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The Veterinary clinics of North America. Equine practice1989; 5(3); 551-562; doi: 10.1016/s0749-0739(17)30574-6

Management of exuberant granulation tissue.

Abstract: Exuberant granulation tissue is common in large, lower limb wounds of horses, particularly horses of large body size. Methods of control include chemical cautery, cryogenic surgery, and surgical resection. Surgical resection is preferred because it is easy to perform, provides tissue for histologic evaluation, and preserves the epithelial margin. Effective treatments to prevent the formation of granulation tissue include leaving granulating wounds open to the air or, possibly, bandaging with topical steroids. Bandaging or casting may promote exuberant granulation tissue in wounds in which it has already formed, but bandaging and casting are still important in the early management of lower limb or hock wounds in horses. The use of skin grafts or delayed secondary wound closure is frequently necessary to prevent the recurrence of exuberant granulation tissue.
Publication Date: 1989-12-01 PubMed ID: 2691030DOI: 10.1016/s0749-0739(17)30574-6Google Scholar: Lookup
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Summary

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The research article discusses the management strategies for exuberant granulation tissue, a common occurrence in large lower limb wounds of horses. It mentions methods like chemical cautery, cryogenic surgery, surgical resection and the use of skin grafts or delayed secondary wound closures.

Understanding Exuberant Granulation Tissue

Exuberant granulation tissue is a condition common in large, lower limb wounds of horses. It is particularly present in horses with sizable body mass. This condition is a challenge to treating wounds because it interferes with wound healing, often leading to the formation of extra skin tissues, thus affecting the overall recovery of the horse.

Methods of Control

  • Chemical Cautery: This involves the application of a chemical substance to the wound to burn away the excess granulating tissues.
  • Cryogenic Surgery: Also known as cryosurgery, this procedure uses extremely cold temperatures to freeze and destroy abnormal tissue.
  • Surgical Resection: This involves surgical removal of the excessive granulation tissue.

Among these, surgical resection is preferred due to its ease of performance, provision for tissue-for-histologic evaluation and protection of the epithelial margin.

Prevention Focused Treatments

To prevent the formation of granulation tissue, the research suggests leaving granulating wounds open to the air or bandaging them with topical steroids. However, bandaging or casting wounds has been found to potentially promote exuberant granulation tissue in wounds where it has already formed. Despite this, the research suggests that bandaging and casting can still be important during the initial stages of managing lower limb or hock wounds in horses.

Dealing with Recurrence of Granulation Tissue

The use of skin grafts or delayed secondary wound closure are frequently necessary to prevent the recurrence of exuberant granulation tissue. These procedures help to create a protective barrier around the wound, preventing any recurrence and allowing for better healing.

Cite This Article

APA
Bertone AL. (1989). Management of exuberant granulation tissue. Vet Clin North Am Equine Pract, 5(3), 551-562. https://doi.org/10.1016/s0749-0739(17)30574-6

Publication

ISSN: 0749-0739
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 5
Issue: 3
Pages: 551-562

Researcher Affiliations

Bertone, A L
  • Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge.

MeSH Terms

  • Animals
  • Granulation Tissue
  • Horses / injuries
  • Horses / physiology
  • Skin / injuries
  • Skin Physiological Phenomena
  • Wound Healing

References

This article includes 27 references

Citations

This article has been cited 7 times.
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  2. Vicetti Miguel RD, Liu M, Campion GJ, Cherpes TL. Hypothesis: Ephrin-Eph Signaling Pathways Provide Novel Targets for Accelerated Re-Epithelialization of Cutaneous Wounds. Bioessays 2026 Jan;48(1):e70088.
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