A Rare Case of Vascular Proliferation in the Mandible of a Juvenile Horse.
Abstract: A fast growing, circumscribed, unilateral swelling of the right mandible of a juvenile horse was observed. Within few weeks, the continuously growing mass reached dimensions ranging from 7 to 10 cm in diameter and resulted in loss of the first deciduous premolar of the affected side. The animal was euthanized due to lesion progression. Histologically the mandibular swelling consisted of numerous variably sized vascular structures, partly filled with erythrocytes and embedded in a loosely arranged fibrous stroma within the medullary cavity of the mandible. Juvenile mandibular angiomatosis was diagnosed. To the authors' knowledge this is the first description of this rare entity in the mandible of a foal.
Copyright © 2020 Leitzen, Stumpf, Zimmermann, Bienert-Zeit, Hellige, Baumgärtner and Puff.
Publication Date: 2020-11-11 PubMed ID: 33263011PubMed Central: PMC7685986DOI: 10.3389/fvets.2020.573540Google Scholar: Lookup
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- Case Reports
Summary
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This research article discusses a rare case of vascular proliferation in the lower jaw (mandible) of a young horse. The study suggests that this condition led to the removal of the animal’s first deciduous premolar and ultimately to euthanasia due to the progression of the disease.
Case Presentation
- The research discusses a unique incident where a juvenile horse developed a rapidly escalating, clearly defined swelling on the right side of its mandible. Within weeks, this continuously expanding mass grew to a diameter of 7 to 10 cm, leading to the loss of the first deciduous premolar on the affected side.
- Due to the progression of the lesion, the horse was euthanized. This decision allowed for a thorough histological examination of the irregularity, which would not have been possible while the horse was alive.
Hisological Findings
- Histological examination revealed that the mandibular swelling was composed of numerous variably sized vascular structures—essentially abnormal growth containing multiple blood vessels. Some of these structures were partly filled with erythrocytes, i.e., red blood cells.
- The blood and vascular structures were found within a loosely organized fibrous stroma, acting as the supporting framework that was located inside the medullary, or innermost, cavity of the mandible.
Diagnosis and Significance
- Examining these characteristics, the researchers diagnosed this condition as juvenile mandibular angiomatosis. Angiomatosis generally refers to a condition where there is an abnormal proliferation of blood vessels and, in this case, it occurred in the mandible of a young horse.
- This report is particularly noteworthy due to the rarity of such a case. According to the authors, this is the first description of juvenile mandibular angiomatosis in a foal, shedding light on a condition that has not been previously documented in this context.
Cite This Article
APA
Leitzen E, Stumpf S, Zimmermann C, Bienert-Zeit A, Hellige M, Baumgärtner W, Puff C.
(2020).
A Rare Case of Vascular Proliferation in the Mandible of a Juvenile Horse.
Front Vet Sci, 7, 573540.
https://doi.org/10.3389/fvets.2020.573540 Publication
Researcher Affiliations
- Department of Pathology, University of Veterinary Medicine Hannover, Hannover, Germany.
- Equine Clinic Großmoor, Adelheidsdorf, Germany.
- Equine Clinic Großmoor, Adelheidsdorf, Germany.
- Clinic for Horses, University of Veterinary Medicine Hannover, Hannover, Germany.
- Clinic for Horses, University of Veterinary Medicine Hannover, Hannover, Germany.
- Department of Pathology, University of Veterinary Medicine Hannover, Hannover, Germany.
- Department of Pathology, University of Veterinary Medicine Hannover, Hannover, Germany.
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Citations
This article has been cited 2 times.- Mendes RE, Summers BA, Laovechprasit W, Rissi DR. Widespread central nervous system hemangiomatosis in a donkey. J Vet Diagn Invest 2026 Feb 8;:10406387261418038.
- Rapezzano G, Foote A, Petrini F, Pereira R, Marcatili M. Fetal rhabdomyoma in a Thoroughbred filly. Vet Med Sci 2024 Jul;10(4):e1534.
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