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Topic:Veterinary Research
Veterinary research in horses encompasses the study of diseases, health management, and medical treatments specific to equine species. This field investigates various aspects of horse health, including infectious diseases, metabolic disorders, and musculoskeletal conditions. Researchers focus on understanding the pathophysiology of equine ailments, developing diagnostic tools, and evaluating therapeutic interventions. The study of horse health also involves examining preventive measures such as vaccination protocols and nutritional management to promote overall well-being. This page collects peer-reviewed research studies and scholarly articles that explore the diverse areas of veterinary science related to horses, providing insights into disease mechanisms, treatment strategies, and advancements in equine healthcare.
Evaluation of upper respiratory tract function during strenuous exercise in racehorses. Forty-six racehorses with a history of poor performance underwent endoscopic evaluation of laryngeal and pharyngeal function while exercising on a high-speed treadmill. This evaluation allowed the definitive diagnosis of intermittent or continual upper respiratory tract obstruction as a cause of poor performance, as well as the documentation of the dynamic functional anatomy of the obstruction. Ten of the horses (22%) were determined to have a functional abnormality of the upper respiratory tract. These abnormalities included epiglottic entrapment (1 horse), persistent dorsal displacement of t...
Amino acids in different layers of the matrix of the normal equine hoof. Possible importance of the amino acid pattern for research on laminitis. A method was developed for separating different layers of the matrix of the equine hoof wall by dissection, and the layers were then analyzed with respect to their amino acid composition. The results were used to compare the biochemistry of hard keratinization (e.g., in the hoof wall matrix) and soft keratinization (e.g., in the epidermis of the skin). Hard keratinization differed from soft keratinization not only by its previously well known high incorporation of cystine, but also by considerable incorporation of tyrosine and threonine into the outer layers of the keratogenous zone and by the...
Immunogenicity and allergenicity of Culicoides imicola (Diptera: Ceratopogonidae) extracts. Summer seasonal recurrent dermatitis (SSRD) or "sweet itch" is a seasonally occurring allergic dermatitis of horses provoked by biting midges. The allergic skin reactions have been attributed to allergens present in various Culicoides species. C. imicola is the suspected etiological agent of SSRD in Israel. Whole body extracts of this midge induced hypersensitivity reactions upon injection into susceptible horses and in this study attempts were made to define components of C. imicola which have immunogenic and allergenic properties. Immunogenic potency was evaluated by raising antisera to whol...
Is there a morning-evening difference in egg production of bloodworms, strongyle parasites of equines? To test a claim that counts of the eggs of large strongyles or bloodworms, parasites of equines, are greater in morning fecal samples than in those from later in the day, and therefore, may be indicators of circadian variations in these worms, samples from one pony and nine horses were analyzed for strongyle eggs. Samples were collected twice per day, about 7:30 and again about 19:30, during two, 24-day periods. Individual counts varied from 0 to 1184. The mean of all 7:30 counts was 212.52; that of 19:30 counts was 236.03. The difference is not significant, and does not support the idea of ci...
In vivo regulation of plasma [H+] in ponies during acute changes in PCO2. The major objective of this study was to test the hypothesis that in ponies the change in plasma [H+] resulting from a change in PCO2 (delta H+/delta PCO2) is less under acute in vivo conditions than under in vitro conditions. Elevation of inspired CO2 and lowering of inspired O2 (causing hyperventilation) were used to respectively increase and decrease arterial PCO2 (Paco2) by 5-8 Torr from normal. Arterial and mixed venous blood were simultaneously sampled in 12 ponies during eucapnia and 5-60 min after Paco2 had changed. In vitro data were obtained by equilibrating blood in a tonometer at f...
Correction for skin displacement errors in movement analysis of the horse. In movement analysis of the horse, large errors result from movements of the skin with respect to the underlying bones. A generally applicable, two-dimensional, method for correction of these skin-movement errors in kinematic data has been developed. It was tested on a kinematic analysis of the hindlimb in a walking pony. The results indicate that without correction for skin-movement errors, misreadings of up to 15 degrees in the knee angle and 30% in the moment arm of the gastrocnemius muscle can be expected.
Veterinary use of ivermectin. Following the development of a unique claim structure encompassing both nematode and arthropod species, ivermectin was first introduced as a veterinary parasiticide in 1981. For cattle(c), sheep(s), horses(h) and pigs(p) injectable(c,s,p), oral(c,s,h) and topical(c) products are available delivering ivermectin at 200 to 500 micrograms/kg. Efficacy extends to nematodes of the gastrointestinal and respiratory tracts, conjunctival sac and soft tissues. Among the arthropod parasites claims have been established for the biting fly Haematobia irritans(c), the screw-worm Chrysomyia bezziana(c), larva...
Effect of palosein (superoxide dismutase) and catalase upon oxygen derived free radical induced degradation of equine synovial fluid. The effect of oxygen derived free radicals (ODFR) upon the specific viscosity of equine synovial fluid was studied. ODFR were generated either by a mixture of ferrous iron and EDTA (Fe/EDTA) or by a mixture of hypoxanthine and xanthine oxidase (HX/XO). Incubation of the synovial fluid with both free radical generating systems decreased its specific viscosity. When the synovial fluid was incubated with Fe/EDTA the specific viscosity of the synovial fluid was reduced rapidly. By 2 mins, it was 53 +/- 3 per cent of the original specific viscosity and by 30 mins it was reduced to 39 +/- 5 per cent...
Strength characteristics and failure modes of locking-loop and three-loop pulley suture patterns in equine tendons. Size 3-0 polydioxanone was used as a single strand, single braid (3 strands), or double braid (6 strands) to create six suture material-pattern combinations for equine tenorrhaphy: single-strand locking loop, single-braid locking loop, double-braid locking loop, single-strand three-loop pulley, single-braid three-loop pulley, and double-braid three-loop pulley. Maximum load to failure for the single-strand locking loop (46.1 +/- 2.9 newtons [N]) was less than for all other sutures (range, 103-155 N). The load required to form a 2 mm gap between tendon ends was greater for the single-braid thre...
“Synaptic” ribbons in the pineal gland of the horse. Previous studies on the ultrastructure of the horse pineal gland did not report the presence of "synaptic" ribbons, functionally enigmatic pinealocyte organelles regularly occurring in other mammalian species. The aim of the present study was to reinvestigate the horse pinealocyte in this respect. Careful investigations here reported allowed detection of "synaptic" ribbons in the pinealocytes of all the examined animals, although in a relatively low number (5.4 +/- 2.0 per 20,000 microns 2 of pineal tissue; mean +/- SD). The ultrastructure of "synaptic" ribbons in pinealocytes of the horse res...
Prolonged effect of a single injection of human chorionic gonadotrophin on plasma testosterone and oestrone sulphate concentrations in mature stallions. The long term effect of a single injection of 6,000 iu of human chorionic gonadotrophin (hCG) was studied in two pony stallions. Peripheral plasma samples were analysed for testosterone and oestrone sulphate. Testosterone concentrations were markedly elevated for five days after injection in both stallions. No adverse effects of these high concentrations were observed on concentrations later in the experiment. There was an initial increase in oestrone sulphate in one stallion, after which concentrations decreased to below pre-injection levels. The other stallion (whose initial oestrone sulphat...
[New types of virus infections of domestic animals in the German Democratic Republic. 1. Serologic survey studies of the distribution of equine torovirus infections in the GDR]. Sera collected from 124 horses were checked by means of the serum neutralisation test against equine Bern virus. Torovirusspecific antibodies were recordable from 35 percent of all horses tested. These results are likely to suggest that toroviruses are widespread in the GDR and occur not only in horses but in other domestic animals and in man, as well.
Isolation of Clostridium perfringens from foals. Clostridium perfingens was isolated from four of 29 healthy foals and from all twelve foals with gastrointestinal diseases. The range of viable counts of C. perfringens in the faeces was 10(1)-10(5)/g and in the intestinal specimens 10(1)-10(7)/g. Of 41 isolates of C. perfringens, 37 were considered to be type A. Enterotoxin of the organism was demonstrated in the intestinal contents of five of eight foals with enteric diseases. These findings suggested that C. perfringens is a likely pathogen of foal intestinal diseases.
[Enzootic viral abortion on a stud farm in east Switzerland]. An outbreak of abortion due to the equine herpesvirus-1 (EHV-1) in the eastern part of Switzerland is reviewed. Seven of eleven pregnant mares aborted within twenty-three days in January 1989. Four weeks later another foal died a few minutes after parturition. Three mares delivered live foals in February, March and April without any complications. The examination of the eight dead foals revealed an EHV-1 Infection. The clinical signs and the pathology are discussed. Severe complications during the early post-parturient time are in contrast to the uncomplicated outcome mentioned by other author...
Visceral prolapse after castration in the horse: a review of 18 cases. During a 10 year period, 18 horses were treated surgically because of visceral prolapse after castration. Surgery was successful in six cases of omental prolapse and in eight out of 12 cases of intestinal prolapse. To minimise the risk of visceral prolapse, the authors prefer half-closed castration, with proper ligation of the parietal vaginal tunic, to open castration. If adequate treatment is started promptly, prognosis in cases of visceral prolapse is favourable.
The means of attachment of the larvae of horse, zebra and rhinoceros bot-flies (Diptera: Gasterophilidae). The unusual structure of the mouth hooks of the third instar larvae of the species of Gasterophilus and Gyrostigma, parasites of the alimentary canal of Equideae and Rhinocerotidae respectively, is described.
Temperature sensitivity of equine herpesvirus isolates: a brief review. This article reviews the findings on temperature sensitivity of equine herpesvirus isolates with an emphasis on equine herpesvirus 3, etiological agent of equine coital exanthema. The hypothesis is presented that the relative apathogenic nature of this herpesvirus may be an indirect result of its inability to synthesize and/or process glycoproteins needed by the virus to produce infectious virions at the normal body temperature of its natural host. It is suggested that equine herpesvirus 3 is the more evolved and naturally attenuated member of the equine herpesviruses.
Leiomyosarcoma of the duodenum in two horses. Two horses affected by chronic, intermittent colic were found, at post-mortem examination, to have localized annular thickening of a segment of the duodenum. Histological examination of the lesion in both cases revealed a tumour composed of bundles of oval or spindle-shaped cells that stained as muscle with van Gieson stain. The histological diagnosis was leiomyosarcoma. The tumour had caused partial bowel obstruction in both horses.
