Veterinary research in horses encompasses the study of diseases, health management, and medical treatments specific to equine species. This field investigates various aspects of horse health, including infectious diseases, metabolic disorders, and musculoskeletal conditions. Researchers focus on understanding the pathophysiology of equine ailments, developing diagnostic tools, and evaluating therapeutic interventions. The study of horse health also involves examining preventive measures such as vaccination protocols and nutritional management to promote overall well-being. This page collects peer-reviewed research studies and scholarly articles that explore the diverse areas of veterinary science related to horses, providing insights into disease mechanisms, treatment strategies, and advancements in equine healthcare.
Rossdale PD.Diagnosis in veterinary medicine is based upon observations of the manner in which the behavioural patterns differ from those exhibited by normal subjects. The newborn foal adapts to an advanced level of activity within a period which is short relative to many other species, and the behavioural patterns which it exhibits during the period of adaptation are comparatively stereotyped. Because the status of any newborn mammal is affected by its previous experience of foetal development and birth, the behavioural patterns of the mother form an important anamnesis in the life of each individual neo...
Williams MA, Harrison PM.Horse ferritin was fractionated both by starch-gel electrophoresis and by gel filtration on Sephadex G-200. Monomer fractions contained up to 98% of monomer and oligomer fractions up to 76% of oligomers as determined by quantitative electron microscopy. Percentages obtained from electron micrographs correlated well with analytical starch-gel electrophoretograms and ultracentrifuge patterns. Amino acid analyses of monomer- and oligomer-enriched fractions showed no significant differences. Ferritin oligomers did not apparently dissociate on dilution for electron microscopy or on storage. Apoferr...
Page AE, Wood C, Partridge E, Horohov DW, Adam E.The use of lipopolysaccharide to induce a localized source of inflammation (acute synovitis) and allow for monitoring of changes in systemic mRNA expression has been recently reported. Here, the goal was to maintain a significant systemic mRNA response while limiting the severity of lameness such that this model can be used to examine the effects of various anti-inflammatory treatment modalities on mRNA expression. Three mixed breeds, four-year-old geldings were utilized for this study. One milliliter of phosphate-buffered saline containing 1,000 ng or less of lipopolysaccharide from E. coli O...
Thomas KL, Carmalt JL, Burnett WD, Arjmand H, Johnston JD.OBJECTIVE To compare strain at the bone-pin and cast-pin interfaces among 3 transfixation pin-cast constructs applied to equine forelimbs. ANIMALS 15 forelimbs from 15 adult horses. PROCEDURES Limbs were randomly assigned to 1 of 3 constructs. Centrally threaded positive-profile pins were used for all constructs, and the most distal pin was placed just proximal to the epicondyles of the third metacarpal bone. Construct 1 consisted of two 6.3-mm-diameter pins spaced 4 cm apart at 30° to each other. Construct 2 was the same as construct 1 except the pins were placed 5 cm apart. Construct 3 cons...
Dyson DA, Smith GR.When incorporated in solid medium at a concentration of 15 per cent, the defibrinated blood of certain horses strongly suppressed the growth of some, but not all, strains of Mycoplasma mycoides subsp mycoides so that many colonies failed to develop to a visible size. Blood from a single rabbit was tested and found to exert a similar effect. There was striking variation in the degree of inhibition produced by different samples of horse blood and, of five strains of the organism examined, the T1 vaccine strain was the most susceptible. The results suggested that the effect was not due to antibod...
Bergman HJ, de Kruif A, van Dessel S.In this article different possible treatments for problem mares are discussed. The therapeutic possibilities vary and can be classified into anatomical correction, anti-infectious therapy, and treatment to enhance the uterine defence mechanisms. Anatomical correction and treatment with antibiotics are valuable therapies and have been used for many years. In recent years, stimulation of the mechanical defence mechanism of the uterus, by flushing it with physiological solution combined with parenteral oxytocin, has been shown to increase the chance of getting problem mares in foal.
Tatarov G, Martinov S, Panova M.It was established that the complement binding reaction (CBR) is a suitable and very fast method for horse rhino-pneumonitis diagnostics. Cell cultural virus produced in cell cultures of pig kidneys was used as antigen. The antigen lots tested have no anticomplementary properties. Highest complement binding activity was evident in the non-diluted antigen, which discovered specific antibodies in immune serums. The CBR specificity was tested by the aid of homologous and heterologous serums and antigens. The titers of complement binding antibodies in the serums of 255 horses recovered from the di...
Ludewig T.Glomus organs (Hoyer-Grosser's organs) were frequently found in the corium and the subcutis of the skin of the equine and bovine mammary gland. They were most frequently situated in the border zone between the stratum profundum and the stratum superficiale corii. These specialized vascular structures (arterio-venous anastomosis) were present in all investigated skin areas. Although the glomus organs varied in size and shape, they possessed common histologic structures: an arteriole entered the connective capsule of the glomus and divided into strongly convoluted arterio-venous channels; the ar...
Lyons ET, Tolliver SC, Drudge JH, Swerczek TW, Crowe MW.From Mar 1, 1984, to Feb 28, 1985, both eyes from 189 one- to four-year-old Thoroughbreds (88 males, 90 females, and 11 geldings) in Kentucky were examined at necropsy for eyeworms. Thelazia lacrymalis was recovered from 45% of 1-year-old horses, 26% of 2-year-old horses, 45% of 3-year-old horses, and 50% of 4-year-old horses; overall, 43% of 1- to 4-year old horses were infected. Prevalence of eyeworms in horses in the present study was comparable with that in horses of similar ages examined at necropsy in Kentucky in 2 previous studies (1975 to 1976 and in 1979), except for the lower percent...
Liberatori J, Morisio Guidetti L, Conti A.By double diffusion in agarose gel, in well defined experimental conditions, cross reactions were observed between porcine beta-lactoglobulins and anti-bovine beta-lactoglobulin antisera. The immunological reactivity between these beta-lactoglobulins from a monogastric and the ruminant anti beta-lactoglobulin antiserum thus implies a certain degree of similarity between the monomeric beta-lactoglobulins examined and the dimeric of the ruminants. With the same antisera it also proved possible to demonstrate the presence of beta-lactoglobulins in the mammary secretions of another monogastric, na...
Barakzai SZ, Kane-Smyth J, Lowles J, Townsend N.To examine 2 rostral maxillary sinus (RMS) trephine sites for safety and efficacy using skulls of horses of varying age. Methods: Descriptive study. Methods: Cadaveric equine skulls (n=40). Methods: Two RMS trephination sites (rostral, caudal) were made in each skull. Radiographic projections using markers at each site were used to determine if sites were within the RMS and directly overlying a cheek tooth. Sinusotomy in 14 skulls was used to determine correlation between radiographic and anatomic location of trephine sites, and of the rostrolateral aspect of the maxillary septum. Age-related ...
McKinney AR, Suann CJ, Stenhouse AM.An investigation was conducted into the stereochemistry of the equine urinary metabolites of 17alpha-methyltestosterone observed after oral administration. Standards of the complete range of C3/C5/C16 stereoisomeric 17alpha-methylandrostane-3,17beta-diols, 17alpha-methylandrostane-3,16,17beta-triols and 17alpha-hydroxymethylandrostane-3,17beta-diols were purchased or synthesised, and were used to unequivocally identify the absolute structures of the metabolites. Phase I metabolism was found to involve combinations of Delta(4)-3-ketone reduction with both 5alpha,3beta- and 5beta,3alpha-stereoch...
Hough VA, Wycislo KL, Hofmeister EH, Piech TL, Maki LC, Shaver SL.Veterinary students' accuracy, confidence, and time required to diagnose bacterial sepsis in fluid cytology samples was evaluated using two different slide preparation methods: direct smears and cytocentrifuged concentrated preparations. We hypothesized veterinary students would diagnose fluids as septic on concentrated preparations more accurately and quickly than on direct smears. Thirty third- and fourth-year students who had previously participated in a clinical pathology course completed a survey regarding general cytology experience and reviewed 40 randomized Romanowsky-stained slides vi...