Analyze Diet
The Veterinary clinics of North America. Equine practice2001; 16(3); 537-x; doi: 10.1016/s0749-0739(17)30094-9

Factors influencing the international spread of equine diseases.

Abstract: In an era of increasing globalization, the risk of spread of infectious diseases in humans and animals, including equids, has never been greater. International movement of equids and trade in semen are the most important factors responsible for the dissemination of various equine pathogens. Other factors that can or do have the potential to influence the global distribution of equine infectious diseases include: multinational trade agreements, emergent diseases, mutation of pathogens, climate related phenomena, migration of amplifying/reservoir hosts or vectors, availability of new vectors, vaccine contamination and agroterrorism. The relative importance of each of these factors is considered in relation to the spread of equine diseases.
Publication Date: 2001-02-24 PubMed ID: 11219348DOI: 10.1016/s0749-0739(17)30094-9Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
  • Journal Article
  • Review

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article explores various factors contributing to the global spread of equine diseases, emphasizing the role of international equid movement and semen trade, as well as aspects like trade agreements, pathogen mutations, climate-related phenomena, host migration, new vectors, vaccine contamination, and agroterrorism.

Key Factors Responsible for the Spread of Equine Diseases

  • International Movement of Equids and Semen Trade: The study identifies the intercontinental movement of equids and trade in their semen as primary channels for the spread of various equine pathogens. This widespread trade interaction increases the chances and speed of disease transmission from one region to another.
  • Multinational Trade Agreements: The researchers note that international trade agreements can unintentionally aid the spread of diseases. While these agreements aim to boost trade, they often inadvertently facilitate the spread of pathogens by increasing animal and animal product movement across borders.
  • Emergent Diseases and Pathogen Mutations: The emergence of new diseases and mutations of existing pathogens present significant challenges to disease control. Newly evolved or mutated pathogens can quickly spread internationally before effective control or preventive measures are put in place.
  • Climate-Related Phenomena and Host Migration: Alterations in climate can reshape the habitats of vectors or hosts, potentially introducing diseases into new areas. Similarly, the natural migration of reservoir hosts or vectors can spread diseases across geographical borders.
  • New Vectors and Vaccine Contamination: The identification of new vectors, organisms that transmit diseases, can affect the global distribution of equine diseases. Moreover, vaccine contamination, though rare, can unintentionally disseminate infectious agents.
  • Agroterrorism: Intentional spread of diseases, or agroterrorism, is a potential threat to global equine health. By deliberately introducing pathogens into populations or ecosystems, such acts can rapidly disseminate diseases.

Conclusion

The research stresses the multifaceted nature of factors influencing the international spread of equine diseases. Understanding these factors is crucial to devise effective strategies for disease prevention and control. The study pushes for concerted efforts from scientists, governments, and international organizations towards improved disease surveillance, control measures, and international cooperation.

Cite This Article

APA
Timoney PJ. (2001). Factors influencing the international spread of equine diseases. Vet Clin North Am Equine Pract, 16(3), 537-x. https://doi.org/10.1016/s0749-0739(17)30094-9

Publication

ISSN: 0749-0739
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 16
Issue: 3
Pages: 537-x

Researcher Affiliations

Timoney, P J
  • Department of Veterinary Science, Maxwell H. Gluck Equine Research Center, University of Kentucky, Lexington, Kentucky, USA.

MeSH Terms

  • Animal Husbandry
  • Animals
  • Breeding
  • Commerce
  • Communicable Diseases, Emerging / epidemiology
  • Communicable Diseases, Emerging / transmission
  • Communicable Diseases, Emerging / veterinary
  • Disease Vectors
  • Horse Diseases / epidemiology
  • Horse Diseases / transmission
  • Horses
  • International Cooperation
  • Risk Factors
  • Semen

Citations

This article has been cited 11 times.
  1. Câmara RJF, Bueno BL, Resende CF, Balasuriya UBR, Sakamoto SM, Reis JKPD. Viral Diseases that Affect Donkeys and Mules. Animals (Basel) 2020 Nov 25;10(12).
    doi: 10.3390/ani10122203pubmed: 33255568google scholar: lookup
  2. Barba M, Fairbanks EL, Daly JM. Equine viral encephalitis: prevalence, impact, and management strategies. Vet Med (Auckl) 2019;10:99-110.
    doi: 10.2147/VMRR.S168227pubmed: 31497528google scholar: lookup
  3. Carossino M, Dini P, Kalbfleisch TS, Loynachan AT, Canisso IF, Cook RF, Timoney PJ, Balasuriya UBR. Equine arteritis virus long-term persistence is orchestrated by CD8+ T lymphocyte transcription factors, inhibitory receptors, and the CXCL16/CXCR6 axis. PLoS Pathog 2019 Jul;15(7):e1007950.
    doi: 10.1371/journal.ppat.1007950pubmed: 31356622google scholar: lookup
  4. Carossino M, Dini P, Kalbfleisch TS, Loynachan AT, Canisso IF, Shuck KM, Timoney PJ, Cook RF, Balasuriya UBR. Downregulation of MicroRNA eca-mir-128 in Seminal Exosomes and Enhanced Expression of CXCL16 in the Stallion Reproductive Tract Are Associated with Long-Term Persistence of Equine Arteritis Virus. J Virol 2018 May 1;92(9).
    doi: 10.1128/JVI.00015-18pubmed: 29444949google scholar: lookup
  5. Rodriguez L, Reedy S, Nogales A, Murcia PR, Chambers TM, Martinez-Sobrido L. Development of a novel equine influenza virus live-attenuated vaccine. Virology 2018 Mar;516:76-85.
    doi: 10.1016/j.virol.2018.01.005pubmed: 29331866google scholar: lookup
  6. Carossino M, Loynachan AT, Canisso IF, Cook RF, Campos JR, Nam B, Go YY, Squires EL, Troedsson MHT, Swerczek T, Del Piero F, Bailey E, Timoney PJ, Balasuriya UBR. Equine Arteritis Virus Has Specific Tropism for Stromal Cells and CD8(+) T and CD21(+) B Lymphocytes but Not for Glandular Epithelium at the Primary Site of Persistent Infection in the Stallion Reproductive Tract. J Virol 2017 Jul 1;91(13).
    doi: 10.1128/JVI.00418-17pubmed: 28424285google scholar: lookup
  7. Go YY, Bailey E, Timoney PJ, Shuck KM, Balasuriya UB. Evidence that in vitro susceptibility of CD3+ T lymphocytes to equine arteritis virus infection reflects genetic predisposition of naturally infected stallions to become carriers of the virus. J Virol 2012 Nov;86(22):12407-10.
    doi: 10.1128/JVI.01698-12pubmed: 22933293google scholar: lookup
  8. Miszczak F, Shuck KM, Lu Z, Go YY, Zhang J, Sells S, Vabret A, Pronost S, Fortier G, Timoney PJ, Balasuriya UB. Evaluation of two magnetic-bead-based viral nucleic acid purification kits and three real-time reverse transcription-PCR reagent systems in two TaqMan assays for equine arteritis virus detection in semen. J Clin Microbiol 2011 Oct;49(10):3694-6.
    doi: 10.1128/JCM.01187-11pubmed: 21832018google scholar: lookup
  9. Cullinane A, Elton D, Mumford J. Equine influenza - surveillance and control. Influenza Other Respir Viruses 2010 Nov;4(6):339-44.
  10. Ricci I, Rosone F, Pacchiarotti G, Manna G, Cersini A, Carvelli A, La Rocca D, Cammalleri E, Giordani R, Tofani S, Conti R, Rombolà P, Nardini R, Minniti CA, Caforio R, Linardi B, Scicluna MT. Pegiviruses and Coronavirus: Biomolecular Prevalence and Phylogenetic Analysis of Strains Detected in Italian Horse Populations. Viruses 2025 Aug 2;17(8).
    doi: 10.3390/v17081076pubmed: 40872790google scholar: lookup
  11. Lim SI, Kim MJ, Kim MJ, Lee SK, Yang HS, Kwon M, Lim EH, Ouh IO, Kim EJ, Hyun BH, Lee YH. Assessment of Equine Influenza Virus Status in the Republic of Korea from 2020 to 2022. Viruses 2023 Oct 23;15(10).
    doi: 10.3390/v15102135pubmed: 37896912google scholar: lookup