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Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)2010; 20(5); 528-532; doi: 10.1111/j.1476-4431.2010.00574.x

European outbreak of atypical myopathy in the autumn 2009.

Abstract: Atypical myopathy is an acute, severe rhabdomyolysis occurring in grazing horses. In the beginning of October 2009, a new outbreak occurred in several European countries. Geographic, demographic and clinical data of the reported cases in the month October 2009 are described. Results: The survival rate in this outbreak was 25%. The most frequently observed clinical signs were congested mucous membranes, dyspnea, tachycardia, depression, weakness, stiffness, recumbency, trembling, sweating, and myoglobinuria. Nonsurvivors were significantly more likely to be recumbent than survivors. Prognostic factors, symptomatic treatment, and preventive measures are discussed. Conclusions: Differences were encountered during the described outbreak of atypical myopathy in October 2009 compared with previous outbreaks reported. Equine practitioners should be aware that previous epidemiological studies have shown that after a high prevalence in the autumn, new cases are likely to occur in the following spring.
Publication Date: 2010-09-21 PubMed ID: 20955305DOI: 10.1111/j.1476-4431.2010.00574.xGoogle Scholar: Lookup
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Summary

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This research article focuses on the 2009 outbreak of atypical myopathy (an acute, severe muscle disease) in grazing horses across various European countries, discussing the geographic, demographic, and clinical data of the cases reported, and offers a comparative overview of this specific outbreak compared to previous ones.

What is Atypical Myopathy?

  • Atypical myopathy is defined as an acute, severe muscle disease—rhabdomyolysis—that impacts grazing horses. It’s a serious condition that terms to result in significant muscle damage, accompanied by symptoms such as muscle weakness, stiffness, and a general state of fatigue.

The 2009 Outbreak

  • In October 2009, a new outbreak of atypical myopathy was reported across several European countries. The research indicates that only 25% of the horses affected by the condition survived the outbreak, highlighting the severity of this affliction.
  • Clinical signs of the disease in this outbreak commonly noted among the afflicted horses were congested mucous membranes, shortness of breath (dyspnea), accelerated heart rate (tachycardia), general signs of distress such as depression and weakness, stiffness, inability to rise (recumbency), trembling, sweating, and the release of muscle proteins into the urine (myoglobinuria).
  • The research found that horses which didn’t survive were significantly more likely to be recumbent, or unable to rise, than surviving horses.

Comparative Analysis and Preventive Measures

  • The researchers compared the 2009 outbreak of atypical myopathy with previous outbreaks, indicating that there were noticeable differences from one outbreak to another.
  • The researchers also discussed the potential prognostic factors, treatment measures to alleviate symptoms, and preventive actions for future outbreaks gleaned from the study of this outbreak.
  • They underscored the need for equine practitioners (veterinarians specializing in horses), to be aware of the possibility of new cases emerging, especially following a high prevalence in the autumn, with fresh cases likely to appear in the following spring.

Cite This Article

APA
Van Galen G, Amory H, Busschers E, Cassart D, De Bruijn M, Gerber V, Keen J, Lefere L, Pitel CM, Marr C, Müller JM, Pineau X, Saegerman C, Sandersen C, Serteyn D, Torfs S, Unger L, Verwilghen D, Votion DM. (2010). European outbreak of atypical myopathy in the autumn 2009. J Vet Emerg Crit Care (San Antonio), 20(5), 528-532. https://doi.org/10.1111/j.1476-4431.2010.00574.x

Publication

ISSN: 1476-4431
NlmUniqueID: 101152804
Country: United States
Language: English
Volume: 20
Issue: 5
Pages: 528-532

Researcher Affiliations

Van Galen, Gaby
  • Equine Teaching Hospital, Faculty of Veterinary Medicine, Liege University, Liege, Belgium. gvangalen@ulg.ac.be
Amory, Helene
    Busschers, Evita
      Cassart, Dominique
        De Bruijn, Marco
          Gerber, Vincent
            Keen, John
              Lefere, Laurence
                Pitel, Christel Marcillaud
                  Marr, Celia
                    Müller, Jessica-M V
                      Pineau, Xavier
                        Saegerman, Claude
                          Sandersen, Charlotte
                            Serteyn, Didier
                              Torfs, Sara
                                Unger, Lucia
                                  Verwilghen, Denis
                                    Votion, Dominique-Marie

                                      MeSH Terms

                                      • Animals
                                      • Disease Outbreaks / veterinary
                                      • Europe / epidemiology
                                      • Female
                                      • Horse Diseases / epidemiology
                                      • Horses
                                      • Male
                                      • Rhabdomyolysis / classification
                                      • Rhabdomyolysis / epidemiology
                                      • Rhabdomyolysis / veterinary
                                      • Seasons
                                      • Time Factors

                                      Citations

                                      This article has been cited 3 times.
                                      1. Jahn P, Dobešová D, Brumarová R, Tóthová K, Kopecká A, Friedecký D. Dynamics of acylcarnitines, hypoglycin A, méthylènecyclopropylglycine and their metabolites in a Kladruber stallion with atypical myopathy. Vet Q 2022 Dec;42(1):183-191.
                                        doi: 10.1080/01652176.2022.2126537pubmed: 36114619google scholar: lookup
                                      2. Westermann CM, van Leeuwen R, van Raamsdonk LW, Mol HG. Hypoglycin A Concentrations in Maple Tree Species in the Netherlands and the Occurrence of Atypical Myopathy in Horses. J Vet Intern Med 2016 May;30(3):880-4.
                                        doi: 10.1111/jvim.13927pubmed: 26995161google scholar: lookup
                                      3. Votion DM. The story of equine atypical myopathy: a review from the beginning to a possible end. ISRN Vet Sci 2012;2012:281018.
                                        doi: 10.5402/2012/281018pubmed: 23762581google scholar: lookup