares were inoculated intranasally (n = 4), intramuscularly (n = 2), intravenously (n = 1), or contract-exposed (n = 3). All inoculated mares developed pyrexia, 5 showed mild clinical signs related to EAV infection and 2 remained asymptomatic. Viraemia was detected in all the inoculated animals and shedding of virus from the respiratory tract occur...
Identification and treatment of the compromised equine fetus: a clinical perspective.
Equine veterinary journal. Supplement    June 1, 1997   Issue 24 100-103 doi: 10.1111/j.2042-3306.1997.tb05086.x
LeBlanc MM.No abstract available
Lack of local anaesthetic efficacy of Sarapin in the abaxial sesamoid block model.
Journal of veterinary pharmacology and therapeutics    June 1, 1997   Volume 20, Issue 3 229-232 doi: 10.1111/j.1365-2885.1997.tb00100.x
Harkins JD, Mundy GD, Stanley SD, Sams RA, Tobin T.Sarapin is a distillate of the pitcher plant that has long been used in human and veterinary medicine for 'regional analgesia'. The mechanism of the reported analgesic response is unknown; however, the agent is purported to provide more effective analgesia for slow, chronic pain than for sharp, acute pain. Reportedly, Sarapin is also widely used as an analgesic agent in the horse, generally in combination with corticosteroids and other agents. To determine its local anaesthetic efficacy in the horse, we tested Sarapin in a unilateral abaxial sesamoid block model at two dose levels, 2 mL and 10...
Controlled dose confirmation study of a 2% moxidectin equine gel against equine internal parasites in The Netherlands.
Veterinary parasitology    June 1, 1997   Volume 70, Issue 1-3 165-173 doi: 10.1016/s0304-4017(96)01135-1
Eysker M, Boersema JH, Grinwis GC, Kooyman FN, Poot J.The efficacy of a 2% moxidectin equine gel at a dosage rate of 0.4 mg kg-1 was evaluated in a controlled trial at Utrecht University. Twelve yearling castrated male Shetland ponies grazed a pasture of 2 ha from May 1994 until housing in November. Six ponies were treated with moxidectin, whereas the others served as non-treated controls. Necropsy was carried out 35 days after treatment. Greater than 99% efficacy of moxidectin was observed on faecal egg output. No effect of moxidectin was observed on mucosal inhibited early cyathostome L3 (EL3) or on the total numbers of mucosal developing stage...
Effect of the South African asinine-94 strain of equine arteritis virus (EAV) in pregnant donkey mares and duration of maternal immunity in foals.
The Onderstepoort journal of veterinary research    June 1, 1997   Volume 64, Issue 2 147-152 
Paweska JT.Clinical, virological and serological responses were investigated in five pregnant donkey mares after experimental exposure to the South African asinine-94 strain of equine arteritis virus (EAV), and the duration of maternal immunity to EAV was studied in their foals. In four intranasally inoculated mares, fever with maximum rectal temperatures of 39.1-40.7 degrees C was recorded 2-11 d after challenge. All the inoculated mares developed mild depression, and a serous ocular and nasal discharge; in three mares mild conjuctivitis was observed. The virus was recovered from the nasopharynx and fro...
Plasma alpha-tocopherol, beta-carotene, and lipid levels in semi-free-ranging Przewalski horses (Equus przewalskii). Dierenfeld ES, Hoppe PP, Woodford MH, Krilov NP, Klimov VV, Yasinetskaya NI.Circulating concentrations of alpha-tocopherol, beta-carotene, and lipids were quantified in 19 Przewalski horses (Equus przewalskii) inhabiting the steppes of Ukraine during June 1991. Foals (n = 3) had lower mean plasma alpha-tocopherol (4.7 micrograms/ml) and beta-carotene (0.3 microgram/ml) levels than did adults (n = 16; 6.6 and 0.7 micrograms/ml, respectively) and higher mean cholesterol concentrations (1.42 vs. 0.98 mg/ml). Mean triglyceride levels did not differ between foals and adults (0.46 mg/ml). Alpha tocopherol concentrations were substantially higher than those considered normal...
[Development of nutrition science in veterinary medicine as an example of the School of Veterinary Medicine Hannover].
DTW. Deutsche tierarztliche Wochenschrift    June 1, 1997   Volume 104, Issue 6 203-207 
Meyer H.Animal nutrition is not a main subject in veterinary medicine training, nevertheless it has been taught in the Tierärztliche Hochschule Hannover since its foundation in 1778. In the very beginning only a few lectures about feedstuffs and toxic plants for horses and feeding technique have been presented. During the 19th century animal nutrition was taught about 20 h under the general topic: Gesundheitspflege or Dlätetik. Diätetik included in that time all factors which are important for health as soil, water, climate, stable, hamess and nutrition, too. Textbooks about "Gesundheitspflege" fro...
Prevalence of equine piroplasmosis in Central Mongolia.
The Onderstepoort journal of veterinary research    June 1, 1997   Volume 64, Issue 2 141-145 
Avarzed A, De Waal DT, Igarashi I, Saito A, Oyamada T, Toyoda Y, Suzuki N.Antigen for the indirect fluorescent antibody test (IFAT) was routinely prepared from infected erythrocytes from horses experimentally infected with Babesia equi and Babesia caballi. With the successful establishment of in vitro cultures of B. equi and B. caballi, it is now possible to employ culture-derived antigens in this test. In this study, in vitro-propagated B. equi- and B. caballi-infected erythrocytes were used as antigen in the IFAT. Various modifications to an established protocol had to be implemented to allow repeatable results. Cultures with 3-4% parasitized erythrocytes were fou...
Comparative fetal and neonatal physiology: reviews in memory of Marian Silver.
Equine veterinary journal. Supplement    June 1, 1997   Issue 24 I-117 
No abstract available
Effect of insulin-induced hypoglycaemia on secretion patterns and rates of corticotrophin-releasing hormone, arginine vasopressin and adrenocorticotrophin in horses.
The Journal of endocrinology    June 1, 1997   Volume 153, Issue 3 401-409 doi: 10.1677/joe.0.1530401
Alexander SL, Roud HK, Irvine CH.To study the effect of hypoglycaemia on secretion rates of corticotrophin-releasing hormone (CRH), arginine vasopressin (AVP) and ACTH in a non-ruminant species, a non-surgical method was used to collect pituitary venous (PitVen) blood every 0.5 or 1 min from seven horses before and after insulin administration (0.4 U/kg i.v.). To assess the effect of PitVen cannulation on results, peripheral hormones were also measured before and after insulin in five horses without PitVen cannulae. Insulin administration lowered plasma glucose in all horses (P < 0.0001; paired t-test). Cortisol concentrat...
Pharmacokinetic study of dipyrone metabolite 4-MAA in the horse and possible implications for doping control.
Journal of veterinary pharmacology and therapeutics    June 1, 1997   Volume 20, Issue 3 204-208 doi: 10.1111/j.1365-2885.1997.tb00096.x
Klaus AM, Schlingloff Y, Kleinitz U, Böttcher M, Hapke HJ.The pharmacokinetic behaviour of dipyrone metabolite 4-MAA in serum was determined in seven horses of different breeds after a single intravenous dose administration. A biexponential formula was fitted to the serum concentration vs. time data. The median half-life of the elimination phase (t1/2 beta) was 4.85 h (range 5.04 h), the median volume of distribution (Vd(area)) was 1.85 L/kg (range 3.2 L/kg) and median of total clearance was 4.0 mL/min/kg (range 2.3 mL/min/kg).
Additional research on tendon strains and stresses.
American journal of veterinary research    June 1, 1997   Volume 58, Issue 6 569-570 
Crevier-Denoix N, Pourcelot P.No abstract available
Varices with thrombosis in the cervix and uterus of a mare.
The Canadian veterinary journal = La revue veterinaire canadienne    June 1, 1997   Volume 38, Issue 6 375-376 
Foster RA, Gartley CJ, Newman S.Cervical and uterine varices with thrombosis were observed at the necropsy of a virgin 16-year-old Peruvian Paso that had previous episodes of hemorrhage from the uterus. Practitioners and pathologists should be alert to the possibility of ruptured varices in mares with hemorrhage into the uterus or from the vulva.
Catecholamines, enkephalins and the response of the fetal adrenal medulla to hypoxaemia.
Equine veterinary journal. Supplement    June 1, 1997   Issue 24 68-73 doi: 10.1111/j.2042-3306.1997.tb05081.x
McMillen IC, Simonetta G, Roberts ML, Adams MB.No abstract available
Microscopic anatomy of the ungulate placenta.
Equine veterinary journal. Supplement    June 1, 1997   Issue 24 7-13 doi: 10.1111/j.2042-3306.1997.tb05072.x
Macdonald AA, Fowden AL.No abstract available
Design complexity and fracture control in the equine hoof wall.
The Journal of experimental biology    June 1, 1997   Volume 200, Issue Pt 11 1639-1659 doi: 10.1242/jeb.200.11.1639
Kasapi MA, Gosline JM.Morphological and mechanical studies were conducted on samples of equine hoof wall to help elucidate the relationship between form and function of this complex, hierarchically organized structure. Morphological findings indicated a dependence of tubule size, shape and helical alignment of intermediate filaments (IFs) within the lamellae on the position through the wall thickness. The plane of the intertubular IFs changed from perpendicular to the tubule axis in the inner wall to almost parallel to the tubule axis in the outer wall. Morphological data predicted the existence of three crack dive...
Antibodies against some viruses of domestic animals in southern African wild animals.
The Onderstepoort journal of veterinary research    June 1, 1997   Volume 64, Issue 2 95-110 
Barnard BJ.Twenty-four species of South African wild animals were tested for the presence of antibodies against the viruses of 16 common diseases of domestic animals. Positive results were obtained for African horsesickness, equine encephalosis, equid herpes virus-1, infectious bovine rhinotracheitis, Allerton disease (Herpes mammillitis), lumpy skin disease, parainfluenza, encephalomyocarditis, bluetongue, Wesselsbron disease, bovine ephemeral fever, and Akabane disease complex. No antibodies could be demonstrated against the viruses of equine influenza, equine infectious anaemia, equine viral arteritis...
Cloning, sequencing and in vitro functional expression of recombinant donkey follicle-stimulating hormone receptor: a new insight into the binding specificity of gonadotrophin receptors.
Journal of molecular endocrinology    June 1, 1997   Volume 18, Issue 3 193-202 doi: 10.1677/jme.0.0180193
Richard F, Martinat N, Remy JJ, Salesse R, Combarnous Y.Among all mammalian FSH receptors (FSH-R; including donkey (dk) FSH-R), only horse (hs) FSH-R does not bind hsLH/chorionic gonadotrophin (CG). In order to delineate the structural origin of hsFSH-R specificity precisely, we have cloned dkFSH-R cDNA from donkey testis mRNA by RT-PCR. Transiently expressed dkFSH-R endowed COS-7 cells with both hsLH/CG- and FSH-binding activity, as well as FSH-induced cAMP production. The deduced dkFSH-R amino acid sequence shares 96% identity with the hsFSH-R: notably, in the hormone-binding domain, the specificity of hsFSH-R may be ascribed to only four diverge...
Effect of transportation on lower respiratory tract contamination and peripheral blood neutrophil function.
Australian veterinary journal    June 1, 1997   Volume 75, Issue 6 433-438 doi: 10.1111/j.1751-0813.1997.tb14349.x
Raidal SL, Bailey GD, Love DN.To evaluate the effect of transportation on lower respiratory tract contamination and peripheral blood neutrophil function in horses and to compare results from transported horses with those obtained in earlier experiments from horses confined with heads elevated. Methods: A prospective study. Methods: Six horses were transported by road for 12 h. Clinical and haematological examination, transtracheal aspiration and cell function studies were conducted before and after transportation. Results obtained after transportation were compared to pre-transportation values. Results: After transportatio...
Characterization and mutational studies of equine infectious anemia virus dUTPase.
Biochimica et biophysica acta    May 23, 1997   Volume 1339, Issue 2 181-191 doi: 10.1016/s0167-4838(96)00229-4
Shao H, Robek MD, Threadgill DS, Mankowski LS, Cameron CE, Fuller FJ, Payne SL.The macrophage tropic lentivirus, equine infectious anemia virus (EIAV), encodes a dUTPase in the pol gene that is required for efficient replication in macrophages. Two naturally occurring variants of the enzyme were expressed as recombinant proteins in Escherichia coli; metal chelate affinity chromatography was used to purify histidine-tagged recombinant enzymes to greater than 80% homogeneity in a single chromatographic step. Biochemical and enzymatic analyses of these preparations suggest that this method yields dUTPase that is suitable for detailed mutational analysis. Specific activities...
[The incidence of multiple ovulations in Dutch warmblood mares].
Tijdschrift voor diergeneeskunde    May 15, 1997   Volume 122, Issue 10 277-279 
Willink DL, Smeenk LA, van Oijen PW, de Kruif A.In the period 1994-1996 1030 oestruses of Dutch Warmblood mares were evaluated on the incidence of multiple ovulations diagnosed by rectal palpation. Ultrasonography was not used. All follicles > 25 mm were noted. The examination was repeated every 48 hours. The incidence of multiple follicle development was 7.3%. In a group of 50 ultrasonographically diagnosed twin-pregnant mares only 14 (28%) had been detected by rectal palpation as a multiple ovulation. This suggests an incidence of multiple ovulations in Dutch Warmblood mares of 7.3 x 1/28 x 100 = 26%. Restrictions of rectal palpation are ...
The effect of strenuous versus moderate exercise on the metabolism of proteoglycans in articular cartilage from different weight-bearing regions of the equine third carpal bone.
Osteoarthritis and cartilage    May 1, 1997   Volume 5, Issue 3 161-172 doi: 10.1016/s1063-4584(97)80011-8
Little CB, Ghosh P, Rose R.Articular cartilage degeneration in the middle carpal joint is a common problem in racing horses. This study evaluated the effect of exercise on the in-vitro synthesis of the large aggregating proteoglycans (aggrecan) and two small proteoglycans, biglycan and decorin, in articular cartilage taken from three weight bearing regions of the third carpal bone of horses which were subjected to moderate or strenuous exercise. Twelve Standardbred horses free from clinical and radiographic disease of the middle carpal joint were subjected to an 8 week moderate exercise program. The horses were then ran...
Compensatory movements of horses with a stance phase lameness.
Equine veterinary journal. Supplement    May 1, 1997   Issue 23 102-105 doi: 10.1111/j.2042-3306.1997.tb05065.x
Uhlir C, Licka T, Kübber P, Peham C, Scheidl M, Girtler D.In order to study the mechanism of lameness transfer from fore- and hindlimb lamenesses 2 hypotheses were investigated. Hypothesis 1: Horses with a true supporting limb lameness in one hindlimb show a false supporting limb lameness in the ipsilateral forelimb. Hypothesis 2: Horses with a true supporting limb lameness in one forelimb show a false supporting limb lameness in the contralateral hindlimb. Fourteen horses with fore- or hindlimb lameness were used for this study. Each horse was measured at the trot on a treadmill with standardised speed, before and after diagnostic blocks (9 horses),...
Equine dentistry: evolution and structure.
Equine veterinary journal    May 1, 1997   Volume 29, Issue 3 169-170 doi: 10.1111/j.2042-3306.1997.tb01663.x
Gorrel C.No abstract available
Severe nasal hemorrhage in an anesthetized horse.
Journal of the American Veterinary Medical Association    May 1, 1997   Volume 210, Issue 9 1324-1327 
Trim CM, Eaton SA, Parks AH.An 8-year-old Thoroughbred gelding with colic was anesthetized for surgical correction of right dorsal displacement of the ascending colon. Removal of the nasogastric tube at the end of surgery resulted in hemorrhage from the nares and loss of 24 L of blood. Treatment included administration of acetated Ringer's solution, hypertonic saline solution, and dobutamine. A blood transfusion was started after hemorrhage was controlled, and arterial pressure was restored to the prehemorrhage value, but was stopped after infusion of 2.7 L of blood because of a suspected adverse reaction. This case indi...
Diaphragmatic hernia repair in three young horses.
Veterinary surgery : VS    May 1, 1997   Volume 26, Issue 3 242-245 doi: 10.1111/j.1532-950x.1997.tb01492.x
Santschi EM, Juzwiak JS, Moll HD, Slone DE.This clinical report describes surgical correction of diaphragmatic hernia in three young horses. Methods: Retrospective investigation of medical records and subsequent racing performance. Methods: Three young horses with diaphragmatic hernia. Results: Three young horses with signs of abdominal pain had diaphragmatic hernia causing small intestinal strangulation. The strangulated small intestine was resected and an end-to-end jejuno-jejunal (two horses) or a side-to-side jejuno-cecal anastomosis (one horse) was performed. Diaphragmatic hernias were closed with a continuous suture pattern. All ...
Equine dendritic cell infection with equid herpesvirus type 1 reduces their ability to support mitogenic T cell proliferation.
Biochemical Society transactions    May 1, 1997   Volume 25, Issue 2 283S doi: 10.1042/bst025283s
Siedek EM, Edington N, Hamblin A.No abstract available
Variability of the limb joint patterns of sound horses at trot.
Equine veterinary journal. Supplement    May 1, 1997   Issue 23 89-92 doi: 10.1111/j.2042-3306.1997.tb05062.x
Degueurce C, Pourcelot P, Audigié F, Denoix JM, Geiger D.The reproducibility of gait variables for sound horses is essential for the interpretation of their modifications by locomotor disorders. Therefore, the purpose of this study was to evaluate the variability of the limb joint angle patterns in a population of sound horses while they trotted in the conditions of the routine lameness examination (slow trot, just held by hand, on a track, outdoors). The kinematics of 14 French Saddle horses was recorded using a 3-dimensional (3D) kinematic analysis system. Angle-time diagrams were established in the sagittal plane and their intra- and inter-indivi...
Cloning of equine type II procollagen and the modulation of its expression in cultured equine articular chondrocytes.
Matrix biology : journal of the International Society for Matrix Biology    May 1, 1997   Volume 16, Issue 2 59-64 doi: 10.1016/s0945-053x(97)90073-1
Richardson DW, Dodge GR.The complete nucleotide sequence of equine type II procollagen has not been previously reported, and equine-specific probes have not been available. We report the complete sequence and discuss the molecular characteristics of equine type II procollagen mRNA which was cloned from a cDNA library prepared from mRNA isolated from equine articular chondrocytes. The coding sequence (4257 bp) was 92.4% homologous to the cDNA of the human sequence, and the propeptide was 97% identical to the human sequence. We demonstrated that when equine chondrocytes are grown in phenotypically-maintained cultures, ...
Temporal effects of an infusion of dopexamine hydrochloride in horses anesthetized with halothane.
American journal of veterinary research    May 1, 1997   Volume 58, Issue 5 516-523 
Young LE, Blissitt KJ, Clutton RE, Molony V.To evaluate the hemodynamic effects of a 60-minute infusion of dopexamine in horses anesthetized with halothane. Methods: 7 adult Thoroughbreds. Methods: Measurements of left ventricular function obtained by transesophageal Doppler echocardiography and cardiac catheterization. Results: Infusion of dopexamine (4 micrograms/kg of body weight/min) significantly increased heart rate, cardiac output, maximal rates of increase and decrease of left ventricular pressure, and maximal acceleration and maximal velocity of aortic blood flow. Left ventricular ejection time significantly increased, and pre-...