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The Canadian veterinary journal = La revue veterinaire canadienne2009; 49(10); 1009-1017;

Concepts for the clinical use of stem cells in equine medicine.

Abstract: Stem cells from various tissues hold great promise for their therapeutic use in horses, but so far efficacy or proof-of-principle has not been established. The basic characteristics and properties of various equine stem cells remain largely unknown, despite their increasingly widespread experimental and empirical commercial use. A better understanding of equine stem cell biology and concepts is needed in order to develop and evaluate rational clinical applications in the horse. Controlled, well-designed studies of the basic biologic characteristics and properties of these cells are needed to move this new equine research field forward. Stem cell research in the horse has exciting equine specific and comparative perspectives that will most likely benefit the health of horses and, potentially, humans. Les cellules souches provenant de différents tissus suscitent de grands espoirs en thérapeutique équine mais jusqu’à maintenant la preuve de leur efficacité ou le principe même de leur utilité n’a pas été établi. Les caractéristiques de base et les propriétés des diverses cellules souches équines demeurent largement inconnues en dépit d’une augmentation des indications expérimentales et d’une utilisation commerciale empirique. Une meilleure compréhension de la biologie des cellules souches équines et des concepts impliqués est nécessaire pour développer et évaluer des applications cliniques rationnelles chez le cheval. Des études contrôlées et bien planifiées sur les caractéristiques et les propriétés biologiques de base de ces cellules sont nécessaires pour faire évoluer ce nouveau champ de recherche. La recherche sur les cellules souches du cheval ouvre des perspectives enlevantes tant pour l’espèce équine que pour la médecine comparative. Ces avancées pourront vraisemblablement améliorer la santé équine et, potentiellement, la santé humaine. (Traduit par Docteur André Blouin)
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Publication Date: 2009-01-03 PubMed ID: 19119371PubMed Central: PMC2553494
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research paper focuses on the potential use of stem cells in equine medicine, underscoring the need for a better understanding of equine stem cell characteristics and biology to develop effective treatments, the efficacy and general principles of which currently remain unproven.

Use of Stem Cells in Equine Medicine

The paper is centered on the premise that using stem cells from various tissues offers a powerful therapeutic potential in treating horses. But, because there’s still a lack of evidence or proof-of-principle to back up this proposition, it requires further investigation to fully realize its applications.

Lack of Knowledge on Equine Stem Cells

  • Despite the increasing instances of experimental and commercial use of stem cells, much about the basic characteristics and properties of different types of equine stem cells continues to be unknown.
  • There is an urgent need for improved understanding and knowledge about the biology and concepts of equine stem cells to develop and evaluate rational clinical applications for horses.

Need for More Research

  • To advance in this field of equine research, there is a necessity for controlled and carefully designed studies geared towards gaining a better understanding of the fundamental biological properties and traits of these cells.
  • Filling these knowledge gaps will contribute to the development of more effective and targeted treatment strategies.

Potential Advantages

  • The use of stem cells in horse treatment could not only improve horse health but might also have implications for human health, reflecting the idea that the research has potential benefits in both equine-specific and comparative contexts.
  • There is an implicit suggestion that a deeper dive into this research area could also contribute to a broader understanding of stem cells and their uses, ultimately benefiting other fields of medicine, including human health.

Cite This Article

APA
Koch TG, Berg LC, Betts DH. (2009). Concepts for the clinical use of stem cells in equine medicine. Can Vet J, 49(10), 1009-1017.

Publication

The Canadian veterinary journal = La revue veterinaire canadienne
ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 49
Issue: 10
Pages: 1009-1017

Researcher Affiliations

Koch, Thomas G
  • Department of Biomedical Sciences, University of Guelph, Guelph, Ontario N1G 2W1. tkoch@uoguelph.ca
Berg, Lise C
    Betts, Dean H

      MeSH Terms

      • Animals
      • Cell Differentiation / physiology
      • Horse Diseases / therapy
      • Horses
      • Stem Cell Transplantation / veterinary
      • Stem Cells / physiology
      • Tissue Engineering / veterinary

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