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Home / Equine Research Bank / Vet Sci / Efficacy of Ozone Bagging Therapy in Equine Chronic Distal L...
Veterinary sciences2025; 13(1); 16; doi: 10.3390/vetsci13010016

Efficacy of Ozone Bagging Therapy in Equine Chronic Distal Limb Wounds: Clinical Evaluation of Eight Cases.

Abstract: Limb wounds in horses represent a significant therapeutic challenge due to poor vascularization, reduced skin elasticity, and high risk of complications such as exuberant granulation tissue. Conventional treatments sometimes fail to provide satisfactory healing outcomes, leading to prolonged recovery and increased costs. This study aimed to evaluate the efficacy of topical ozone therapy using the bagging method in promoting the epithelialization and contraction of chronic distal limb wounds in horses refractory to conventional management. Eight horses, aged 3-21 years, with chronic wounds averaging 48.79 ± 21.20 cm, were treated exclusively with ozone (50 μg/mL) administered by bagging for 30 min every 48 h until complete healing. All cases achieved full wound closure within 27-91 days without systemic medication or major complications. Macroscopic evaluation showed favorable healing, with the restoration of skin pigmentation and hair growth in most cases, while only minimal fibrous scarring was observed in a few patients. Statistical analysis revealed significant improvements in epithelialization, particularly during the last four weeks of treatment. These findings suggest that ozone bagging therapy is a simple, cost-effective, and well-tolerated method that may enhance the healing of chronic distal limb wounds in horses. Further controlled trials are needed to standardize treatment protocols and compare ozone with conventional therapies.
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Publication Date: 2025-12-23 PubMed ID: 41600672PubMed Central: PMC12846506DOI: 10.3390/vetsci13010016Google Scholar: Lookup
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APA
Repciuc CC, Oros NV, Mureșan ȘMC, Sevastre B, Joaquim JGF, Oana LI. (2025). Efficacy of Ozone Bagging Therapy in Equine Chronic Distal Limb Wounds: Clinical Evaluation of Eight Cases. Vet Sci, 13(1), 16. https://doi.org/10.3390/vetsci13010016

Publication

Veterinary sciences
ISSN: 2306-7381
NlmUniqueID: 101680127
Country: Switzerland
Language: English
Volume: 13
Issue: 1
PII: 16

Researcher Affiliations

Repciuc, Călin Cosmin
  • Department of Surgery, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
Oros, Nicușor-Valentin
  • Department of Internal Medicine, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
Mureșan, Ștefana Maria Cristina
  • Department of Surgery, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
Sevastre, Bogdan
  • Department of Pathophysiology, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
Joaquim, Jean Guilherme Fernandes
  • Bioethicus Institute, Botucatu 18605-545, SP, Brazil.
Oana, Liviu-Ioan
  • Department of Surgery, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.

Conflict of Interest Statement

The authors declare no conflicts of interest.

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