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Veterinary medicine (Auckland, N.Z.)2019; 10; 69-76; doi: 10.2147/VMRR.S174427

Equine glandular gastric disease: prevalence, impact and management strategies.

Abstract: Equine glandular gastric disease (EGGD) is an increasingly recognized disease of the glandular mucosa of the equine stomach. Diagnosis is confirmed by gastric endoscopy and scored based upon one of several different endoscopic scoring systems. Prevalence appears to be variable, depending upon breed and discipline. Primary identified risk factors include exercise frequency, and stress; therefore, management strategies are focused on reducing exercise and stress. Limiting grain intake and increasing pasture turnout may also be helpful preventative measures. Pharmacologic treatment consists primarily of an approved omeprazole product with or without misoprostol or sucralfate. Further research into the pathophysiology of EGGD may allow for identification of other targeted treatments.
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Publication Date: 2019-07-16 PubMed ID: 31406687PubMed Central: PMC6642651DOI: 10.2147/VMRR.S174427Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

Equine glandular gastric disease (EGGD) is a stomach disease found in horses which varies in prevalence based on factors such as breed and discipline. The study finds that factors including exercise frequency and stress levels may influence the disease, with strategies to mitigate these factors forming the basis of disease management. Dietary alterations and medication appear to be effective preventative and treatment measures, with further research required to identify further target treatments.

Overview of Equine Glandular Gastric Disease

  • The research focuses on Equine Glandular Gastric Disease (EGGD), an increasingly noticeable illness affecting the glandular mucosa located in the horse’s stomach.
  • Diagnosis of EGGD is made through a medical procedure known as a gastric endoscopy wherein a flexible tube with a light and camera at one end is used to view the horse’s stomach.
  • The severity of EGGD is assessed based on various endoscopic scoring systems which grade the condition based on the disease’s magnitude as revealed by the endoscopy.
  • The prevalence of the disease varies, seemingly influenced by factors such as the breed of the horse and their discipline.

Risk Factors and Management Strategies for EGGD

  • The research identifies exercise frequency and stress levels in horses as the primary risk factors for EGGD.
  • Given these risk factors, strategies to manage and prevent the disease largely focus on frequency and intensity of exercise and reduction of stress levels in the horse.
  • Dietary alteration, particularly a reduction in grain intake and an increase in pasture turnout, are identified as potentially helpful preventative measures against EGGD.

Pharmacological Treatment and Future Research for EGGD

  • An approved omeprazole product, either alone or combined with misoprostol or sucralfate, forms the primary basis of pharmacological treatment for EGGD.
  • The study notes that further research into the pathophysiology of EGGD, that is how the disease functions and affects the body, may lead to identification of other possible treatments.
  • By better understanding this, it may be possible to develop more specific, targeted treatments for horses suffering from EGGD.

Cite This Article

APA
Banse HE, Andrews FM. (2019). Equine glandular gastric disease: prevalence, impact and management strategies. Vet Med (Auckl), 10, 69-76. https://doi.org/10.2147/VMRR.S174427

Publication

Veterinary medicine (Auckland, N.Z.)
ISSN: 2230-2034
NlmUniqueID: 101724251
Country: New Zealand
Language: English
Volume: 10
Pages: 69-76

Researcher Affiliations

Banse, Heidi E
  • Equine Health Studies Program, Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge LA, USA.
Andrews, Frank M
  • Equine Health Studies Program, Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge LA, USA.

Conflict of Interest Statement

Dr Banse has previously provided consultancy services for Boehringer Ingelheim Animal Health. Dr Andrews has previously performed research funded by Merial and Boehringer Ingelheim Animal Health. Dr Banse reports grants from Boehringer Ingelheim Animal Health, outside the submitted work. The authors report no other conflicts of interest in this work.

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