Antimicrobial prescribing guidelines for horses in Australia.
Abstract: The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses. While antimicrobials are commonly used to treat equine infections, complications with therapy are also relatively common. Antimicrobial-associated diarrhoea, immune-mediated diseases, and nephrotoxicity have been reported as sequelae of antimicrobial therapy in equine practice. This does not indicate that clinicians should avoid using these drugs, only that knowledge of the potential for adverse effects is critical when deciding on the most appropriate antimicrobial to use and can assist in avoiding serious side effects, wherever possible, or at least in detecting and responding to them early. These guidelines comprehensively outline key features of infectious diseases in horses, diagnostic testing, and therapeutic guidelines for use in treating horses in Australia.
© 2025 The Author(s). Australian Veterinary Journal published by John Wiley & Sons Australia, Ltd on behalf of Australian Veterinary Association.
Publication Date: 2025-09-03 PubMed ID: 40903020PubMed Central: PMC12674987DOI: 10.1111/avj.70003Google Scholar: Lookup
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- Journal Article
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Cite This Article
APA
Hardefeldt L, Thomas K, Page S, Norris J, Browning G, El Hage C, Stewart A, Gilkerson J, Muscatello G, Verwilghen D, van Galen G, Bauquier J, Cuming R, Reynolds B, Whittaker C, Wilkes E, Clulow J, Burden C, Begg L.
(2025).
Antimicrobial prescribing guidelines for horses in Australia.
Aust Vet J, 103(12), 781-889.
https://doi.org/10.1111/avj.70003 Publication
Researcher Affiliations
- Asia Pacific Centre for Animal Health & National Centre for Antimicrobial Stewardship, Melbourne Veterinary School, University of Melbourne, Melbourne, Victoria, Australia.
- School of Agriculture, Environment and Veterinary Sciences, Charles Sturt University, Bathurst, New South Wales, Australia.
- Advanced Veterinary Therapeutics, Sydney, New South Wales, Australia.
- Sydney School of Veterinary Science, University of Sydney, Sydney, New South Wales, Australia.
- Asia Pacific Centre for Animal Health & National Centre for Antimicrobial Stewardship, Melbourne Veterinary School, University of Melbourne, Melbourne, Victoria, Australia.
- Asia Pacific Centre for Animal Health & National Centre for Antimicrobial Stewardship, Melbourne Veterinary School, University of Melbourne, Melbourne, Victoria, Australia.
- UQ Vets, University of Queensland, St Lucia, Queensland, Australia.
- Asia Pacific Centre for Animal Health & National Centre for Antimicrobial Stewardship, Melbourne Veterinary School, University of Melbourne, Melbourne, Victoria, Australia.
- Sydney School of Veterinary Science, University of Sydney, Sydney, New South Wales, Australia.
- Goulburn Valley Equine Hospital, Congupna, Victoria, Australia.
- Goulburn Valley Equine Hospital, Congupna, Victoria, Australia.
- Melbourne Veterinary School, University of Melbourne, Melbourne, Victoria, Australia.
- Scone Equine Hospital, Scone, New South Wales, Australia.
- Eye Clinic for Animals, Sydney, New South Wales, Australia.
- Eye Clinic for Animals, Sydney, New South Wales, Australia.
- Racing Victoria, Flemington, Victoria, Australia.
- School of Agriculture, Environment and Veterinary Sciences, Charles Sturt University, Bathurst, New South Wales, Australia.
- Strathbogie Veterinary Services, Strathbogie, Victoria, Australia.
- REC Specialist Equine Centre, Sydney, New South Wales, Australia.
MeSH Terms
- Animals
- Anti-Bacterial Agents / therapeutic use
- Anti-Bacterial Agents / adverse effects
- Anti-Infective Agents / therapeutic use
- Anti-Infective Agents / adverse effects
- Antimicrobial Stewardship / standards
- Australia
- Drug Prescriptions / standards
- Drug Prescriptions / veterinary
- Horse Diseases / drug therapy
- Horse Diseases / diagnosis
- Horses
Grant Funding
- Australian Veterinary Association
- Australian Medicines Australia
- Agrifutures Australia
Conflict of Interest Statement
The authors declare no conflicts of interest or sources of funding for the work presented here.
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