Ex Vivo Computed Tomographic Evaluation of Morphology Variations in Equine Cervical Vertebrae.
Abstract: Diagnostic imaging is one of the pillars in the clinical workup of horses with clinical signs of cervical spinal disease. An improved awareness of morphologic variations in equine cervical vertebrae would be helpful for interpreting findings. The aim of this anatomic study was to describe CT variations in left-right symmetry and morphology of the cervical and cervicothoracic vertebrae in a sample of horses. Postmortem CT examinations of the cervical spine for horses without congenital growth disorders were prospectively and retrospectively recruited. A total of 78 horses (27 foals, 51 mature horses) were evaluated. Twenty-six horses (33.3%) had homologous changes in which a transposition of the caudal part of the transverse process (caudal ventral tubercle) of C6 toward the ventral aspect of the transverse process of C7 was present (n = 10 bilateral, n = 12 unilateral left-sided, n = 4 unilateral right-sided). There was one horse with occipito-atlantal malformation, two horses with rudimentary first ribs bilaterally, and one horse with bilateral transverse processes at Th1, representing homeotic (transitional) vertebral changes. Chi-square tests identified no significant differences in the number of conformational variations between the group of mature horses with or without clinical signs (P = 0.81) or between the group of mature horses and the group of foals (P = 0.72). Findings indicated that, in this sample of horses, the most frequently identified variations were homologous variations (transposition of the caudal part of the transverse process of C6-C7) in the caudal equine cervical vertebral column. Homeotic (transitional) variations at the cervicothoracic vertebral column were less common.
© 2016 American College of Veterinary Radiology.
Publication Date: 2016-07-20 PubMed ID: 27438135DOI: 10.1111/vru.12393Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
This article explores the minor structural differences found via CT scans in the neck vertebrae of horses, aiming to help identify what is normal variation versus signs of spinal disease. These results show the variety in vertebrae structure between individual horses and suggest these changes are not necessarily indicative of spinal problems.
Research Objective and Methodology
- The primary aim of the study is to provide a better understanding of the normal differences in structure and symmetry of the neck and upper spine (cervical and cervicothoracic vertebrae) in horses. This knowledge would help medical professionals interpret diagnostic imaging results more accurately when looking for signs of spinal disease.
- The study involved detailed examinations of CT scans of the necks of horses after their death. These horses did not have any known growth disorders affecting their spines. Both past and newly conducted CT scans were included in the data.
- A total of 78 horses, 27 foals and 51 mature horses, were included in the study.
Study Findings
- Approximately one-third of the horses had a particular structural difference where a part of the sixth cervical vertebra (C6) was shifted towards the seventh (C7). This change was found in both the left and right sides and in both the bilateral and unilateral forms.
- Instances of other abnormalities such as malformations of the joint between the skull and the first vertebra, unusually small first ribs, and extra bits of bone on the first thoracic vertebra were found less frequently.
- These differences in vertebrae structure were technically classified as ‘homeotic’ or ‘transitional’ changes, indicating changes in structure between two types of vertebrae.
- The researchers found no significant differences in the amount of these variations when comparing horses with or without clinical signs of disease or between younger and older horses.
Conclusions
- The findings from this study imply that the most common variation in the structure of equine neck vertebrae involves a shift in a part of C6 towards C7. This is considered as a normal variation rather than a sign of disease.
- Homeotic or transitional variations at the cervicothoracic spine where the neck meets the upper part of the main spine are less common in horses.
- The study reaffirms the importance of understanding the range of normal structural differences in horse vertebrae. This knowledge is crucial for interpreting CT scans accurately and identifying genuine signs of cervical spinal disease.
Cite This Article
APA
Veraa S, Bergmann W, van den Belt AJ, Wijnberg I, Back W.
(2016).
Ex Vivo Computed Tomographic Evaluation of Morphology Variations in Equine Cervical Vertebrae.
Vet Radiol Ultrasound, 57(5), 482-488.
https://doi.org/10.1111/vru.12393 Publication
Researcher Affiliations
- Division of Diagnostic Imaging, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 110, 3584 CM (Veraa, van den Belt). S.Veraa@uu.nl.
- Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL (Bergmann).
- Division of Diagnostic Imaging, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 110, 3584 CM (Veraa, van den Belt).
- Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 114, 3584 CM (Wijnberg, Back), Utrecht, The Netherlands.
- Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 114, 3584 CM (Wijnberg, Back), Utrecht, The Netherlands.
- Department of Surgery and Anaesthesiology of Domestic Animals, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820, Merelbeke, Belgium (Back).
MeSH Terms
- Animals
- Cadaver
- Cervical Vertebrae / anatomy & histology
- Cervical Vertebrae / diagnostic imaging
- Female
- Horse Diseases / diagnostic imaging
- Horse Diseases / etiology
- Horses / anatomy & histology
- Male
- Prospective Studies
- Reference Values
- Retrospective Studies
- Spinal Diseases / diagnostic imaging
- Spinal Diseases / etiology
- Spinal Diseases / veterinary
- Tomography, X-Ray Computed / veterinary
Citations
This article has been cited 17 times.- May-Davis S, Dzingle D, Saber E, Blades Eckelbarger P. Characterization of the Caudal Ventral Tubercle in the Sixth Cervical Vertebra in Modern Equus ferus caballus. Animals (Basel) 2023 Jul 22;13(14).
- May-Davis S, Hunter R, White R. Morphology of the Ventral Process of the Sixth Cervical Vertebra in Extinct and Extant Equus: Functional Implications. Animals (Basel) 2023 May 17;13(10).
- Scilimati N, Angeli G, Di Meo A, Dall'Aglio C, Pepe M, Beccati F. Post-Mortem Computed Tomographic Features of the Most Caudal Lumbar Vertebrae, Anatomical Variations and Acquired Osseous Pathological Changes, in a Mixed Population of Horses. Animals (Basel) 2023 Feb 19;13(4).
- Kondo T, Sato F, Tsuzuki N, Chen CJ, Yamada K. An objective index for spinal cord compression on computed tomography in Thoroughbred horses. Vet Med Sci 2022 May;8(3):1072-1078.
- Spoormakers TJP, Veraa S, Graat EAM, van Weeren PR, Brommer H. A comparative study of breed differences in the anatomical configuration of the equine vertebral column. J Anat 2021 Oct;239(4):829-838.
- Story MR, Haussler KK, Nout-Lomas YS, Aboellail TA, Kawcak CE, Barrett MF, Frisbie DD, McIlwraith CW. Equine Cervical Pain and Dysfunction: Pathology, Diagnosis and Treatment. Animals (Basel) 2021 Feb 6;11(2).
- Gee C, Small A, Shorter K, Brown WY. A Radiographic Technique for Assessment of Morphologic Variations of the Equine Caudal Cervical Spine. Animals (Basel) 2020 Apr 12;10(4).
- Haussler KK, Pool RR, Clayton HM. Characterization of bony changes localized to the cervical articular processes in a mixed population of horses. PLoS One 2019;14(9):e0222989.
- Veraa S, Bergmann W, Wijnberg ID, Back W, Vernooij H, Nielen M, van den Belt AM. Equine cervical intervertebral disc degeneration is associated with location and MRI features. Vet Radiol Ultrasound 2019 Nov;60(6):696-706.
- Veraa S, de Graaf K, Wijnberg ID, Back W, Vernooij H, Nielen M, Belt AJM. Caudal cervical vertebral morphological variation is not associated with clinical signs in Warmblood horses. Equine Vet J 2020 Mar;52(2):219-224.
- Strootmann T, Peter VG, Körner J. Radiographic Prevalence of Anatomical Variations of the Ventral Lamina of the Sixth Cervical Vertebra, C6/C7 Articular Process Joint Modelling and Competition Outcomes in Warmblood Sport Horses. Animals (Basel) 2026 Jan 29;16(3).
- Ogden NKE, Winderickx K, Bennell A, Stack JD. Computed tomography of the equine caudal spine and pelvis: Technique, image quality and anatomical variation in 56 clinical cases (2018-2023). Equine Vet J 2025 Sep;57(5):1265-1278.
- Dyson S, Phillips K, Zheng S, Aleman M. Congenital variants of the ventral laminae of the sixth and seventh cervical vertebrae are not associated with clinical signs or other radiological abnormalities of the cervicothoracic region in Warmblood horses. Equine Vet J 2025 Mar;57(2):419-430.
- May-Davis S, Eckelbarger PB, Dzingle D, Saber E. Characterization and Association of the Missing Ventral Tubercle(s) from the Sixth Cervical Vertebra and Transpositions on the Ventral Surface of the Seventh Cervical Vertebra in Modern Equus ferus caballus. Animals (Basel) 2024 Jun 20;14(12).
- Olstad K, Bugge MD, Ytrehus B, Kallerud AS. Closure of the neuro-central synchondrosis and other physes in foal cervical spines. Equine Vet J 2025 Jan;57(1):217-231.
- Ros KB, Doveren A, Dreessen C, Pellmann R, Beccati F, Zimmermann E, Distl O. Radiological Methods for the Imaging of Congenital Malformations of C6-T1, the First and Second Sternal Ribs and Development of a Classification System, Demonstrated in Warmblood Horses. Animals (Basel) 2023 Dec 2;13(23).
- Zimmermann E, Ros KB, Pfarrer C, Distl O. Historic Horse Family Displaying Malformations of the Cervicothoracic Junction and Their Connection to Modern German Warmblood Horses. Animals (Basel) 2023 Nov 3;13(21).
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists