Veterinary procedures in horses encompass a range of medical and surgical interventions performed to diagnose, treat, and manage equine health conditions. These procedures are designed to address various health issues, from routine care to emergency interventions. Common veterinary procedures include vaccinations, dental care, lameness evaluations, reproductive services, and surgical interventions such as colic surgery or fracture repair. This page compiles peer-reviewed research studies and scholarly articles that explore the methodologies, outcomes, and advancements in veterinary procedures for horses, providing insights into their application and efficacy in equine medicine.
Kremer A, Ribitsch I, Reboredo J, Dürr J, Egerbacher M, Jenner F, Walles H.Meniscal injuries are the most frequently encountered soft tissue injuries in the equine stifle joint. Due to the inherent limited repair potential of meniscal tissue, meniscal injuries do not only affect the meniscus itself but also lead to impaired joint homeostasis and secondary osteoarthritis. The presented study compares 3D coculture constructs of primary equine mesenchymal stem cells (MSC) and meniscus cells (MC) seeded on three different scaffolds-a cell-laden collagen type I hydrogel (Col I gel), a tissue-derived small intestinal matrix scaffold (SIS-muc) and a combination thereof-for ...
Stauffer S, Cordner B, Dixon J, Witte T.The aim of this preliminary proof-of-concept study was to evaluate and compare the success and complication rate of infiltration of the maxillary nerve of cadaver heads using previously described surface landmarks, standard ultrasound and a novel needle guidance positioning ultrasound system (SonixGPS). Methods: Prospective, anatomical, method-comparison study. Methods: Thirty-eight equine cadaver heads. Methods: Twenty-six veterinary students performed the three methods consecutively on cadaver heads using an 18 gauge, 8.9 cm spinal needle and 0.5Â mL iodinated contrast medium. Computed tomog...
Allen SE, Rosanowski SM, Stirk AJ, Verheyen KLP.No large-scale studies have described veterinary events occurring in National Hunt (NH) flat racing or investigated risk factors for fatality in this race type. Objective: To describe injuries and conditions requiring veterinary attendance on race day and to determine risk factors for racehorse fatality in NH flat racing in Great Britain. Methods: Retrospective cohort study (2000-2013). Methods: Information from all NH flat races held over the study period, including horse, race and veterinary event report details, was combined. Veterinary events were described by type and anatomical structure...
Leathwick DM, Sauermann CW, Geurden T, Nielsen MK.A previously described model for the dynamics of the parasitic stages of Parascaris spp. was modified to include eggs outside the host and the genetics of anthelmintic resistance before being used to address questions regarding the development of resistance. Three broad questions were addressed; i) How sustainable is the current common practice of treating foals monthly for their first year of life (i.e. 12 treatments/year)? ii) Does the timing of treatments have an effect on resistance development? (i.e. do certain treatments select for resistance more strongly than others?), and iii) How sus...
Stieler Stewart AL, Sanchez LC, Mallicote MF, Muniz AL, Westerterp MS, Burrow JA, MacKAY RJ.Erythromycin (ERY) induces anhidrosis in foals. Azithromycin (AZI) and clarithromycin (CLA), often combined with rifampicin (RIF), are commonly used to treat Rhodococcus equi infections, but effects on sweating have not been investigated. Objective: To determine the effects of AZI, CLA and RIF on sweat responses in normal foals. Methods: Each experiment was a blinded, duplicated, six foal × three period counterbalanced within subjects design (12 foals/experiment). Methods: Antimicrobials were given orally for 5 days. In Experiment 1, ERY, AZI and CLA were given. In Experiment 2, ERY, RIF and ...
Pongratz U, Licka T.The aim of this study was to provide information on algometric transmission of pressure through the dorsal thoracolumbar tissues of the equine back. Using a commercially available algometer, measurements were carried out with six different tips (hemispheric and cylindrical surfaces, contact areas 0.5Â cm2, 1Â cm2, and 2Â cm2). In nine live horses the threshold of pressure that lead to any reaction was documented. In postmortem specimens of five euthanized horses the transmission of algometer pressure onto a pressure sensor placed underneath the dorsal thoracolumbar tissues at the level of the ...
Stanley SD, Moffitt K, Wiebe V.Equine practitioners should follow these recommendations when using compounded medications: (1) the decision must be veterinary driven, based on a valid veterinarian-client-patient relationship and on evidence-based medicine; (2) compliance with the Animal Medicinal Drug Use Clarification Act of 1994; and (3) use limited to (a) horses for which no other method or route of drug delivery is practical; (b) those drugs for which safety, efficacy, and stability have been demonstrated; or (c) disease conditions for which a quantifiable response to therapy or drug concentration can be monitored.
Roquet I, Lane Easter J, Coomer RPC, Ezquerra LJ, Marsh CA, Trostle SS, Santschi EM.To describe the results of screw placement through subchondral lucencies (SCL) of the proximal radius in 8 horses. Methods: Retrospective clinical study. Methods: Horses with cubital SCL causing lameness (n=8). Methods: Medical record review and clinical follow-up. Results: Eight horses with SCL in the proximal radius causing lameness were treated with a screw placed across the lucency. The horses range in age from 1 to 20 years. In 4 of 8 horses, the lameness had been intermittently severe (apparent at the walk). Lameness was isolated to the cubital joint by intra-articular anesthesia in 5 ho...
Lang HM, Schnabel LV, Cassano JM, Fortier LA.Mesenchymal stem cells (MSCs) are frequently delivered via needle injection for treatment of musculoskeletal injuries. The purpose of this study was to evaluate the effect of needle diameter on the viability of MSCs. Methods: Equine bone marrow-derived MSCs from 5 horses were suspended in PBS, and held at room temperature for 7 hours to mimic shipping conditions. Two replicate samples for each needle size (20, 22, 23, or 25-gauge [ga]) were aspirated into a 3 mL syringe and re-injected into the holding vial 3 times, to reproduce the resuspension of cells prior to injection in clinical cases. C...
Heliczer N, Mitchell K, Lorello O, Dauvillier J, Burger D, Schwarzwald CC, Navas de Solis C.A 20-year-old warmblood breeding stallion presented to a University practice for semen collection and evaluation was incidentally diagnosed with atrial fibrillation (AF). Electrocardiogram recordings during breeding revealed inappropriately rapid tachycardia and occasional ventricular premature depolarizations/aberrant ventricular conduction. Transvenous electrical cardioversion was performed. After successful cardioversion the horse displayed supraventricular ectopy and atrial contractile dysfunction and was administered sotalol hydrochloride in an attempt to decrease the risk of AF recurrenc...
Hewetson M, Sykes BW, Hallowell GD, Tulamo RM.Equine gastric ulcer syndrome (EGUS) is common in adult horses, particularly those involved in performance disciplines. Currently, detection of EGUS by gastroscopy is the only reliable ante mortem method for definitive diagnosis; however it is unsuitable as a screening test because it is expensive, time consuming, and is not readily available to most veterinarians. Sucrose permeability testing represents a simple, economical alternative to gastroscopy for screening purposes, and the feasibility of this approach in the horse has been previously reported. The aim of this study was to determine t...
Schnobrich MR, Gordon DL, Scoggin CF, Bradecamp EA, Canisso IF.Urine pooling, as a persistent condition, is a cause of infertility in mares due to endometrial inflammation and sperm toxicity. Identification of urometra can be challenging in mares presenting with the condition intermittently, or when urine flows into the uterus but is undetectable in the vagina. Currently, there are no reported objective methods to confirm the clinical diagnosis of urine contamination in intrauterine-fluid accumulations. Since creatinine is present in high concentrations in urine and does not diffuse across cell membranes, creatinine concentration should be increased in ma...
Knych HK, Stanley SD, Harrison LM, Mckemie DS.The use of corticosteroids, such as betamethasone, in performance horses is tightly regulated. The objective of the current study was to describe the plasma pharmacokinetics of betamethasone as well as time-related urine and synovial fluid concentrations following intra-articular administration to horses. Twelve racing-fit adult Thoroughbred horses received a single intra-articular administration (9Â mg) of a betamethasone sodium phosphate and betamethasone acetate injectable suspension into the right antebrachiocarpal joint. Blood, urine, and synovial fluid samples were collected prior to and...
Raidal SL, Burnheim K, Evans D, Hughes KJ.Sedation is often required to perform pulmonary function testing (PFT) in horses, but drug effects may influence respiratory function. The current study was designed to characterise the effects of sedation and bronchodilator administration on absolute and relative indices of pulmonary function during eupnoeic respiration and carbon dioxide-induced hyperpnoea (rebreathing) in healthy horses using a pneumotachographic spirometry system. Sedation with acetylpromazine (ACP), xylazine, or both drugs in combination was associated with significant reductions in respiratory frequency, minute ventilati...
Kwok KY, Choi TLS, Kwok WH, Wong JKY, Wan TSM.Anabolic and androgenic steroids (AASs) are a class of prohibited substances banned in horseracing at all times. The common approach for controlling the misuse of AASs in equine sports is by detecting the presence of AASs and/or their metabolites in urine and blood samples using gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS). This approach, however, often falls short as the duration of effect for many AASs are longer than their detection time in both urine and blood. As a result, there is a high risk that such AASs could escape detection in the...
Partlow J, David F, Hunt LM, Relave F, Blond L, Pinilla M, Lavoie JP.Small volume pneumothorax can be challenging to diagnose in horses. The current standard method for diagnosis is standing thoracic radiography. We hypothesized that thoracic ultrasonography would be more sensitive. Objectives of this prospective, experimental study were to describe a thoracic ultrasound method for detection of small volume pneumothorax in horses and to compare results of radiography and ultrasound in a sample of horses with induced small volume pneumothorax. Six mature healthy horses were recruited for this study. For each horse, five 50 ml air boluses were sequentially introd...
Freeland RB, Morello SL, DeLombaert M, Rajamanickam V.To quantify the influence of intravenous regional limb perfusion (IVRLP) with amikacin on bacterial bioburden in limb wounds. Methods: In vivo, experimental. Methods: Four adult horses. Methods: Full thickness wounds created on each dorsal metacarpus were inoculated with Staphylococcus aureus. One forelimb was randomly assigned to cephalic vein IVRLP with amikacin on days 2, 3, and 4 post-wounding. Biopsies on day 2 prior to IVRLP, and on days 5 and 8 were cultured to quantify wound bioburden (CFU/g). Two horses repeated the study in a crossover design, receiving IVRLP on the opposite limb (nâ...
Bracamonte JL, Thomas KL.To document laparoscopic cryptorchidectomy with a vessel-sealing device in dorsal recumbent horses. Methods: Retrospective study. Methods: Forty-three male horses. Methods: Food was withheld for 36 hours before horses were placed under general anesthesia and positioned in dorsal recumbency. One laparoscopic portal and 2 instrument portals were placed for the laparoscopic procedure. A third instrument portal was created in bilateral cryptorchid horses. A vessel-sealing device was used for hemostasis and transection of retained testes. Descended testes were removed via closed castration with pri...
Seabaugh KA, Selberg KT, Mueller POE, Eggleston RB, Peroni JF, Claunch KM, Markwell HJ, Baxter GM.Osteoarthritis (OA) of the centrodistal (CD) and tarsometatarsal (TMT) joints is a common cause of lameness in horses. Intra-articular diagnostic anaesthesia and/or therapeutic injection are relied upon to help diagnose and treat many horses with OA of these joints. Objective: The objective of this study was to determine the accuracy of arthrocentesis of the CD and TMT joints using a sample population of equine surgeons and surgery residents. Methods: Randomised experimental study. Methods: Six operators each injected four CD and four TMT joints in 12 sedated horses. The operators were randoml...
Nottrott K, De Guio C, Khairoun A, Schramme M.Navicular disease in the horse often requires injection of the navicular bursa. We have developed an ultrasound-guided, lateral needle approach to navicular bursocentesis, which avoids penetration of the deep digital flexor tendon (DDFT) and the need for radiographic control. Objective: To describe and evaluate the feasibility and efficacy of an ultrasound-guided, lateral bursocentesis technique. Methods: Cadaveric and in vivo experiments. Methods: The navicular bursa in 62 cadaveric forelimbs of 31 horses and in both forelimbs of 26 live horses, positioned with the foot flexed in a navicular ...
Colbath AC, Hackett ES, Lesser CS, Hendrickson DA.To develop a novel technique for left paralumbar laparoscopic bilateral ovariectomy in standing, sedated mares. Methods: Prospective descriptive clinical study. Methods: Twelve client-owned mares. Methods: Healthy mares with normal ovarian palpation and ultrasonographic appearance were enrolled. Horses were restrained in standing stocks and administered a variable rate infusion of sedation. A left paralumbar bilateral ovariectomy was performed with 1 laparoscopic and 3 instrument portals. Access to the right ovary was facilitated by retracting the descending colon and associated mesentery with...
Kelmer G, Tatz AJ, Kdoshim E, Britzi M, Segev G.This prospective experimental study goal was to determine the pharmacokinetics of imipenem after intravenous regional limb perfusion (IV-RLP) in standing horses. Nine horses participated in the study; that was approved by the University Animal Care and Use Committee. One thoracic limb or one pelvic limb of each horse was randomly selected. After the veins were catheterized, an Esmarch bandage tourniquet was applied and the catheter was injected with a solution containing 500mg of imipenem. Synovial fluid samples were collected from the fetlock joint and blood samples were collected from the ju...
Chan J, Doyle B, Branley J, Sheppeard V, Gabor M, Viney K, Quinn H, Janover O, McCready M, Heller J.In November 2014, New South Wales Health was notified of a cluster of respiratory illness in a veterinary school. Active case finding identified another case at a local equine stud. All cases had exposure to the equine fetal membranes of Mare A. This tissue subsequently tested positive for Chlamydia psittaci using quantitative real-time polymerase chain reaction. We conducted a cohort study of the university and stud farm staff to determine risk factors for disease. Nine people were exposed to the fetal membranes of Mare A. Of these, five cases of psittacosis were identified. Two required hosp...
Cruz Benedetti IC, Nottrott K, Fourel I, Le Bris M, Mongellas E, Portier K.To compare the effects of a lidocaine constant rate infusion (CRI) combined with 1% isoflurane versus those of 2% isoflurane alone on cardiovascular variables in anaesthetized horses, and to estimate the sample size required to detect a difference in recovery quality. Methods: Prospective, randomized, blinded, crossover study. Methods: Twelve healthy experimental horses. Methods: Horses were anaesthetized twice using an intravenous (IV) administration of acepromazine, romifidine, diazepam and ketamine. Horses were placed in dorsal recumbency and ventilated mechanically. During the first 10 min...
Arcaro I, Fischer BL, Lascola KM, Clark-Price SC.To investigate the effects of intravenous (IV) administration of terbutaline on PaO, PaCO, pH, heart rate (HR) and arterial pressures in healthy, laterally recumbent horses breathing ambient air under total intravenous anesthesia (TIVA). Methods: Prospective experimental study. Methods: Eight healthy adult horses were enrolled. Six horses, four mares and two geldings weighing 433-624 kg, completed the study. Methods: Horses were sedated with xylazine (1.0 mg kg) IV for placement of arterial and venous catheters. Anesthesia was induced with midazolam (0.1 mg kg) and ketamine (2.2 mg kg) IV and ...
Mosing M, Marly-Voquer C, MacFarlane P, Bardell D, Böhm SH, Bettschart-Wolfensberger R, Waldmann AD.To evaluate the regional distribution of ventilation in horses during spontaneous breathing and controlled mechanical ventilation (CMV) using electrical impedance tomography (EIT). Methods: Prospective, experimental case series. Methods: Four anaesthetized experimental horses. Methods: Horses were anaesthetized with isoflurane in an oxygen-air mixture and medetomidine continuous rate infusion, placed in dorsal recumbency with an EIT belt around the thorax, and allowed to breathe spontaneously until PaCO reached 13.3 kPa (100 mmHg), when volume CMV was started. For each horse, the EIT signal wa...
Coutu P, Caulkett N, Pang D, Boysen S.Hypoxemia is common during equine field anesthesia. Our hypothesis was that oxygen therapy from a portable oxygen concentrator would increase PaO2 during field anesthesia compared with the breathing of ambient air. Methods: Prospective clinical study. Methods: Fifteen yearling (250 - 400Â kg) horses during field castration. Methods: Horses were maintained in dorsal recumbency during anesthesia with an intravenous infusion of 2000Â mg ketamine and 500Â mg xylazine in 1Â L of 5% guaifenesin. Arterial samples for blood gas analysis were collected immediately post-induction (PI), and at 15 and 30Â...
Curran S, Ginther OJ.Embryonic heart rate was studied during 87 examinations in 56 mares on Days 25 to 174 post ovulation. Real-time B-mode using a stopwatch and M-mode ultrasonography were compared. For analyses of heart rates, data were grouped into weeks or months. For the stopwatch and M-mode techniques, respectively, heart rates averaged 123 and 133 beats per minute during Month 1, peaked during Month 3 at 172 or 196 beats, then gradually decreased over the duration of the study to 126 and 130 beats during Month 6. There was a significant increase in heart rate from Months 1 to 2 and Months 2 to 3 and a signi...
Stein FJ, Geller SC, Carter JC.To determine whether microchips used for identification migrate after implantation in horses, donkeys, and mules. Methods: Prospective study. Methods: 53 horses, donkeys, and mules. Methods: Twenty horses that had had microchips implanted in the nuchal ligament at a veterinary teaching hospital from 1996 through early 2000 were included (group 1), and the poll-to-withers distance and location of the microchip were determined, measured, and recorded. Additionally, the poll-to-withers distance was measured in 16 horses, 12 donkeys, and 5 mules (group 2), and microchips were implanted in the nuch...
Pfau T, Starke SD, Tröster S, Roepstorff L.Pelvic movement is altered in hind limb lame horses. A simple method using one inertial measurement unit (IMU) attached to the sacrum, which objectively measures 'hip hike', will help detecting hind limb lameness in large scale studies. In this study, IMUs over the sacrum and the left and right tuber coxae (TC) quantified vertical movement symmetry (MS) in 10 clinically lame horses. A simple geometrical model was used to estimate TC movement from the sacrum IMU. The differences between measured and estimated MS values (mean±SD) and MS changes during different exercise conditions (straight, ci...
Walesby HA, Ragle CA, Booth LC.A 12-year-old stallion was evaluated because of pollakiuria; endoscopy of the urinary tract during general anesthesia revealed that the urinary bladder was intact. After recovery, the stallion developed clinical and biochemical signs of bladder rupture, which was confirmed by endoscopy. Cystoplasty in adult stallions represents a unique surgical dilemma; the large distance between the incision site and the bladder necessitates the repair be accomplished under maximum tension with minimal exposure. Because traditional surgical approaches through ventral midline or paramedian incisions provide l...
Kotoyori Y, Yokoo N, Ito K, Murase H, Sato F, Korosue K, Nambo Y.The objective was to assess the optimal procedure for real-time, three-dimensional (3D) ultrasound (US) imaging for assessing the equine fetus during the first half of gestation and the possibility of using 3D US imaging of the equine fetus in clinical applications. Seventeen pregnant mares were examined by 3D US between Days 35 and 180 of gestation. Abdominal and endo-vaginal real-time 3D transducers used in human medicine were used for transrectal and transvaginal examinations, respectively. Images were recorded by both 3D stationary and real-time movies. In a comparison of four methods, tra...
Pierce RL, Fischer AT, Rohrbach BW, Klohnen A.To compare incidence of postoperative complications and survival of horses that had surgery for enterolithiasis of the ascending (AC) or descending (DC) colon. Methods: Case series Methods: Horses (n=236) that had celiotomy for AC (n=97) or DC (n=139) enterolithiasis. Methods: Medical records (1999-2005) were reviewed for signalment, presenting clinical signs, surgical findings, postoperative complications, and short-term survival until discharge. Information on performance and survival > or = 1 year was obtained by telephone or mailed questionnaire. Results: Number of postoperative complicati...
Westendorf J, Wobeser B, Epp T.The Kenney-Doig scale is a histopathology categorization (grading) system often used as the standard for assessing endometrial disease and communicating prognostic fertility information for equine breeding prospects. We investigated how Kenney-Doig categories compared within the same institution and across different institutions to determine if observer variability may contribute to category frequencies. We conducted a retrospective analysis of all equine endometrial submission records between 1998 and 2018 at the Western College of Veterinary Medicine (WCVM) and Prairie Diagnostic Services (P...
Rashid A, Mubarak A, Hussain A.Equine babesiosis is a tick-borne haematological disease of equidae that can affect acutely, subacutely and chronically. The disease is manifested by intermittent fever, anaemia, icterus and haemoglobinuria. The authors describe the clinical, haematological and therapeutic aspects of babesiosis in equines at two units in Kotley and at two units in Jehlum of the Remount Veterinary and Farms Corps (RVFC). Animals on these units showed the signs of illness. On clinical examination, intermittent temperature, increased respiratory rate, anaemia, lacrimation, conjunctivitis and pale mucous membranes...
Vernemmen I, Paulussen E, Dauvillier J, Decloedt A, van Loon G.This case report describes the 2-dimensional transthoracic (2D-TTE), 3-dimensional transthoracic (3D-TTE) and intracardiac echocardiographic (ICE) characterization of the fossa ovalis region in 2 horses. The first case was presented for poor performance and showed an anechoic zone in the interatrial septum on 2D-TTE. Based on 3D-TTE a deepened fossa ovalis could be identified and using ICE the presence of an interatrial shunt could be excluded. The second case was referred for a cardiac murmur and the presence of turbulent flow in and around the interatrial septum on 2D-TTE color flow Doppler....
Magdesian KG.Measurements of physiologic parameters, such as blood pressure or lactate concentration, are useful to detect occult derangements, such as tissue hypoxia and dysoxia. These tools are also useful in determining the effects of therapy. Monitoring techniques are now widely available for the intensive management of critically ill horses and foals. A number of these have evolved into noninvasive or minimally invasive devices and procedures and provide information that can be used for earlier and more dynamic therapeutic intervention. The goal of increased monitoring is to improve the level of care ...
Vachon AM, Fischer AT.Thirty-two thoracoscopies were performed in 28 horses. Sixteen horses were affected with pleuropneumonia whereas 12 were affected with various other thoracic conditions. The indications for thoracoscopy was diagnostic in 19 cases, therapeutic in 11 cases and both diagnostic and therapeutic in 2 cases. Twenty-six thoracoscopies were done standing whereas 6 were performed under general anaesthesia. The specific procedures performed during thoracoscopy were exploratory only (7), biopsy of the lung and lymph nodes (10), drain placement into pleural effusions (2) and abscesses (5), exploration prio...
Geburek F, Rötting AK, Stadler PM.To assess agreement between ultrasonography (transcutaneous and transrectal) and standing radiography in horses with fractures in the pelvic region and disorders of the coxofemoral joint. Methods: Case series. Methods: Warmblood horses (n=23) and 2 ponies. Methods: Medical records (1999-2008) of equids with pelvic or coxofemoral disorders that had pelvic radiography and ultrasonography were retrieved and results of both techniques compared. Results: Radiography and ultrasonography each identified equal numbers of fractures of the tuber coxa (n=4), ilial shaft (2), ischium (3), femoral neck (2)...
Decloedt A, de Clercq D, Ven S, van der Vekens N, Chiers K, van Loon G.Endomyocardial biopsies could be a valuable tool in equine cardiology for diagnosing myocardial disease, which is probably underdiagnosed in horses because of lack of specific diagnostic measures and limitations of currently available diagnostic methods. Objective: To describe a technique for serial right atrial and right ventricular endomyocardial biopsy in standing horses using a percutaneous approach through the jugular vein. Methods: Prospective study. Methods: Biopsy was performed in 10 healthy standing horses sedated with detomidine, under continuous electrocardiography monitoring. A 10 ...
Fischer B, Clark-Price S.Anesthetizing the neonatal foal presents significant challenges as a result of physiologic differences from the adult equine. This article gives the reader an overview of these differences and the impact they have on anesthetic drug selection, monitoring, and support of the equine neonate. Special emphasis is directed to the sick neonate and appropriate preparation and maintenance of anesthesia in the face of commonly presented disease conditions.
Broux B, De Clercq D, Decloedt A, Van Der Vekens N, Verheyen T, Ven S, Pardon B, van Loon G.The electrocardiographic differentiation between atrial (APDs) and ventricular (VPDs) premature depolarizations is important. P wave prematurity and normal QRS and T wave morphology generally are used as discriminating criteria for APDs. Objective: The aim of this study was to determine whether P, Q, R, S, and T wave amplitude, PQ interval, QRS and P wave duration and P and T wave morphology differ between APDs and sinus beats. To determine the relationship between the RR coupling interval and the change in S wave amplitude between sinus beats and APDs. Methods: Case-control study. From a modi...
Annear MJ, Wilkie DA, Gemensky-Metzler AJ.To evaluate the outcome of diode laser transscleral cyclophotocoagulation (TSCP) for the treatment of glaucoma in horses. Methods: Medical records at The Ohio State University were reviewed. All horses that underwent diode laser TSCP between the years of 1995 and 2007 were included. Preoperative, procedural and clinical follow-up data were collected, and telephone follow-up was performed. Results: Forty-two eyes of 36 horses were included. Twenty-four hours prior to surgery mean intraocular pressure (IOP) was 37.17 + or - 13.48 mmHg (42 eyes). Forty-one of 42 eyes (98%) were sighted and 39 of ...
Driessen B, Scandella M, Zarucco L.To develop a technique for placing continuous peripheral nerve block (CPNB) catheters adjacent to palmar nerves in horses and to evaluate the effect of low-volume local anesthetic (LA) infusion on nociception in the distal equine thoracic limb. Methods: In vitro and in vivo laboratory investigation. STUDY MATERIAL AND ANIMALS: Forty-two thoracic limbs from 22 equine cadavers and five horses. Methods: Thoracic limb specimens were dissected to find landmarks for catheter insertion adjacent to medial and lateral palmar nerves. Based on the anatomy of the proximal metacarpus, a technique for placi...
Venner M, Schmidbauer S, Drommer W, Deegen E.The aim of the study reported here was to compare complications of lung biopsy in horses and the quality of the lung specimens after biopsy using the manual Tru-Cut biopsy needle (TC) and an automated biopsy needle (ABN). For experiment 1, lung biopsy was performed in 50 horses with one instrument on one side of the thorax, and then with the other instrument on the other side. Postmortem examination was performed in 20 of the 50 horses. Coughing was detected in 10 of 50 horses and epistaxis was observed in 6 of the 50 horses. Endoscopy revealed bleeding into the airways in 16 of 49 horses and ...
Marzok MA, El-Khodery SA, Oheida AH.To evaluate the effect of intravenous administration of romifidine on the intraocular pressure (IOP) in horses. Methods: Twenty-four horses with no ocular abnormalities. Methods: Horses were randomly assigned into two equal groups (treatment and control). All horses in the treatment group received an intravenous (IV) injection of romifidine (40 μg/kg). The horses in the control group were administrated an intravenous injection of 0.9% saline (0.4 mL/100 kg). In both groups, the IOP values were measured immediately (T0 ) pre-administration and at 5 (T5 ), 15 (T15 ), 30 (T30 ), 45 (T45 ), 60 (T...
Taylor SE, Barakzai SZ, Dixon P.To evaluate the effect ventriculocordectomy (VC) for treatment of recurrent laryngeal neuropathy (RLN) on exercise performance and owner satisfaction in a mixed-breed population of horses. Methods: Retrospective study. Methods: Adult horses (n=92) with a history of abnormal respiratory noise and RLN. Methods: Retrospective analysis of horse that had unilateral VC (and contralateral ventriculectomy in 63 horses) for treatment of idiopathic RLN. Owners/trainers completed a questionnaire about complications and outcome at least 1 year after surgery. Performance index was determined using race rec...
Shields E, Seiden-Long I, Massie S, Passante S, Leguillette R.Cardiac troponin-I assays have been validated in horses.'High-sensitivity' cardiac troponin assays are now the standard in human cardiology. Objective: Appropriately validate the'high-sensitivity' cardiac Troponin-T (hscTnT) assay for clinical use in horses, establish reference intervals, determine the biological variation, and demonstrate assay utility in selected clinical cases. Methods: Analytical validation of the Roche hscTnT assay included within- and between-run precision, linear dose response, limit of quantitation (LoQ), stability, and comparison with cTn-I (iSTAT). Reference interval...
Goodrich LR.Much has been learned in the past decade about osteomyelitis. The inhibitory mechanisms of the "biofilm slime" layer that is formed by bacterial extracapsular exopolysaccharides and binds to bone, joints, and implants are now better understood than in the past. The surface colonization of bacteria that occurs within these biofilms is a biologic phenomenon that is somewhat unique to orthopedic infections. This survival strategy of bacteria is effective, and it is important for veterinarians who treat osteomyelitis to be aware of current diagnostic and therapeutic treatment modalities. The pract...
Smyth TT, Allen AL, Carmalt JL.To describe histologic changes in the temporomandibular joints (TMJs) of horses of various ages. Methods: 22 TMJs from cadavers of 11 horses. Methods: Horses were categorized into 3 age groups (group 1, 2 to 10 years old [n = 3]; group 2, 11 to 20 years old [3]; and group 3, > 20 years old [5]). Each TMJ was sectioned into 5-mm slices, preserved in formalin, decalcified in formic acid, and routinely processed for histologic analysis. Joints were systematically assessed by use of previously described methods. Multilevel mixed-effects models were used to examine the data. Results: The number of ...
Fielding CL, Brumbaugh GW, Matthews NS, Peck KE, Roussel AJ.To determine the pharmacokinetics and clinical effects of a subanesthetic, continuous rate infusion of ketamine administered to healthy awake horses. Methods: 8 adult horses. Methods: Ketamine hydrochloride was administered to 2 horses, in a pilot study, at rates ranging from 0.4 to 1.6 mg/kg/h for 6 hours to determine an appropriate dose that did not cause adverse effects. Ketamine was then administered to 6 horses for a total of 12 hours (3 horses at 0.4 mg/kg/h for 6 hours followed by 0.8 mg/kg/h for 6 hours and 3 horses at 0.8 mg/kg/h for 6 hours followed by 0.4 mg/kg/h for 6 hours). Conce...
Gastal EL, Kot K, Ginther OJ.A technique for intrafollicular treatment with a transvaginal ultrasound-guided injection needle was developed using equine chorionic gonadotropin (eCG) as the test substance. An injection was made into one growing follicle of a wave when the follicles were 20 to 23 mm. The treated follicles were injected with 1000 iu of eCG in 0.2 ml saline solution and control follicles were injected with 0.2 ml of the saline vehicle (10 mares per group, 1 follicle per mare). The injection system used an inner 25-gauge needle and an outer 20-gauge needle inserted together through the needle-guide channel of ...
Freden GO, Provost PJ, Rand WM.To assess clinical utility of abdominal fluid analysis in predicting outcome, lesion type, and whether medical or surgical treatment is indicated for horses with colic. Methods: Retrospective study. Methods: 218 horses > 1 year old. Methods: Horses were classified on the basis of age, site of lesion, lesion type (nonstrangulating vs strangulating), type of treatment (medical vs surgical), and outcome (survival vs nonsurvival). Sensitivity and specificity of using age and results of abdominal fluid analysis, individually and in combination, to predict lesion type, type of treatment, and outc...
Tennent-Brown BS, Mudge MC, Hardy J, Whelchel DD, Freeman DE, Fischer AT.6 horses were determined to have torsion of a liver lobe at 4 referral institutions over a 21-year period. Results: Clinical findings were nonspecific but often included signs of marked inflammation. Two of the 6 horses were examined because of colic, and 2 were assessed because of peritonitis that failed to respond to treatment; the remaining 2 horses were examined because of nonspecific clinical signs that included inappetence, lethargy, and weight loss. The results of laboratory tests were widely variable, and values for liver enzyme activities were typically within reference limits or only...
Villani M, Romano G.The aim of the present study was to evaluate the clinical applications and limitations of daily low-dose oxytocin injections for the induction of parturition in pregnant at term mares, the attention was focussed on the efficacy of the treatment and on its possible negative effects on mare and foal. Three-hundred and fifty pregnant full term Standardbred mares were used: 176 were allowed to foal spontaneously, 174 were treated daily with 3.5 IU of oxytocin i.m. when mammary secretion showed a calcium concentration >or= 200 ppm. For each mare, gestational length, outcome and duration of foaling,...
Fagliari JJ, McClenahan D, Evanson OA, Weiss DJ.To determine whether plasma protein concentrations were altered in ponies with alimentary laminitis. Methods: 12 adult ponies. Methods: Acute laminitis was induced in 6 ponies by oral administration of carbohydrate (85% corn starch, 15% wood flour); the other 6 ponies were used as controls. A physical examination was performed and blood samples were collected immediately before and 4, 8, 12, 24, and 28 hours after administration of carbohydrate. Plasma protein concentrations were determined by means of sodium dodecyl sulphate-polyacrylamide gel electrophoresis. Results: 19 plasma proteins rang...
