Veterinary research in horses encompasses the study of diseases, health management, and medical treatments specific to equine species. This field investigates various aspects of horse health, including infectious diseases, metabolic disorders, and musculoskeletal conditions. Researchers focus on understanding the pathophysiology of equine ailments, developing diagnostic tools, and evaluating therapeutic interventions. The study of horse health also involves examining preventive measures such as vaccination protocols and nutritional management to promote overall well-being. This page collects peer-reviewed research studies and scholarly articles that explore the diverse areas of veterinary science related to horses, providing insights into disease mechanisms, treatment strategies, and advancements in equine healthcare.
Anderson RS, Day NK, Good RA.Natural hemagglutinin activity against vertebrate erythrocytes is present in the hemolymph of the cockroach Blabarus craniifer. The hemagglutinin titer against rabbit erythrocytes is high, whereas sheep and horse red cells agglutinate weakly. Hemagglutinin activity was depressed by the complement inhibitor, cobra venom factor. Cockroach hemagglutinin is heat-labile; all activity is destroyed by heating at 56 C for 1 hr. A humoral factor similar to the complement component 3 proactivator is also present in cockroach hemolymph. The formation of the cobra venom factor-hemolymph "complex" is depen...
Pereira HG, Takimoto S, Piegas NS, do Valle LA.Influenza equine (Heq2Neq2) strains isolated during the course of epizootics observed in Guanabara (Rio de Janeiro) and São Paulo, Brazil, in July-October 1969 were shown to differ antigenically from earlier strains of the same subtype (A/equine/Miami/1/63 (Heq2Neq2)). The difference could be clearly demonstrated in haemagglutination inhibition tests performed with postinfection horse or ferret sera but not with hyperimmune rooster sera. Antibody responses of diseased horses were higher and more frequent against current isolates than against strain equine/Miami/1/63. Some animals also showed ...
Sundra T, Gough S, Rossi G, Kelty E, Rendle D.Oral omeprazole is the accepted treatment for equine squamous gastric disease (ESGD); however, it is not universally effective. Esomeprazole results in more consistent and pronounced acid suppression in men and is more effective than omeprazole in the treatment of oesophageal and gastric disease. Pharmacodynamic and pilot clinical studies have indicated esomeprazole might also be more effective than omeprazole in horses. Objective: To compare the efficacy and safety of oral esomeprazole and omeprazole pastes in the treatment of ESGD and, where present, concurrent equine glandular gastric disea...
Hudgens E, Tompkins D, Boyd P, Lunney JK, Horohov D, Baldwin CL.This report describes the cloning and characterization of expressed gene sequences of bovine, equine, and swine CXCL9 from RNA obtained from peripheral blood mononuclear cells (PBMC) and other tissues. The bovine coding region was 378 nucleotides in length, while the equine and swine coding regions were 381 nucleotides. Mapping showed that all three sequences were coded for in four exons in the genome, as are the human and mouse genes. The bovine, equine, and swine coding regions shared 83%, 86%, and 84% homology with human CXCL9, respectively, and all three were 74% homologous with mouse CXCL...
Norton NM, Santschi E, Fischer KJ.The etiology of subchondral bone cysts (SBCs) is not fully understood. Mechanical trauma and fluid pressure are two mechanisms believed to cause their formation and growth. The equine stifle joint provides a natural animal model for studying SBCs. Computed tomography images of an extended yearling cadaveric stifle joint were segmented using ScanIP to isolate bones and relevant soft tissues. Three model geometries were created to simulate cyst sizes of approximately 0.03 cm (C1), 0.5 cm (C2), and 1 cm (C3). A uniform pressure resulting in 3000 N force was applied at the proximal end of the fem...
Tekin N, Yurdaydin N, Klug E, Yavas Y, Aksu A, Gülyüz F.Within a German-Turkish university partnership documentation of reproductive data of brood-mares was performed as a part project of the cooperation contract. In the study Arab, Haflinger and cross-breed mares were included. The mares mainly were housed in big studfarms and a smaller part was kept under small private farms. Almost three quarters of both the Arab and Haflinger mares exhibited an estrous length of 1-4 days, whereas the others showed a heat duration of a period of 5-10 days. In the same group of probands a mean length of sexual cycle of 18-24 days could be observed in 38.2% of the...
Fousse SL, Stern JA.There have been some advances in understanding the genetic contribution to ventricular septal defects in Arabians, sudden death in racehorses, and atrial fibrillation in racehorses. No genetic analyses have been published for aortic rupture in Friesians or atrioventricular block in donkeys despite strong evidence for a genetic cause. To date, no genetic mutation has been identified for any equid cardiac disease. With the advancement of genetic tools and resources, we are moving closer to discoveries that may explain the heritable basis of inherited equid cardiac disease.
Zorin NA, Rykov VA, Potekhin VK, Savinykh VI, Chirikova TS.Using disc-electrophoresis in polyacrylamide gel and immunochemical methods, studies have been made on proteins from the vitreous body of mammals (albino mouse, rat, guinea pig, pig, dog, cat), birds (hen), amphibians (the frog Rana ridibunda) and fish (the perch Perca fluviatilis). It was found that vitreous body proteins in man and animals include both the specific proteins and those of the blood serum. During evolution, specific antigens of the vitreous body attained strict species specificity, although some of them preserved the initial properties.
Baskerville A.For laboratory diagnosis of respiratory disease it is of overwhelming importance that the specimens taken are adequate, taken from the correct site and at the correct time. The lower regions of the respiratory tract are particularly difficult to sample but are more likely to yield the causative agent of a pneumonia. Infections involving the upper respiratory tract are much easier to sample and appropriate aspiration apparatus can be used. Consideration must be given to the timing of sample collection in relation to the life cycle of the causative micro-organism. Sampling of several animals is ...
Journée SL, de Ruijter-Villani M, Hendriks WK, Stout TA.Transvaginal ultrasound-guided pregnancy reduction (TUGR) is a procedure described for the management of twins post-fixation in the horse. Success rates are often disappointing but are reported to be more favorable for bilaterally situated twins and when intervention takes place before day 35 of gestation. This study aimed to determine whether stabbing the embryo/fetus rather than aspirating conceptus fluids improved the likelihood of success, measured as the birth of a normal live singleton foal. Data from 103 TUGR interventions were analyzed by logistic regression analysis; method of treatme...
Nemoto M, Okita N, Kitahata M, Bannai H, Tsujimura K, Kinoshita Y, Kambayashi Y, Cullinane A, Yamanaka T, Ohta M.A rapid and sensitive diagnostic method is needed to help prevent the spread of equine influenza virus. The cobas Influenza A/B & RSV test for the cobas Liat system (Roche Diagnostics) is based on real-time reverse transcription polymerase chain reaction and is designed to broadly detect influenza A virus RNA within 20 minutes. It detected a broad range of equine influenza virus strains, and detected equine influenza virus RNA from nasal swabs of infected horses at the same level as real-time reverse transcription polymerase chain reaction, although it returned some invalid results (7.7%)...
Pomelova VG, Gaĭdamovich SIa, Demenev VA, Kadoshnikov IuP.A three-step concentration of Venezuelan equine encephalomyelitis (VEE) virus from tissue culture fluid was carried out in a two-phase system of polyethyleneglycol (PEG)--sodium dextran sulphate (SDS). The concentration method was based on the dependence of virus distribution coefficient upon NaCl content in the system which allowed alternating transfer of the virus from one phase of the system into the other. The infectious activity of the virus increased approximately 100-fold after the first step, 190-fold after the second, and 300-fold after the third step. The process of concentration was...
Giusto G, Cerullo A, Gandini M.Transillumination has been described in human surgery to improve vessel visualization but has not been described in horses. Since the equine mesocolon contains a great amount of fat which restricts visualization of the vessels, this technique could be useful during small colon resection. To describe transillumination of the mesocolon to provide an improved vessel identification during resection and anastomosis of the small colon in horses. Data of horses that underwent resection and anastomosis of small colon were recorded. Two transillumination techniques were used during resection and anasto...
Zarrilli A, Lacalandra GM, Minoia P.In mare, sheep and bitch the action of PGF2 alpha have been studied in the early pregnancy. Prostin F2 alpha (Upjohn) and Gabbrostim (Vetem ) are commercial names of PGF2 alpha used at doses which are luteolytic in the non pregnant female. Seric progesterone showed a temporaneous decrease but after four or five days the initial values were restored and none of the experimental females aborted. In the opinion of authors, embryo per se and/or with its adnexa might have interacted blocking the mechanism of luteolysis induced by the administration of PGF2 alpha.
