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Efficacy of testing for illegal medication in horses.

Abstract: The efficacy of testing for illegal drugs in race horses was surveyed by evaluating 27 questionnaires received from 28 racing jurisdictions polled. Large variations in the number of samples tested and drugs detected were reported. Some jurisdictions reported only illegal medications, whereas others also reported permitted medications. To facilitate comparison, stimulants, depressants, local anesthetics, narcotic analgesics, and tranquilizers were classified as hard drugs. Other drugs, which are legal in some jurisdictions, were classified as soft. To evaluate the efficacy of testing, positive test results were compared for hard drugs only. Positive test results varied from zero in some jurisdictions for some years to 14.8/1,000 samples tested for one small jurisdiction in one year. The mean rates over the years 1975 to 1983 varied from 0.2 to 6.5/1,000, with a modal positive test result of about 1/1,000. Beside the fact that prerace blood testing is less effective than is postrace urine testing, no cause for these variations in the positive test results could be identified. The positive test results also were compared for jurisdictions with differing medication rules for phenylbutazone (PBZ). Jurisdictions that did not allow PBZ had a mean positive test result for hard drugs of about 1.3 +/- 0.9/1,000 samples tested. Jurisdictions that allowed more liberal use of PBZ had a mean positive test result for hard drugs of about 1.3 +/- 1.0/1,000 samples tested. Seemingly, the presence of PBZ in equine forensic samples did not reduce the ability of forensic laboratories to detect the use of hard or illegal drugs.
Publication Date: 1985-11-01 PubMed ID: 4055517
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  • Comparative Study
  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

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The research examines the efficiency of drug testing methods in detecting illegal substances in race horses. The study shows variations across different jurisdictions and didn’t find any correlation between tested drugs prevalence and differing medication rules.

Research Overview

  • The study involves surveys and data collection from 28 horse racing jurisdictions. Questionnaires from these jurisdictions showed variations in both the number of samples tested and drugs detected.
  • The research categorized the drugs into two classes, “hard” drugs, which encompass stimulants, depressants, local anesthetics, narcotic analgesics, and tranquilizers, and “soft” drugs, which are legal in some jurisdictions.
  • The efficacy of drug testing was evaluated by comparing the positive test results of hard drugs only. Here, a considerable difference was noted among multiple jurisdictions over several years (1975-1983).

Testing Efficacy and Phenylbutazone

  • Data from collected samples indicated that pre-race testing with blood samples is less effective than post-race urine testing in detecting illegal drugs.
  • However, the research found no cause for the noted variations in positive drug test results.
  • To evaluate the impact of medication rules on drug test results, jurisdictions with differing policies on Phenylbutazone (PBZ), a common medication in horses, were compared. This research established that the allowance or restriction of PBZ did not significantly affect the rate of positive tests for hard drugs.

Implications

  • The study seemingly indicates that the presence of PBZ in equine forensic samples does not reduce the ability of forensic laboratories to detect the use of hard or illegal drugs.
  • The research suggests that further investigation is required to explore and identify causes for the variations in positive drug test results found in different jurisdictions.

Cite This Article

APA
Woods WE, Chay S, Houston T, Blake JW, Tobin T. (1985). Efficacy of testing for illegal medication in horses. J Am Vet Med Assoc, 187(9), 927-930.

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 187
Issue: 9
Pages: 927-930

Researcher Affiliations

Woods, W E
    Chay, S
      Houston, T
        Blake, J W
          Tobin, T

            MeSH Terms

            • Animals
            • Doping in Sports
            • Greece
            • Horses
            • Iran
            • North America
            • Pharmaceutical Preparations / blood
            • Pharmaceutical Preparations / urine
            • Phenylbutazone / blood
            • Phenylbutazone / urine
            • United Kingdom
            • West Indies

            Citations

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